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The map label for this gene is pkn1 [H]

Identifier: 21227914

GI number: 21227914

Start: 2161400

End: 2162227

Strand: Direct

Name: pkn1 [H]

Synonym: MM_1812

Alternate gene names: 21227914

Gene position: 2161400-2162227 (Clockwise)

Preceding gene: 21227904

Following gene: 21227915

Centisome position: 52.76

GC content: 46.26

Gene sequence:

>828_bases
GTGGGAAGTAAAATCAGTATTATAAATCATATTAATACAATCCGATACTATCTGAAAAAGAACGAAGTTGAAGACAAAGT
TGAAGACCCTGCCGGTGCGGCAGAACCTGAAAGCACGGAAGCTTTTGGAACATTTATCAGTCCGTCTACAGGTATGGAAT
TCATAATGGCACCTGCCGGTGAATTTTTAATGGGTTCCTCTCCCGAGGAGAAAGGCAGGTCATACTCCGAATCTCCGGTC
CACAGGGTTACGATTAAAAATCCGTTTTACATCGGCAAATATCAGGTTACTCAAAAACAATGGAAAACTATAATGGGGAC
CAGTCCGTCGAATTTTAATGAAGATTTCCGTCCTGTTGAGCTGGTTTCCTGGGAAGATGTTCAGGAATTTATTGGAAAAC
TGAACGCAATGGAAAACACCACAAAATACCGCCTTCCTTCCGAAGCCGAGTGGGAGTATGCATGCAGAGCAGGTAAGCAG
AGCAGGTACTTTTTTGGTGAAGATGAATCCAAACTTGGCGACTATGCATGGTACGCCAGGAATGCAGGCCGTAAAACCCA
TCCTGCTGGCAGAAAAAAACCTAACCGCTGGGGCCTTTATGATATGTGCGGTAATGTCTGGGAATGGGTTCAGGACAGCT
GGCACGAAGACTATAATGGGGCTCCTTCTGACGGAAGCGCATGGGAAGACGGAAACAGCTCCAATCGTGTCTCTCGTGGG
GGAAGCTGGTACTGCTCTACCAATTCCTGCCGCTCAGCTTCCCGTTTCAGCCGTGAACCTGAGAAACATTTAGCCAACCT
TGGATTTCGGCTTGTGAAAGAGTTGTAA

Upstream 100 bases:

>100_bases
TAATATATATTATTTCCATATAATTATCCTTGTCAATGATTATGGGATCTGAGAACCTGTAGAACATAATGGAGAGTAAG
AACTTCTAGGGGTAAATTCT

Downstream 100 bases:

>100_bases
TTTTCTCTTCTTCTTTTTATATTCCTCAAAGACTTCTCTAACTGGTTTTTATCACTCAGCTTTCCCGGGTTCTTATCACT
ATCCTGACGCAACCCTCTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MGSKISIINHINTIRYYLKKNEVEDKVEDPAGAAEPESTEAFGTFISPSTGMEFIMAPAGEFLMGSSPEEKGRSYSESPV
HRVTIKNPFYIGKYQVTQKQWKTIMGTSPSNFNEDFRPVELVSWEDVQEFIGKLNAMENTTKYRLPSEAEWEYACRAGKQ
SRYFFGEDESKLGDYAWYARNAGRKTHPAGRKKPNRWGLYDMCGNVWEWVQDSWHEDYNGAPSDGSAWEDGNSSNRVSRG
GSWYCSTNSCRSASRFSREPEKHLANLGFRLVKEL

Sequences:

>Translated_275_residues
MGSKISIINHINTIRYYLKKNEVEDKVEDPAGAAEPESTEAFGTFISPSTGMEFIMAPAGEFLMGSSPEEKGRSYSESPV
HRVTIKNPFYIGKYQVTQKQWKTIMGTSPSNFNEDFRPVELVSWEDVQEFIGKLNAMENTTKYRLPSEAEWEYACRAGKQ
SRYFFGEDESKLGDYAWYARNAGRKTHPAGRKKPNRWGLYDMCGNVWEWVQDSWHEDYNGAPSDGSAWEDGNSSNRVSRG
GSWYCSTNSCRSASRFSREPEKHLANLGFRLVKEL
>Mature_274_residues
GSKISIINHINTIRYYLKKNEVEDKVEDPAGAAEPESTEAFGTFISPSTGMEFIMAPAGEFLMGSSPEEKGRSYSESPVH
RVTIKNPFYIGKYQVTQKQWKTIMGTSPSNFNEDFRPVELVSWEDVQEFIGKLNAMENTTKYRLPSEAEWEYACRAGKQS
RYFFGEDESKLGDYAWYARNAGRKTHPAGRKKPNRWGLYDMCGNVWEWVQDSWHEDYNGAPSDGSAWEDGNSSNRVSRGG
SWYCSTNSCRSASRFSREPEKHLANLGFRLVKEL

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=272, Percent_Identity=27.2058823529412, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI38202250, Length=297, Percent_Identity=25.2525252525253, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20130397, Length=198, Percent_Identity=32.8282828282828, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 31375; Mature: 31244

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSKISIINHINTIRYYLKKNEVEDKVEDPAGAAEPESTEAFGTFISPSTGMEFIMAPAG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCEEEECCCC
EFLMGSSPEEKGRSYSESPVHRVTIKNPFYIGKYQVTQKQWKTIMGTSPSNFNEDFRPVE
HHHCCCCCHHHCCCCCCCCCEEEEECCCEEECEEEHHHHHHHHHHCCCCCCCCCCCCCEE
LVSWEDVQEFIGKLNAMENTTKYRLPSEAEWEYACRAGKQSRYFFGEDESKLGDYAWYAR
EECHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHCCCCCCEECCCCCHHHHHHHHHHH
NAGRKTHPAGRKKPNRWGLYDMCGNVWEWVQDSWHEDYNGAPSDGSAWEDGNSSNRVSRG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
GSWYCSTNSCRSASRFSREPEKHLANLGFRLVKEL
CCEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GSKISIINHINTIRYYLKKNEVEDKVEDPAGAAEPESTEAFGTFISPSTGMEFIMAPAG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCEEEECCCC
EFLMGSSPEEKGRSYSESPVHRVTIKNPFYIGKYQVTQKQWKTIMGTSPSNFNEDFRPVE
HHHCCCCCHHHCCCCCCCCCEEEEECCCEEECEEEHHHHHHHHHHCCCCCCCCCCCCCEE
LVSWEDVQEFIGKLNAMENTTKYRLPSEAEWEYACRAGKQSRYFFGEDESKLGDYAWYAR
EECHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHCCCCCCEECCCCCHHHHHHHHHHH
NAGRKTHPAGRKKPNRWGLYDMCGNVWEWVQDSWHEDYNGAPSDGSAWEDGNSSNRVSRG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
GSWYCSTNSCRSASRFSREPEKHLANLGFRLVKEL
CCEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]