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The map label for this gene is yfdZ [C]

Identifier: 21227904

GI number: 21227904

Start: 2151057

End: 2152241

Strand: Direct

Name: yfdZ [C]

Synonym: MM_1802

Alternate gene names: 21227904

Gene position: 2151057-2152241 (Clockwise)

Preceding gene: 21227903

Following gene: 21227914

Centisome position: 52.51

GC content: 49.96

Gene sequence:

>1185_bases
ATGTTTTCGATAAACTCCGAATGCGTCATATCAAAAAAATCAGAGGATATCCCCCCTTTCTATGTGATGGAAGTCCTGGA
AAGTGCCCAGGCTCTGGAAGCTCAGGGCAGGCACATAATCCACCTCGAGGTAGGAGAGCCCGATTTTCCTACCGCTCCAC
ATATCTGTGAAGCCGCCTGCGCTGCTATTGGCAGGGGACTGACAAAGTACACTCATAGCCAGGGGTTGCTTGCTCTCAGA
GAGGCGATAGTTGAGTCTTATTATCAGAAGTTTGGAGTGGACCTGGACCCGGGTCAGGTTATCGTTACCTCGGGGACAAG
CCCGGCTCTCCTGATGGTTTTCATGGCTCTGCTTGAAAAGAGGGATGAAGTAATTATGTCTAACCCTCACTACTCCTGTT
ATCCGAATTTTGTAAAACACCTCGGCGGGACGCCTGTTTTTGTTTATACGAACGAAACAAACGGATTTGCCCTTGAGCCG
GAAACAGTAAGGCAGCGCCTGAGCCCCAATACGAAAGCTATCCTTATCAACAGCCCTTCAAATCCGGGAGGGCATGTTAT
GTCCCCTGAAAACCTGCAGGGACTTGCAGCGATAGCTGATGAACGGGGAATTCCTATCGTTTCTGACGAGATCTACCAGG
GCCTGATTTACAGCGGTGAAGAACACAGCATCCTTGAATACACAAAAAACGCCTTTGTCCTTAACGGGTTTTCCAAGCTG
TATGCGATGACAGGCTGGAGGTTGGGCTATATTATCTGTCCCCCCGGATGCGTGCGTGCACTTCAGAAGATTCACCAGAA
CTTCTTTATCTGCGCCAACTCTTTTGTGCAGGAGGCAGGAATCGCGGCCCTGAAAGGTCCTCAGGAACATGTCACTGAGA
TGGTCCAGACCTATAATGTGCGCCGGCAGTATATGCTGAAAAGGCTTATCGGTATGGGGCTTGATGTACGCAAAGAGCCA
ATGGGAGCTTTTTATGTCCTTGCTGATGCCCGAAAATACTGCAGTGACTCCCTTGAACTGAGCCGCAGGATACTCAATGA
GGCAGGTGTGGCTGTAACCCCGGGAATAGACTTCGGGAACGGGGCAGAGGGCTACCTGCGTTTTTCCTATGCCAACAGCC
TGGAAAATATTACAGAAGGAATGGACCGCCTGGAAGCTTTTCTGGAAAAAGAGCTTGAAGGGTAA

Upstream 100 bases:

>100_bases
TTAAATCTTGAAAGCATACGCAGTCTCAGGTACATACTCTGTGGTATTATTTGCTTCCAGCTTATGGCTTTTATAGTGAT
CATTTTTCAGAAGGTCTTTC

Downstream 100 bases:

>100_bases
GTTTTTCGGATCTGGCAGCGGACACTTTCTGTTTATTAATTTTTCTAATTTTTTCTAATTTTTTTCTAATTGTTTTTTTA
GTGCTCTTCTCGAATTGTTT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MFSINSECVISKKSEDIPPFYVMEVLESAQALEAQGRHIIHLEVGEPDFPTAPHICEAACAAIGRGLTKYTHSQGLLALR
EAIVESYYQKFGVDLDPGQVIVTSGTSPALLMVFMALLEKRDEVIMSNPHYSCYPNFVKHLGGTPVFVYTNETNGFALEP
ETVRQRLSPNTKAILINSPSNPGGHVMSPENLQGLAAIADERGIPIVSDEIYQGLIYSGEEHSILEYTKNAFVLNGFSKL
YAMTGWRLGYIICPPGCVRALQKIHQNFFICANSFVQEAGIAALKGPQEHVTEMVQTYNVRRQYMLKRLIGMGLDVRKEP
MGAFYVLADARKYCSDSLELSRRILNEAGVAVTPGIDFGNGAEGYLRFSYANSLENITEGMDRLEAFLEKELEG

Sequences:

>Translated_394_residues
MFSINSECVISKKSEDIPPFYVMEVLESAQALEAQGRHIIHLEVGEPDFPTAPHICEAACAAIGRGLTKYTHSQGLLALR
EAIVESYYQKFGVDLDPGQVIVTSGTSPALLMVFMALLEKRDEVIMSNPHYSCYPNFVKHLGGTPVFVYTNETNGFALEP
ETVRQRLSPNTKAILINSPSNPGGHVMSPENLQGLAAIADERGIPIVSDEIYQGLIYSGEEHSILEYTKNAFVLNGFSKL
YAMTGWRLGYIICPPGCVRALQKIHQNFFICANSFVQEAGIAALKGPQEHVTEMVQTYNVRRQYMLKRLIGMGLDVRKEP
MGAFYVLADARKYCSDSLELSRRILNEAGVAVTPGIDFGNGAEGYLRFSYANSLENITEGMDRLEAFLEKELEG
>Mature_394_residues
MFSINSECVISKKSEDIPPFYVMEVLESAQALEAQGRHIIHLEVGEPDFPTAPHICEAACAAIGRGLTKYTHSQGLLALR
EAIVESYYQKFGVDLDPGQVIVTSGTSPALLMVFMALLEKRDEVIMSNPHYSCYPNFVKHLGGTPVFVYTNETNGFALEP
ETVRQRLSPNTKAILINSPSNPGGHVMSPENLQGLAAIADERGIPIVSDEIYQGLIYSGEEHSILEYTKNAFVLNGFSKL
YAMTGWRLGYIICPPGCVRALQKIHQNFFICANSFVQEAGIAALKGPQEHVTEMVQTYNVRRQYMLKRLIGMGLDVRKEP
MGAFYVLADARKYCSDSLELSRRILNEAGVAVTPGIDFGNGAEGYLRFSYANSLENITEGMDRLEAFLEKELEG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=392, Percent_Identity=26.2755102040816, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI169881279, Length=392, Percent_Identity=26.2755102040816, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI56713254, Length=315, Percent_Identity=29.2063492063492, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI56713256, Length=321, Percent_Identity=28.9719626168224, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI169881281, Length=299, Percent_Identity=24.7491638795987, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4507369, Length=239, Percent_Identity=26.3598326359833, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI187936925, Length=358, Percent_Identity=24.0223463687151, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI14211921, Length=358, Percent_Identity=24.0223463687151, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI215599424, Length=380, Percent_Identity=22.6315789473684, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI19263340, Length=170, Percent_Identity=27.6470588235294, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788722, Length=387, Percent_Identity=29.9741602067183, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1786816, Length=359, Percent_Identity=26.4623955431755, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1788627, Length=383, Percent_Identity=26.6318537859008, Blast_Score=116, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=380, Percent_Identity=24.2105263157895, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=380, Percent_Identity=24.2105263157895, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=320, Percent_Identity=26.25, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17567663, Length=384, Percent_Identity=27.0833333333333, Blast_Score=96, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322401, Length=396, Percent_Identity=26.5151515151515, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28573069, Length=316, Percent_Identity=29.1139240506329, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646114, Length=316, Percent_Identity=29.1139240506329, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573067, Length=316, Percent_Identity=29.1139240506329, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573065, Length=316, Percent_Identity=29.1139240506329, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI18859735, Length=391, Percent_Identity=24.8081841432225, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24641770, Length=187, Percent_Identity=26.2032085561497, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641760, Length=187, Percent_Identity=26.2032085561497, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641768, Length=187, Percent_Identity=26.2032085561497, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641766, Length=187, Percent_Identity=26.2032085561497, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641764, Length=187, Percent_Identity=26.2032085561497, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI45551451, Length=187, Percent_Identity=26.2032085561497, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43578; Mature: 43578

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSINSECVISKKSEDIPPFYVMEVLESAQALEAQGRHIIHLEVGEPDFPTAPHICEAAC
CCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHH
AAIGRGLTKYTHSQGLLALREAIVESYYQKFGVDLDPGQVIVTSGTSPALLMVFMALLEK
HHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHC
RDEVIMSNPHYSCYPNFVKHLGGTPVFVYTNETNGFALEPETVRQRLSPNTKAILINSPS
CCCEEECCCCCCCCHHHHHHCCCCEEEEEECCCCCEEECHHHHHHHHCCCCCEEEEECCC
NPGGHVMSPENLQGLAAIADERGIPIVSDEIYQGLIYSGEEHSILEYTKNAFVLNGFSKL
CCCCCCCCCCCCCHHHHHHCCCCCCEECHHHHHHHHCCCCCCHHHHHHCCEEEECCHHHH
YAMTGWRLGYIICPPGCVRALQKIHQNFFICANSFVQEAGIAALKGPQEHVTEMVQTYNV
HHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHH
RRQYMLKRLIGMGLDVRKEPMGAFYVLADARKYCSDSLELSRRILNEAGVAVTPGIDFGN
HHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
GAEGYLRFSYANSLENITEGMDRLEAFLEKELEG
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFSINSECVISKKSEDIPPFYVMEVLESAQALEAQGRHIIHLEVGEPDFPTAPHICEAAC
CCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHH
AAIGRGLTKYTHSQGLLALREAIVESYYQKFGVDLDPGQVIVTSGTSPALLMVFMALLEK
HHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHC
RDEVIMSNPHYSCYPNFVKHLGGTPVFVYTNETNGFALEPETVRQRLSPNTKAILINSPS
CCCEEECCCCCCCCHHHHHHCCCCEEEEEECCCCCEEECHHHHHHHHCCCCCEEEEECCC
NPGGHVMSPENLQGLAAIADERGIPIVSDEIYQGLIYSGEEHSILEYTKNAFVLNGFSKL
CCCCCCCCCCCCCHHHHHHCCCCCCEECHHHHHHHHCCCCCCHHHHHHCCEEEECCHHHH
YAMTGWRLGYIICPPGCVRALQKIHQNFFICANSFVQEAGIAALKGPQEHVTEMVQTYNV
HHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHH
RRQYMLKRLIGMGLDVRKEPMGAFYVLADARKYCSDSLELSRRILNEAGVAVTPGIDFGN
HHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
GAEGYLRFSYANSLENITEGMDRLEAFLEKELEG
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]