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The map label for this gene is hypC [C]

Identifier: 21228417

GI number: 21228417

Start: 2773179

End: 2773439

Strand: Direct

Name: hypC [C]

Synonym: MM_2315

Alternate gene names: 21228417

Gene position: 2773179-2773439 (Clockwise)

Preceding gene: 21228413

Following gene: 21228418

Centisome position: 67.7

GC content: 42.15

Gene sequence:

>261_bases
ATGTGTATAGCAATTCCTGGTAAAATGACGGCTATTGTGGATGAAAATACAGCAACTATTGACATGGGCGGGATCTGCAG
AGATGTAAATATGGCACTCATGGGAGGTGCAAAGGAGACTATGATTGGAAAGCATTTCCTTGTACATGTTGGATATGCGA
TATCTGAGATTTCGGAAGAAGAAAGTGAAGAAACCATGCGCCTTCTCAAGATTATGGCCGGTCTCGAAGAAATTGACTCC
CTTGAAAGTGAATCTCAGTGA

Upstream 100 bases:

>100_bases
ATGAAAACAGCTTATTTAAAATAGCTCTTACACAAAAACTAATCTTATAATCATTGATACTAAAAACGACTATATTCTAA
AAGAAAACGGAAGAGGTAAC

Downstream 100 bases:

>100_bases
AAGTGGACGCTGATAATATGGAAAACGGAAAATCTCTTTCAAAAACAGCGGTTTCAGACATAGAAAAGAAACTCCTTGAA
AGGATTAAAGGTTCTGAGGT

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 86; Mature: 86

Protein sequence:

>86_residues
MCIAIPGKMTAIVDENTATIDMGGICRDVNMALMGGAKETMIGKHFLVHVGYAISEISEEESEETMRLLKIMAGLEEIDS
LESESQ

Sequences:

>Translated_86_residues
MCIAIPGKMTAIVDENTATIDMGGICRDVNMALMGGAKETMIGKHFLVHVGYAISEISEEESEETMRLLKIMAGLEEIDS
LESESQ
>Mature_86_residues
MCIAIPGKMTAIVDENTATIDMGGICRDVNMALMGGAKETMIGKHFLVHVGYAISEISEEESEETMRLLKIMAGLEEIDS
LESESQ

Specific function: Is Required For The Formation Of All Three Hydrogenase Isoenzymes. May Bind To The Precursor Form Of The Large Subunit Of Dehydrogenases To Keep Them In A Conformation Accessible For Metal Incorporation. [C]

COG id: COG0298

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hupF/hypC family [H]

Homologues:

Organism=Escherichia coli, GI1789083, Length=79, Percent_Identity=41.7721518987342, Blast_Score=63, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019812
- InterPro:   IPR001109 [H]

Pfam domain/function: PF01455 HupF_HypC [H]

EC number: NA

Molecular weight: Translated: 9336; Mature: 9336

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
9.3 %Met     (Translated Protein)
11.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
9.3 %Met     (Mature Protein)
11.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCIAIPGKMTAIVDENTATIDMGGICRDVNMALMGGAKETMIGKHFLVHVGYAISEISEE
CEEECCCCEEEEECCCCCEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ESEETMRLLKIMAGLEEIDSLESESQ
HHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MCIAIPGKMTAIVDENTATIDMGGICRDVNMALMGGAKETMIGKHFLVHVGYAISEISEE
CEEECCCCEEEEECCCCCEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ESEETMRLLKIMAGLEEIDSLESESQ
HHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3308458 [H]