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The map label for this gene is katE [H]

Identifier: 21228052

GI number: 21228052

Start: 2319473

End: 2321605

Strand: Direct

Name: katE [H]

Synonym: MM_1950

Alternate gene names: 21228052

Gene position: 2319473-2321605 (Clockwise)

Preceding gene: 21228050

Following gene: 21228054

Centisome position: 56.62

GC content: 45.85

Gene sequence:

>2133_bases
ATGGATAAAAAGATGATTAACGAAAAAAGCAAAGAGGAGCAGTTGGAAAAGTTTCATGAAGATCCGGAACGTGAGTTTTT
AACTACAAACCAGGGAGTCAGGGTAAATAATACGGACATCTCACTCAAAGCAGGAGAAAGAGGACCCACCCTTCTTGAGG
ACTTTCACTTCAGAGAAAAATTAACTCATTTTGACCATGAAAGAATTCCTGAAAGAGTCGTTCACGCCAGAGGCTCAGGT
GCACATGGTTTCTTCCAGGTATATGAACCCATGACAGAATATACAAGTGCGAAATTCCTGCAGGACCCTAATAAAAAAAC
CCCGGTTTTTGTTCGTTTTTCTACCGTTGTAGGGTTCAGGGGCTCGGCAGATACTGTCAGGGATGTCCGGGGTTTTGCTG
TTAAATTCTACACTGAGGACGGAAACTATGACCTTGTCGGCAACAACATGCCTGTTTTTTTCATTCAGGATGCAATAAAG
TTTCCCGACCTGGTTCATGCGATCAAGCCTGAGCAGGATAACCAGATTCCCCAGGCTTCTGCAGCGCATGATACTTTCTG
GGACTTTGTGTCATGTCACCATGAAAATGCGCATATGATCATGTGGGTTCTTTCAGACCGTGCACTTCCAAGAAGCTACC
GGATGATGGAGGGTTTTGGGGTTAACACCTTCCGTTTTGTCAATGCCGAAGGTAAGGGCAGGTTTATAAAATTCCACTGG
AAGCCCATGCTTGGAATTCATTCCCTTGTCTGGGACGAAACTCAGAAAATAGCAGGAAAAGACCCTGATTTTAACCGTCG
TGATCTCTGGGATGCCATTGAGATGGGAGCCTATCCTGAGTTTGAGTTAGGGGTGCAGATCCTGGAGGAAGAGGATGAAT
TCAAATTTGACTTTGATATTCTCGACCCTACAAAGTTATGGCCGGAAGAGGATGTACCAATAAAATGGATAGGGAAAATG
ACCCTGGACCGCAACCCTGATAATTTCTTTGCTGAGACCGAGCAGGTTGCGTTTTGCCCTGCGAATGTGGTTCCGGGAAT
TGACTTTTCCAATGACCCTCTCCTGCAGGGACGGCTTTTCTCGTATCTTGATACACAACTGATCCGCCTTGGAGGTCCTA
ACTTCCAGGAGATTCCAGTTAATCGAGCGCTAGCACCGGTGGCTAACAATCAGAGGGAAGGATATAACCGTATGACAATA
AACAAGGGCAAAACGAGTTATTTCCCGAATACTGTAGGAGATGGCAAGCCAAGGCCAGCTTCTGCAGAAGAAGGCGGTTA
TGTCCATTATATGGAAAAAGTGGAAGGCAAGATAATCCGTTCCCGCAGCGAAAAGTTCAAAGATTTTTTCAGCCAGGCAA
AATTATTCTGGAACAGCATGTCGCAACCTGAAAAAGAACATATTATAGAGGCTTTCCATTTCGAAATAGGAAAGGTCAAG
GACAAGAAAATCAGGCAGGCAGTTGTTGATATGTTCAATAACGTCGATGGTGACCTGGCAGTAGAGATTGCAAAGGGGGT
CGGTGTCTCTGCTCCGGCACAGAAAGGAGGTTCTCCTGTAGCTAAAGAATCGCCAAATTTGAGCCAGGAACGCAGTGAAC
GTAATGTGAAAAATACTATCAAAACCAGGAAAATCGCCATCATTGTCGCGGACGGATATGACCACAAAGACCTGAGCCAG
GTAATGCAGGCTCTGGAAGCCGGTGGAGCAAGAGCCGACATTATCTCAAAATTCCAGGGCATGCTGAAGAGCTCGGACGG
TCAGGAAATTGAAGTTGACAAAAATTACCGCACTACAGAATCGGTTCTGTATGATGCTGTATACATCCCCGGAGGAAAAG
AAAATGTGGAAACCCTGAAAAAGCATGGGGATGCTATCCACTTCGTCAATGAAGCTTTCAGGCACTGCAAGCCTCTGGGT
GCAACAGGCGAAGGAGTCGAATTATTTAAAGCTGCCCATCTTCCGGATATAAAACTCGCAGGAAAGAGTTCTGCTGATAA
GGTGGTTTCCGATAAAGGGGTGGTGACCGCCAGAAATGAAGGGGACAGAAGCTCTTTTAATGAGTCTTTTACCATCGCAA
TTGCACAGCACCGCCACTGGAACAGGGAGAAAAAGGAACAGGTTCCTGCCTGA

Upstream 100 bases:

>100_bases
ACCTGAATCGTAGATAGTCCATGCTTATTGAATTCTTGTATAAACTATGGGCTCCAGCACCGAATAATCTGGACTATATA
AACTGGGAGGATAACTGTAT

Downstream 100 bases:

>100_bases
ACTCTTTAAGGAAGAGTTCTCCGGCTTTATTTTTTAACCGTTTCTCTCTTTTTTCTTCCTCTTTAATTCTATTTTTAATC
TTTTTATTTTACTTCCTTTT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 710; Mature: 710

Protein sequence:

>710_residues
MDKKMINEKSKEEQLEKFHEDPEREFLTTNQGVRVNNTDISLKAGERGPTLLEDFHFREKLTHFDHERIPERVVHARGSG
AHGFFQVYEPMTEYTSAKFLQDPNKKTPVFVRFSTVVGFRGSADTVRDVRGFAVKFYTEDGNYDLVGNNMPVFFIQDAIK
FPDLVHAIKPEQDNQIPQASAAHDTFWDFVSCHHENAHMIMWVLSDRALPRSYRMMEGFGVNTFRFVNAEGKGRFIKFHW
KPMLGIHSLVWDETQKIAGKDPDFNRRDLWDAIEMGAYPEFELGVQILEEEDEFKFDFDILDPTKLWPEEDVPIKWIGKM
TLDRNPDNFFAETEQVAFCPANVVPGIDFSNDPLLQGRLFSYLDTQLIRLGGPNFQEIPVNRALAPVANNQREGYNRMTI
NKGKTSYFPNTVGDGKPRPASAEEGGYVHYMEKVEGKIIRSRSEKFKDFFSQAKLFWNSMSQPEKEHIIEAFHFEIGKVK
DKKIRQAVVDMFNNVDGDLAVEIAKGVGVSAPAQKGGSPVAKESPNLSQERSERNVKNTIKTRKIAIIVADGYDHKDLSQ
VMQALEAGGARADIISKFQGMLKSSDGQEIEVDKNYRTTESVLYDAVYIPGGKENVETLKKHGDAIHFVNEAFRHCKPLG
ATGEGVELFKAAHLPDIKLAGKSSADKVVSDKGVVTARNEGDRSSFNESFTIAIAQHRHWNREKKEQVPA

Sequences:

>Translated_710_residues
MDKKMINEKSKEEQLEKFHEDPEREFLTTNQGVRVNNTDISLKAGERGPTLLEDFHFREKLTHFDHERIPERVVHARGSG
AHGFFQVYEPMTEYTSAKFLQDPNKKTPVFVRFSTVVGFRGSADTVRDVRGFAVKFYTEDGNYDLVGNNMPVFFIQDAIK
FPDLVHAIKPEQDNQIPQASAAHDTFWDFVSCHHENAHMIMWVLSDRALPRSYRMMEGFGVNTFRFVNAEGKGRFIKFHW
KPMLGIHSLVWDETQKIAGKDPDFNRRDLWDAIEMGAYPEFELGVQILEEEDEFKFDFDILDPTKLWPEEDVPIKWIGKM
TLDRNPDNFFAETEQVAFCPANVVPGIDFSNDPLLQGRLFSYLDTQLIRLGGPNFQEIPVNRALAPVANNQREGYNRMTI
NKGKTSYFPNTVGDGKPRPASAEEGGYVHYMEKVEGKIIRSRSEKFKDFFSQAKLFWNSMSQPEKEHIIEAFHFEIGKVK
DKKIRQAVVDMFNNVDGDLAVEIAKGVGVSAPAQKGGSPVAKESPNLSQERSERNVKNTIKTRKIAIIVADGYDHKDLSQ
VMQALEAGGARADIISKFQGMLKSSDGQEIEVDKNYRTTESVLYDAVYIPGGKENVETLKKHGDAIHFVNEAFRHCKPLG
ATGEGVELFKAAHLPDIKLAGKSSADKVVSDKGVVTARNEGDRSSFNESFTIAIAQHRHWNREKKEQVPA
>Mature_710_residues
MDKKMINEKSKEEQLEKFHEDPEREFLTTNQGVRVNNTDISLKAGERGPTLLEDFHFREKLTHFDHERIPERVVHARGSG
AHGFFQVYEPMTEYTSAKFLQDPNKKTPVFVRFSTVVGFRGSADTVRDVRGFAVKFYTEDGNYDLVGNNMPVFFIQDAIK
FPDLVHAIKPEQDNQIPQASAAHDTFWDFVSCHHENAHMIMWVLSDRALPRSYRMMEGFGVNTFRFVNAEGKGRFIKFHW
KPMLGIHSLVWDETQKIAGKDPDFNRRDLWDAIEMGAYPEFELGVQILEEEDEFKFDFDILDPTKLWPEEDVPIKWIGKM
TLDRNPDNFFAETEQVAFCPANVVPGIDFSNDPLLQGRLFSYLDTQLIRLGGPNFQEIPVNRALAPVANNQREGYNRMTI
NKGKTSYFPNTVGDGKPRPASAEEGGYVHYMEKVEGKIIRSRSEKFKDFFSQAKLFWNSMSQPEKEHIIEAFHFEIGKVK
DKKIRQAVVDMFNNVDGDLAVEIAKGVGVSAPAQKGGSPVAKESPNLSQERSERNVKNTIKTRKIAIIVADGYDHKDLSQ
VMQALEAGGARADIISKFQGMLKSSDGQEIEVDKNYRTTESVLYDAVYIPGGKENVETLKKHGDAIHFVNEAFRHCKPLG
ATGEGVELFKAAHLPDIKLAGKSSADKVVSDKGVVTARNEGDRSSFNESFTIAIAQHRHWNREKKEQVPA

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=484, Percent_Identity=42.1487603305785, Blast_Score=370, Evalue=1e-102,
Organism=Escherichia coli, GI48994891, Length=712, Percent_Identity=50.7022471910112, Blast_Score=714, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71998444, Length=503, Percent_Identity=40.7554671968191, Blast_Score=383, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI25147792, Length=501, Percent_Identity=40.5189620758483, Blast_Score=370, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI25151141, Length=494, Percent_Identity=40.6882591093117, Blast_Score=370, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6320462, Length=491, Percent_Identity=37.6782077393075, Blast_Score=316, Evalue=7e-87,
Organism=Saccharomyces cerevisiae, GI6321525, Length=336, Percent_Identity=43.1547619047619, Blast_Score=289, Evalue=1e-78,
Organism=Drosophila melanogaster, GI17981717, Length=433, Percent_Identity=43.8799076212471, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI19920968, Length=499, Percent_Identity=38.6773547094188, Blast_Score=352, Evalue=5e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614
- InterPro:   IPR002818 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel; PF01965 DJ-1_PfpI [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 80579; Mature: 80579

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKMINEKSKEEQLEKFHEDPEREFLTTNQGVRVNNTDISLKAGERGPTLLEDFHFREK
CCCHHHCCHHHHHHHHHHHCCCCHHHEECCCCEEECCCEEEEECCCCCCHHHHHHHHHHH
LTHFDHERIPERVVHARGSGAHGFFQVYEPMTEYTSAKFLQDPNKKTPVFVRFSTVVGFR
HHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECC
GSADTVRDVRGFAVKFYTEDGNYDLVGNNMPVFFIQDAIKFPDLVHAIKPEQDNQIPQAS
CCCHHHHHCCCEEEEEEEECCCEEEECCCCCEEEECCHHCCHHHHHHCCCCCCCCCCCCC
AAHDTFWDFVSCHHENAHMIMWVLSDRALPRSYRMMEGFGVNTFRFVNAEGKGRFIKFHW
CCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCEEEEEC
KPMLGIHSLVWDETQKIAGKDPDFNRRDLWDAIEMGAYPEFELGVQILEEEDEFKFDFDI
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHCHHEECCCCCCEEEEEE
LDPTKLWPEEDVPIKWIGKMTLDRNPDNFFAETEQVAFCPANVVPGIDFSNDPLLQGRLF
CCCHHCCCCCCCCEEEEEEEEECCCCCHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHH
SYLDTQLIRLGGPNFQEIPVNRALAPVANNQREGYNRMTINKGKTSYFPNTVGDGKPRPA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCC
SAEEGGYVHYMEKVEGKIIRSRSEKFKDFFSQAKLFWNSMSQPEKEHIIEAFHFEIGKVK
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
DKKIRQAVVDMFNNVDGDLAVEIAKGVGVSAPAQKGGSPVAKESPNLSQERSERNVKNTI
HHHHHHHHHHHHHCCCCCEEEEEHHCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHH
KTRKIAIIVADGYDHKDLSQVMQALEAGGARADIISKFQGMLKSSDGQEIEVDKNYRTTE
CEEEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHH
SVLYDAVYIPGGKENVETLKKHGDAIHFVNEAFRHCKPLGATGEGVELFKAAHLPDIKLA
HHHEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEC
GKSSADKVVSDKGVVTARNEGDRSSFNESFTIAIAQHRHWNREKKEQVPA
CCCCHHHHHCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCC
>Mature Secondary Structure
MDKKMINEKSKEEQLEKFHEDPEREFLTTNQGVRVNNTDISLKAGERGPTLLEDFHFREK
CCCHHHCCHHHHHHHHHHHCCCCHHHEECCCCEEECCCEEEEECCCCCCHHHHHHHHHHH
LTHFDHERIPERVVHARGSGAHGFFQVYEPMTEYTSAKFLQDPNKKTPVFVRFSTVVGFR
HHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECC
GSADTVRDVRGFAVKFYTEDGNYDLVGNNMPVFFIQDAIKFPDLVHAIKPEQDNQIPQAS
CCCHHHHHCCCEEEEEEEECCCEEEECCCCCEEEECCHHCCHHHHHHCCCCCCCCCCCCC
AAHDTFWDFVSCHHENAHMIMWVLSDRALPRSYRMMEGFGVNTFRFVNAEGKGRFIKFHW
CCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCEEEEEC
KPMLGIHSLVWDETQKIAGKDPDFNRRDLWDAIEMGAYPEFELGVQILEEEDEFKFDFDI
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHCHHEECCCCCCEEEEEE
LDPTKLWPEEDVPIKWIGKMTLDRNPDNFFAETEQVAFCPANVVPGIDFSNDPLLQGRLF
CCCHHCCCCCCCCEEEEEEEEECCCCCHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHH
SYLDTQLIRLGGPNFQEIPVNRALAPVANNQREGYNRMTINKGKTSYFPNTVGDGKPRPA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCC
SAEEGGYVHYMEKVEGKIIRSRSEKFKDFFSQAKLFWNSMSQPEKEHIIEAFHFEIGKVK
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
DKKIRQAVVDMFNNVDGDLAVEIAKGVGVSAPAQKGGSPVAKESPNLSQERSERNVKNTI
HHHHHHHHHHHHHCCCCCEEEEEHHCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHH
KTRKIAIIVADGYDHKDLSQVMQALEAGGARADIISKFQGMLKSSDGQEIEVDKNYRTTE
CEEEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHH
SVLYDAVYIPGGKENVETLKKHGDAIHFVNEAFRHCKPLGATGEGVELFKAAHLPDIKLA
HHHEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEC
GKSSADKVVSDKGVVTARNEGDRSSFNESFTIAIAQHRHWNREKKEQVPA
CCCCHHHHHCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]