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The map label for this gene is hypE [C]

Identifier: 21228421

GI number: 21228421

Start: 2775715

End: 2776761

Strand: Direct

Name: hypE [C]

Synonym: MM_2319

Alternate gene names: 21228421

Gene position: 2775715-2776761 (Clockwise)

Preceding gene: 21228420

Following gene: 21228422

Centisome position: 67.76

GC content: 48.04

Gene sequence:

>1047_bases
ATGAAATCCAATACAATTTCTCTCGAACACGGCGCCGGTGGAGAGGTAATGCAGGCGCTTATAGGAGATATTATTCTCAA
AAACTTCCGTAATAAAAGTGCAGGTTCTATAGGCCTTGACAGCCTTGATGACGGGTCCACAGTCAGACTTGAGAACTTTA
ACTCTTCTTCCGAACTTGTGCTGACAACGGACAGCCATGTGATAACTCCTGCTTTTTTTCCTGATACGAATATAGGCAGG
CTTGCTGTTGCAGGTACAATCAATGATCTGACAGTCATGGGAGCAAAACCGCTTGCACTCACCTGTGCAGTCATAATGCC
TGAAGGTTTTCCAGTCCATGATTTTGAAGAGATTATAAAAACAATGGACCAGACTGCTGCGGAGGCTGGAGTGCCCATAA
TCACAGGCGATACGAAAACCGTGGAAAAGACCGCACTTGATTCAATCATCCTTAACACCGCAGGTCTCGGGATTACGGAC
AGCCCTGTAAGAGACTCAGGTCTTAAGCCAGGAGACAGGATCATCGTTACAGGCACCATAGGGGATCATGGGATCTCTCT
TATGGCCCACAGGGAAGGTTTTGATTTTGATACTGACCTTGTTTCTGATTCCGCTCCCCTGTGGAAGTTAATAGAACCGG
TCCTTAAACTCCGGACTCCTCAGGGAGAGCCTGTAATAACGGCTATGAAAGACCCTACCCGCGGGGGGCTTGCAAACGCT
CTTAATGAAATGGCAGAAAAATCCGGAGCAGGAATCCTGCTTGAAGAAAGCCTCATCCCTTACAAGCCTGCAGTGACTGC
AGCCTGTGAGATGCTGGGTCTTGATCCTCTCGAAGTTGCAAATGAAGGAAAAGCAATTATAGGGGTCAAAGCCGGCTTTG
AAGAAGACGTACTTTCAATTCTCAGGCAGCACCCCTACGGAAAGGATGCAGCCCTTATAGGAGAGGTCACTGATGAAAAC
AAAGGAGAGGTAATCCTGAGGAACCGTTTCGGTGGGATGCGTTATGTGGACGTGCCTGCAGGAGACCCGATTCCGAGAGT
CTGTTAA

Upstream 100 bases:

>100_bases
CTGGGAAAGCCTTGAAACATGGATAGGTTTCATCGAGAGCGGACTTGAAAAACGCACTAAATAAACTTAATAGAGTCTTA
CGAGGATAAAGGAGCTTTAG

Downstream 100 bases:

>100_bases
CATAATGAGAAGACACAATGAGAATATACTGACAGATTTTATTTCTCCCAACTTCTATTTTTCCCGGGTTGATTTATTCA
AACTTCTACCCGGGACCCTA

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKSNTISLEHGAGGEVMQALIGDIILKNFRNKSAGSIGLDSLDDGSTVRLENFNSSSELVLTTDSHVITPAFFPDTNIGR
LAVAGTINDLTVMGAKPLALTCAVIMPEGFPVHDFEEIIKTMDQTAAEAGVPIITGDTKTVEKTALDSIILNTAGLGITD
SPVRDSGLKPGDRIIVTGTIGDHGISLMAHREGFDFDTDLVSDSAPLWKLIEPVLKLRTPQGEPVITAMKDPTRGGLANA
LNEMAEKSGAGILLEESLIPYKPAVTAACEMLGLDPLEVANEGKAIIGVKAGFEEDVLSILRQHPYGKDAALIGEVTDEN
KGEVILRNRFGGMRYVDVPAGDPIPRVC

Sequences:

>Translated_348_residues
MKSNTISLEHGAGGEVMQALIGDIILKNFRNKSAGSIGLDSLDDGSTVRLENFNSSSELVLTTDSHVITPAFFPDTNIGR
LAVAGTINDLTVMGAKPLALTCAVIMPEGFPVHDFEEIIKTMDQTAAEAGVPIITGDTKTVEKTALDSIILNTAGLGITD
SPVRDSGLKPGDRIIVTGTIGDHGISLMAHREGFDFDTDLVSDSAPLWKLIEPVLKLRTPQGEPVITAMKDPTRGGLANA
LNEMAEKSGAGILLEESLIPYKPAVTAACEMLGLDPLEVANEGKAIIGVKAGFEEDVLSILRQHPYGKDAALIGEVTDEN
KGEVILRNRFGGMRYVDVPAGDPIPRVC
>Mature_348_residues
MKSNTISLEHGAGGEVMQALIGDIILKNFRNKSAGSIGLDSLDDGSTVRLENFNSSSELVLTTDSHVITPAFFPDTNIGR
LAVAGTINDLTVMGAKPLALTCAVIMPEGFPVHDFEEIIKTMDQTAAEAGVPIITGDTKTVEKTALDSIILNTAGLGITD
SPVRDSGLKPGDRIIVTGTIGDHGISLMAHREGFDFDTDLVSDSAPLWKLIEPVLKLRTPQGEPVITAMKDPTRGGLANA
LNEMAEKSGAGILLEESLIPYKPAVTAACEMLGLDPLEVANEGKAIIGVKAGFEEDVLSILRQHPYGKDAALIGEVTDEN
KGEVILRNRFGGMRYVDVPAGDPIPRVC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=348, Percent_Identity=42.2413793103448, Blast_Score=267, Evalue=8e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36839; Mature: 36839

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNTISLEHGAGGEVMQALIGDIILKNFRNKSAGSIGLDSLDDGSTVRLENFNSSSELV
CCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCEE
LTTDSHVITPAFFPDTNIGRLAVAGTINDLTVMGAKPLALTCAVIMPEGFPVHDFEEIIK
EEECCCEEEEEECCCCCCCCEEEEECCCCEEEECCCCHHEEEEEECCCCCCCHHHHHHHH
TMDQTAAEAGVPIITGDTKTVEKTALDSIILNTAGLGITDSPVRDSGLKPGDRIIVTGTI
HHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECC
GDHGISLMAHREGFDFDTDLVSDSAPLWKLIEPVLKLRTPQGEPVITAMKDPTRGGLANA
CCCCEEEEEECCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
LNEMAEKSGAGILLEESLIPYKPAVTAACEMLGLDPLEVANEGKAIIGVKAGFEEDVLSI
HHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHCCCCCEEEEEECCCHHHHHHH
LRQHPYGKDAALIGEVTDENKGEVILRNRFGGMRYVDVPAGDPIPRVC
HHHCCCCCCCEEEEECCCCCCCCEEEEECCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKSNTISLEHGAGGEVMQALIGDIILKNFRNKSAGSIGLDSLDDGSTVRLENFNSSSELV
CCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCEE
LTTDSHVITPAFFPDTNIGRLAVAGTINDLTVMGAKPLALTCAVIMPEGFPVHDFEEIIK
EEECCCEEEEEECCCCCCCCEEEEECCCCEEEECCCCHHEEEEEECCCCCCCHHHHHHHH
TMDQTAAEAGVPIITGDTKTVEKTALDSIILNTAGLGITDSPVRDSGLKPGDRIIVTGTI
HHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECC
GDHGISLMAHREGFDFDTDLVSDSAPLWKLIEPVLKLRTPQGEPVITAMKDPTRGGLANA
CCCCEEEEEECCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
LNEMAEKSGAGILLEESLIPYKPAVTAACEMLGLDPLEVANEGKAIIGVKAGFEEDVLSI
HHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHCCCCCEEEEEECCCHHHHHHH
LRQHPYGKDAALIGEVTDENKGEVILRNRFGGMRYVDVPAGDPIPRVC
HHHCCCCCCCEEEEECCCCCCCCEEEEECCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]