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The map label for this gene is fixC [C]

Identifier: 21227951

GI number: 21227951

Start: 2199907

End: 2201115

Strand: Direct

Name: fixC [C]

Synonym: MM_1849

Alternate gene names: 21227951

Gene position: 2199907-2201115 (Clockwise)

Preceding gene: 21227950

Following gene: 21227952

Centisome position: 53.7

GC content: 43.26

Gene sequence:

>1209_bases
ATGGCATGCTTCTCATCTTTAAGCACAGGTGTTCTGGATATGTATGATCTCATTATAGTAGGTGGAGGGCCTTCGGGAGC
TTCTGCTGGAAGAGTAGCCGGAAAAGCAGGAATTTCAACCCTCCTGATTGAAAAAGAAAATTTCCCGAGGTATAAGCCCT
GCGGAGGAGCTCTATCTCCTTACGCGCTTTCGTGCCTGGATTTCAAACTTCCTGAGTATTTGATCGAAAAGGATATTTCA
AGGATAAGGGTTCATTTCAGGGAGCTCTGCACTGAAATGCAAAAAGATTATTCAATAGCTTTGCTGGTCTCAAGAAAAGC
TTTTGACAATTTCCTGCTTGATAAAGCAAGAGAAACCGGCATTGACATTCATTCTGGGGAAAAAGTGCTTGATTGTGAGG
AAGGAGAAGAGTGCGTTGAGGTTAGAACTTCTCAGAACACTTACCTTGCAAAGTTTGTCCTTATTGCGGAAGGATCTGAA
GGCGTGCTTAAATACAGTGTCAGGAAGCGTAAAGACCGGAGAACGGAATATGACCTTGCCCTTGTTTCCGAAATTCCTGA
AAGGGATAAAGTAATAAGAAAGCGTTTTCCAAATGCGATAGATATGCATTTCGGAATCGCATCCGGAGGGTATGGCTGGA
TTTTTCCCCATTCCGAACACTATTCTGTGGGAATCGTGGGAACAGCCGAGCATCTTAAGCACCCGAAGGCTGTTATGCAG
GACTTTTTACAGGCAAATGGCTTTTCAGGAGATTTTCAGGTCCATTCTCACATTATCCCGGTTGGAGGAATTAAAAGAAA
AACCATAAGTTCAAGGATTCTTCTGAGCGGGGATGCAGCAGGTTTTGTGGACGCCTTCATAGGGGAAGGCATCTCATATG
CTATTCGCTCAGGGCAGCTTGCAGCGGAAAATGTAGCCGAAATCGTACTTTATAACCGGAAACTGAGCGACCTTAAAGAG
TATGAAACCAGCTGCAGGAAAGAGTTCGGTAATTTCCTCTCCAGTTCCCTTAAACTTGAAAAAGCCATGCACCGTTTCCC
TGAGACTTCTTTCAGGCTTGCTCTTAGCAGGAAGGAAATTATTGATAAATATCTGGAGGAGGTTGTAATAAATAGAAGCC
ACAAAGATTATGTCAGGTGGTTGCTGCTCAATTTCAGCCTTTCTGAACCTGCATCTAAAATAAAGTCCATTAAGGATAAA
AATCAGTAA

Upstream 100 bases:

>100_bases
TTATCAGGTTTTTTCCTGATTTTTTCTTTTCCCTTATCTTTTTATTTTTCCACGCCAATCTACTTTGTGAGGTATATCGT
CCGTTTGATGCTGTCTATGA

Downstream 100 bases:

>100_bases
TTTAGAGGCATTAAATCAAAAATTAATTAAAAAACAGGTTGAATGATAACTTTTGAAAAAAGAATGATAACTTTTGAAAA
AAACATGAGCATAAAAAGGA

Product: geranylgeranyl reductase

Products: NA

Alternate protein names: ORF3 [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MACFSSLSTGVLDMYDLIIVGGGPSGASAGRVAGKAGISTLLIEKENFPRYKPCGGALSPYALSCLDFKLPEYLIEKDIS
RIRVHFRELCTEMQKDYSIALLVSRKAFDNFLLDKARETGIDIHSGEKVLDCEEGEECVEVRTSQNTYLAKFVLIAEGSE
GVLKYSVRKRKDRRTEYDLALVSEIPERDKVIRKRFPNAIDMHFGIASGGYGWIFPHSEHYSVGIVGTAEHLKHPKAVMQ
DFLQANGFSGDFQVHSHIIPVGGIKRKTISSRILLSGDAAGFVDAFIGEGISYAIRSGQLAAENVAEIVLYNRKLSDLKE
YETSCRKEFGNFLSSSLKLEKAMHRFPETSFRLALSRKEIIDKYLEEVVINRSHKDYVRWLLLNFSLSEPASKIKSIKDK
NQ

Sequences:

>Translated_402_residues
MACFSSLSTGVLDMYDLIIVGGGPSGASAGRVAGKAGISTLLIEKENFPRYKPCGGALSPYALSCLDFKLPEYLIEKDIS
RIRVHFRELCTEMQKDYSIALLVSRKAFDNFLLDKARETGIDIHSGEKVLDCEEGEECVEVRTSQNTYLAKFVLIAEGSE
GVLKYSVRKRKDRRTEYDLALVSEIPERDKVIRKRFPNAIDMHFGIASGGYGWIFPHSEHYSVGIVGTAEHLKHPKAVMQ
DFLQANGFSGDFQVHSHIIPVGGIKRKTISSRILLSGDAAGFVDAFIGEGISYAIRSGQLAAENVAEIVLYNRKLSDLKE
YETSCRKEFGNFLSSSLKLEKAMHRFPETSFRLALSRKEIIDKYLEEVVINRSHKDYVRWLLLNFSLSEPASKIKSIKDK
NQ
>Mature_401_residues
ACFSSLSTGVLDMYDLIIVGGGPSGASAGRVAGKAGISTLLIEKENFPRYKPCGGALSPYALSCLDFKLPEYLIEKDISR
IRVHFRELCTEMQKDYSIALLVSRKAFDNFLLDKARETGIDIHSGEKVLDCEEGEECVEVRTSQNTYLAKFVLIAEGSEG
VLKYSVRKRKDRRTEYDLALVSEIPERDKVIRKRFPNAIDMHFGIASGGYGWIFPHSEHYSVGIVGTAEHLKHPKAVMQD
FLQANGFSGDFQVHSHIIPVGGIKRKTISSRILLSGDAAGFVDAFIGEGISYAIRSGQLAAENVAEIVLYNRKLSDLKEY
ETSCRKEFGNFLSSSLKLEKAMHRFPETSFRLALSRKEIIDKYLEEVVINRSHKDYVRWLLLNFSLSEPASKIKSIKDKN
Q

Specific function: Probably Accepts Electrons From Fixa/Fixb And Reduces A Quinone. [C]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. ChlP subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786227, Length=307, Percent_Identity=27.6872964169381, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011777
- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: NA

Molecular weight: Translated: 45024; Mature: 44893

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACFSSLSTGVLDMYDLIIVGGGPSGASAGRVAGKAGISTLLIEKENFPRYKPCGGALSP
CCCHHHHHHHHHEEEEEEEECCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCCCCCH
YALSCLDFKLPEYLIEKDISRIRVHFRELCTEMQKDYSIALLVSRKAFDNFLLDKARETG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHCC
IDIHSGEKVLDCEEGEECVEVRTSQNTYLAKFVLIAEGSEGVLKYSVRKRKDRRTEYDLA
CEECCCCEEECCCCCHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHH
LVSEIPERDKVIRKRFPNAIDMHFGIASGGYGWIFPHSEHYSVGIVGTAEHLKHPKAVMQ
HHHHCCHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCEEEEEEECHHHHCCCHHHHH
DFLQANGFSGDFQVHSHIIPVGGIKRKTISSRILLSGDAAGFVDAFIGEGISYAIRSGQL
HHHHHCCCCCCEEEEEEEEECCCCCHHHHCCEEEECCCCHHHHHHHHCCCHHHHHHCCCH
AAENVAEIVLYNRKLSDLKEYETSCRKEFGNFLSSSLKLEKAMHRFPETSFRLALSRKEI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IDKYLEEVVINRSHKDYVRWLLLNFSLSEPASKIKSIKDKNQ
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
ACFSSLSTGVLDMYDLIIVGGGPSGASAGRVAGKAGISTLLIEKENFPRYKPCGGALSP
CCHHHHHHHHHEEEEEEEECCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCCCCCH
YALSCLDFKLPEYLIEKDISRIRVHFRELCTEMQKDYSIALLVSRKAFDNFLLDKARETG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHCC
IDIHSGEKVLDCEEGEECVEVRTSQNTYLAKFVLIAEGSEGVLKYSVRKRKDRRTEYDLA
CEECCCCEEECCCCCHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHH
LVSEIPERDKVIRKRFPNAIDMHFGIASGGYGWIFPHSEHYSVGIVGTAEHLKHPKAVMQ
HHHHCCHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCEEEEEEECHHHHCCCHHHHH
DFLQANGFSGDFQVHSHIIPVGGIKRKTISSRILLSGDAAGFVDAFIGEGISYAIRSGQL
HHHHHCCCCCCEEEEEEEEECCCCCHHHHCCEEEECCCCHHHHHHHHCCCHHHHHHCCCH
AAENVAEIVLYNRKLSDLKEYETSCRKEFGNFLSSSLKLEKAMHRFPETSFRLALSRKEI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IDKYLEEVVINRSHKDYVRWLLLNFSLSEPASKIKSIKDKNQ
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a quinone or similar compound as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9063468 [H]