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The map label for this gene is hsdM [C]

Identifier: 21228300

GI number: 21228300

Start: 2611111

End: 2612628

Strand: Direct

Name: hsdM [C]

Synonym: MM_2198

Alternate gene names: 21228300

Gene position: 2611111-2612628 (Clockwise)

Preceding gene: 21228296

Following gene: 21228301

Centisome position: 63.74

GC content: 47.69

Gene sequence:

>1518_bases
ATGAGTGATTTTGAAAAGCAATTGTGGAAAGCGGCAGACAAACTCCGAAAAAATATTGATGCTGCTGAGTATAAGCACAT
AGTTTTGGGCTTGATTTTTCTAAGATACATCTCAGATGCCTTTGAGGAATTATATGAAAAATTGCAACAGGGGGAAGGGG
AGTACGCCGGTGCAGACCCTGAAGACAGGGATGAATACAAAGCGGAGAATGTCTTTTTTGTCCCTGCAATTTCCCGCTGG
CCATATCTGCAATCAGAAGCCAAAAAACCGGATATCGGTAAATCTGTTGATAATGCAATGGATGCCATCGAAAAAGAGAA
TCCTCTGCTTAGAGGGGTTTTACCAAAGGTATTTGCACGGGGCAATCTTGACCCTACAAATCTTGGCGGTCTGATTGATC
TGGTGAGCAATGTTGCTCTTGGAGATGCCAAAAGCAGAAGTGCTGATGTTCTCGGTCATGTCTTCGAATATTTCCTTGGT
GAATTTGCTCTGGCAGAAGGAAAAAAGGGTGGACAGTTCTACACTCCGAGAAGCGTTGTTGAGTTACTGGTAGAGATGCT
GGAGCCCTACAATGGCCGGGTCTTTGACCCATGCTGCGGTTCCGGTGGCATGTTTGTGCAGTCAGAGAAGTTTGTTGCTG
ACCATCAGGGAAAAATAAACGATATATCGATCTACGGGCAGGAGAGCAATCAGACAACGTGGCGGTTGGCAAAGATGAAT
CTCGCCATCAGAAGCATTGACAGTTCCCAGGTTAAATGGAACAATGAAGGCTCTTTCCTCAATGATGTCCATAAAGACCT
GAAAGCGGATTATGTCATAGCCAATCCGCCGTTCAATGACAGCGACTGGAGTGGCGACCTGTTACGCAAGGACGGCAGGT
GGAAGTATGGTGTTCCTCCAGCCGGAAACGCTAATTATGCCTGGATACAGCATTTCCTTTATCATTTAGGTCCGAGCGGT
CAGGCCGGTTTTGTTCTGGCTAAGGGTTCTCTGACATCCAAATCATCGGGTGAGGGGGACATCAGAAAAGAGCTCGTAGA
GGCACGCCTGGTAGACTGCATAGTGAACCTTCCGCCAAAACTGTTCCTGAATACCCAGATCCCGGCAAGCCTCTGGTTCC
TGAGCAGGAATAAAGCCAACGGTAAGCACAGAAACAGGACTGATGAGATTCTGTTCATCGATGCACGGAACATGGGACAC
CTGATAAACCGCAGAACCCGTGAATTTTCACCTGAGGATATACAGCAGATTGCGGGCACCTACCATAAATGGCGCAATCC
GGAAGGGAATTACGAAGATGTGAAAGGATTCTGCAATTCCGCTCCAATTGAACGGGTACGTGAACTGGGCTATGTACTGA
CTCCGGGGCGCTATGTAGGATTGCCGGACGATGAAGATAATTTTGATTTCAATGAGCGCTTCTCCGCGCTGAAAGCCGAG
TTCGAGGAGCAGTTGAAAGAGGAAGAGAGACTGAACCTGCGGATCGCCGAGAATCTGAAAAAGGTGAAGCCGGCATGA

Upstream 100 bases:

>100_bases
AACTATCTCTGTGACTACGAAAACATCAAAACTGCATGAAACGGCTTTTGTACTGGTTCATTAAGCTGATTAACAATTTG
AATAATGGAAGGCATTAATT

Downstream 100 bases:

>100_bases
GTGGATGCGATCTGATAACAGTCTACCATTTCGGCGCTTCCCTGAAATACCTCGATAAGAAATGGTTCGCCTTCTCAAAA
ATGGATATAGGAGCAATTGA

Product: type I restriction-modification system specificity subunit

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MSDFEKQLWKAADKLRKNIDAAEYKHIVLGLIFLRYISDAFEELYEKLQQGEGEYAGADPEDRDEYKAENVFFVPAISRW
PYLQSEAKKPDIGKSVDNAMDAIEKENPLLRGVLPKVFARGNLDPTNLGGLIDLVSNVALGDAKSRSADVLGHVFEYFLG
EFALAEGKKGGQFYTPRSVVELLVEMLEPYNGRVFDPCCGSGGMFVQSEKFVADHQGKINDISIYGQESNQTTWRLAKMN
LAIRSIDSSQVKWNNEGSFLNDVHKDLKADYVIANPPFNDSDWSGDLLRKDGRWKYGVPPAGNANYAWIQHFLYHLGPSG
QAGFVLAKGSLTSKSSGEGDIRKELVEARLVDCIVNLPPKLFLNTQIPASLWFLSRNKANGKHRNRTDEILFIDARNMGH
LINRRTREFSPEDIQQIAGTYHKWRNPEGNYEDVKGFCNSAPIERVRELGYVLTPGRYVGLPDDEDNFDFNERFSALKAE
FEEQLKEEERLNLRIAENLKKVKPA

Sequences:

>Translated_505_residues
MSDFEKQLWKAADKLRKNIDAAEYKHIVLGLIFLRYISDAFEELYEKLQQGEGEYAGADPEDRDEYKAENVFFVPAISRW
PYLQSEAKKPDIGKSVDNAMDAIEKENPLLRGVLPKVFARGNLDPTNLGGLIDLVSNVALGDAKSRSADVLGHVFEYFLG
EFALAEGKKGGQFYTPRSVVELLVEMLEPYNGRVFDPCCGSGGMFVQSEKFVADHQGKINDISIYGQESNQTTWRLAKMN
LAIRSIDSSQVKWNNEGSFLNDVHKDLKADYVIANPPFNDSDWSGDLLRKDGRWKYGVPPAGNANYAWIQHFLYHLGPSG
QAGFVLAKGSLTSKSSGEGDIRKELVEARLVDCIVNLPPKLFLNTQIPASLWFLSRNKANGKHRNRTDEILFIDARNMGH
LINRRTREFSPEDIQQIAGTYHKWRNPEGNYEDVKGFCNSAPIERVRELGYVLTPGRYVGLPDDEDNFDFNERFSALKAE
FEEQLKEEERLNLRIAENLKKVKPA
>Mature_504_residues
SDFEKQLWKAADKLRKNIDAAEYKHIVLGLIFLRYISDAFEELYEKLQQGEGEYAGADPEDRDEYKAENVFFVPAISRWP
YLQSEAKKPDIGKSVDNAMDAIEKENPLLRGVLPKVFARGNLDPTNLGGLIDLVSNVALGDAKSRSADVLGHVFEYFLGE
FALAEGKKGGQFYTPRSVVELLVEMLEPYNGRVFDPCCGSGGMFVQSEKFVADHQGKINDISIYGQESNQTTWRLAKMNL
AIRSIDSSQVKWNNEGSFLNDVHKDLKADYVIANPPFNDSDWSGDLLRKDGRWKYGVPPAGNANYAWIQHFLYHLGPSGQ
AGFVLAKGSLTSKSSGEGDIRKELVEARLVDCIVNLPPKLFLNTQIPASLWFLSRNKANGKHRNRTDEILFIDARNMGHL
INRRTREFSPEDIQQIAGTYHKWRNPEGNYEDVKGFCNSAPIERVRELGYVLTPGRYVGLPDDEDNFDFNERFSALKAEF
EEQLKEEERLNLRIAENLKKVKPA

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=443, Percent_Identity=23.0248306997743, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 57158; Mature: 57027

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFEKQLWKAADKLRKNIDAAEYKHIVLGLIFLRYISDAFEELYEKLQQGEGEYAGADP
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EDRDEYKAENVFFVPAISRWPYLQSEAKKPDIGKSVDNAMDAIEKENPLLRGVLPKVFAR
CCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHC
GNLDPTNLGGLIDLVSNVALGDAKSRSADVLGHVFEYFLGEFALAEGKKGGQFYTPRSVV
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
ELLVEMLEPYNGRVFDPCCGSGGMFVQSEKFVADHQGKINDISIYGQESNQTTWRLAKMN
HHHHHHHCCCCCEEECCCCCCCCCEEECCHHHHCCCCCCEEEEEEECCCCCCEEEHHHHH
LAIRSIDSSQVKWNNEGSFLNDVHKDLKADYVIANPPFNDSDWSGDLLRKDGRWKYGVPP
HHHEECCCCCEEECCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHCCCCEECCCCC
AGNANYAWIQHFLYHLGPSGQAGFVLAKGSLTSKSSGEGDIRKELVEARLVDCIVNLPPK
CCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
LFLNTQIPASLWFLSRNKANGKHRNRTDEILFIDARNMGHLINRRTREFSPEDIQQIAGT
EEECCCCCHHEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHH
YHKWRNPEGNYEDVKGFCNSAPIERVRELGYVLTPGRYVGLPDDEDNFDFNERFSALKAE
HHHCCCCCCCHHHHHHHHCCCHHHHHHHCCEEECCCEEECCCCCCCCCCHHHHHHHHHHH
FEEQLKEEERLNLRIAENLKKVKPA
HHHHHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SDFEKQLWKAADKLRKNIDAAEYKHIVLGLIFLRYISDAFEELYEKLQQGEGEYAGADP
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EDRDEYKAENVFFVPAISRWPYLQSEAKKPDIGKSVDNAMDAIEKENPLLRGVLPKVFAR
CCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHC
GNLDPTNLGGLIDLVSNVALGDAKSRSADVLGHVFEYFLGEFALAEGKKGGQFYTPRSVV
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
ELLVEMLEPYNGRVFDPCCGSGGMFVQSEKFVADHQGKINDISIYGQESNQTTWRLAKMN
HHHHHHHCCCCCEEECCCCCCCCCEEECCHHHHCCCCCCEEEEEEECCCCCCEEEHHHHH
LAIRSIDSSQVKWNNEGSFLNDVHKDLKADYVIANPPFNDSDWSGDLLRKDGRWKYGVPP
HHHEECCCCCEEECCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHCCCCEECCCCC
AGNANYAWIQHFLYHLGPSGQAGFVLAKGSLTSKSSGEGDIRKELVEARLVDCIVNLPPK
CCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
LFLNTQIPASLWFLSRNKANGKHRNRTDEILFIDARNMGHLINRRTREFSPEDIQQIAGT
EEECCCCCHHEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHH
YHKWRNPEGNYEDVKGFCNSAPIERVRELGYVLTPGRYVGLPDDEDNFDFNERFSALKAE
HHHCCCCCCCHHHHHHHHCCCHHHHHHHCCEEECCCEEECCCCCCCCCCHHHHHHHHHHH
FEEQLKEEERLNLRIAENLKKVKPA
HHHHHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]