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The map label for this gene is lysK [H]

Identifier: 21227798

GI number: 21227798

Start: 2038955

End: 2040577

Strand: Direct

Name: lysK [H]

Synonym: MM_1696

Alternate gene names: 21227798

Gene position: 2038955-2040577 (Clockwise)

Preceding gene: 21227797

Following gene: 21227799

Centisome position: 49.77

GC content: 48.61

Gene sequence:

>1623_bases
GTGATAAATATGGCTGACACAATTCACTGGGCAGACGTCATAGCCGAAGACGTGCTAAATAAGAGTGGCAAACACCTTGT
AGCCACTGGAATTACTCCCTCAGGGCATATCCATATAGGCAATATGAGAGAGGTAGTGACTGCCGATGCTGCTTATCGGG
CTCTTCTTGACAGAGGCGCAGATGCCCGCTTTATCTATATTGCTGACAATTTCGATCCCCTGCGTAAGGTTTATCCTTTC
CTTCCGGAGAGTTATGCCGAACATGTTGGAAAACCCATTTCTGAGGTTCCATGCCCCTGCGGGGAGTGTGCAAACTATTC
CGAGCACTTCCTGAAACCCTTCCTTGAAGCTCTAAGGCGCCTGGGCATCAACCCTGAGGTTTACAGGGCGGACGAAATGT
ACAGGGCAGGAATGTATACAGAAGCGATAAAGACAGCCCTTGTAAAAAGAAATGAAATTGCAAAGATCCTTGAAGAGGTC
TCAGGCAAAACCGTAGCAGAAGAATGGAGCCCCTTCAACCCGCGCTGTAACGAATGCGGAAAAATAACCACCACGAAGGT
TACAGGCTTTGACCCGGATGCCGAAACCGTGGACTATGTCTGTGCCTGCGGGCACTCGGGTACAGTCCCTATGGCAGGAG
GGGGAAAGCTCACCTGGAGAGTGGACTGGCCTGCCCGCTGGGCTGTACTTGGAGTAACTGTCGAGCCTTTTGGAAAAGAC
CATGCTTCAAGAGGTGGCTCTTATGACACAGGAAAGAGGATCGTCCGGGAAATCTACGGGCACGAACCTCCTTTCCCCAT
AGTCTACGAATGGATTATGCTGGGGAAGCAGGGGGCAATGTCTTCTTCTACAGGTGTGGTTGTCTCGATTTCTGATATGC
TCGAAGTAGTGCCTCCTGAAGTCCTGCGCTACCTTATCATCCGTACCAAGCCTGAAAAGCATATCCAGTTCGACCCCGCA
CAGCCTCTTCTTACCATAGTTGATGAATATGAACGCTTAAGGGAAAAGTTCAGGGATAATGATCCTTCCATGGGGGAGTT
TGAAAAGAGGATTTACGAGCTTTCCAGGGCTACCGGCATCTGCCACCCGGAAATTCCTTTCAAGCAGATGGTGACTATTT
TCCAGGTTGCCAGAGGAAATTTCGAGCAGATTCTCCAGATTGTGAAGCGTTCAGGCTTTTCAACTGAAGATGAAAAATGT
ATCCGGGAACTTGTGGACAACGTCTCAAAATGGCTCGAGCTTTATGCCCCTCCGTTCGCGAAATTTAGCGTAAAGGAAAA
TGTGCCCGTGCAGGTAGCAACCCTTTCCGAACTCCAGAAAGCCTTCCTCGGGGCATTTGCAGACCTTATTGAGTCAAAAG
GCAAAATCAGTGGAGAAGAATATCATATGCTGGTTTATTCTGCAAAAGAAAAAGGTTCCGAGCTTAACAGGCTGATTGCA
GAAAAATTGAATGTGCCTGCTCCTCAGGTAGATCCCAAAGATCTTTTCAAAGCGATTTACACCTCAATTCTCGGGCAGAG
CTCGGGACCTAAAGCTGGCTGGTTCCTTTCTTCCTTTGAAGAGGACTTCCTGATAAACAGATTCAGGGAAGCTTCTACTT
ACAGCCCTGAGAAGCGCGAATGA

Upstream 100 bases:

>100_bases
TAGTCGACACGATAATTATGCAGGAAACCTCCTGTAGATATATGCATGAACAGATCCTGATTTTTGTTTTCATACCTGAC
TCTACAGCTATCAAATTCTG

Downstream 100 bases:

>100_bases
AAACAGGGCAGGCGAATATGGAAACCGTGGATATGGGAGTAGAAAACTCAGGCATACAGGACATAAAGATTACAGATAAA
TCAACAGGGGAACTTGCAGG

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase 1; LysRS 1 [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MINMADTIHWADVIAEDVLNKSGKHLVATGITPSGHIHIGNMREVVTADAAYRALLDRGADARFIYIADNFDPLRKVYPF
LPESYAEHVGKPISEVPCPCGECANYSEHFLKPFLEALRRLGINPEVYRADEMYRAGMYTEAIKTALVKRNEIAKILEEV
SGKTVAEEWSPFNPRCNECGKITTTKVTGFDPDAETVDYVCACGHSGTVPMAGGGKLTWRVDWPARWAVLGVTVEPFGKD
HASRGGSYDTGKRIVREIYGHEPPFPIVYEWIMLGKQGAMSSSTGVVVSISDMLEVVPPEVLRYLIIRTKPEKHIQFDPA
QPLLTIVDEYERLREKFRDNDPSMGEFEKRIYELSRATGICHPEIPFKQMVTIFQVARGNFEQILQIVKRSGFSTEDEKC
IRELVDNVSKWLELYAPPFAKFSVKENVPVQVATLSELQKAFLGAFADLIESKGKISGEEYHMLVYSAKEKGSELNRLIA
EKLNVPAPQVDPKDLFKAIYTSILGQSSGPKAGWFLSSFEEDFLINRFREASTYSPEKRE

Sequences:

>Translated_540_residues
MINMADTIHWADVIAEDVLNKSGKHLVATGITPSGHIHIGNMREVVTADAAYRALLDRGADARFIYIADNFDPLRKVYPF
LPESYAEHVGKPISEVPCPCGECANYSEHFLKPFLEALRRLGINPEVYRADEMYRAGMYTEAIKTALVKRNEIAKILEEV
SGKTVAEEWSPFNPRCNECGKITTTKVTGFDPDAETVDYVCACGHSGTVPMAGGGKLTWRVDWPARWAVLGVTVEPFGKD
HASRGGSYDTGKRIVREIYGHEPPFPIVYEWIMLGKQGAMSSSTGVVVSISDMLEVVPPEVLRYLIIRTKPEKHIQFDPA
QPLLTIVDEYERLREKFRDNDPSMGEFEKRIYELSRATGICHPEIPFKQMVTIFQVARGNFEQILQIVKRSGFSTEDEKC
IRELVDNVSKWLELYAPPFAKFSVKENVPVQVATLSELQKAFLGAFADLIESKGKISGEEYHMLVYSAKEKGSELNRLIA
EKLNVPAPQVDPKDLFKAIYTSILGQSSGPKAGWFLSSFEEDFLINRFREASTYSPEKRE
>Mature_540_residues
MINMADTIHWADVIAEDVLNKSGKHLVATGITPSGHIHIGNMREVVTADAAYRALLDRGADARFIYIADNFDPLRKVYPF
LPESYAEHVGKPISEVPCPCGECANYSEHFLKPFLEALRRLGINPEVYRADEMYRAGMYTEAIKTALVKRNEIAKILEEV
SGKTVAEEWSPFNPRCNECGKITTTKVTGFDPDAETVDYVCACGHSGTVPMAGGGKLTWRVDWPARWAVLGVTVEPFGKD
HASRGGSYDTGKRIVREIYGHEPPFPIVYEWIMLGKQGAMSSSTGVVVSISDMLEVVPPEVLRYLIIRTKPEKHIQFDPA
QPLLTIVDEYERLREKFRDNDPSMGEFEKRIYELSRATGICHPEIPFKQMVTIFQVARGNFEQILQIVKRSGFSTEDEKC
IRELVDNVSKWLELYAPPFAKFSVKENVPVQVATLSELQKAFLGAFADLIESKGKISGEEYHMLVYSAKEKGSELNRLIA
EKLNVPAPQVDPKDLFKAIYTSILGQSSGPKAGWFLSSFEEDFLINRFREASTYSPEKRE

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 60692; Mature: 60692

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINMADTIHWADVIAEDVLNKSGKHLVATGITPSGHIHIGNMREVVTADAAYRALLDRGA
CCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHCCC
DARFIYIADNFDPLRKVYPFLPESYAEHVGKPISEVPCPCGECANYSEHFLKPFLEALRR
CEEEEEEECCCCHHHHHHCCCCHHHHHHCCCCHHHCCCCCHHHCCHHHHHHHHHHHHHHH
LGINPEVYRADEMYRAGMYTEAIKTALVKRNEIAKILEEVSGKTVAEEWSPFNPRCNECG
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHCCCCCCCCCCCC
KITTTKVTGFDPDAETVDYVCACGHSGTVPMAGGGKLTWRVDWPARWAVLGVTVEPFGKD
CEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCH
HASRGGSYDTGKRIVREIYGHEPPFPIVYEWIMLGKQGAMSSSTGVVVSISDMLEVVPPE
HHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHCCHH
VLRYLIIRTKPEKHIQFDPAQPLLTIVDEYERLREKFRDNDPSMGEFEKRIYELSRATGI
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
CHPEIPFKQMVTIFQVARGNFEQILQIVKRSGFSTEDEKCIRELVDNVSKWLELYAPPFA
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
KFSVKENVPVQVATLSELQKAFLGAFADLIESKGKISGEEYHMLVYSAKEKGSELNRLIA
CEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECHHCCHHHHHHHH
EKLNVPAPQVDPKDLFKAIYTSILGQSSGPKAGWFLSSFEEDFLINRFREASTYSPEKRE
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MINMADTIHWADVIAEDVLNKSGKHLVATGITPSGHIHIGNMREVVTADAAYRALLDRGA
CCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHCCC
DARFIYIADNFDPLRKVYPFLPESYAEHVGKPISEVPCPCGECANYSEHFLKPFLEALRR
CEEEEEEECCCCHHHHHHCCCCHHHHHHCCCCHHHCCCCCHHHCCHHHHHHHHHHHHHHH
LGINPEVYRADEMYRAGMYTEAIKTALVKRNEIAKILEEVSGKTVAEEWSPFNPRCNECG
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHCCCCCCCCCCCC
KITTTKVTGFDPDAETVDYVCACGHSGTVPMAGGGKLTWRVDWPARWAVLGVTVEPFGKD
CEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCH
HASRGGSYDTGKRIVREIYGHEPPFPIVYEWIMLGKQGAMSSSTGVVVSISDMLEVVPPE
HHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHCCHH
VLRYLIIRTKPEKHIQFDPAQPLLTIVDEYERLREKFRDNDPSMGEFEKRIYELSRATGI
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
CHPEIPFKQMVTIFQVARGNFEQILQIVKRSGFSTEDEKCIRELVDNVSKWLELYAPPFA
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
KFSVKENVPVQVATLSELQKAFLGAFADLIESKGKISGEEYHMLVYSAKEKGSELNRLIA
CEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECHHCCHHHHHHHH
EKLNVPAPQVDPKDLFKAIYTSILGQSSGPKAGWFLSSFEEDFLINRFREASTYSPEKRE
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]