Click here to switch to the map view.

The map label for this gene is hypD [C]

Identifier: 21228418

GI number: 21228418

Start: 2773442

End: 2774578

Strand: Direct

Name: hypD [C]

Synonym: MM_2316

Alternate gene names: 21228418

Gene position: 2773442-2774578 (Clockwise)

Preceding gene: 21228417

Following gene: 21228419

Centisome position: 67.71

GC content: 44.24

Gene sequence:

>1137_bases
GTGGACGCTGATAATATGGAAAACGGAAAATCTCTTTCAAAAACAGCGGTTTCAGACATAGAAAAGAAACTCCTTGAAAG
GATTAAAGGTTCTGAGGTATCACTTCGTATTATGCATGTCTGTGGAACGCACGAAAGAACCATAGCAAAATACGGGTTAA
GAAGTGTGCTTCCTCAGTATATTGAAGTAATAAGTGGTCCCGGCTGCCCTGTCTGTGTCACTCCTGAAAGAGATATTGAC
ATTGCAATTGCCCTCGCAAAGAGCGGAGCAACTGTGGTCACTTTCGGGGATATGATGCGAGTACCTGGCTCTTCAGACAG
CCTCCTGAACGCAAAGTCTGAAGGGGCGGATGTAAGGATGGTTTACAGTATAGATGATGCAGTTGCCCTTGCAGGAAAAA
AGCCAGATCTGAAAGTAGTCTTTTTCGGGATAGGTTTTGAGACCACAGTCCCTGCAAACGCGGCAGCCCTTTTGCGGAAG
GATCTACCTGACAACTTCAGCCTCCTTGCTTCTCAGAAGCAGACTCCTCCTGCAGTCAATCTTCTTGCCAGTGATACCAA
TGTTGATGCTTTTATAGCACCAGGGCATGTGGCAACCATAATAGGCACAGAACCTTTCGAACCGCTTGCAAAAAAGGGCT
TTCCTGTTGTTGTTAGTGGATTTGAAGCCGCAGATATACTTCTTGGAATAAACATCTTACAGATGCAGGTAGAGAAAGGA
ATCTCAAGGGTGGACAACGGATATCCCAGGGTCGTAAAGCCAGAAGGAAATACAATAGCCCTGAAAATGATGGATGAGGT
ATTCAAAACTTCTGACTCTGAGTGGAGAGGTATAGGAAATATAGAAGATTCGGGACTCGTCCTCAGGGAAGAGTTTGAAG
AAAAAGACGCTGCGAAAATACATGAAGATCTTTATTCTGCTTCTCTTGCAGAGATAAAATCGAAAGCTGAAGGAAAAGAT
AAAAAACGCTGCATCTGTGCAGCTATCCTGACAGGAAAAGCAAAACCTTCCCAGTGTCCTAACTTCGGGAAAGAATGCAC
TCCAAAAAAACCAGCGGGTCCCTGCATGGTAAGTCAGGAAGGTATGTGCTATAACTGGTATAAATATTCTCGAGAAGGAG
GTAGTAAAAATGCATGA

Upstream 100 bases:

>100_bases
CTGAGATTTCGGAAGAAGAAAGTGAAGAAACCATGCGCCTTCTCAAGATTATGGCCGGTCTCGAAGAAATTGACTCCCTT
GAAAGTGAATCTCAGTGAAA

Downstream 100 bases:

>100_bases
ACTTTCCATTGCCTGTGAAATCTTTGAGCAGGTTAAGGTTACTGCCGAAGCTCACGGAGCCACAGAAGTCAAACATGTGA
CTCTTCAAATGGGAAGGCTG

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MDADNMENGKSLSKTAVSDIEKKLLERIKGSEVSLRIMHVCGTHERTIAKYGLRSVLPQYIEVISGPGCPVCVTPERDID
IAIALAKSGATVVTFGDMMRVPGSSDSLLNAKSEGADVRMVYSIDDAVALAGKKPDLKVVFFGIGFETTVPANAAALLRK
DLPDNFSLLASQKQTPPAVNLLASDTNVDAFIAPGHVATIIGTEPFEPLAKKGFPVVVSGFEAADILLGINILQMQVEKG
ISRVDNGYPRVVKPEGNTIALKMMDEVFKTSDSEWRGIGNIEDSGLVLREEFEEKDAAKIHEDLYSASLAEIKSKAEGKD
KKRCICAAILTGKAKPSQCPNFGKECTPKKPAGPCMVSQEGMCYNWYKYSREGGSKNA

Sequences:

>Translated_378_residues
MDADNMENGKSLSKTAVSDIEKKLLERIKGSEVSLRIMHVCGTHERTIAKYGLRSVLPQYIEVISGPGCPVCVTPERDID
IAIALAKSGATVVTFGDMMRVPGSSDSLLNAKSEGADVRMVYSIDDAVALAGKKPDLKVVFFGIGFETTVPANAAALLRK
DLPDNFSLLASQKQTPPAVNLLASDTNVDAFIAPGHVATIIGTEPFEPLAKKGFPVVVSGFEAADILLGINILQMQVEKG
ISRVDNGYPRVVKPEGNTIALKMMDEVFKTSDSEWRGIGNIEDSGLVLREEFEEKDAAKIHEDLYSASLAEIKSKAEGKD
KKRCICAAILTGKAKPSQCPNFGKECTPKKPAGPCMVSQEGMCYNWYKYSREGGSKNA
>Mature_378_residues
MDADNMENGKSLSKTAVSDIEKKLLERIKGSEVSLRIMHVCGTHERTIAKYGLRSVLPQYIEVISGPGCPVCVTPERDID
IAIALAKSGATVVTFGDMMRVPGSSDSLLNAKSEGADVRMVYSIDDAVALAGKKPDLKVVFFGIGFETTVPANAAALLRK
DLPDNFSLLASQKQTPPAVNLLASDTNVDAFIAPGHVATIIGTEPFEPLAKKGFPVVVSGFEAADILLGINILQMQVEKG
ISRVDNGYPRVVKPEGNTIALKMMDEVFKTSDSEWRGIGNIEDSGLVLREEFEEKDAAKIHEDLYSASLAEIKSKAEGKD
KKRCICAAILTGKAKPSQCPNFGKECTPKKPAGPCMVSQEGMCYNWYKYSREGGSKNA

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=349, Percent_Identity=43.5530085959885, Blast_Score=274, Evalue=9e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 40721; Mature: 40721

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDADNMENGKSLSKTAVSDIEKKLLERIKGSEVSLRIMHVCGTHERTIAKYGLRSVLPQY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHH
IEVISGPGCPVCVTPERDIDIAIALAKSGATVVTFGDMMRVPGSSDSLLNAKSEGADVRM
HHHHCCCCCCEEECCCCCCEEEEEEECCCCEEEEECCEEECCCCCCCCCCCCCCCCCEEE
VYSIDDAVALAGKKPDLKVVFFGIGFETTVPANAAALLRKDLPDNFSLLASQKQTPPAVN
EEECCCHHEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCCEE
LLASDTNVDAFIAPGHVATIIGTEPFEPLAKKGFPVVVSGFEAADILLGINILQMQVEKG
EEECCCCCCEEECCCCEEEEECCCCCCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHH
ISRVDNGYPRVVKPEGNTIALKMMDEVFKTSDSEWRGIGNIEDSGLVLREEFEEKDAAKI
HHHHCCCCCEEECCCCCEEEEEEHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHH
HEDLYSASLAEIKSKAEGKDKKRCICAAILTGKAKPSQCPNFGKECTPKKPAGPCMVSQE
HHHHHHHHHHHHHHHHCCCCHHHEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCEEECCC
GMCYNWYKYSREGGSKNA
CCEEEHEEECCCCCCCCC
>Mature Secondary Structure
MDADNMENGKSLSKTAVSDIEKKLLERIKGSEVSLRIMHVCGTHERTIAKYGLRSVLPQY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHH
IEVISGPGCPVCVTPERDIDIAIALAKSGATVVTFGDMMRVPGSSDSLLNAKSEGADVRM
HHHHCCCCCCEEECCCCCCEEEEEEECCCCEEEEECCEEECCCCCCCCCCCCCCCCCEEE
VYSIDDAVALAGKKPDLKVVFFGIGFETTVPANAAALLRKDLPDNFSLLASQKQTPPAVN
EEECCCHHEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCCEE
LLASDTNVDAFIAPGHVATIIGTEPFEPLAKKGFPVVVSGFEAADILLGINILQMQVEKG
EEECCCCCCEEECCCCEEEEECCCCCCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHH
ISRVDNGYPRVVKPEGNTIALKMMDEVFKTSDSEWRGIGNIEDSGLVLREEFEEKDAAKI
HHHHCCCCCEEECCCCCEEEEEEHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHH
HEDLYSASLAEIKSKAEGKDKKRCICAAILTGKAKPSQCPNFGKECTPKKPAGPCMVSQE
HHHHHHHHHHHHHHHHCCCCHHHEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCEEECCC
GMCYNWYKYSREGGSKNA
CCEEEHEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]