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The map label for this gene is pdtaS [H]

Identifier: 21228017

GI number: 21228017

Start: 2274419

End: 2276245

Strand: Direct

Name: pdtaS [H]

Synonym: MM_1915

Alternate gene names: 21228017

Gene position: 2274419-2276245 (Clockwise)

Preceding gene: 21228016

Following gene: 21228018

Centisome position: 55.52

GC content: 44.83

Gene sequence:

>1827_bases
GTGCAGAAAGAGAATCGGGAAAAACCTGAACCTTTCACCGCCACGGAAAGTAATGCCAGGTGGACGCGTGAAGAGGCAGA
TCTGAAATTTGACAGCAACAGCATACCTGAAGGTTTCTTTATTGGCCGGGATGTTGCGGAAGGCAGGTCTGAAGAAAGGA
AGATTCACAACAGTACTGAAAAGCGCACGAAACCTGAGATGGGGAATACTTTCTCTCCTGTTCCTGAGGTTGAGAACCTC
GAGCTTGCTGATATTATTGATGCCAGGGCGATTAAATCCCTCATGGATGACTTTAATAAGCTTATTCACATAACCTTTGC
CCTGGTCGATCTCAAAGGCAATATTCTTGTGAGTTCCGGATGGCAGGATATATGCACCAGGTTCCACAGGGTTCACCCAG
AAACCTGCAAGCACTGTATAGAAAGCGATACAAAACTATCCGCTGGCGTTCTCCCCGGACAATTTAAGCTGTACAGATGC
AGGAACAATATGTGGGACATAGCGACGCCTATTATGGTGGGCGGCCATCACATAGGCAATATCTTTTCAGGACAGTTCTT
TTTTGAGGACGAGTATGTTGATTATGGTTTTTTCCGGTCTCAGGCAAGAAAATACGGCTTCAATGAAGAAGAATACATGG
CAGCGCTGGAAAAAGTCCCGAGGCTGAGCAGGGAATCCGTGGAAGCAGAAATGACTTTCTTAACGAAGCTTGCCCATATG
ATCTCACAGTTAAGCTACAGCAATACCAGACTGGCTCACTCACTTGTGGAGAGGGACTCTTTTGTTAACGCATTGAGAGA
GAGCGAAAGAAGGTATCGCAACATCATAGAGACAGCCAGTGAAGGCATACTGATAATTGATTCTGAAGTCAGGATCAGCT
ACGCTAATAAGAAAATGACGGATATGCTCGGATGTCCTCTGGAAGAGGTTACTGGCAGAAAGATGTGCGACTTTGTCAGT
GAAGAGAGTAAGGATATTGTCAAACTGAACCAGAAAAGAAGGCGTCAGGGTATTAATGATAGCTATGAATTGAAACTGGT
ATGTAAGGACGGGTCATCCTTATGGGCGCTCGTAAATGCTAAATCCCTTTTTGATAAGGATGGGAAATTTATGGGCTCGA
TAAGCTTGCTAACCGACATCACCAAGCGAAAAGAGGCTGAAGAAGCCCTGGCGAATATCGAAGTTGCCCGCAAAAAGGAA
ATCCATCACAGAATTAAGAATAACCTGCAGGTAATCTCCTCCCTGCTCGATCTTCAGGCTGAAAAGTTCAATAACAGAGA
GGATATTAAGGATCTGGAAGTCCTCTCCGCTTTCAGGGAAAGTCAGGACAGAGTTAAATCAATGGCACTCATCCATGAGG
AACTGTACAGAGGTGGAGGGCTTGACACACTTAACTTTTCATCGTACATTGAAGAACTTGTCGAAAACCTTTTCCGGACA
TACAGGCTTGGAAATGACAATCTCAGATTAAACGTGACCCTTGAAGAAAACATCTTTTTTGATATGGATACCGCAGTCCC
GTTAGGGATTATTGTTAACGAGCTTGTTTCCAATTCCCTCAAACATGCGTTTACTGGAAATGAAGGGGAAATTCGCATCC
GGTTTTGCAGGGAAGAAAAGAACGATAAAACACAGGAATCCCTCTTCAGCCTGACAATTTCAGATAACGGAAAAGGGATC
CCTGATAATATAGAACTGGAAAACCCCGGAACACTTGGGCTGAAGCTGGTAGGTATCCTCGTCGATCAGCTGGATGGAAA
TCTGGAGCTTGGACGGGGACAGGGGACAGAATTCAGGATTTCTTTCAGGGTACTGGAGAAATCATAA

Upstream 100 bases:

>100_bases
GAATTATTCTGGGGTTTCAGAAACAAATAATGTCTAATTTATACCCCCCGGTAATTCTGAAGTTGTCAGGCCTACTCGCA
GACAATGGAAGGTTAAGGAA

Downstream 100 bases:

>100_bases
ACCCGTATGCCAGAAACAGTTGATTTTCAATGTGTCTACTCTTTTTTCGATATCTCTCAATATTCTCAATGTCTCTCAAT
ATTCTCAATGTCTCTCAATA

Product: sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 608; Mature: 608

Protein sequence:

>608_residues
MQKENREKPEPFTATESNARWTREEADLKFDSNSIPEGFFIGRDVAEGRSEERKIHNSTEKRTKPEMGNTFSPVPEVENL
ELADIIDARAIKSLMDDFNKLIHITFALVDLKGNILVSSGWQDICTRFHRVHPETCKHCIESDTKLSAGVLPGQFKLYRC
RNNMWDIATPIMVGGHHIGNIFSGQFFFEDEYVDYGFFRSQARKYGFNEEEYMAALEKVPRLSRESVEAEMTFLTKLAHM
ISQLSYSNTRLAHSLVERDSFVNALRESERRYRNIIETASEGILIIDSEVRISYANKKMTDMLGCPLEEVTGRKMCDFVS
EESKDIVKLNQKRRRQGINDSYELKLVCKDGSSLWALVNAKSLFDKDGKFMGSISLLTDITKRKEAEEALANIEVARKKE
IHHRIKNNLQVISSLLDLQAEKFNNREDIKDLEVLSAFRESQDRVKSMALIHEELYRGGGLDTLNFSSYIEELVENLFRT
YRLGNDNLRLNVTLEENIFFDMDTAVPLGIIVNELVSNSLKHAFTGNEGEIRIRFCREEKNDKTQESLFSLTISDNGKGI
PDNIELENPGTLGLKLVGILVDQLDGNLELGRGQGTEFRISFRVLEKS

Sequences:

>Translated_608_residues
MQKENREKPEPFTATESNARWTREEADLKFDSNSIPEGFFIGRDVAEGRSEERKIHNSTEKRTKPEMGNTFSPVPEVENL
ELADIIDARAIKSLMDDFNKLIHITFALVDLKGNILVSSGWQDICTRFHRVHPETCKHCIESDTKLSAGVLPGQFKLYRC
RNNMWDIATPIMVGGHHIGNIFSGQFFFEDEYVDYGFFRSQARKYGFNEEEYMAALEKVPRLSRESVEAEMTFLTKLAHM
ISQLSYSNTRLAHSLVERDSFVNALRESERRYRNIIETASEGILIIDSEVRISYANKKMTDMLGCPLEEVTGRKMCDFVS
EESKDIVKLNQKRRRQGINDSYELKLVCKDGSSLWALVNAKSLFDKDGKFMGSISLLTDITKRKEAEEALANIEVARKKE
IHHRIKNNLQVISSLLDLQAEKFNNREDIKDLEVLSAFRESQDRVKSMALIHEELYRGGGLDTLNFSSYIEELVENLFRT
YRLGNDNLRLNVTLEENIFFDMDTAVPLGIIVNELVSNSLKHAFTGNEGEIRIRFCREEKNDKTQESLFSLTISDNGKGI
PDNIELENPGTLGLKLVGILVDQLDGNLELGRGQGTEFRISFRVLEKS
>Mature_608_residues
MQKENREKPEPFTATESNARWTREEADLKFDSNSIPEGFFIGRDVAEGRSEERKIHNSTEKRTKPEMGNTFSPVPEVENL
ELADIIDARAIKSLMDDFNKLIHITFALVDLKGNILVSSGWQDICTRFHRVHPETCKHCIESDTKLSAGVLPGQFKLYRC
RNNMWDIATPIMVGGHHIGNIFSGQFFFEDEYVDYGFFRSQARKYGFNEEEYMAALEKVPRLSRESVEAEMTFLTKLAHM
ISQLSYSNTRLAHSLVERDSFVNALRESERRYRNIIETASEGILIIDSEVRISYANKKMTDMLGCPLEEVTGRKMCDFVS
EESKDIVKLNQKRRRQGINDSYELKLVCKDGSSLWALVNAKSLFDKDGKFMGSISLLTDITKRKEAEEALANIEVARKKE
IHHRIKNNLQVISSLLDLQAEKFNNREDIKDLEVLSAFRESQDRVKSMALIHEELYRGGGLDTLNFSSYIEELVENLFRT
YRLGNDNLRLNVTLEENIFFDMDTAVPLGIIVNELVSNSLKHAFTGNEGEIRIRFCREEKNDKTQESLFSLTISDNGKGI
PDNIELENPGTLGLKLVGILVDQLDGNLELGRGQGTEFRISFRVLEKS

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69537; Mature: 69537

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKENREKPEPFTATESNARWTREEADLKFDSNSIPEGFFIGRDVAEGRSEERKIHNSTE
CCCCCCCCCCCCCCCCCCCCCCHHHCCCEECCCCCCCCEEECCHHHHCCHHHHHHHCCHH
KRTKPEMGNTFSPVPEVENLELADIIDARAIKSLMDDFNKLIHITFALVDLKGNILVSSG
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECC
WQDICTRFHRVHPETCKHCIESDTKLSAGVLPGQFKLYRCRNNMWDIATPIMVGGHHIGN
HHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHEECCCHHCC
IFSGQFFFEDEYVDYGFFRSQARKYGFNEEEYMAALEKVPRLSRESVEAEMTFLTKLAHM
HHCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ISQLSYSNTRLAHSLVERDSFVNALRESERRYRNIIETASEGILIIDSEVRISYANKKMT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCHHH
DMLGCPLEEVTGRKMCDFVSEESKDIVKLNQKRRRQGINDSYELKLVCKDGSSLWALVNA
HHHCCCHHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEH
KSLFDKDGKFMGSISLLTDITKRKEAEEALANIEVARKKEIHHRIKNNLQVISSLLDLQA
HHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKFNNREDIKDLEVLSAFRESQDRVKSMALIHEELYRGGGLDTLNFSSYIEELVENLFRT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
YRLGNDNLRLNVTLEENIFFDMDTAVPLGIIVNELVSNSLKHAFTGNEGEIRIRFCREEK
HCCCCCCEEEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
NDKTQESLFSLTISDNGKGIPDNIELENPGTLGLKLVGILVDQLDGNLELGRGQGTEFRI
CCHHHHHHEEEEECCCCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCEEECCCCCCEEEE
SFRVLEKS
EEEEECCC
>Mature Secondary Structure
MQKENREKPEPFTATESNARWTREEADLKFDSNSIPEGFFIGRDVAEGRSEERKIHNSTE
CCCCCCCCCCCCCCCCCCCCCCHHHCCCEECCCCCCCCEEECCHHHHCCHHHHHHHCCHH
KRTKPEMGNTFSPVPEVENLELADIIDARAIKSLMDDFNKLIHITFALVDLKGNILVSSG
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECC
WQDICTRFHRVHPETCKHCIESDTKLSAGVLPGQFKLYRCRNNMWDIATPIMVGGHHIGN
HHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHEECCCHHCC
IFSGQFFFEDEYVDYGFFRSQARKYGFNEEEYMAALEKVPRLSRESVEAEMTFLTKLAHM
HHCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ISQLSYSNTRLAHSLVERDSFVNALRESERRYRNIIETASEGILIIDSEVRISYANKKMT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCHHH
DMLGCPLEEVTGRKMCDFVSEESKDIVKLNQKRRRQGINDSYELKLVCKDGSSLWALVNA
HHHCCCHHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEH
KSLFDKDGKFMGSISLLTDITKRKEAEEALANIEVARKKEIHHRIKNNLQVISSLLDLQA
HHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKFNNREDIKDLEVLSAFRESQDRVKSMALIHEELYRGGGLDTLNFSSYIEELVENLFRT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
YRLGNDNLRLNVTLEENIFFDMDTAVPLGIIVNELVSNSLKHAFTGNEGEIRIRFCREEK
HCCCCCCEEEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
NDKTQESLFSLTISDNGKGIPDNIELENPGTLGLKLVGILVDQLDGNLELGRGQGTEFRI
CCHHHHHHEEEEECCCCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCEEECCCCCCEEEE
SFRVLEKS
EEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]