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The map label for this gene is arsC [H]

Identifier: 21228346

GI number: 21228346

Start: 2672430

End: 2672789

Strand: Direct

Name: arsC [H]

Synonym: MM_2244

Alternate gene names: 21228346

Gene position: 2672430-2672789 (Clockwise)

Preceding gene: 21228345

Following gene: 21228349

Centisome position: 65.24

GC content: 42.78

Gene sequence:

>360_bases
ATGGCTGAAGGTCTTTTGAGGAATATTTATGGAAGTCGATACGAGGCTTACAGCGCCGGTATTATGGCCACAAATGTTAA
TCCGTATGCTGTTCGAGTTATGAAGGAAATTGGCATTGACATCTCCAGTCAATACTCCAAAACTCATAAAGAATTCCAGG
ATGTCATTTTTGACATGGCAGTCACAGTATGTGATCGGGCTAAAGTTTCCTGTCCTATCTGCAGTACAAACCTGGAAGTT
CCAGTCGAATACCCAAAAGCAAGAGAGGTGATTCACAAAAGTTTTGAGGATCCCGCTGCAACTTTGGGATCAGAAGACGA
GAAGCTTAAGGTCTTCCGCCAGATCAGAGATGAGATATAA

Upstream 100 bases:

>100_bases
TAATTATTATATGCAATAACAGTCATATGGTGCCAAATACGGGATCAAAAGAAAAAAGAAAGTTCTTTTTTTACGCACCC
ACAACTCAGCCAGATCCCGG

Downstream 100 bases:

>100_bases
GACTGGATCATCCGGATATTTGGGAAATGATCCAGGTCTTTGATCTACATGCTTGGTATGGTTTCTAAGCTTTTATAAGG
TTTTCACAATGTCAGCAGAT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MAEGLLRNIYGSRYEAYSAGIMATNVNPYAVRVMKEIGIDISSQYSKTHKEFQDVIFDMAVTVCDRAKVSCPICSTNLEV
PVEYPKAREVIHKSFEDPAATLGSEDEKLKVFRQIRDEI

Sequences:

>Translated_119_residues
MAEGLLRNIYGSRYEAYSAGIMATNVNPYAVRVMKEIGIDISSQYSKTHKEFQDVIFDMAVTVCDRAKVSCPICSTNLEV
PVEYPKAREVIHKSFEDPAATLGSEDEKLKVFRQIRDEI
>Mature_118_residues
AEGLLRNIYGSRYEAYSAGIMATNVNPYAVRVMKEIGIDISSQYSKTHKEFQDVIFDMAVTVCDRAKVSCPICSTNLEVP
VEYPKAREVIHKSFEDPAATLGSEDEKLKVFRQIRDEI

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 13438; Mature: 13307

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGLLRNIYGSRYEAYSAGIMATNVNPYAVRVMKEIGIDISSQYSKTHKEFQDVIFDMA
CCCHHHHHHHCCHHHHHHCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VTVCDRAKVSCPICSTNLEVPVEYPKAREVIHKSFEDPAATLGSEDEKLKVFRQIRDEI
HHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEGLLRNIYGSRYEAYSAGIMATNVNPYAVRVMKEIGIDISSQYSKTHKEFQDVIFDMA
CCHHHHHHHCCHHHHHHCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VTVCDRAKVSCPICSTNLEVPVEYPKAREVIHKSFEDPAATLGSEDEKLKVFRQIRDEI
HHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA