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The map label for this gene is mtbB [H]

Identifier: 21227795

GI number: 21227795

Start: 2035616

End: 2036683

Strand: Direct

Name: mtbB [H]

Synonym: MM_1693

Alternate gene names: 21227795

Gene position: 2035616-2036683 (Clockwise)

Preceding gene: 21227794

Following gene: 21227796

Centisome position: 49.69

GC content: 53.37

Gene sequence:

>1068_bases
ATGGCAACCGAATATGCTTTAAGGATGGGAGACGGGAAACGGATCTTCCTTACTAAGGACAAGATCATAGAGGAGCTTGA
GGCAGGAATGGCGAATGCCTCTGACCTCGGTGAAATTCCCGACCTCAGCGGCGATGAAATCGACAAGCTTGCAGAAATTT
TGATGATGCCCGGCAAAGCCGTCAGTGTCGAGCAGGGCATGGAAGTCCCTGTCACACACGACATAGGCACATTAAGGCTT
GACGGTGACCAGGGCAACAGCGGTGTTGGTATACCTTCCAGCCGTCTTGTCGGGTGCATGATGCACGAAAGGGCATTTGG
CGCCGACACAATGGAACTGGGTCACATCGACTACAGCTACAAGCCTGTAAAGCCTGTCGTAGCAAACGAGTGCCAGGCAA
TGGAAGTCTGCCAGCAGAACATGATCATCCCTCTCTTTTACGGTGCAATGCCGAACATGGGGCTGTACTACACTCCTGAC
GGACCCTTCGAAAACCCCGGAGACCTCATGAAGGCTTTCAAGATCCAGGAAGCCTGGGACTCCATGGAACATGCAGCCGC
GCACCTTACAAGGGACACGGTCTGGGTTATGCAGAAACTCTTTGCCTCGGGAGCAGACGGCGTTAACTTTGACACCACCG
CTGCCGCAGGCGATGCTGACATGTACGGCACCCTCCATGCAATCGAAGCTCTTAGAAAGGAGTTCCCTGACATGTATATT
GAAGCAGGCATGGCTGGCGAATGCGTACTTGGTATGCACGGTAACCTCCAGTATGACGGGGTTACACTTGCAGGGCTCTG
GCCACACCAGCAGGCTCCTCTTATTGCAAAAGCAGGTGCAAACGTTTTCGGGCCTGTGTGCAACACCAACACAAGCAAGA
CCTCTCCATGGAACCTTGCACGCGCTGTCAACTTTATGAAAGCAGCAGTTCAGGCTTCTTCAATTCCCTGCCATGTTGAC
ATGGGCATGGGCGTCGGCGGAATTCCCATGCTTGAGACTCCTCCGATTGATGCCGTTACAAGGGCAAGCAAGGCAATGGT
CGAGATTGCAGGCGTAGACGGCATATAG

Upstream 100 bases:

>100_bases
GTGATTGCCCTGTGGCAGGCAAGGACTTTCGTGTCCAAATTCTGAACCAGGAATACAGCTTTCAGATCTAATACTAAAGC
AATATAAGTGGAGAATAAAA

Downstream 100 bases:

>100_bases
ATCGGGGTCGGCGACCCTCTGGGTATGCCGATCTCCCACATAATGGCCTCAGGCATGACAGGAATGAGAGCAGCAGGAGA
CCTTGTTGCAAGGATGCAGT

Product: dimethylamine:corrinoid methyltransferase

Products: NA

Alternate protein names: DMA methyltransferase 1; DMAMT 1 [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MATEYALRMGDGKRIFLTKDKIIEELEAGMANASDLGEIPDLSGDEIDKLAEILMMPGKAVSVEQGMEVPVTHDIGTLRL
DGDQGNSGVGIPSSRLVGCMMHERAFGADTMELGHIDYSYKPVKPVVANECQAMEVCQQNMIIPLFYGAMPNMGLYYTPD
GPFENPGDLMKAFKIQEAWDSMEHAAAHLTRDTVWVMQKLFASGADGVNFDTTAAAGDADMYGTLHAIEALRKEFPDMYI
EAGMAGECVLGMHGNLQYDGVTLAGLWPHQQAPLIAKAGANVFGPVCNTNTSKTSPWNLARAVNFMKAAVQASSIPCHVD
MGMGVGGIPMLETPPIDAVTRASKAMVEIAGVDGI

Sequences:

>Translated_355_residues
MATEYALRMGDGKRIFLTKDKIIEELEAGMANASDLGEIPDLSGDEIDKLAEILMMPGKAVSVEQGMEVPVTHDIGTLRL
DGDQGNSGVGIPSSRLVGCMMHERAFGADTMELGHIDYSYKPVKPVVANECQAMEVCQQNMIIPLFYGAMPNMGLYYTPD
GPFENPGDLMKAFKIQEAWDSMEHAAAHLTRDTVWVMQKLFASGADGVNFDTTAAAGDADMYGTLHAIEALRKEFPDMYI
EAGMAGECVLGMHGNLQYDGVTLAGLWPHQQAPLIAKAGANVFGPVCNTNTSKTSPWNLARAVNFMKAAVQASSIPCHVD
MGMGVGGIPMLETPPIDAVTRASKAMVEIAGVDGI
>Mature_354_residues
ATEYALRMGDGKRIFLTKDKIIEELEAGMANASDLGEIPDLSGDEIDKLAEILMMPGKAVSVEQGMEVPVTHDIGTLRLD
GDQGNSGVGIPSSRLVGCMMHERAFGADTMELGHIDYSYKPVKPVVANECQAMEVCQQNMIIPLFYGAMPNMGLYYTPDG
PFENPGDLMKAFKIQEAWDSMEHAAAHLTRDTVWVMQKLFASGADGVNFDTTAAAGDADMYGTLHAIEALRKEFPDMYIE
AGMAGECVLGMHGNLQYDGVTLAGLWPHQQAPLIAKAGANVFGPVCNTNTSKTSPWNLARAVNFMKAAVQASSIPCHVDM
GMGVGGIPMLETPPIDAVTRASKAMVEIAGVDGI

Specific function: Catalyzes the transfer of a methyl group from dimethylamine to the corrinoid cofactor of mtbC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dimethylamine methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012653 [H]

Pfam domain/function: PF09505 Dimeth_Pyl [H]

EC number: NA

Molecular weight: Translated: 38037; Mature: 37906

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEYALRMGDGKRIFLTKDKIIEELEAGMANASDLGEIPDLSGDEIDKLAEILMMPGKA
CCCCEEEEECCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
VSVEQGMEVPVTHDIGTLRLDGDQGNSGVGIPSSRLVGCMMHERAFGADTMELGHIDYSY
EEHHCCCCCCEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCC
KPVKPVVANECQAMEVCQQNMIIPLFYGAMPNMGLYYTPDGPFENPGDLMKAFKIQEAWD
CCCCCHHHCCHHHHHHHHHCCEEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHH
SMEHAAAHLTRDTVWVMQKLFASGADGVNFDTTAAAGDADMYGTLHAIEALRKEFPDMYI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHEE
EAGMAGECVLGMHGNLQYDGVTLAGLWPHQQAPLIAKAGANVFGPVCNTNTSKTSPWNLA
ECCCCCCEEEECCCCEEECCEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHH
RAVNFMKAAVQASSIPCHVDMGMGVGGIPMLETPPIDAVTRASKAMVEIAGVDGI
HHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCC
>Mature Secondary Structure 
ATEYALRMGDGKRIFLTKDKIIEELEAGMANASDLGEIPDLSGDEIDKLAEILMMPGKA
CCCEEEEECCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
VSVEQGMEVPVTHDIGTLRLDGDQGNSGVGIPSSRLVGCMMHERAFGADTMELGHIDYSY
EEHHCCCCCCEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCC
KPVKPVVANECQAMEVCQQNMIIPLFYGAMPNMGLYYTPDGPFENPGDLMKAFKIQEAWD
CCCCCHHHCCHHHHHHHHHCCEEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHH
SMEHAAAHLTRDTVWVMQKLFASGADGVNFDTTAAAGDADMYGTLHAIEALRKEFPDMYI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHEE
EAGMAGECVLGMHGNLQYDGVTLAGLWPHQQAPLIAKAGANVFGPVCNTNTSKTSPWNLA
ECCCCCCEEEECCCCEEECCEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHH
RAVNFMKAAVQASSIPCHVDMGMGVGGIPMLETPPIDAVTRASKAMVEIAGVDGI
HHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]