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The map label for this gene is rpoN [H]

Identifier: 21227860

GI number: 21227860

Start: 2099440

End: 2099628

Strand: Direct

Name: rpoN [H]

Synonym: MM_1758

Alternate gene names: 21227860

Gene position: 2099440-2099628 (Clockwise)

Preceding gene: 21227859

Following gene: 21227861

Centisome position: 51.25

GC content: 49.74

Gene sequence:

>189_bases
ATGATCCCAGTCCGATGTTTCTCATGTGGAAAAGTAATCTCTAACTATTGGGATGAGTACAAAAGACGCGTCACCGATGG
CGAAGACGCTGCTGCAGTGCTGGATGATCTCGGGATCACCCGCTACTGCTGCCGCAGAATGTTCCTCAGCCATGTCGAAC
TTATTGACGTGCTTTCACCGTACCAGTAA

Upstream 100 bases:

>100_bases
GCAATTTACTTGTAAGCGATTCCAGGCAGAAAGAAGCCAAAAACTTTGGTGGACCTGGAGCTAGGTCTAAATATCAGAAA
TCTTACAGGTAAGGAAAGTT

Downstream 100 bases:

>100_bases
GGGACCGTAGGGTAGCTTGGTCCATCCTTCGGCGTTCGGGACGCCGGAACCTGAGTTCGAATCTCAGCGGTCCCATTTTC
CCTTTCAAGGGTACTGGTTT

Product: DNA-directed RNA polymerase subunit N

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 62; Mature: 62

Protein sequence:

>62_residues
MIPVRCFSCGKVISNYWDEYKRRVTDGEDAAAVLDDLGITRYCCRRMFLSHVELIDVLSPYQ

Sequences:

>Translated_62_residues
MIPVRCFSCGKVISNYWDEYKRRVTDGEDAAAVLDDLGITRYCCRRMFLSHVELIDVLSPYQ
>Mature_62_residues
MIPVRCFSCGKVISNYWDEYKRRVTDGEDAAAVLDDLGITRYCCRRMFLSHVELIDVLSPYQ

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG1644

COG function: function code K; DNA-directed RNA polymerase, subunit N (RpoN/RPB10)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal rpoN/eukaryotic RPB10 RNA polymerase subunit family [H]

Homologues:

Organism=Homo sapiens, GI10863925, Length=61, Percent_Identity=49.1803278688525, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17509857, Length=62, Percent_Identity=48.3870967741936, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324784, Length=63, Percent_Identity=47.6190476190476, Blast_Score=67, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24649759, Length=61, Percent_Identity=50.8196721311475, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012287
- InterPro:   IPR000268
- InterPro:   IPR020789
- ProDom:   PD006539 [H]

Pfam domain/function: PF01194 RNA_pol_N [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 7219; Mature: 7219

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS01112 RNA_POL_N_8KD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
9.7 %Cys+Met (Translated Protein)
6.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
9.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVRCFSCGKVISNYWDEYKRRVTDGEDAAAVLDDLGITRYCCRRMFLSHVELIDVLSP
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
YQ
CC
>Mature Secondary Structure
MIPVRCFSCGKVISNYWDEYKRRVTDGEDAAAVLDDLGITRYCCRRMFLSHVELIDVLSP
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
YQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]