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The map label for this gene is 21228301

Identifier: 21228301

GI number: 21228301

Start: 2612756

End: 2613910

Strand: Direct

Name: 21228301

Synonym: MM_2199

Alternate gene names: NA

Gene position: 2612756-2613910 (Clockwise)

Preceding gene: 21228300

Following gene: 21228302

Centisome position: 63.78

GC content: 39.65

Gene sequence:

>1155_bases
GTGACGGGGGAATGGAAGGAATGTAAGCTGAGGGAAATAGCGTCAGAAATAAAATCCGGTGGTACACCATCAACAAAGCA
TCAAGAATATTATGGAGGAATTATCCCTTGGCTCAACACAAAAGAAATTCACTTCAATAGAATTCGCGATACGGACATAA
AAATTACAGAAGGTGGGTTAAACAACTCCTCTGCAAAATGGGTTAAAGAAAATTCTATTATTGTTGCCATGTATGGTGCA
ACTGCTGGAAAAATAGCTATAAATAAAATTCCCTTAACTACAAATCAGGCGTGTTGCAATATTACGCCCGATAGCGAAAA
AGCAGACTATAACTTCGTATATTATAATTTATGTCATAGATACGATGAATTGGTAAATCTGAGTTGTGGTGCTGCTCAAC
AAAATCTAAATGTTGGGTTAATTACCAATCTTGATATTATTCTTCCCCCTATCACCGAACAATGCGCTATCGCCTCCGTT
CTTTCCAGCCTCGACGACAAGATAGACCTGCTCCACCGCCAGAACAAGACCCTTGAAGCTATGGCAGAAACGCTGTTCAG
GCAGTGGTTTGTGGAGGAGGCGGATGAGGATTGGGAGGAAGGTTTTCTTCCTGATGAATTTGATTTCACTATGGGTCAAT
CCCCTCCGGGCACTTCTTACAATCAAGAAGGTGTTGGGAAGCCAATGTTTCAAGGAAATGCTGATTTTGGTTTCAGATTT
CCAGAAGAGAGAGTTTATACTACCGAACCTACACGATTAGCATATCCGCATGATACTTTGATAAGTGTTAGAGCTCCTGT
GGGGGCACAAAACATGGCAAAAGTAGAGTGTTGTATTGGGCGTGGAGTTTCTGCTTTTCGCTATAAAGCTAACAATGATT
TTTACACATATACATATTTTAAGTTACGTTCATTGATGGATGAAATTAAAAAGTTCAATGATGAAGGGACTGTATTTGGT
TCGATTAGTAAAACAGACTTCCTGCAAATGGGAATTGCAATTCCTCCTGAAGACATAATAGAAAAGTTTGAAATCCATGC
AAAGCCGCTTAATGATAAAGTAATTGAGAATTGCATTCAAATAAAATTACTTGAGGTTATGAGAGATACGCTGCTGCCTA
AATTGATGAGTGGGGAAGTGAGGGTGGAGGGATGA

Upstream 100 bases:

>100_bases
ATTTCGGCGCTTCCCTGAAATACCTCGATAAGAAATGGTTCGCCTTCTCAAAAATGGATATAGGAGCAATTGAGATACTC
ACAAGGCTGGAGGGGATGAA

Downstream 100 bases:

>100_bases
GTAAACACACCGAAAGTATTCATATTTTGGATAAAGTAGGATTATACGTAACTTCGTTGTGGCTTCTATTTTTCCTGTTA
ATAGTACTAACAATTGATGT

Product: type I restriction-modification system specificity subunit

Products: NA

Alternate protein names: S.MjaXIP; Type I restriction enzyme MjaXIP specificity protein; S protein [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MTGEWKECKLREIASEIKSGGTPSTKHQEYYGGIIPWLNTKEIHFNRIRDTDIKITEGGLNNSSAKWVKENSIIVAMYGA
TAGKIAINKIPLTTNQACCNITPDSEKADYNFVYYNLCHRYDELVNLSCGAAQQNLNVGLITNLDIILPPITEQCAIASV
LSSLDDKIDLLHRQNKTLEAMAETLFRQWFVEEADEDWEEGFLPDEFDFTMGQSPPGTSYNQEGVGKPMFQGNADFGFRF
PEERVYTTEPTRLAYPHDTLISVRAPVGAQNMAKVECCIGRGVSAFRYKANNDFYTYTYFKLRSLMDEIKKFNDEGTVFG
SISKTDFLQMGIAIPPEDIIEKFEIHAKPLNDKVIENCIQIKLLEVMRDTLLPKLMSGEVRVEG

Sequences:

>Translated_384_residues
MTGEWKECKLREIASEIKSGGTPSTKHQEYYGGIIPWLNTKEIHFNRIRDTDIKITEGGLNNSSAKWVKENSIIVAMYGA
TAGKIAINKIPLTTNQACCNITPDSEKADYNFVYYNLCHRYDELVNLSCGAAQQNLNVGLITNLDIILPPITEQCAIASV
LSSLDDKIDLLHRQNKTLEAMAETLFRQWFVEEADEDWEEGFLPDEFDFTMGQSPPGTSYNQEGVGKPMFQGNADFGFRF
PEERVYTTEPTRLAYPHDTLISVRAPVGAQNMAKVECCIGRGVSAFRYKANNDFYTYTYFKLRSLMDEIKKFNDEGTVFG
SISKTDFLQMGIAIPPEDIIEKFEIHAKPLNDKVIENCIQIKLLEVMRDTLLPKLMSGEVRVEG
>Mature_383_residues
TGEWKECKLREIASEIKSGGTPSTKHQEYYGGIIPWLNTKEIHFNRIRDTDIKITEGGLNNSSAKWVKENSIIVAMYGAT
AGKIAINKIPLTTNQACCNITPDSEKADYNFVYYNLCHRYDELVNLSCGAAQQNLNVGLITNLDIILPPITEQCAIASVL
SSLDDKIDLLHRQNKTLEAMAETLFRQWFVEEADEDWEEGFLPDEFDFTMGQSPPGTSYNQEGVGKPMFQGNADFGFRFP
EERVYTTEPTRLAYPHDTLISVRAPVGAQNMAKVECCIGRGVSAFRYKANNDFYTYTYFKLRSLMDEIKKFNDEGTVFGS
ISKTDFLQMGIAIPPEDIIEKFEIHAKPLNDKVIENCIQIKLLEVMRDTLLPKLMSGEVRVEG

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 43383; Mature: 43252

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGEWKECKLREIASEIKSGGTPSTKHQEYYGGIIPWLNTKEIHFNRIRDTDIKITEGGL
CCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCEEEEECCC
NNSSAKWVKENSIIVAMYGATAGKIAINKIPLTTNQACCNITPDSEKADYNFVYYNLCHR
CCCCCCEEECCCEEEEEECCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCEEEHHHHHH
YDELVNLSCGAAQQNLNVGLITNLDIILPPITEQCAIASVLSSLDDKIDLLHRQNKTLEA
HHHHHCCCCCCCCCCCCEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
MAETLFRQWFVEEADEDWEEGFLPDEFDFTMGQSPPGTSYNQEGVGKPMFQGNADFGFRF
HHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PEERVYTTEPTRLAYPHDTLISVRAPVGAQNMAKVECCIGRGVSAFRYKANNDFYTYTYF
CCCCEEECCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEHHH
KLRSLMDEIKKFNDEGTVFGSISKTDFLQMGIAIPPEDIIEKFEIHAKPLNDKVIENCIQ
HHHHHHHHHHHCCCCCCEEECCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
IKLLEVMRDTLLPKLMSGEVRVEG
HHHHHHHHHHHHHHHHCCCEEECC
>Mature Secondary Structure 
TGEWKECKLREIASEIKSGGTPSTKHQEYYGGIIPWLNTKEIHFNRIRDTDIKITEGGL
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCEEEEECCC
NNSSAKWVKENSIIVAMYGATAGKIAINKIPLTTNQACCNITPDSEKADYNFVYYNLCHR
CCCCCCEEECCCEEEEEECCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCEEEHHHHHH
YDELVNLSCGAAQQNLNVGLITNLDIILPPITEQCAIASVLSSLDDKIDLLHRQNKTLEA
HHHHHCCCCCCCCCCCCEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
MAETLFRQWFVEEADEDWEEGFLPDEFDFTMGQSPPGTSYNQEGVGKPMFQGNADFGFRF
HHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PEERVYTTEPTRLAYPHDTLISVRAPVGAQNMAKVECCIGRGVSAFRYKANNDFYTYTYF
CCCCEEECCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEHHH
KLRSLMDEIKKFNDEGTVFGSISKTDFLQMGIAIPPEDIIEKFEIHAKPLNDKVIENCIQ
HHHHHHHHHHHCCCCCCEEECCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
IKLLEVMRDTLLPKLMSGEVRVEG
HHHHHHHHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]