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The map label for this gene is eIF1A1 [H]

Identifier: 21228116

GI number: 21228116

Start: 2399517

End: 2399792

Strand: Reverse

Name: eIF1A1 [H]

Synonym: MM_2014

Alternate gene names: 21228116

Gene position: 2399792-2399517 (Counterclockwise)

Preceding gene: 21228117

Following gene: 21228115

Centisome position: 58.58

GC content: 48.91

Gene sequence:

>276_bases
GTGACAAGAGTGCGCACTCCGCGCAGGGAAAACAACGAAATCCTGGCAACTGTAGAAAGTCTCCTTGGTGCAAACAGGCT
CAGACTCCGCTGTATGGATGGAGTCGTCCGTATGGGAAGAATTCCGGGGTCAATGAAGAAAAAGGCCTGGATTAGAGAAG
GAGACGTCGTCATTGCCGTGCCCTGGGAATTCCAGAATGAAAAAGCAGATGTGATCTGGAAATACACAAGGCCGCAGGTA
GACTGGCTTGAAAGAAAAGGATACCTTAAAGGATAA

Upstream 100 bases:

>100_bases
AAAAGATGAAATAATAATTACAAATTACATGTAATGAGGTATCACACTGGCAGACTTAAAGAAACCTACATCAAGAGCCT
CTCCCAGCACAGAAGAGACC

Downstream 100 bases:

>100_bases
ACATGAGCAGGGATCTGGAAGAGAAAGTAAAGCGCATTGACAGTGCTACAGACAAAGCCCGGGCAAGAGAAAAAGACTCT
GATCGGCTGAAGGTGGAAGA

Product: translation initiation factor IF-1A

Products: NA

Alternate protein names: aIF-1A 1 [H]

Number of amino acids: Translated: 91; Mature: 90

Protein sequence:

>91_residues
MTRVRTPRRENNEILATVESLLGANRLRLRCMDGVVRMGRIPGSMKKKAWIREGDVVIAVPWEFQNEKADVIWKYTRPQV
DWLERKGYLKG

Sequences:

>Translated_91_residues
MTRVRTPRRENNEILATVESLLGANRLRLRCMDGVVRMGRIPGSMKKKAWIREGDVVIAVPWEFQNEKADVIWKYTRPQV
DWLERKGYLKG
>Mature_90_residues
TRVRTPRRENNEILATVESLLGANRLRLRCMDGVVRMGRIPGSMKKKAWIREGDVVIAVPWEFQNEKADVIWKYTRPQVD
WLERKGYLKG

Specific function: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits [H]

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323916, Length=81, Percent_Identity=32.0987654320988, Blast_Score=60, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45553405, Length=68, Percent_Identity=42.6470588235294, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24647907, Length=68, Percent_Identity=42.6470588235294, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR006196
- InterPro:   IPR001253
- InterPro:   IPR018104
- ProDom:   PD005579 [H]

Pfam domain/function: PF01176 eIF-1a [H]

EC number: NA

Molecular weight: Translated: 10685; Mature: 10553

Theoretical pI: Translated: 10.92; Mature: 10.92

Prosite motif: PS50832 S1_IF1_TYPE ; PS01262 IF1A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVRTPRRENNEILATVESLLGANRLRLRCMDGVVRMGRIPGSMKKKAWIREGDVVIAV
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCCCCEECCCCEEEEE
PWEFQNEKADVIWKYTRPQVDWLERKGYLKG
CCCCCCCCCEEEEEECCCCCHHHHCCCCCCC
>Mature Secondary Structure 
TRVRTPRRENNEILATVESLLGANRLRLRCMDGVVRMGRIPGSMKKKAWIREGDVVIAV
CCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCCCCEECCCCEEEEE
PWEFQNEKADVIWKYTRPQVDWLERKGYLKG
CCCCCCCCCEEEEEECCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]