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The map label for this gene is cycZ [H]

Identifier: 21228498

GI number: 21228498

Start: 2857959

End: 2858672

Strand: Reverse

Name: cycZ [H]

Synonym: MM_2396

Alternate gene names: 21228498

Gene position: 2858672-2857959 (Counterclockwise)

Preceding gene: 21228499

Following gene: 21228497

Centisome position: 69.79

GC content: 46.5

Gene sequence:

>714_bases
ATGGCCTTAAATTCCAGAAAAATCGGAGTGCTGGCAGGTGCAACTGCCTGCATAATGCTTCTTTCGATGTACATGCTCTT
TTTTTACCTGCCCCCTATCAGGGACGAATCCGGGGAGGTTCTGAGCGGCAGCTTCAGGATCTTTTTCTTCCACATGCCAG
TAGCGGTCATTGCCTATCTGGCTTTTGGAGCCGTATTTGTTGCAAGTATTTTCTACCTGATGAAAAGATCTTTTAAATGG
GATATTTACGCCCGCTCGGCTGCAGAGGTGGGAGTTCTGTTTTCTTTCCTTGTGCTGGTCACCGGGTCTATATGGGCAAA
AGACGCCTGGGGCTGGTACTGGATCTGGGATGTCAGACTGACCACATCTCTTGTCCTTTTTCTTGTTTACCTTGCCTATA
ACATGCTAAGAAAAGCCCTTGAAGAGCCTGAAAAAAGAGCAAGGCTTTCAGCAGTCTTCGGGATTTTAGCTTTCCTTTCC
GTGCCCCTGAGTTTTTTTTCAATAAGGCTCTGGCGCTCGGCTCATCCCCTCATGTTTGGAGGAAGTATGGGAGAAAACGG
AGGAGGACTTGAAGGGACATCGCTCCAGCTGGCTTTGATTGTAAATTTCATAGCTTATTTCCTGCTTTTCCTTACCCTTT
TCTATGTAAAAGTGCAGAATGAGAAGGCAAAAGAGGAGATTGACGCACGCATATCTGTCGGATTAGAAACCTGA

Upstream 100 bases:

>100_bases
TTCACCATTTGCTATAGATACAGATGCTTTCTTTGCGTGTGTTGCCGAACTGTGCTCACAATTAATTTAATCAGTATTTA
ATTTAATAAATGTGAACAAA

Downstream 100 bases:

>100_bases
TTTCTAATGGTCTGTTTTTTCTTTTTTTCAAAAAAAGTCGCATAAGGCCAGGTTTTGCAGCTAATCCGGGTGGTTCAGAG
AAATTGCATCTTACTATCCG

Product: Heme exporter, protein C

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MALNSRKIGVLAGATACIMLLSMYMLFFYLPPIRDESGEVLSGSFRIFFFHMPVAVIAYLAFGAVFVASIFYLMKRSFKW
DIYARSAAEVGVLFSFLVLVTGSIWAKDAWGWYWIWDVRLTTSLVLFLVYLAYNMLRKALEEPEKRARLSAVFGILAFLS
VPLSFFSIRLWRSAHPLMFGGSMGENGGGLEGTSLQLALIVNFIAYFLLFLTLFYVKVQNEKAKEEIDARISVGLET

Sequences:

>Translated_237_residues
MALNSRKIGVLAGATACIMLLSMYMLFFYLPPIRDESGEVLSGSFRIFFFHMPVAVIAYLAFGAVFVASIFYLMKRSFKW
DIYARSAAEVGVLFSFLVLVTGSIWAKDAWGWYWIWDVRLTTSLVLFLVYLAYNMLRKALEEPEKRARLSAVFGILAFLS
VPLSFFSIRLWRSAHPLMFGGSMGENGGGLEGTSLQLALIVNFIAYFLLFLTLFYVKVQNEKAKEEIDARISVGLET
>Mature_236_residues
ALNSRKIGVLAGATACIMLLSMYMLFFYLPPIRDESGEVLSGSFRIFFFHMPVAVIAYLAFGAVFVASIFYLMKRSFKWD
IYARSAAEVGVLFSFLVLVTGSIWAKDAWGWYWIWDVRLTTSLVLFLVYLAYNMLRKALEEPEKRARLSAVFGILAFLSV
PLSFFSIRLWRSAHPLMFGGSMGENGGGLEGTSLQLALIVNFIAYFLLFLTLFYVKVQNEKAKEEIDARISVGLET

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=163, Percent_Identity=27.6073619631902, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 26778; Mature: 26647

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNSRKIGVLAGATACIMLLSMYMLFFYLPPIRDESGEVLSGSFRIFFFHMPVAVIAYL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCEEEEEHHHHHHHHHHH
AFGAVFVASIFYLMKRSFKWDIYARSAAEVGVLFSFLVLVTGSIWAKDAWGWYWIWDVRL
HHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEHHHH
TTSLVLFLVYLAYNMLRKALEEPEKRARLSAVFGILAFLSVPLSFFSIRLWRSAHPLMFG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
GSMGENGGGLEGTSLQLALIVNFIAYFLLFLTLFYVKVQNEKAKEEIDARISVGLET
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ALNSRKIGVLAGATACIMLLSMYMLFFYLPPIRDESGEVLSGSFRIFFFHMPVAVIAYL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCEEEEEHHHHHHHHHHH
AFGAVFVASIFYLMKRSFKWDIYARSAAEVGVLFSFLVLVTGSIWAKDAWGWYWIWDVRL
HHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEHHHH
TTSLVLFLVYLAYNMLRKALEEPEKRARLSAVFGILAFLSVPLSFFSIRLWRSAHPLMFG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
GSMGENGGGLEGTSLQLALIVNFIAYFLLFLTLFYVKVQNEKAKEEIDARISVGLET
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]