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The map label for this gene is cadC [H]

Identifier: 21228349

GI number: 21228349

Start: 2675235

End: 2675546

Strand: Direct

Name: cadC [H]

Synonym: MM_2247

Alternate gene names: 21228349

Gene position: 2675235-2675546 (Clockwise)

Preceding gene: 21228346

Following gene: 21228350

Centisome position: 65.31

GC content: 33.65

Gene sequence:

>312_bases
ATGTATCTTGATATGATTAATGAAAAAAACTTACAAATTTTCAAGGCTCTTAGCGAAGATACAAGGTATAGAATCATCAA
GGCTCTAATTGAATCTGAGTGCAAATGTGGGGAAAATAAACACGGTAATAAAGGTGAAATATGCGCATGTGAAATTCCAG
AAATTATTGGTAAGACTCAATCCAATACCTCAATGCACCTTGCAAAACTACAGGACTGGGGGATAATTAAAGTAAGAAAA
GAAGGCAAAAAGAGATTATATTCCATACAAAACGAAAAAATCAGGAAAATCCTGGAAGTCCTTGAAGAGTAA

Upstream 100 bases:

>100_bases
GATAAGGATTAATAAGCAATTAAGACCGTTGAAATTCATCAGGATAATTCAATTCAGTATTAATTCCTGGCTTTAGAAAA
GTATATATCTTTCACATTCA

Downstream 100 bases:

>100_bases
TGTTTAGTATTATTATAGAAACTTTTAGTACTATTATAGAAACCTTATGAGCTGTGTTCCCTGAAAGTTATGAGTGGATT
AAAGTTTTTTTCAGGATCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 103; Mature: 103

Protein sequence:

>103_residues
MYLDMINEKNLQIFKALSEDTRYRIIKALIESECKCGENKHGNKGEICACEIPEIIGKTQSNTSMHLAKLQDWGIIKVRK
EGKKRLYSIQNEKIRKILEVLEE

Sequences:

>Translated_103_residues
MYLDMINEKNLQIFKALSEDTRYRIIKALIESECKCGENKHGNKGEICACEIPEIIGKTQSNTSMHLAKLQDWGIIKVRK
EGKKRLYSIQNEKIRKILEVLEE
>Mature_103_residues
MYLDMINEKNLQIFKALSEDTRYRIIKALIESECKCGENKHGNKGEICACEIPEIIGKTQSNTSMHLAKLQDWGIIKVRK
EGKKRLYSIQNEKIRKILEVLEE

Specific function: Metal-binding repressor for the cad operon. Involved in resistance to heavy metals, such as cadmium, bismuth, zinc or lead. Metal binding causes the repressor to dissociate from the DNA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11981; Mature: 11981

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLDMINEKNLQIFKALSEDTRYRIIKALIESECKCGENKHGNKGEICACEIPEIIGKTQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHCCCC
SNTSMHLAKLQDWGIIKVRKEGKKRLYSIQNEKIRKILEVLEE
CCCCCHHEECCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHCC
>Mature Secondary Structure
MYLDMINEKNLQIFKALSEDTRYRIIKALIESECKCGENKHGNKGEICACEIPEIIGKTQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHCCCC
SNTSMHLAKLQDWGIIKVRKEGKKRLYSIQNEKIRKILEVLEE
CCCCCHHEECCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1321115 [H]