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The map label for this gene is nadX

Identifier: 21228174

GI number: 21228174

Start: 2470547

End: 2471200

Strand: Direct

Name: nadX

Synonym: MM_2072

Alternate gene names: 21228174

Gene position: 2470547-2471200 (Clockwise)

Preceding gene: 21228168

Following gene: 21228175

Centisome position: 60.31

GC content: 45.26

Gene sequence:

>654_bases
ATGAAGATTGAAGAACTTATTAGCAGTGTAGACCTTGTTGTTGAAAGCGCTTCTCAGAATGCTGTCAGGTTTATCGTACC
TCAGGCCCTTAAAGCCGGATGCAGTGTAATGGTGCTGAGTGTGGGTGCTCTTGCAGATAAAGAATTGAGAGAAACTCTTT
TCGGGCTTGCAAAAAAGCATAACTGCAAGCTTTACTTCCCCTCGGGTGCCGTTGTCGGAATCGATGGTATTAATTCAGCG
CATGCCGCCGGGATTTCTTCTGTTACCCTGACAACCAGGAAACCTCCTTCCGGACTTATGGGGGCCCCTTATGTTGTGGA
ACATGGCATAGAACTTGAGAAGCTCGAAAAAGAGACCATTCTTTTTGAAGGGACTGCCTCAGAAGCCGTAAAAGCCTTCC
CCGCAAACGTTAACGTTGCAGCCACTATAAGCCTTGCAGGTATAGGTTTTGAAAGGACGATGGTGAGAGTTATAGCTGAT
CCGTCCCTTTCGAGGAACATTCATGAAATTAATGTAGAGGGAGAGTTTGGGAAATTCTGTACAAAGGTAGAAAACCTTCC
TTCTCCGGAAAATCCTAAAACAAGTTATCTTGCAGCCCTTTCTGCGATCTCAACCCTGAAAAAGATACTTAATCCTGTCC
AGATAGGAACCTGA

Upstream 100 bases:

>100_bases
CAGCGGAGAGATTGATGCTGAGCTATATGCCTTATGTGACTCTTCTGAAAGCAAAGCCTTTGGTCTTGCAAAGTCCCTGA
ATACCTGCAAGCCTGCATAT

Downstream 100 bases:

>100_bases
AGCCCGTTAATATTTCATTCCTGGTGAACATTTGGGTTCTGGTCTTATCTCCAGTACAGATCCTATCTACAATTCAGCCT
TGAATTGGAAGGGATAGAGT

Product: putative dinucleotide-utilizing enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKIEELISSVDLVVESASQNAVRFIVPQALKAGCSVMVLSVGALADKELRETLFGLAKKHNCKLYFPSGAVVGIDGINSA
HAAGISSVTLTTRKPPSGLMGAPYVVEHGIELEKLEKETILFEGTASEAVKAFPANVNVAATISLAGIGFERTMVRVIAD
PSLSRNIHEINVEGEFGKFCTKVENLPSPENPKTSYLAALSAISTLKKILNPVQIGT

Sequences:

>Translated_217_residues
MKIEELISSVDLVVESASQNAVRFIVPQALKAGCSVMVLSVGALADKELRETLFGLAKKHNCKLYFPSGAVVGIDGINSA
HAAGISSVTLTTRKPPSGLMGAPYVVEHGIELEKLEKETILFEGTASEAVKAFPANVNVAATISLAGIGFERTMVRVIAD
PSLSRNIHEINVEGEFGKFCTKVENLPSPENPKTSYLAALSAISTLKKILNPVQIGT
>Mature_217_residues
MKIEELISSVDLVVESASQNAVRFIVPQALKAGCSVMVLSVGALADKELRETLFGLAKKHNCKLYFPSGAVVGIDGINSA
HAAGISSVTLTTRKPPSGLMGAPYVVEHGIELEKLEKETILFEGTASEAVKAFPANVNVAATISLAGIGFERTMVRVIAD
PSLSRNIHEINVEGEFGKFCTKVENLPSPENPKTSYLAALSAISTLKKILNPVQIGT

Specific function: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate

COG id: COG1712

COG function: function code R; Predicted dinucleotide-utilizing enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L-aspartate dehydrogenase family

Homologues:

Organism=Caenorhabditis elegans, GI71984591, Length=210, Percent_Identity=29.0476190476191, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASPD_METMA (Q8PV99)

Other databases:

- EMBL:   AE008384
- RefSeq:   NP_634096.1
- ProteinModelPortal:   Q8PV99
- SMR:   Q8PV99
- GeneID:   1480414
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_2072
- NMPDR:   fig|192952.1.peg.2072
- HOGENOM:   HBG649642
- OMA:   ECAGHSA
- BioCyc:   MMAZ192952:MM2072-MONOMER
- BRENDA:   1.4.1.21
- HAMAP:   MF_01265
- InterPro:   IPR005106
- InterPro:   IPR002811
- InterPro:   IPR011182
- InterPro:   IPR020626
- InterPro:   IPR022487
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF005227
- TIGRFAMs:   TIGR03855

Pfam domain/function: PF01958 DUF108; PF03447 NAD_binding_3

EC number: =1.4.1.21

Molecular weight: Translated: 22990; Mature: 22990

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: ACT_SITE 222-222 BINDING 124-124 BINDING 192-192

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEELISSVDLVVESASQNAVRFIVPQALKAGCSVMVLSVGALADKELRETLFGLAKKH
CCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCEEEEEEHHHHCHHHHHHHHHHHHHCC
NCKLYFPSGAVVGIDGINSAHAAGISSVTLTTRKPPSGLMGAPYVVEHGIELEKLEKETI
CCEEECCCCCEEEECCCCCHHHCCCCEEEEEECCCCCCCCCCCHHHHCCCCHHHHCCEEE
LFEGTASEAVKAFPANVNVAATISLAGIGFERTMVRVIADPSLSRNIHEINVEGEFGKFC
EEECCHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHEEECCCCCCCEEEEEECCCHHHHH
TKVENLPSPENPKTSYLAALSAISTLKKILNPVQIGT
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIEELISSVDLVVESASQNAVRFIVPQALKAGCSVMVLSVGALADKELRETLFGLAKKH
CCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCEEEEEEHHHHCHHHHHHHHHHHHHCC
NCKLYFPSGAVVGIDGINSAHAAGISSVTLTTRKPPSGLMGAPYVVEHGIELEKLEKETI
CCEEECCCCCEEEECCCCCHHHCCCCEEEEEECCCCCCCCCCCHHHHCCCCHHHHCCEEE
LFEGTASEAVKAFPANVNVAATISLAGIGFERTMVRVIADPSLSRNIHEINVEGEFGKFC
EEECCHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHEEECCCCCCCEEEEEECCCHHHHH
TKVENLPSPENPKTSYLAALSAISTLKKILNPVQIGT
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824