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The map label for this gene is ubiA

Identifier: 21228177

GI number: 21228177

Start: 2475006

End: 2475890

Strand: Direct

Name: ubiA

Synonym: MM_2075

Alternate gene names: NA

Gene position: 2475006-2475890 (Clockwise)

Preceding gene: 21228175

Following gene: 21228180

Centisome position: 60.42

GC content: 43.95

Gene sequence:

>885_bases
ATGCTGTTTCTTCTGATGTCTGCCGGAATACGAACATATCTTGAGCTCATGAGGTACAAAAACTGCCTGATGGCAGGTTT
TGCAGCAGCAATAGGAACTTTAATAGCGTTTAATATCCTCATTTCCGGAACTTCAACTCCAAATTTTGAGGATGCTTTCC
CCTTTCTTGATGCAGGCTTAGTATTTCTGGTGGTATTTTTAGTCTCGGGCGCAGGAAATGCGATTAACGATTACTTTGAC
ATCAAAATAGACTCTATCAACCGCCCTGAAAGACCCATCCCTTCCGGGAGGGTAAAAGCAAAAGAGGCTTTTTATTTTTC
TTACCTTCTGTTTGCTCTTGGCACTTTGATTGCTTTTTCCATAAATTCTATATGCGGGTCAATTGCTCTTTTTAATTCCC
TGCTATTGATCCTCTATGCAAAAACCCTTAAAGGCACTCCCCTTTTAGGAAACCTGAGTATAGGCTACCTTACAGGCTCC
GTTTTTTTATTCGGGGCTTCAATTTTTGGATTCGGAGGAATTAAGGCCCTTTCCGTACTTTTCCTGCTTGCTGCTCTTGC
CATTACAGCCCGTGAAATAGTAAAGGACATTGAGGACATGGAAGGCGACAGTCTGGAAGGAGCAGACACCCTGCCCCTGA
GGATCGGGGCAAAAAAAGCGGGTTATCTTGCGGTGCTTACAGGGCTCCTTGCAGTAATTTTAAGCCCTCTGCCTTATTTC
ATGTCTGTCCTTGGCCTGCGTTACATTTATCTTGTCTCTCTGGCAGACCTCGGATTTCTTGCAGCCATTATACAGCTCCT
CGTCCGAAATAACCCCACTAAATCCTCTAAACTGTTTAAAATAGCCATGTTTTTTGCCCTCATCGCGTTCATTGCAGGGG
TATGA

Upstream 100 bases:

>100_bases
TATTTTTCTCTCATGAGTATTTTTCTCTCATGAAGCTCTGGATGAATCAGCATGTAAGATTTAATCGTCGTCGTTTTTGG
CAAAATTTTAATACTTTATA

Downstream 100 bases:

>100_bases
ACCGAATAAATTTAATAATCTGTCAGGATTTGATCTCTTACAATAAATTTAATAATCTGTCAAGATTTGATCTCTTATTA
TTCTACCTCTTACTATTCCA

Product: prenyltransferase

Products: NA

Alternate protein names: DGGGP synthase; DGGGPS; (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Geranylgeranylglycerol-phosphate geranylgeranyltransferase [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MLFLLMSAGIRTYLELMRYKNCLMAGFAAAIGTLIAFNILISGTSTPNFEDAFPFLDAGLVFLVVFLVSGAGNAINDYFD
IKIDSINRPERPIPSGRVKAKEAFYFSYLLFALGTLIAFSINSICGSIALFNSLLLILYAKTLKGTPLLGNLSIGYLTGS
VFLFGASIFGFGGIKALSVLFLLAALAITAREIVKDIEDMEGDSLEGADTLPLRIGAKKAGYLAVLTGLLAVILSPLPYF
MSVLGLRYIYLVSLADLGFLAAIIQLLVRNNPTKSSKLFKIAMFFALIAFIAGV

Sequences:

>Translated_294_residues
MLFLLMSAGIRTYLELMRYKNCLMAGFAAAIGTLIAFNILISGTSTPNFEDAFPFLDAGLVFLVVFLVSGAGNAINDYFD
IKIDSINRPERPIPSGRVKAKEAFYFSYLLFALGTLIAFSINSICGSIALFNSLLLILYAKTLKGTPLLGNLSIGYLTGS
VFLFGASIFGFGGIKALSVLFLLAALAITAREIVKDIEDMEGDSLEGADTLPLRIGAKKAGYLAVLTGLLAVILSPLPYF
MSVLGLRYIYLVSLADLGFLAAIIQLLVRNNPTKSSKLFKIAMFFALIAFIAGV
>Mature_294_residues
MLFLLMSAGIRTYLELMRYKNCLMAGFAAAIGTLIAFNILISGTSTPNFEDAFPFLDAGLVFLVVFLVSGAGNAINDYFD
IKIDSINRPERPIPSGRVKAKEAFYFSYLLFALGTLIAFSINSICGSIALFNSLLLILYAKTLKGTPLLGNLSIGYLTGS
VFLFGASIFGFGGIKALSVLFLLAALAITAREIVKDIEDMEGDSLEGADTLPLRIGAKKAGYLAVLTGLLAVILSPLPYF
MSVLGLRYIYLVSLADLGFLAAIIQLLVRNNPTKSSKLFKIAMFFALIAFIAGV

Specific function: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesi

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. DGGGP synthase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: =2.5.1.42 [H]

Molecular weight: Translated: 31610; Mature: 31610

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFLLMSAGIRTYLELMRYKNCLMAGFAAAIGTLIAFNILISGTSTPNFEDAFPFLDAGL
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHH
VFLVVFLVSGAGNAINDYFDIKIDSINRPERPIPSGRVKAKEAFYFSYLLFALGTLIAFS
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
INSICGSIALFNSLLLILYAKTLKGTPLLGNLSIGYLTGSVFLFGASIFGFGGIKALSVL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
FLLAALAITAREIVKDIEDMEGDSLEGADTLPLRIGAKKAGYLAVLTGLLAVILSPLPYF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCHHHH
MSVLGLRYIYLVSLADLGFLAAIIQLLVRNNPTKSSKLFKIAMFFALIAFIAGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLFLLMSAGIRTYLELMRYKNCLMAGFAAAIGTLIAFNILISGTSTPNFEDAFPFLDAGL
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHH
VFLVVFLVSGAGNAINDYFDIKIDSINRPERPIPSGRVKAKEAFYFSYLLFALGTLIAFS
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
INSICGSIALFNSLLLILYAKTLKGTPLLGNLSIGYLTGSVFLFGASIFGFGGIKALSVL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
FLLAALAITAREIVKDIEDMEGDSLEGADTLPLRIGAKKAGYLAVLTGLLAVILSPLPYF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCHHHH
MSVLGLRYIYLVSLADLGFLAAIIQLLVRNNPTKSSKLFKIAMFFALIAFIAGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]