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The map label for this gene is chlD

Identifier: 21228105

GI number: 21228105

Start: 2386798

End: 2388876

Strand: Direct

Name: chlD

Synonym: MM_2003

Alternate gene names: NA

Gene position: 2386798-2388876 (Clockwise)

Preceding gene: 21228104

Following gene: 21228106

Centisome position: 58.27

GC content: 46.85

Gene sequence:

>2079_bases
ATGAAGAACCATAATATTGCTGTCTATCCCTTTACCGCCATAGTCGGGCAGGAGAAAATGAAAAAAGCCCTTGTCCTGAA
TCTCATTAACCCTAAACTTGGCGGAGTCCTTGTCAGAGGGGAAAAAGGCACTGCCAAATCAACGGCAGTACGGGCCCTTG
CAAACCTCCTGCCTGAAATCGAAGTCGTTGAGGGCTGTAAATTCAAATGCAATCCTCAATATCAAAAAGAACTGTGTGAG
GAATGCCTTGGAAAACTAAATGCAGGAAACCTGAGAGTTTCCCGGATAAAAATGAAGGTAGTGGACCTCCCCGTAAGCGC
CACCGAGGACAGAGTTGTCGGAACCCTTGATATTGAACATGCTATTAAAAAAGGAGAAAAACGTTTTGAGCCGGGTGTGC
TTGCAATGGCTCACAGGGGCATCCTGTACGTGGACGAGATCAACCTCCTGGATGACCACATTGTAGATGTACTTCTTGAC
TCTGCGGCAATGGGGGTAAATACTGTTGAGCGCGAAGGGATTTCTTACTCCCATCCTGCAAACTTTGTGCTCGTGGGCAC
CATGAACCCTGAGGAAGGGGAACTGCGTCCTCAGCTTCTTGACCGTTTCGGCTTATGTGTGGATGTAAAAGGCATCAGTG
ATGTTTCCAGAAGGGTTGAGCTTATAAAATACAGGCTCAGTTACGAGGCAGACCCTGAGGGCTTTGCAGCAAACTGGCAG
GCTGCCGAAACCGAGCTTTGCGGACAGATCCTCACCGCGAAGCAGCTTCTTTCCGAAGTTCGGATTTCGGACGATATGCT
TGAGCTGATCAGCCAGATCTGCGTTGATATGGGTGTTGACGGGCACAGGGCAGACATAACAATGATGAAAACCTCAATCA
CTCTTTCAGCTTTTAACGGGAGGGCTGACGTTCTTGAAGAAGACGTAAAAGAAGCTGCAGAACTTGTGCTTTCTCACCGC
ATGCGCAGAAAACCTTTTGATTCTCATTCCGACAAACAGGATAAGCTGGATGAAAGCATTGAAAAACACAGGGAAAAACA
GAAAGAGAAGAATAAAGAGAAAGAGCAAAATAGAGATCAAAATAATCAGGAACAGCAGAAGCAGGACCGTAAAGAAAACC
CTGAAAAAACTCACGAACACCCGGAAGGGCAGCAGCCGGAAAACGCACAGAGCAATGCCGAAGGGCAGCCTGATGCCTCT
TCAGAAACTATTTTTGCTACAGGGGAAAGCTATCAGATAAAACAGCTTGCTCCTGAATTTATCAGGGCTGACCGGAAAGG
GTCGGGCAGGCGAAGTAAAACCTTTACCAGTTCCAGACAGGGCAGGTATATAAAGAGTGCAATTCCTCATGAAAAAACCA
CAGACCTTGCCTTCGATGCTACTCTCAGGGCAGCTGCTCCTTATCAGCTCACAAGGGAAAAGAACGGAAATTCCATAATA
ATTCATGATCCTGACTTAAGAAAAAAAATTCGTGAGAAAAAGATTGGCAACCTTGTCCTTTTTGTGGTGGATGCCAGCGG
TTCCATGGGAGCCAGGCAGAGAATGGTTGCGTCCAAAGGTGCGGTCCTTTCCATGCTGATGGATGCTTACCAGAAACGGG
ACAGAGTAGGGCTTATCGCATTTAAAGGAGATAGCGCAGAACTGTTGCTGCCTCCGACTTCCAGTATAGAACTGGCTCAA
AAATATCTTCAGGAGATGCCCACGGGAGGGAAGACTCCGATTTCCAGGGGGCTTGTAAAGGGGTATGAGATTATAAAAAG
CGAACTCAGGCGTGACCCTGACACCTGCCCTTTTATGGTCCTTATCTCTGACGGCAGGGCAAATGTAAGCATGAACGGCG
AACCTCCTCTCCATGAAATAATCACAATAGCATCCAGGTTAAAGGAGGAAGGCATCCAGTCTGCTGTAATTGATACGGAA
AGCAGTATGATTAAATTTGGGTTTGCACAGCAGATCTCCACAGCTCTTGGAGCTACCTATCTCACTCTTGAAAATTTAAA
AGCGGATTCTATAGTTAATGCTGTTAGAGCTTCAGCCCCGTTTGAAATCATGATGCATCCCGGCGTTTCTTCAGTTTGA

Upstream 100 bases:

>100_bases
ATGTAAGGTCCATCCTTCCGTCCGTTTCAAGCTGGTCCATACCGGCTATGAGTATTGAAGAATACCTGATAGGAGTCTGA
AAATAAACCGGGGCAAAAAT

Downstream 100 bases:

>100_bases
GTTTATTAAGATTCTTGTATTTTTTCGGGTATGGAGAGCTTTTTCAGGGTGAGACTTCATTTCTCAAAAATACAACAAAA
GCTATATGTCTATCTTAAGC

Product: magnesium-chelatase subunit

Products: ADP; phosphate; Mg-protoporphyrin IX; H+

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MKNHNIAVYPFTAIVGQEKMKKALVLNLINPKLGGVLVRGEKGTAKSTAVRALANLLPEIEVVEGCKFKCNPQYQKELCE
ECLGKLNAGNLRVSRIKMKVVDLPVSATEDRVVGTLDIEHAIKKGEKRFEPGVLAMAHRGILYVDEINLLDDHIVDVLLD
SAAMGVNTVEREGISYSHPANFVLVGTMNPEEGELRPQLLDRFGLCVDVKGISDVSRRVELIKYRLSYEADPEGFAANWQ
AAETELCGQILTAKQLLSEVRISDDMLELISQICVDMGVDGHRADITMMKTSITLSAFNGRADVLEEDVKEAAELVLSHR
MRRKPFDSHSDKQDKLDESIEKHREKQKEKNKEKEQNRDQNNQEQQKQDRKENPEKTHEHPEGQQPENAQSNAEGQPDAS
SETIFATGESYQIKQLAPEFIRADRKGSGRRSKTFTSSRQGRYIKSAIPHEKTTDLAFDATLRAAAPYQLTREKNGNSII
IHDPDLRKKIREKKIGNLVLFVVDASGSMGARQRMVASKGAVLSMLMDAYQKRDRVGLIAFKGDSAELLLPPTSSIELAQ
KYLQEMPTGGKTPISRGLVKGYEIIKSELRRDPDTCPFMVLISDGRANVSMNGEPPLHEIITIASRLKEEGIQSAVIDTE
SSMIKFGFAQQISTALGATYLTLENLKADSIVNAVRASAPFEIMMHPGVSSV

Sequences:

>Translated_692_residues
MKNHNIAVYPFTAIVGQEKMKKALVLNLINPKLGGVLVRGEKGTAKSTAVRALANLLPEIEVVEGCKFKCNPQYQKELCE
ECLGKLNAGNLRVSRIKMKVVDLPVSATEDRVVGTLDIEHAIKKGEKRFEPGVLAMAHRGILYVDEINLLDDHIVDVLLD
SAAMGVNTVEREGISYSHPANFVLVGTMNPEEGELRPQLLDRFGLCVDVKGISDVSRRVELIKYRLSYEADPEGFAANWQ
AAETELCGQILTAKQLLSEVRISDDMLELISQICVDMGVDGHRADITMMKTSITLSAFNGRADVLEEDVKEAAELVLSHR
MRRKPFDSHSDKQDKLDESIEKHREKQKEKNKEKEQNRDQNNQEQQKQDRKENPEKTHEHPEGQQPENAQSNAEGQPDAS
SETIFATGESYQIKQLAPEFIRADRKGSGRRSKTFTSSRQGRYIKSAIPHEKTTDLAFDATLRAAAPYQLTREKNGNSII
IHDPDLRKKIREKKIGNLVLFVVDASGSMGARQRMVASKGAVLSMLMDAYQKRDRVGLIAFKGDSAELLLPPTSSIELAQ
KYLQEMPTGGKTPISRGLVKGYEIIKSELRRDPDTCPFMVLISDGRANVSMNGEPPLHEIITIASRLKEEGIQSAVIDTE
SSMIKFGFAQQISTALGATYLTLENLKADSIVNAVRASAPFEIMMHPGVSSV
>Mature_692_residues
MKNHNIAVYPFTAIVGQEKMKKALVLNLINPKLGGVLVRGEKGTAKSTAVRALANLLPEIEVVEGCKFKCNPQYQKELCE
ECLGKLNAGNLRVSRIKMKVVDLPVSATEDRVVGTLDIEHAIKKGEKRFEPGVLAMAHRGILYVDEINLLDDHIVDVLLD
SAAMGVNTVEREGISYSHPANFVLVGTMNPEEGELRPQLLDRFGLCVDVKGISDVSRRVELIKYRLSYEADPEGFAANWQ
AAETELCGQILTAKQLLSEVRISDDMLELISQICVDMGVDGHRADITMMKTSITLSAFNGRADVLEEDVKEAAELVLSHR
MRRKPFDSHSDKQDKLDESIEKHREKQKEKNKEKEQNRDQNNQEQQKQDRKENPEKTHEHPEGQQPENAQSNAEGQPDAS
SETIFATGESYQIKQLAPEFIRADRKGSGRRSKTFTSSRQGRYIKSAIPHEKTTDLAFDATLRAAAPYQLTREKNGNSII
IHDPDLRKKIREKKIGNLVLFVVDASGSMGARQRMVASKGAVLSMLMDAYQKRDRVGLIAFKGDSAELLLPPTSSIELAQ
KYLQEMPTGGKTPISRGLVKGYEIIKSELRRDPDTCPFMVLISDGRANVSMNGEPPLHEIITIASRLKEEGIQSAVIDTE
SSMIKFGFAQQISTALGATYLTLENLKADSIVNAVRASAPFEIMMHPGVSSV

Specific function: Unknown

COG id: COG1239

COG function: function code H; Mg-chelatase subunit ChlI

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011704
- InterPro:   IPR012804
- InterPro:   IPR002035 [H]

Pfam domain/function: PF07728 AAA_5; PF00092 VWA [H]

EC number: 6.6.1.1

Molecular weight: Translated: 76786; Mature: 76786

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNHNIAVYPFTAIVGQEKMKKALVLNLINPKLGGVLVRGEKGTAKSTAVRALANLLPEI
CCCCCEEEEEHHHHHCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCC
EVVEGCKFKCNPQYQKELCEECLGKLNAGNLRVSRIKMKVVDLPVSATEDRVVGTLDIEH
EECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCEEEEEEHHH
AIKKGEKRFEPGVLAMAHRGILYVDEINLLDDHIVDVLLDSAAMGVNTVEREGISYSHPA
HHHCCHHHCCCCCEEHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCC
NFVLVGTMNPEEGELRPQLLDRFGLCVDVKGISDVSRRVELIKYRLSYEADPEGFAANWQ
CEEEEECCCCCCCCCCHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AAETELCGQILTAKQLLSEVRISDDMLELISQICVDMGVDGHRADITMMKTSITLSAFNG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEECCC
RADVLEEDVKEAAELVLSHRMRRKPFDSHSDKQDKLDESIEKHREKQKEKNKEKEQNRDQ
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NNQEQQKQDRKENPEKTHEHPEGQQPENAQSNAEGQPDASSETIFATGESYQIKQLAPEF
CCHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHCHHH
IRADRKGSGRRSKTFTSSRQGRYIKSAIPHEKTTDLAFDATLRAAAPYQLTREKNGNSII
HHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEHHHHHCCCCCCEEECCCCCEEE
IHDPDLRKKIREKKIGNLVLFVVDASGSMGARQRMVASKGAVLSMLMDAYQKRDRVGLIA
EECCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCEEEEE
FKGDSAELLLPPTSSIELAQKYLQEMPTGGKTPISRGLVKGYEIIKSELRRDPDTCPFMV
EECCCCEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEE
LISDGRANVSMNGEPPLHEIITIASRLKEEGIQSAVIDTESSMIKFGFAQQISTALGATY
EEECCCCEEECCCCCCHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LTLENLKADSIVNAVRASAPFEIMMHPGVSSV
EEHHCCCHHHHHHHHHCCCCEEEEECCCCCCC
>Mature Secondary Structure
MKNHNIAVYPFTAIVGQEKMKKALVLNLINPKLGGVLVRGEKGTAKSTAVRALANLLPEI
CCCCCEEEEEHHHHHCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCC
EVVEGCKFKCNPQYQKELCEECLGKLNAGNLRVSRIKMKVVDLPVSATEDRVVGTLDIEH
EECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCEEEEEEHHH
AIKKGEKRFEPGVLAMAHRGILYVDEINLLDDHIVDVLLDSAAMGVNTVEREGISYSHPA
HHHCCHHHCCCCCEEHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCC
NFVLVGTMNPEEGELRPQLLDRFGLCVDVKGISDVSRRVELIKYRLSYEADPEGFAANWQ
CEEEEECCCCCCCCCCHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AAETELCGQILTAKQLLSEVRISDDMLELISQICVDMGVDGHRADITMMKTSITLSAFNG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEECCC
RADVLEEDVKEAAELVLSHRMRRKPFDSHSDKQDKLDESIEKHREKQKEKNKEKEQNRDQ
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NNQEQQKQDRKENPEKTHEHPEGQQPENAQSNAEGQPDASSETIFATGESYQIKQLAPEF
CCHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHCHHH
IRADRKGSGRRSKTFTSSRQGRYIKSAIPHEKTTDLAFDATLRAAAPYQLTREKNGNSII
HHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEHHHHHCCCCCCEEECCCCCEEE
IHDPDLRKKIREKKIGNLVLFVVDASGSMGARQRMVASKGAVLSMLMDAYQKRDRVGLIA
EECCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCEEEEE
FKGDSAELLLPPTSSIELAQKYLQEMPTGGKTPISRGLVKGYEIIKSELRRDPDTCPFMV
EECCCCEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEE
LISDGRANVSMNGEPPLHEIITIASRLKEEGIQSAVIDTESSMIKFGFAQQISTALGATY
EEECCCCEEECCCCCCHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LTLENLKADSIVNAVRASAPFEIMMHPGVSSV
EEHHCCCHHHHHHHHHCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; protoporphyrin IX; Mg2+; H2O

Specific reaction: ATP + protoporphyrin IX + Mg2+ + H2O = ADP + phosphate + Mg-protoporphyrin IX + 2 H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]