| Definition | Methanosarcina mazei Go1 chromosome, complete genome. |
|---|---|
| Accession | NC_003901 |
| Length | 4,096,345 |
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The map label for this gene is hsdM [H]
Identifier: 21228396
GI number: 21228396
Start: 2736501
End: 2738927
Strand: Reverse
Name: hsdM [H]
Synonym: MM_2294
Alternate gene names: 21228396
Gene position: 2738927-2736501 (Counterclockwise)
Preceding gene: 21228398
Following gene: 21228395
Centisome position: 66.86
GC content: 49.48
Gene sequence:
>2427_bases ATGGCTCTAAAAAAATCCGAACTTTACTCTTCTCTCTGGTCCAGCTGCGATGAATTGCGCGGTGGAATGGATGCCAGCCA GTACAAGGACTATGTACTTGTCCTGTTGTTTATCAAATACGTCAGCGACAAATACGCTGACATTCCTTTTGCACCTATCA ATGTCCCTGAGGGTGCAAGCTTCAAGGATATGGTCGCACTCAAAGGCAAACCTGATATCGGCGATCAGATCAACAAAAAA ATAATCGCCCCACTGGTCAATGCCAACAAGCTGTCTGACATGCCGGACTTCAACGACTCTGCCAAGCTCGGCAGCGGTAA GGAACAGGTGGAAAGGCTTACTAACCTTATTGCCATTTTCGAGAATCCTGCCCTTGATTTCTCAAAGAACCGTGCCGAAG GCGACGATATCCTGGGCGATGCCTACGAATACCTGATGCGTCACTTCGCAACGGAAAGTGGAAAAAGCAAAGGCCAGTTC TATACTCCTGCCGAAGTCAGCCGAATTATAGCACAGATACTCGGAATCCGCTATGCCGATACCACAAGCTCCACAACAGC CTATGATCCAACATGCGGCTCCGGTTCACTTCTTTTGAAAGTTGCAGACGAGGCAAGGACCAAGATAACCCTGTACGGCC AGGAAAAAGATGCAACCACTTCCGGTCTTGCCCGCATGAACATGATCCTGCACAACAACCCCGAAGCTCTTATCGTGCAG GGAAACACCCTGACAGACCCCAGGTTCAAGGACAGGGAGACGCTCAAGACCTTTGATTACGTCGTTGCCAATCCACCTTT CAGTGACAAGCGGTGGAGCACAGGACTGGACCCGCTTAAAGATATTTACGAACGTTTTAAGCCATTTGGAATCCCACCTG CCAAGCAGGGAGATTACGCTTATCTGTTACATATCGTTCGTTCACTCAAGAGCACGGGCAAAGGGGCATGTATTCTGCCG CACGGTGTTCTGTTCCGTGGCAATTCCGAAGCCGAGATCCGCCATGCTCTCGTGCGCAAAGGCTACATTAAGGGTATCAT CGGCCTGCCAGCCAACCTTTTCTACGGCACAGGCATCCCTGCATGTATTATTGTTATTGATAAGGAAGAGGCTCAAAACC GTAAGAGCATTTTTATGATCGATGCCAGTGCGGGTTTCATGAAGGACGGCCCCAAGAACCGACTGCGTGCCCAGGATATC CACAGGATAGTGGACGTTTTCACAAGGCAGGCAGAGATCCCGAAATACTCGCGGATTGTCAGCTTTGAGGAAATCGAGAA GAACGAGTTCAACCTCAACCTTCCACGCTACATTGACAGCCAGCAGGATGAAGACCTTCAGGATATAGAAGGACACCTGC ATGGAGGAATCCCATGTGCAGATATTGATGCCCTCCAGAGTTACTGGAATATCTGTCCGCAGCTTCGACAGACCCTGTTT AAAGAGAAGCGCCCCGGCTATCTGGAGCTTGCCGTGGACAAGTCAGCTATCAAATCCACCATCTACGAGCACCCGGAGTT TGCAGCTTTTATCGCTGACATGAATGCACATTTCGCTGCCTGGCGTACAAAAACTTCTGATGTGCTCAGGCAGTTAGAGC CCGGCTGCCACCCGAAGGAAATCATAGACGAGCTTTCCGAAAACCTGCTCGCTCATTATGCAGATAAGCCGCTCATCAGC CAGTATGATATTTATCAGCACCTTATGGACTACTGGGCTGAGACTATGCAGGATGACTGCTACCTGATAGCGGATGAGGG CTGGAAGGCTGATACTTACCGCATTACCGAGAAGGACAAGAAGGGAAAAGAGAAAGACAAGGGCTGGATCTGCGACCTTG TGCCAAAGCCGCTTATCGTTTCCCGCTACTTCGCCAAAGAGCAGGAAGCTATCGATAAACTCACTGCTGAGCTGGAAAGT ATTACTGCCAGCATGACAGAGCTGGAAGAAGAACATGGAGGAGAAGAAGGCGCTTTTTCCGAACTTGAAAAGGTTAATAA GGCAAATGTCGCTGCACGCCTGAAAGATATAAAAAATGTCGCTGCACGCCTGAAAGATATAAAAAGCGATAGGGAAGCAA AAGAAGAAGCTGCTGTCCTCAATGACTGGCTGAGACTTGCCAATGAGGAGGCAAACCTCAAGAAGCGCCTGAAGGATGCT GAGACTTTACTCGATTCAAAAGCCTACCACTATTATCCAAAGCTTACTGAGGACGATGTCAAAACGCTGGTTGTGGAAGA TAAATGGCTTTCTTCACTGGATATAGCCATTCATGGAGAAATGGACCGGATCAGCCAGTCCCTTACCCAGCGCGTGAAAG AGCTCGCCGAACGCTACGAAATCCCGATGCCGCAGATGACTGACCGCGTGGCTGAACTGGAAGCAAAAGTGAACCGACAC TTGGAGAGGATGGGGTTTAGGCTATGA
Upstream 100 bases:
>100_bases CCGAACTACTTGAAATTCGTTAACAACATTTTCAATCTGCAAAGGTTCTATTTCGTGTTCAGCCGATCATCCCGGAGTAA GTATTCATTGGTGGTATGAA
Downstream 100 bases:
>100_bases GCGCGGAAGGCATCGCCGAAAATATCCCACCTGGCTACAAACAGACGGAGGTGGGGGTGATACCGGAGGATTGGAATGAT CCAAAACTCGAAGATATTGT
Product: type I restriction-modification system specificity subunit
Products: NA
Alternate protein names: M.EcoR124II [H]
Number of amino acids: Translated: 808; Mature: 807
Protein sequence:
>808_residues MALKKSELYSSLWSSCDELRGGMDASQYKDYVLVLLFIKYVSDKYADIPFAPINVPEGASFKDMVALKGKPDIGDQINKK IIAPLVNANKLSDMPDFNDSAKLGSGKEQVERLTNLIAIFENPALDFSKNRAEGDDILGDAYEYLMRHFATESGKSKGQF YTPAEVSRIIAQILGIRYADTTSSTTAYDPTCGSGSLLLKVADEARTKITLYGQEKDATTSGLARMNMILHNNPEALIVQ GNTLTDPRFKDRETLKTFDYVVANPPFSDKRWSTGLDPLKDIYERFKPFGIPPAKQGDYAYLLHIVRSLKSTGKGACILP HGVLFRGNSEAEIRHALVRKGYIKGIIGLPANLFYGTGIPACIIVIDKEEAQNRKSIFMIDASAGFMKDGPKNRLRAQDI HRIVDVFTRQAEIPKYSRIVSFEEIEKNEFNLNLPRYIDSQQDEDLQDIEGHLHGGIPCADIDALQSYWNICPQLRQTLF KEKRPGYLELAVDKSAIKSTIYEHPEFAAFIADMNAHFAAWRTKTSDVLRQLEPGCHPKEIIDELSENLLAHYADKPLIS QYDIYQHLMDYWAETMQDDCYLIADEGWKADTYRITEKDKKGKEKDKGWICDLVPKPLIVSRYFAKEQEAIDKLTAELES ITASMTELEEEHGGEEGAFSELEKVNKANVAARLKDIKNVAARLKDIKSDREAKEEAAVLNDWLRLANEEANLKKRLKDA ETLLDSKAYHYYPKLTEDDVKTLVVEDKWLSSLDIAIHGEMDRISQSLTQRVKELAERYEIPMPQMTDRVAELEAKVNRH LERMGFRL
Sequences:
>Translated_808_residues MALKKSELYSSLWSSCDELRGGMDASQYKDYVLVLLFIKYVSDKYADIPFAPINVPEGASFKDMVALKGKPDIGDQINKK IIAPLVNANKLSDMPDFNDSAKLGSGKEQVERLTNLIAIFENPALDFSKNRAEGDDILGDAYEYLMRHFATESGKSKGQF YTPAEVSRIIAQILGIRYADTTSSTTAYDPTCGSGSLLLKVADEARTKITLYGQEKDATTSGLARMNMILHNNPEALIVQ GNTLTDPRFKDRETLKTFDYVVANPPFSDKRWSTGLDPLKDIYERFKPFGIPPAKQGDYAYLLHIVRSLKSTGKGACILP HGVLFRGNSEAEIRHALVRKGYIKGIIGLPANLFYGTGIPACIIVIDKEEAQNRKSIFMIDASAGFMKDGPKNRLRAQDI HRIVDVFTRQAEIPKYSRIVSFEEIEKNEFNLNLPRYIDSQQDEDLQDIEGHLHGGIPCADIDALQSYWNICPQLRQTLF KEKRPGYLELAVDKSAIKSTIYEHPEFAAFIADMNAHFAAWRTKTSDVLRQLEPGCHPKEIIDELSENLLAHYADKPLIS QYDIYQHLMDYWAETMQDDCYLIADEGWKADTYRITEKDKKGKEKDKGWICDLVPKPLIVSRYFAKEQEAIDKLTAELES ITASMTELEEEHGGEEGAFSELEKVNKANVAARLKDIKNVAARLKDIKSDREAKEEAAVLNDWLRLANEEANLKKRLKDA ETLLDSKAYHYYPKLTEDDVKTLVVEDKWLSSLDIAIHGEMDRISQSLTQRVKELAERYEIPMPQMTDRVAELEAKVNRH LERMGFRL >Mature_807_residues ALKKSELYSSLWSSCDELRGGMDASQYKDYVLVLLFIKYVSDKYADIPFAPINVPEGASFKDMVALKGKPDIGDQINKKI IAPLVNANKLSDMPDFNDSAKLGSGKEQVERLTNLIAIFENPALDFSKNRAEGDDILGDAYEYLMRHFATESGKSKGQFY TPAEVSRIIAQILGIRYADTTSSTTAYDPTCGSGSLLLKVADEARTKITLYGQEKDATTSGLARMNMILHNNPEALIVQG NTLTDPRFKDRETLKTFDYVVANPPFSDKRWSTGLDPLKDIYERFKPFGIPPAKQGDYAYLLHIVRSLKSTGKGACILPH GVLFRGNSEAEIRHALVRKGYIKGIIGLPANLFYGTGIPACIIVIDKEEAQNRKSIFMIDASAGFMKDGPKNRLRAQDIH RIVDVFTRQAEIPKYSRIVSFEEIEKNEFNLNLPRYIDSQQDEDLQDIEGHLHGGIPCADIDALQSYWNICPQLRQTLFK EKRPGYLELAVDKSAIKSTIYEHPEFAAFIADMNAHFAAWRTKTSDVLRQLEPGCHPKEIIDELSENLLAHYADKPLISQ YDIYQHLMDYWAETMQDDCYLIADEGWKADTYRITEKDKKGKEKDKGWICDLVPKPLIVSRYFAKEQEAIDKLTAELESI TASMTELEEEHGGEEGAFSELEKVNKANVAARLKDIKNVAARLKDIKSDREAKEEAAVLNDWLRLANEEANLKKRLKDAE TLLDSKAYHYYPKLTEDDVKTLVVEDKWLSSLDIAIHGEMDRISQSLTQRVKELAERYEIPMPQMTDRVAELEAKVNRHL ERMGFRL
Specific function: Methylation of specific adenine residues; required for both restriction and modification activities. The EcoR124/3 I enzyme recognizes 5'-GAAN(7)RTCG-3' [H]
COG id: COG0286
COG function: function code V; Type I restriction-modification system methyltransferase subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]
Homologues:
Organism=Escherichia coli, GI1790808, Length=396, Percent_Identity=24.7474747474747, Blast_Score=106, Evalue=5e-24,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR022749 - InterPro: IPR003356 - InterPro: IPR002052 - InterPro: IPR002296 - InterPro: IPR004546 [H]
Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]
EC number: =2.1.1.72 [H]
Molecular weight: Translated: 91506; Mature: 91375
Theoretical pI: Translated: 5.46; Mature: 5.46
Prosite motif: PS00092 N6_MTASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MALKKSELYSSLWSSCDELRGGMDASQYKDYVLVLLFIKYVSDKYADIPFAPINVPEGAS CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC FKDMVALKGKPDIGDQINKKIIAPLVNANKLSDMPDFNDSAKLGSGKEQVERLTNLIAIF HHHHEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH ENPALDFSKNRAEGDDILGDAYEYLMRHFATESGKSKGQFYTPAEVSRIIAQILGIRYAD CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEECC TTSSTTAYDPTCGSGSLLLKVADEARTKITLYGQEKDATTSGLARMNMILHNNPEALIVQ CCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHEECCCCEEEEE GNTLTDPRFKDRETLKTFDYVVANPPFSDKRWSTGLDPLKDIYERFKPFGIPPAKQGDYA CCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHH YLLHIVRSLKSTGKGACILPHGVLFRGNSEAEIRHALVRKGYIKGIIGLPANLFYGTGIP HHHHHHHHHHHCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCC ACIIVIDKEEAQNRKSIFMIDASAGFMKDGPKNRLRAQDIHRIVDVFTRQAEIPKYSRIV EEEEEEECHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHC SFEEIEKNEFNLNLPRYIDSQQDEDLQDIEGHLHGGIPCADIDALQSYWNICPQLRQTLF CHHHHCCCCCCCCCCHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH KEKRPGYLELAVDKSAIKSTIYEHPEFAAFIADMNAHFAAWRTKTSDVLRQLEPGCHPKE HHCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHCCCHHHHHHCHHHHHHHHHCCCCCHHH IIDELSENLLAHYADKPLISQYDIYQHLMDYWAETMQDDCYLIADEGWKADTYRITEKDK HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCC KGKEKDKGWICDLVPKPLIVSRYFAKEQEAIDKLTAELESITASMTELEEEHGGEEGAFS CCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH ELEKVNKANVAARLKDIKNVAARLKDIKSDREAKEEAAVLNDWLRLANEEANLKKRLKDA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH ETLLDSKAYHYYPKLTEDDVKTLVVEDKWLSSLDIAIHGEMDRISQSLTQRVKELAERYE HHHHHCCCCEECCCCCCCCHHEEEECCHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHC IPMPQMTDRVAELEAKVNRHLERMGFRL CCCHHHHHHHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure ALKKSELYSSLWSSCDELRGGMDASQYKDYVLVLLFIKYVSDKYADIPFAPINVPEGAS CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC FKDMVALKGKPDIGDQINKKIIAPLVNANKLSDMPDFNDSAKLGSGKEQVERLTNLIAIF HHHHEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH ENPALDFSKNRAEGDDILGDAYEYLMRHFATESGKSKGQFYTPAEVSRIIAQILGIRYAD CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEECC TTSSTTAYDPTCGSGSLLLKVADEARTKITLYGQEKDATTSGLARMNMILHNNPEALIVQ CCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHEECCCCEEEEE GNTLTDPRFKDRETLKTFDYVVANPPFSDKRWSTGLDPLKDIYERFKPFGIPPAKQGDYA CCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHH YLLHIVRSLKSTGKGACILPHGVLFRGNSEAEIRHALVRKGYIKGIIGLPANLFYGTGIP HHHHHHHHHHHCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCC ACIIVIDKEEAQNRKSIFMIDASAGFMKDGPKNRLRAQDIHRIVDVFTRQAEIPKYSRIV EEEEEEECHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHC SFEEIEKNEFNLNLPRYIDSQQDEDLQDIEGHLHGGIPCADIDALQSYWNICPQLRQTLF CHHHHCCCCCCCCCCHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH KEKRPGYLELAVDKSAIKSTIYEHPEFAAFIADMNAHFAAWRTKTSDVLRQLEPGCHPKE HHCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHCCCHHHHHHCHHHHHHHHHCCCCCHHH IIDELSENLLAHYADKPLISQYDIYQHLMDYWAETMQDDCYLIADEGWKADTYRITEKDK HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCC KGKEKDKGWICDLVPKPLIVSRYFAKEQEAIDKLTAELESITASMTELEEEHGGEEGAFS CCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH ELEKVNKANVAARLKDIKNVAARLKDIKSDREAKEEAAVLNDWLRLANEEANLKKRLKDA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH ETLLDSKAYHYYPKLTEDDVKTLVVEDKWLSSLDIAIHGEMDRISQSLTQRVKELAERYE HHHHHCCCCEECCCCCCCCHHEEEECCHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHC IPMPQMTDRVAELEAKVNRHLERMGFRL CCCHHHHHHHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2784505 [H]