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The map label for this gene is trxB [H]

Identifier: 21228455

GI number: 21228455

Start: 2812084

End: 2813001

Strand: Reverse

Name: trxB [H]

Synonym: MM_2353

Alternate gene names: 21228455

Gene position: 2813001-2812084 (Counterclockwise)

Preceding gene: 21228456

Following gene: 21228453

Centisome position: 68.67

GC content: 45.97

Gene sequence:

>918_bases
ATGTACGACCTGATTATTATAGGAGGGGGACCTGCGGGACTTACTGCAGGGATTTACGCTGTGCGTTATGGACTTGATAC
CCTTATTCTGGAGAGAAATGAGATCAGCGGCCAGATCTCAATGGCGGATATTGTGGAGAACTACCCCGGTTTTCCATCGA
TTTCGGGGCTTGAACTCATGGAAAGATTTAGAACACATGCTCAGGAGGTAGGGGTAAAAACCACAATTACAGAGGTTCTT
TCAGTCAGGTCTGAAGGAACAAAGAAAATTATTACAACGGACAGTGGGGACCTCGAGGCAAAAGCCGTAATAATTGCCAC
AGGCGCAAATCCAAAACACCTTGGCGTTCCGGGAGAGAAAGAGCTGATCAGTAAGGGAGTCTCCTACTGTGCGATATGTG
ACGGGCCTTTTTTCAGAAACAAAATTGTAGCCGTCGTAGGAGGCGGCAACTCCGCTGTTACAGATGCTCTTTTCCTGTCA
AAAGTTGCCCAGAAGGTATATCTTGTCCACAGGCGGGACCATTTGAAAGCTGCCAGGGTCCTTCAGGACAGGGTTGACGG
AACTCCAAATATCGAGTTAATACTCAATTCGCACGTCCTGGAAATAGTTGGGACCAGGGAAGGAATTAAAAAAGTCGAAA
AAATTATCCTGGAAGATGTTAACAGTAGAGAAACCCGTGAGCTTTCTACCAATGGCGTTTTTATCTATGTAGGAATCCAC
CCGAATACCGAATTCGTGGATGTTGAAAAAGATGAAGGAGGCTTCATCAAAACAGACCGCTGGATGGAAACCTCAGAGAA
AGGGATTTATGCAGCAGGAGATTGTCGTGATACTCCCATCTGGCAACTTGTAACAGCGGTAAGAGATGGGGCAATTGCAG
CCACAGCCGCATATGAATACATTGAGAAAATTAGATGA

Upstream 100 bases:

>100_bases
TTACAGGGCTTCCTAAAAAAGCCGAGGCAATAGCCCGTATTACATGAAAGCAGATTAAAATTTACTTTTTGAACACATTT
CTATTTTCTGGAGGTTATAT

Downstream 100 bases:

>100_bases
AAAATGTAGAAGAATAAGAAAAGTATTGTAAAAAATGACCAGGGCAGGAGGACGATAAAGAAAGCTCGCCTCAAAAGTAA
ATCCAGAACGAACACTAATC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MYDLIIIGGGPAGLTAGIYAVRYGLDTLILERNEISGQISMADIVENYPGFPSISGLELMERFRTHAQEVGVKTTITEVL
SVRSEGTKKIITTDSGDLEAKAVIIATGANPKHLGVPGEKELISKGVSYCAICDGPFFRNKIVAVVGGGNSAVTDALFLS
KVAQKVYLVHRRDHLKAARVLQDRVDGTPNIELILNSHVLEIVGTREGIKKVEKIILEDVNSRETRELSTNGVFIYVGIH
PNTEFVDVEKDEGGFIKTDRWMETSEKGIYAAGDCRDTPIWQLVTAVRDGAIAATAAYEYIEKIR

Sequences:

>Translated_305_residues
MYDLIIIGGGPAGLTAGIYAVRYGLDTLILERNEISGQISMADIVENYPGFPSISGLELMERFRTHAQEVGVKTTITEVL
SVRSEGTKKIITTDSGDLEAKAVIIATGANPKHLGVPGEKELISKGVSYCAICDGPFFRNKIVAVVGGGNSAVTDALFLS
KVAQKVYLVHRRDHLKAARVLQDRVDGTPNIELILNSHVLEIVGTREGIKKVEKIILEDVNSRETRELSTNGVFIYVGIH
PNTEFVDVEKDEGGFIKTDRWMETSEKGIYAAGDCRDTPIWQLVTAVRDGAIAATAAYEYIEKIR
>Mature_305_residues
MYDLIIIGGGPAGLTAGIYAVRYGLDTLILERNEISGQISMADIVENYPGFPSISGLELMERFRTHAQEVGVKTTITEVL
SVRSEGTKKIITTDSGDLEAKAVIIATGANPKHLGVPGEKELISKGVSYCAICDGPFFRNKIVAVVGGGNSAVTDALFLS
KVAQKVYLVHRRDHLKAARVLQDRVDGTPNIELILNSHVLEIVGTREGIKKVEKIILEDVNSRETRELSTNGVFIYVGIH
PNTEFVDVEKDEGGFIKTDRWMETSEKGIYAAGDCRDTPIWQLVTAVRDGAIAATAAYEYIEKIR

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=311, Percent_Identity=36.6559485530547, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI87081763, Length=308, Percent_Identity=36.6883116883117, Blast_Score=173, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6321898, Length=316, Percent_Identity=38.6075949367089, Blast_Score=194, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6320560, Length=317, Percent_Identity=36.2776025236593, Blast_Score=187, Evalue=2e-48,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33280; Mature: 33280

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDLIIIGGGPAGLTAGIYAVRYGLDTLILERNEISGQISMADIVENYPGFPSISGLELM
CEEEEEECCCCHHHHHHHHHHHHCCHHEEEECCCCCCCEEHHHHHHCCCCCCCCCHHHHH
ERFRTHAQEVGVKTTITEVLSVRSEGTKKIITTDSGDLEAKAVIIATGANPKHLGVPGEK
HHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEECCCCCCCCCCCHH
ELISKGVSYCAICDGPFFRNKIVAVVGGGNSAVTDALFLSKVAQKVYLVHRRDHLKAARV
HHHHCCCCEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQDRVDGTPNIELILNSHVLEIVGTREGIKKVEKIILEDVNSRETRELSTNGVFIYVGIH
HHHHCCCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCHHHEECCCCEEEEEEEC
PNTEFVDVEKDEGGFIKTDRWMETSEKGIYAAGDCRDTPIWQLVTAVRDGAIAATAAYEY
CCCEEEEEECCCCCEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHH
IEKIR
HHHCC
>Mature Secondary Structure
MYDLIIIGGGPAGLTAGIYAVRYGLDTLILERNEISGQISMADIVENYPGFPSISGLELM
CEEEEEECCCCHHHHHHHHHHHHCCHHEEEECCCCCCCEEHHHHHHCCCCCCCCCHHHHH
ERFRTHAQEVGVKTTITEVLSVRSEGTKKIITTDSGDLEAKAVIIATGANPKHLGVPGEK
HHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEECCCCCCCCCCCHH
ELISKGVSYCAICDGPFFRNKIVAVVGGGNSAVTDALFLSKVAQKVYLVHRRDHLKAARV
HHHHCCCCEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQDRVDGTPNIELILNSHVLEIVGTREGIKKVEKIILEDVNSRETRELSTNGVFIYVGIH
HHHHCCCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCHHHEECCCCEEEEEEEC
PNTEFVDVEKDEGGFIKTDRWMETSEKGIYAAGDCRDTPIWQLVTAVRDGAIAATAAYEY
CCCEEEEEECCCCCEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHH
IEKIR
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA