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The map label for this gene is cbiE [H]

Identifier: 21227782

GI number: 21227782

Start: 2017916

End: 2018503

Strand: Reverse

Name: cbiE [H]

Synonym: MM_1680

Alternate gene names: 21227782

Gene position: 2018503-2017916 (Counterclockwise)

Preceding gene: 21227783

Following gene: 21227781

Centisome position: 49.28

GC content: 47.96

Gene sequence:

>588_bases
ATGATAGTAGTAGGAGTTGGGGTCGGACCCGGCATGCTTACGGAAGAAGGAATAAGGGCAATAAAAAAGGCTTCGGCGGT
TTACGGTGCAAAAAGGGCGATTGAACTTGCACAGGAATACATCACCTGCGAAGCAAAAACGATTAAAGATTACAAGTCTC
TCCACCTCCTGCCCGCAGATGCAGTCATCCTGTCTACTGGAGACCCCATGTTTTCCGGTTTAGGGAAATTCGCAGGAGAA
AACGATACTGTAATTCCGGGAATTTCTTCAATGCAGGCAGCCTGTGCCCGCACGAAAGTGAACCTTACTAACCTCTGTGC
AATAACAGCCCACGGAAGGGATTTTGAACCTGCAAAAGCAGAATTGATCCAGGAATTAAGGAACGGAAGAAACATCTTCC
TGCTGCCGGAAGAGAATTTCGGCTCCCTTGAGGTTGCAAAAATCCTTAAAGAGCTCGGGATAGAAGCCGAGCTTTATACT
TGCGAAAACCTCGGCTATCCTGAAGAAAGGATTGCAAAGGGATCTCCTGACAACCCCCCGATCGCAGAAACCATTCTCTA
CGGGCTGCTCGTCGTGCAGAAAAGATAA

Upstream 100 bases:

>100_bases
AATCGTTGTAATTGACAGGGACGGGTCCGTCCTTATGGACAGTAAAAGTGAAAGTTAATGCTAAATGTTAAAATACAAGG
CAGGTAAAGGAGAAAAAGCC

Downstream 100 bases:

>100_bases
AAAACACACATGATATTCTTGGAATAACATGCCCAAAAAATGAAAGTCTTTTTCACTTAGCTTTTTTGATAATAGAACTC
CATCATTACCTTTGGACAGG

Product: cobalt-precorrin-6Y C(5)-methyltransferase

Products: S-adenosyl-L-homocysteine; Precorrin 8X; CO2

Alternate protein names: Cobalt-precorrin-6 methyltransferase; Cobalt-precorrin-6Y methylase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MIVVGVGVGPGMLTEEGIRAIKKASAVYGAKRAIELAQEYITCEAKTIKDYKSLHLLPADAVILSTGDPMFSGLGKFAGE
NDTVIPGISSMQAACARTKVNLTNLCAITAHGRDFEPAKAELIQELRNGRNIFLLPEENFGSLEVAKILKELGIEAELYT
CENLGYPEERIAKGSPDNPPIAETILYGLLVVQKR

Sequences:

>Translated_195_residues
MIVVGVGVGPGMLTEEGIRAIKKASAVYGAKRAIELAQEYITCEAKTIKDYKSLHLLPADAVILSTGDPMFSGLGKFAGE
NDTVIPGISSMQAACARTKVNLTNLCAITAHGRDFEPAKAELIQELRNGRNIFLLPEENFGSLEVAKILKELGIEAELYT
CENLGYPEERIAKGSPDNPPIAETILYGLLVVQKR
>Mature_195_residues
MIVVGVGVGPGMLTEEGIRAIKKASAVYGAKRAIELAQEYITCEAKTIKDYKSLHLLPADAVILSTGDPMFSGLGKFAGE
NDTVIPGISSMQAACARTKVNLTNLCAITAHGRDFEPAKAELIQELRNGRNIFLLPEENFGSLEVAKILKELGIEAELYT
CENLGYPEERIAKGSPDNPPIAETILYGLLVVQKR

Specific function: Probably catalyzes the methylation of C-5 in cobalt- precorrin-6Y to form cobalt-precorrin-7W-a [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR012818 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: 2.1.1.132

Molecular weight: Translated: 21019; Mature: 21019

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVGVGVGPGMLTEEGIRAIKKASAVYGAKRAIELAQEYITCEAKTIKDYKSLHLLPAD
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCCC
AVILSTGDPMFSGLGKFAGENDTVIPGISSMQAACARTKVNLTNLCAITAHGRDFEPAKA
EEEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHEEEEEECCCCCCHHHH
ELIQELRNGRNIFLLPEENFGSLEVAKILKELGIEAELYTCENLGYPEERIAKGSPDNPP
HHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHCCCCCCCCC
IAETILYGLLVVQKR
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MIVVGVGVGPGMLTEEGIRAIKKASAVYGAKRAIELAQEYITCEAKTIKDYKSLHLLPAD
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCCC
AVILSTGDPMFSGLGKFAGENDTVIPGISSMQAACARTKVNLTNLCAITAHGRDFEPAKA
EEEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHEEEEEECCCCCCHHHH
ELIQELRNGRNIFLLPEENFGSLEVAKILKELGIEAELYTCENLGYPEERIAKGSPDNPP
HHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHCCCCCCCCC
IAETILYGLLVVQKR
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-adenosyl-L-methionine; Precorrin 6Y

Specific reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]