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The map label for this gene is moaC [H]

Identifier: 21228308

GI number: 21228308

Start: 2621265

End: 2621738

Strand: Reverse

Name: moaC [H]

Synonym: MM_2206

Alternate gene names: 21228308

Gene position: 2621738-2621265 (Counterclockwise)

Preceding gene: 21228309

Following gene: 21228307

Centisome position: 64.0

GC content: 47.05

Gene sequence:

>474_bases
GTGGAGAAATCTTTTACTCATATTGAAGCCGGCAGGGCACGAATGGTCGATATAAGCGAAAAAAACGATGTTTCAAGACT
GGCAAGGGCTGCCGGAGAAATCGTGCTTTCTGCAGAGACGCTGGAGAAAATACGGACAGGAACCGTTGAAAAAGGAAATG
TTTTTGCAACTGCCAGGGTTGCAGCTGTCCTTGCAGTTAAAAAGACCCCCGAAACAATCCCAATGTGCCACCAGATCCCC
ATAACAGGGATAGATGTAGACTTTGAGATAGGGGAAGAAGCGGTTTCTGCTGTGGTCGAGGTCAGGACTGTCGGGAAGAC
GGGAGTTGAAATGGAGGCTCTGACAGGTGTCTCTTCTGCTCTGCTAACAGTCTGGGATATGGTAAAATCTGCGGAAAAAG
ACGAAATCGGCAACTATCCTCACACACTTATAAGAAATATCAGGGTGCTTGAGAAGCTAAAGGGTAAAGCTTGA

Upstream 100 bases:

>100_bases
TGAAATTGAATTGATATGAAATTGAATTGATATGAAATTGAATTGATATGAAATTGAAATTACATAGAGTTCCGGACAGT
AATAAAAACGCGGTGGTGTC

Downstream 100 bases:

>100_bases
AAAGATAAAAATGGCATTGAAAAGCTAGAGCCTGAAAAGCAGGGTCCATAAAAATAAGTTTTTTAAAGGATGGAATATAT
CAAGACGGCAACTGAGGTAT

Product: putative molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MEKSFTHIEAGRARMVDISEKNDVSRLARAAGEIVLSAETLEKIRTGTVEKGNVFATARVAAVLAVKKTPETIPMCHQIP
ITGIDVDFEIGEEAVSAVVEVRTVGKTGVEMEALTGVSSALLTVWDMVKSAEKDEIGNYPHTLIRNIRVLEKLKGKA

Sequences:

>Translated_157_residues
MEKSFTHIEAGRARMVDISEKNDVSRLARAAGEIVLSAETLEKIRTGTVEKGNVFATARVAAVLAVKKTPETIPMCHQIP
ITGIDVDFEIGEEAVSAVVEVRTVGKTGVEMEALTGVSSALLTVWDMVKSAEKDEIGNYPHTLIRNIRVLEKLKGKA
>Mature_157_residues
MEKSFTHIEAGRARMVDISEKNDVSRLARAAGEIVLSAETLEKIRTGTVEKGNVFATARVAAVLAVKKTPETIPMCHQIP
ITGIDVDFEIGEEAVSAVVEVRTVGKTGVEMEALTGVSSALLTVWDMVKSAEKDEIGNYPHTLIRNIRVLEKLKGKA

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=157, Percent_Identity=42.0382165605096, Blast_Score=110, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI32566331, Length=155, Percent_Identity=36.7741935483871, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28574490, Length=156, Percent_Identity=38.4615384615385, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=38.8888888888889, Blast_Score=97, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023047
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17002; Mature: 17002

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKSFTHIEAGRARMVDISEKNDVSRLARAAGEIVLSAETLEKIRTGTVEKGNVFATARV
CCCCCCHHHCCCEEEEECCCCCHHHHHHHHHHHEEECHHHHHHHHCCCCCCCCEEHHHHH
AAVLAVKKTPETIPMCHQIPITGIDVDFEIGEEAVSAVVEVRTVGKTGVEMEALTGVSSA
HHHHHHCCCCCCCCCHHCCCCCCCCCCHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LLTVWDMVKSAEKDEIGNYPHTLIRNIRVLEKLKGKA
HHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEKSFTHIEAGRARMVDISEKNDVSRLARAAGEIVLSAETLEKIRTGTVEKGNVFATARV
CCCCCCHHHCCCEEEEECCCCCHHHHHHHHHHHEEECHHHHHHHHCCCCCCCCEEHHHHH
AAVLAVKKTPETIPMCHQIPITGIDVDFEIGEEAVSAVVEVRTVGKTGVEMEALTGVSSA
HHHHHHCCCCCCCCCHHCCCCCCCCCCHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LLTVWDMVKSAEKDEIGNYPHTLIRNIRVLEKLKGKA
HHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]