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The map label for this gene is ubiE [H]

Identifier: 21228410

GI number: 21228410

Start: 2763886

End: 2764494

Strand: Direct

Name: ubiE [H]

Synonym: MM_2308

Alternate gene names: 21228410

Gene position: 2763886-2764494 (Clockwise)

Preceding gene: 21228406

Following gene: 21228412

Centisome position: 67.47

GC content: 44.17

Gene sequence:

>609_bases
ATGTTCACAATGTCCGCAGCCTCAAAATACAACCGGATAGCGCCCGTTTATGAACTGCTAGACCTGCCACTTGAATTTTT
CTTTTTCCGGAAATGGAGAAAAGAAGCACTTTCAGGCCTTAGCGGAAAAGTTCTGGAAATCGGGGTAGGAAGCGGAAGGA
ACCTGAAATACTATCCAGCAGGCTGTTCTGTAACGGGAATCGATGCCAGTGAGGGTATGCTCGAAAAAGCCAGGCAGAAA
ACCGGGGGAGTGAAAAACGTCAATCTTCTTCTGATGGACGCAGAACATCTTGAATTTCCGGACAAGAGCTTTGATTATGT
AATTGCGACTTTTGTCCTCTGCACAATCCCTGATCCTGTAATAGCTCTTAAAGAAATGAGGCGTGTCCTTAAACCTTCAG
GTGAACTTATAGCCCTTGAGCACATGCACAGCAGTAACTCAATTATTTCTCTTTTTGAGCACATGATCGATCCTTTTCTG
TTTTTCCTGCTTGGGGACCATACCACACGGCAGACGGTTAAAAATATACAGAAGGCGGGCTTTACCATTCTGGAGGCAAA
AAAACTGGCTTTTAAGGATATTTTCCGAAAAATCAGGGCAAAACCGTAA

Upstream 100 bases:

>100_bases
TTCAAATACTTAAATATGAATCGGTTTTCGGGAGTTTTCCGGGTAAAACCGTAAAAGGTTTAATTCTGAGCACTTTGTTA
TAATATCCACACCCTTAAAG

Downstream 100 bases:

>100_bases
AAGGCTTTTCTTTTTACGTTATATTTTTATAATGTTTACTTTTATCTGCTTTTAGCATGTCCTTTTTTCACTTTAAAACA
CTATTAAAATGAACCCTGTA

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MFTMSAASKYNRIAPVYELLDLPLEFFFFRKWRKEALSGLSGKVLEIGVGSGRNLKYYPAGCSVTGIDASEGMLEKARQK
TGGVKNVNLLLMDAEHLEFPDKSFDYVIATFVLCTIPDPVIALKEMRRVLKPSGELIALEHMHSSNSIISLFEHMIDPFL
FFLLGDHTTRQTVKNIQKAGFTILEAKKLAFKDIFRKIRAKP

Sequences:

>Translated_202_residues
MFTMSAASKYNRIAPVYELLDLPLEFFFFRKWRKEALSGLSGKVLEIGVGSGRNLKYYPAGCSVTGIDASEGMLEKARQK
TGGVKNVNLLLMDAEHLEFPDKSFDYVIATFVLCTIPDPVIALKEMRRVLKPSGELIALEHMHSSNSIISLFEHMIDPFL
FFLLGDHTTRQTVKNIQKAGFTILEAKKLAFKDIFRKIRAKP
>Mature_202_residues
MFTMSAASKYNRIAPVYELLDLPLEFFFFRKWRKEALSGLSGKVLEIGVGSGRNLKYYPAGCSVTGIDASEGMLEKARQK
TGGVKNVNLLLMDAEHLEFPDKSFDYVIATFVLCTIPDPVIALKEMRRVLKPSGELIALEHMHSSNSIISLFEHMIDPFL
FFLLGDHTTRQTVKNIQKAGFTILEAKKLAFKDIFRKIRAKP

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Homo sapiens, GI164663805, Length=163, Percent_Identity=32.5153374233129, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI89145417, Length=163, Percent_Identity=31.9018404907975, Blast_Score=87, Evalue=9e-18,
Organism=Escherichia coli, GI48994983, Length=169, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320522, Length=160, Percent_Identity=31.25, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.-

Molecular weight: Translated: 22805; Mature: 22805

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTMSAASKYNRIAPVYELLDLPLEFFFFRKWRKEALSGLSGKVLEIGVGSGRNLKYYPA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECC
GCSVTGIDASEGMLEKARQKTGGVKNVNLLLMDAEHLEFPDKSFDYVIATFVLCTIPDPV
CCEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCCCHHHHHHHHHHHCCCCHH
IALKEMRRVLKPSGELIALEHMHSSNSIISLFEHMIDPFLFFLLGDHTTRQTVKNIQKAG
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
FTILEAKKLAFKDIFRKIRAKP
CHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFTMSAASKYNRIAPVYELLDLPLEFFFFRKWRKEALSGLSGKVLEIGVGSGRNLKYYPA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECC
GCSVTGIDASEGMLEKARQKTGGVKNVNLLLMDAEHLEFPDKSFDYVIATFVLCTIPDPV
CCEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCCCHHHHHHHHHHHCCCCHH
IALKEMRRVLKPSGELIALEHMHSSNSIISLFEHMIDPFLFFLLGDHTTRQTVKNIQKAG
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
FTILEAKKLAFKDIFRKIRAKP
CHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA