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The map label for this gene is mtbB [H]

Identifier: 21227796

GI number: 21227796

Start: 2036708

End: 2037019

Strand: Direct

Name: mtbB [H]

Synonym: MM_1694

Alternate gene names: 21227796

Gene position: 2036708-2037019 (Clockwise)

Preceding gene: 21227795

Following gene: 21227797

Centisome position: 49.72

GC content: 45.83

Gene sequence:

>312_bases
ATGCCGATCTCCCACATAATGGCCTCAGGCATGACAGGAATGAGAGCAGCAGGAGACCTTGTTGCAAGGATGCAGTTCTC
AAAGAACATGAAGATTAAAGAGGCAAAGGAATACGTTGCAAAGAAGCTAAATGTAGAAACCATGGACCTGGCGGATGAAT
ACGTTATGCGCGAACTCCGTGAGGAACTCGACATAGGCGTGATCACTTCAGTGCCTGGTGCTGCAAAGGGAATTGCCGCT
AAAATGAATATCGAGAAACTACTCGATGTAAAGATAAATTCCTGCAATCTCTTCAGGAAACAGACCCGGTAA

Upstream 100 bases:

>100_bases
TGAGACTCCTCCGATTGATGCCGTTACAAGGGCAAGCAAGGCAATGGTCGAGATTGCAGGCGTAGACGGCATATAGATCG
GGGTCGGCGACCCTCTGGGT

Downstream 100 bases:

>100_bases
AGAATAGATCAATTAAAAACGCTCAGTAAAACGGTCAATTTAAAAACAGTTGATTAAAAAACGGTTGATTAAAAAACGGT
TGATTAAAAAACGGTTGATT

Product: dimethylamine:corrinoid methyltransferase MtbB

Products: NA

Alternate protein names: DMA methyltransferase 1; DMAMT 1 [H]

Number of amino acids: Translated: 103; Mature: 102

Protein sequence:

>103_residues
MPISHIMASGMTGMRAAGDLVARMQFSKNMKIKEAKEYVAKKLNVETMDLADEYVMRELREELDIGVITSVPGAAKGIAA
KMNIEKLLDVKINSCNLFRKQTR

Sequences:

>Translated_103_residues
MPISHIMASGMTGMRAAGDLVARMQFSKNMKIKEAKEYVAKKLNVETMDLADEYVMRELREELDIGVITSVPGAAKGIAA
KMNIEKLLDVKINSCNLFRKQTR
>Mature_102_residues
PISHIMASGMTGMRAAGDLVARMQFSKNMKIKEAKEYVAKKLNVETMDLADEYVMRELREELDIGVITSVPGAAKGIAAK
MNIEKLLDVKINSCNLFRKQTR

Specific function: Catalyzes the transfer of a methyl group from dimethylamine to the corrinoid cofactor of mtbC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dimethylamine methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012653 [H]

Pfam domain/function: PF09505 Dimeth_Pyl [H]

EC number: NA

Molecular weight: Translated: 11505; Mature: 11374

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
8.7 %Met     (Translated Protein)
9.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
7.8 %Met     (Mature Protein)
8.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPISHIMASGMTGMRAAGDLVARMQFSKNMKIKEAKEYVAKKLNVETMDLADEYVMRELR
CCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EELDIGVITSVPGAAKGIAAKMNIEKLLDVKINSCNLFRKQTR
HHCCCCEECCCCCCCCCHHHHCCHHHHHHCCCCCCHHHHCCCC
>Mature Secondary Structure 
PISHIMASGMTGMRAAGDLVARMQFSKNMKIKEAKEYVAKKLNVETMDLADEYVMRELR
CHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EELDIGVITSVPGAAKGIAAKMNIEKLLDVKINSCNLFRKQTR
HHCCCCEECCCCCCCCCHHHHCCHHHHHHCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]