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The map label for this gene is 21228383

Identifier: 21228383

GI number: 21228383

Start: 2720047

End: 2720808

Strand: Reverse

Name: 21228383

Synonym: MM_2281

Alternate gene names: NA

Gene position: 2720808-2720047 (Counterclockwise)

Preceding gene: 21228384

Following gene: 21228382

Centisome position: 66.42

GC content: 49.34

Gene sequence:

>762_bases
ATGACAGATATACCGCACGACCACCCGAGGTACGAATCCCTGCTCGCCCGTGAAAAAGTTGCAGCAGGGGTAAAAATGGG
AATTACAAGTATCCAGGGACTTATTGCCCAGGGTAGAGGCGAGAGTTTTGATTACCTTATTGGTGAAAGAAGCACAGAGT
CCGCCCTGTATGCAGAGAGGGCTGCAGTTGCTGCGCTTCTCCTCGCTGAGAATCCGGTAATTTCAGTAAATGGTAATGTT
GCAGCCCTGGCACCTGATAAAGTAGTTACCCTTGCAGATATCACCGGAGCCAGGATTGAAGTAAACCTTTTCCACAGGAC
TGACACACGGGTACATCTCATAATAGAACAGCTGAAAGCAAGCGGGGCTGCTGAGGTGCTTGGAAAGAACCCGGATGCGA
GCCTTGAACTCTCACACGACAGAAGGCTTGTGAGCAGCAAAGGGATCTATACCGCAGATGTCGTGCTCGTCCCCCTGGAA
GACGGAGACCGCTGCGAGAAGCTTGTAGAGATGGGAAAGACTGTGATAACAATCGACCTGAACCCTCTTTCACGGACCTC
GAAAACAGCCACGATATCTATTGTTGACAACCTTACGCGAGCCCTTGGAAATATGGCAAAATTCGCGCAGGAAATGAAAA
AGGAAAGGAAAGAAGAGCTTGTGAAGCTGATAACCACCTATGATAATAAAAGGACCCTTTCCGAAGCGATTTCCGAAATC
CAGGAACACCTCAAGACCATGGCCGCAGAAACAGGGTACTGA

Upstream 100 bases:

>100_bases
AGTACTGAACCGCATAAAATGCCCTTAGATCAGGGCAAAGCCCTTAAAATTCCAGATAGCAGGAATGAAAGTAACACAAG
TATAAAGGTAAGCGACCTAC

Downstream 100 bases:

>100_bases
AAGCCAATAATTATCCAGAAAAGGCAACATATGAACCTTATAGAAAAAACGAGGGAATTTGCAGCTACTTTTCATGAAGG
AGAGCCCAGTTCCCACGATA

Product: hypothetical protein

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTDIPHDHPRYESLLAREKVAAGVKMGITSIQGLIAQGRGESFDYLIGERSTESALYAERAAVAALLLAENPVISVNGNV
AALAPDKVVTLADITGARIEVNLFHRTDTRVHLIIEQLKASGAAEVLGKNPDASLELSHDRRLVSSKGIYTADVVLVPLE
DGDRCEKLVEMGKTVITIDLNPLSRTSKTATISIVDNLTRALGNMAKFAQEMKKERKEELVKLITTYDNKRTLSEAISEI
QEHLKTMAAETGY

Sequences:

>Translated_253_residues
MTDIPHDHPRYESLLAREKVAAGVKMGITSIQGLIAQGRGESFDYLIGERSTESALYAERAAVAALLLAENPVISVNGNV
AALAPDKVVTLADITGARIEVNLFHRTDTRVHLIIEQLKASGAAEVLGKNPDASLELSHDRRLVSSKGIYTADVVLVPLE
DGDRCEKLVEMGKTVITIDLNPLSRTSKTATISIVDNLTRALGNMAKFAQEMKKERKEELVKLITTYDNKRTLSEAISEI
QEHLKTMAAETGY
>Mature_252_residues
TDIPHDHPRYESLLAREKVAAGVKMGITSIQGLIAQGRGESFDYLIGERSTESALYAERAAVAALLLAENPVISVNGNVA
ALAPDKVVTLADITGARIEVNLFHRTDTRVHLIIEQLKASGAAEVLGKNPDASLELSHDRRLVSSKGIYTADVVLVPLED
GDRCEKLVEMGKTVITIDLNPLSRTSKTATISIVDNLTRALGNMAKFAQEMKKERKEELVKLITTYDNKRTLSEAISEIQ
EHLKTMAAETGY

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent and ADP-producing reaction

COG id: COG1701

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal pantothenate synthetase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PASYA_METMA (Q8PUQ1)

Other databases:

- EMBL:   AE008384
- RefSeq:   NP_634305.1
- GeneID:   1480623
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_2281
- NMPDR:   fig|192952.1.peg.2281
- HOGENOM:   HBG297347
- OMA:   GEAFDYL
- ProtClustDB:   PRK13761
- BioCyc:   MMAZ192952:MM2281-MONOMER
- InterPro:   IPR002855
- PIRSF:   PIRSF004853
- ProDom:   PD016827

Pfam domain/function: PF02006 DUF137

EC number: NA

Molecular weight: Translated: 27594; Mature: 27463

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIPHDHPRYESLLAREKVAAGVKMGITSIQGLIAQGRGESFDYLIGERSTESALYAER
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHH
AAVAALLLAENPVISVNGNVAALAPDKVVTLADITGARIEVNLFHRTDTRVHLIIEQLKA
HHHHHHHHCCCCEEEECCCEEEECCCCEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHC
SGAAEVLGKNPDASLELSHDRRLVSSKGIYTADVVLVPLEDGDRCEKLVEMGKTVITIDL
CCHHHHHCCCCCCCEEECCCHHHHHCCCCEEEEEEEEECCCCHHHHHHHHCCCEEEEEEC
NPLSRTSKTATISIVDNLTRALGNMAKFAQEMKKERKEELVKLITTYDNKRTLSEAISEI
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QEHLKTMAAETGY
HHHHHHHHHCCCC
>Mature Secondary Structure 
TDIPHDHPRYESLLAREKVAAGVKMGITSIQGLIAQGRGESFDYLIGERSTESALYAER
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHH
AAVAALLLAENPVISVNGNVAALAPDKVVTLADITGARIEVNLFHRTDTRVHLIIEQLKA
HHHHHHHHCCCCEEEECCCEEEECCCCEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHC
SGAAEVLGKNPDASLELSHDRRLVSSKGIYTADVVLVPLEDGDRCEKLVEMGKTVITIDL
CCHHHHHCCCCCCCEEECCCHHHHHCCCCEEEEEEEEECCCCHHHHHHHHCCCEEEEEEC
NPLSRTSKTATISIVDNLTRALGNMAKFAQEMKKERKEELVKLITTYDNKRTLSEAISEI
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QEHLKTMAAETGY
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824