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The map label for this gene is phoP [H]

Identifier: 21228453

GI number: 21228453

Start: 2810718

End: 2811230

Strand: Reverse

Name: phoP [H]

Synonym: MM_2351

Alternate gene names: 21228453

Gene position: 2811230-2810718 (Counterclockwise)

Preceding gene: 21228455

Following gene: 21228452

Centisome position: 68.63

GC content: 40.74

Gene sequence:

>513_bases
ATGTATAACAATACTCTTAACCATGAAATATTAAAACTTATAAAAGAACAGCCAGAAATAAGCGAGAAGAATATTGCACG
TACGCTTTCAATTACGGAAGATGCGGTAAAAGCCCGGCTTGCAGACCTGAGGGACGTCAGGGATAAAATCCTGATAATGG
GTAATGGGCATAATAACTACCATAACCTCAGAAATGAGCTGGAAGCTGAAAATTACAATGTCGTTAATGTCTCAGATGCC
TTATTAGCCCTTGAAACCGTAAAAGAAGAGAGACCTGACATTGTACTTCTTGATACAGCTTCCCTTAATGCAGACGGTTT
TGAGATTTGCAGGCAGCTTAAGGCTAATCCGAAATGCTGGTGGATTCCTATTATGGTCCTGAGTGAAAGAAATAAAGCAG
AAGACAGCATTAAAGCCTTCAAGTCCGGAGCCGATGACTTTATTTCCACACCGTTCAATACTCTGGAACTGAGAGCCAGA
GTTGGAATGGTTTTGAGACGTAGCCGTATTTAA

Upstream 100 bases:

>100_bases
CCTCGAATTACTGTGTACATTTTTGGATACACTCTTCGTTTTAAAATTTGAGAAATGTTTAATAACTAAGAAAATATATA
CTGTATGAGGTGGAGGGAAA

Downstream 100 bases:

>100_bases
ATCCTGAAAATGATTTATTATCGAGAATCGGTGATAATCCTGCAAACTATCTAGATTGAAAAAGGCGAAATCTCCTTTCT
TTCCCTTTTCAGACCTGATA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MYNNTLNHEILKLIKEQPEISEKNIARTLSITEDAVKARLADLRDVRDKILIMGNGHNNYHNLRNELEAENYNVVNVSDA
LLALETVKEERPDIVLLDTASLNADGFEICRQLKANPKCWWIPIMVLSERNKAEDSIKAFKSGADDFISTPFNTLELRAR
VGMVLRRSRI

Sequences:

>Translated_170_residues
MYNNTLNHEILKLIKEQPEISEKNIARTLSITEDAVKARLADLRDVRDKILIMGNGHNNYHNLRNELEAENYNVVNVSDA
LLALETVKEERPDIVLLDTASLNADGFEICRQLKANPKCWWIPIMVLSERNKAEDSIKAFKSGADDFISTPFNTLELRAR
VGMVLRRSRI
>Mature_170_residues
MYNNTLNHEILKLIKEQPEISEKNIARTLSITEDAVKARLADLRDVRDKILIMGNGHNNYHNLRNELEAENYNVVNVSDA
LLALETVKEERPDIVLLDTASLNADGFEICRQLKANPKCWWIPIMVLSERNKAEDSIKAFKSGADDFISTPFNTLELRAR
VGMVLRRSRI

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=107, Percent_Identity=35.5140186915888, Blast_Score=70, Evalue=5e-14,
Organism=Escherichia coli, GI1790860, Length=124, Percent_Identity=29.8387096774194, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786599, Length=101, Percent_Identity=33.6633663366337, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787375, Length=107, Percent_Identity=29.9065420560748, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 19433; Mature: 19433

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNNTLNHEILKLIKEQPEISEKNIARTLSITEDAVKARLADLRDVRDKILIMGNGHNNY
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCH
HNLRNELEAENYNVVNVSDALLALETVKEERPDIVLLDTASLNADGFEICRQLKANPKCW
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCEE
WIPIMVLSERNKAEDSIKAFKSGADDFISTPFNTLELRARVGMVLRRSRI
EEEEEEECCCCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYNNTLNHEILKLIKEQPEISEKNIARTLSITEDAVKARLADLRDVRDKILIMGNGHNNY
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCH
HNLRNELEAENYNVVNVSDALLALETVKEERPDIVLLDTASLNADGFEICRQLKANPKCW
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCEE
WIPIMVLSERNKAEDSIKAFKSGADDFISTPFNTLELRARVGMVLRRSRI
EEEEEEECCCCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]