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The map label for this gene is yccK [H]

Identifier: 21228050

GI number: 21228050

Start: 2316651

End: 2317778

Strand: Direct

Name: yccK [H]

Synonym: MM_1948

Alternate gene names: 21228050

Gene position: 2316651-2317778 (Clockwise)

Preceding gene: 21228046

Following gene: 21228052

Centisome position: 56.55

GC content: 44.59

Gene sequence:

>1128_bases
ATGTTATACAGAAGACTTGGCAGGACGGACGAAAAAGTTTCCATACTGGGTTTTGGCACCATGCGTCTCCCTGTTATAGG
GGGAGATGATACCCGGGTTGATGAGGAAAAATCCATAGAGATGATCCGTTATGCCATCGATTCCGGTGTTAATTACATTG
ATACTGCCTATCCTTACCATGGTGGCATGAGCGAATCCGTTCTCGGGAAGGCTCTTGAAGACGGCTACCGTGATAAAGTC
TATATCGCAACCAAACTCCCGAGCTGGCTGGTTGCAAGCAGAAAAGACATGGACAGGTATTTGAACGAACAGCTTGAAAG
GCTTAAAACTGATTCCATTGATTTCTATCTGGCGCACGCTTTAAACAGTGACTTCTGGGATCTGGTTAAAAAGCATGGAA
TTTTTGATTTCCTTGACTCTGCCCTTGAGGATGGCAGAATAAAATATACGGGATTCTCCTTCCATGACAGCCCTGAATTG
TTTAAGGAAATAGTCGATTCCTACCCGTGGACTCTATGTCAGATACAGTACAACTTTATGGATGAAAATTTCCAGGCAGG
AAAAGACGGTTTGATGTATGCCGCGTCAAAGGGCCTTGGTATAGTTATTATGGAGCCCATGCGAGGGGGTTACCTTGTCT
CAGGGATGCCACCTGAAATTCAGGAAATCTGGGATTCTGCTGATATACAGAGAAGCCCTGTTGAATGGAGCCTTCGATAT
CTGTGGGACTATCCGGAAATAGCTGTGGTACTTAGCGGGATGTCTGAGATAAAACATGTTGAAGATAACGTAAAATTCGC
GTCTGGAGGTCTTCCGGACTCCCTGACTGAGAGGGAAAGAGAGCTCATTTCGCGTGTAAAAAAAATCTACATGTCAAAGA
CCAGGGTTAACTGTACCGGATGCCGGTATTGTATGCCCTGCCCTTCAGGAGTGAATATCCCTGAGAATTTCAAGTACCTC
AATAATGCTGAAATGTTTGATAACGCAGAAGGAGAAAAAGCTCTGTACAGCGGCCTTGAAGGACAGGCTTCAAACTGTAC
GGAATGCGGACAGTGTGAAGAAAAGTGCCCTCAAAAAATTCCTGTCAGTCAGATGCTAAAAGAGGTTGTTAAATTATTTG
GGAAATGA

Upstream 100 bases:

>100_bases
TGTAGCTTACACAAAGCGTTATCTTCTATCATGACAAAGGGGGGTAAGGGATTCATTTCGATATGGGTTTCAAGTATTTT
TCTTGAGGGGGCAAAAATAT

Downstream 100 bases:

>100_bases
TCCCCTCAAAATCAAAAATGGGTCATGCAGTCGCCTTAAAAACCGGAACCACAGTATGTAAGTATTATATTGGACTGCAG
GTTTTTCTCCGGGCTGTTAT

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MLYRRLGRTDEKVSILGFGTMRLPVIGGDDTRVDEEKSIEMIRYAIDSGVNYIDTAYPYHGGMSESVLGKALEDGYRDKV
YIATKLPSWLVASRKDMDRYLNEQLERLKTDSIDFYLAHALNSDFWDLVKKHGIFDFLDSALEDGRIKYTGFSFHDSPEL
FKEIVDSYPWTLCQIQYNFMDENFQAGKDGLMYAASKGLGIVIMEPMRGGYLVSGMPPEIQEIWDSADIQRSPVEWSLRY
LWDYPEIAVVLSGMSEIKHVEDNVKFASGGLPDSLTERERELISRVKKIYMSKTRVNCTGCRYCMPCPSGVNIPENFKYL
NNAEMFDNAEGEKALYSGLEGQASNCTECGQCEEKCPQKIPVSQMLKEVVKLFGK

Sequences:

>Translated_375_residues
MLYRRLGRTDEKVSILGFGTMRLPVIGGDDTRVDEEKSIEMIRYAIDSGVNYIDTAYPYHGGMSESVLGKALEDGYRDKV
YIATKLPSWLVASRKDMDRYLNEQLERLKTDSIDFYLAHALNSDFWDLVKKHGIFDFLDSALEDGRIKYTGFSFHDSPEL
FKEIVDSYPWTLCQIQYNFMDENFQAGKDGLMYAASKGLGIVIMEPMRGGYLVSGMPPEIQEIWDSADIQRSPVEWSLRY
LWDYPEIAVVLSGMSEIKHVEDNVKFASGGLPDSLTERERELISRVKKIYMSKTRVNCTGCRYCMPCPSGVNIPENFKYL
NNAEMFDNAEGEKALYSGLEGQASNCTECGQCEEKCPQKIPVSQMLKEVVKLFGK
>Mature_375_residues
MLYRRLGRTDEKVSILGFGTMRLPVIGGDDTRVDEEKSIEMIRYAIDSGVNYIDTAYPYHGGMSESVLGKALEDGYRDKV
YIATKLPSWLVASRKDMDRYLNEQLERLKTDSIDFYLAHALNSDFWDLVKKHGIFDFLDSALEDGRIKYTGFSFHDSPEL
FKEIVDSYPWTLCQIQYNFMDENFQAGKDGLMYAASKGLGIVIMEPMRGGYLVSGMPPEIQEIWDSADIQRSPVEWSLRY
LWDYPEIAVVLSGMSEIKHVEDNVKFASGGLPDSLTERERELISRVKKIYMSKTRVNCTGCRYCMPCPSGVNIPENFKYL
NNAEMFDNAEGEKALYSGLEGQASNCTECGQCEEKCPQKIPVSQMLKEVVKLFGK

Specific function: Unknown

COG id: COG1453

COG function: function code R; Predicted oxidoreductases of the aldo/keto reductase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Escherichia coli, GI87081735, Length=229, Percent_Identity=28.3842794759825, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI212645785, Length=306, Percent_Identity=25.8169934640523, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646159, Length=221, Percent_Identity=29.8642533936652, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24646155, Length=326, Percent_Identity=24.8466257668712, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 42689; Mature: 42689

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYRRLGRTDEKVSILGFGTMRLPVIGGDDTRVDEEKSIEMIRYAIDSGVNYIDTAYPYH
CCCCCCCCCCCCEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
GGMSESVLGKALEDGYRDKVYIATKLPSWLVASRKDMDRYLNEQLERLKTDSIDFYLAHA
CCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LNSDFWDLVKKHGIFDFLDSALEDGRIKYTGFSFHDSPELFKEIVDSYPWTLCQIQYNFM
HCCHHHHHHHHCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEECCC
DENFQAGKDGLMYAASKGLGIVIMEPMRGGYLVSGMPPEIQEIWDSADIQRSPVEWSLRY
CCCCCCCCCCEEEEECCCCEEEEECCCCCCEEECCCCHHHHHHHCCCCCCCCCHHEEHHH
LWDYPEIAVVLSGMSEIKHVEDNVKFASGGLPDSLTERERELISRVKKIYMSKTRVNCTG
HCCCHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
CRYCMPCPSGVNIPENFKYLNNAEMFDNAEGEKALYSGLEGQASNCTECGQCEEKCPQKI
CCEECCCCCCCCCCCCCHHCCCCHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCC
PVSQMLKEVVKLFGK
CHHHHHHHHHHHHCC
>Mature Secondary Structure
MLYRRLGRTDEKVSILGFGTMRLPVIGGDDTRVDEEKSIEMIRYAIDSGVNYIDTAYPYH
CCCCCCCCCCCCEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
GGMSESVLGKALEDGYRDKVYIATKLPSWLVASRKDMDRYLNEQLERLKTDSIDFYLAHA
CCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LNSDFWDLVKKHGIFDFLDSALEDGRIKYTGFSFHDSPELFKEIVDSYPWTLCQIQYNFM
HCCHHHHHHHHCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEECCC
DENFQAGKDGLMYAASKGLGIVIMEPMRGGYLVSGMPPEIQEIWDSADIQRSPVEWSLRY
CCCCCCCCCCEEEEECCCCEEEEECCCCCCEEECCCCHHHHHHHCCCCCCCCCHHEEHHH
LWDYPEIAVVLSGMSEIKHVEDNVKFASGGLPDSLTERERELISRVKKIYMSKTRVNCTG
HCCCHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
CRYCMPCPSGVNIPENFKYLNNAEMFDNAEGEKALYSGLEGQASNCTECGQCEEKCPQKI
CCEECCCCCCCCCCCCCHHCCCCHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCC
PVSQMLKEVVKLFGK
CHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]