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The map label for this gene is hsdM [C]

Identifier: 21227771

GI number: 21227771

Start: 1998423

End: 1999919

Strand: Direct

Name: hsdM [C]

Synonym: MM_1669

Alternate gene names: 21227771

Gene position: 1998423-1999919 (Clockwise)

Preceding gene: 21227770

Following gene: 21227773

Centisome position: 48.79

GC content: 49.7

Gene sequence:

>1497_bases
ATGTCTGAAAACACCTCATCCATCGTTTCCAAAGTCTGGAGCTTCTGCAACGTCCTCAGGGACGGGGGCGTGAGCTACGG
AGATTATCTGGAACAGTTGACCTACCTCATATTCCTTAAAATGGCGGAAGAATACAGGAAGCCGCCCTACAACAGAAATA
TCGGCATCCCCGAAGAATACACGTGGGACAGATTGAAACAGCAGCGAGGGGCAGAACTCGATACCCATTACAGGGAGCTT
CTCGAAGAGCTTGGGCAAAAGCCCGGGATGCTCGGGCAGATCTTCCTCAAATCCCAGAACAAGGTCAGCGACCCTGCCAT
GCTCTACAAGATCATTGATATGATCGACAAGGAAAGCTGGGTCATGATGGGTGTGGACACAAAAGGGGAAATCTACGAAG
GGCTCCTGCAAAAGAATGCCGAAGACACGAAAAGCGGAGCCGGGCAGTACTTCACTCCCAGGCCTCTTATTAAGGTTATG
GTGCAGTGCCTCCAGCCCGAACCCATGAAAACAATCGGAGACCCCTGCTGCGGCACAGGCGGGTTTTTTCTGGCAGCTTA
CGACTTCCTTACCTCGCACCACCGGCTGGACAGGGACCAGAGCCGCTTCCTGAAAAACAAAACTTTCGGGGGCAATGAAA
TCGTCGCAGGGACAAGACGGCTTGCCCTGATGAACATGTTCCTGCACAACATCGGGGAAATAGACGGGGAACCAATGATT
TCCAATTCCGATGCTCTCATAGCAGATCCAGGTTACCGTTACGATTACATCCTCACAAACCCGCCTTTCGGAAAAAAGAG
CAGCATGACCTTCACAAACGAAGAAGGCGAGCAGGAAAAAGAAGAACTCACTTACAACCGCCAGGACTTCTGGACAACCA
CAAGCAACAAGCAGCTCAACTTTTTGCAGCACATCCACACGATCCTCAAGACCGGTGGGCAGGCAGCAGTCGTTCTTCCT
GACAACGTTCTCTTTGAAGGCGGAGCAGGAGAGACCATTCGCAAGAAGCTTCTCGAAACCACAGACCTGCACACAATCCT
GCGCCTGCCGACAGGCATCTTCTATGCAAACGGCGTAAAAGCAAATGTGCTTTTCTTTGAAGCAAAACCCGCATCAAAAG
AGCCCTGGACAAAAGAAGTGTGGATCTACGACTACCGCACAAATGTGCACCACACATTGAAAAAGAACCCTCTGAAGTAT
TCCGACCTCGAAGATTTTATCAGATGCTACAACCCGGAAAACCGCTTCAATCGGAAAGAGACCTGGAGTGAAGAATCTCC
CGAGGGCAGGTTCAGGAAGTTCAGCTATGACGAAATAATAGCAAGGGACAAAACAAATCTGGACATTTTCTGGCTCAAGG
ACAAAAGCCTTGCTGACCTCGACAATCTCCCTGACCCGGATATTCTTGCAAACGAGATAATTGAGAATATGGAAGCTTCA
CTGGCAAGTTTCAAGGAGATTATGGCCACGATCAACGGAGAAAGTGAAGAGAATTAA

Upstream 100 bases:

>100_bases
ACCGAGCAAGTTACCGCGCAAGATGGCAATAGATATTGAAAATAAATTTTCTTAAGGAAGCAAAAACAAAAATATTACTC
TCATCTCAAGGATCCAAATC

Downstream 100 bases:

>100_bases
AATAAATTCCTCATCTGCCTGAAGGAAAAGATCAATATGTCTGAAGATTAAAAATGCTCTGATATTCTTTTTATCATCGC
CAGATCCGGAATTCATTTTT

Product: type I restriction-modification system specificity subunit

Products: NA

Alternate protein names: M.BthVORF4518P [H]

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MSENTSSIVSKVWSFCNVLRDGGVSYGDYLEQLTYLIFLKMAEEYRKPPYNRNIGIPEEYTWDRLKQQRGAELDTHYREL
LEELGQKPGMLGQIFLKSQNKVSDPAMLYKIIDMIDKESWVMMGVDTKGEIYEGLLQKNAEDTKSGAGQYFTPRPLIKVM
VQCLQPEPMKTIGDPCCGTGGFFLAAYDFLTSHHRLDRDQSRFLKNKTFGGNEIVAGTRRLALMNMFLHNIGEIDGEPMI
SNSDALIADPGYRYDYILTNPPFGKKSSMTFTNEEGEQEKEELTYNRQDFWTTTSNKQLNFLQHIHTILKTGGQAAVVLP
DNVLFEGGAGETIRKKLLETTDLHTILRLPTGIFYANGVKANVLFFEAKPASKEPWTKEVWIYDYRTNVHHTLKKNPLKY
SDLEDFIRCYNPENRFNRKETWSEESPEGRFRKFSYDEIIARDKTNLDIFWLKDKSLADLDNLPDPDILANEIIENMEAS
LASFKEIMATINGESEEN

Sequences:

>Translated_498_residues
MSENTSSIVSKVWSFCNVLRDGGVSYGDYLEQLTYLIFLKMAEEYRKPPYNRNIGIPEEYTWDRLKQQRGAELDTHYREL
LEELGQKPGMLGQIFLKSQNKVSDPAMLYKIIDMIDKESWVMMGVDTKGEIYEGLLQKNAEDTKSGAGQYFTPRPLIKVM
VQCLQPEPMKTIGDPCCGTGGFFLAAYDFLTSHHRLDRDQSRFLKNKTFGGNEIVAGTRRLALMNMFLHNIGEIDGEPMI
SNSDALIADPGYRYDYILTNPPFGKKSSMTFTNEEGEQEKEELTYNRQDFWTTTSNKQLNFLQHIHTILKTGGQAAVVLP
DNVLFEGGAGETIRKKLLETTDLHTILRLPTGIFYANGVKANVLFFEAKPASKEPWTKEVWIYDYRTNVHHTLKKNPLKY
SDLEDFIRCYNPENRFNRKETWSEESPEGRFRKFSYDEIIARDKTNLDIFWLKDKSLADLDNLPDPDILANEIIENMEAS
LASFKEIMATINGESEEN
>Mature_497_residues
SENTSSIVSKVWSFCNVLRDGGVSYGDYLEQLTYLIFLKMAEEYRKPPYNRNIGIPEEYTWDRLKQQRGAELDTHYRELL
EELGQKPGMLGQIFLKSQNKVSDPAMLYKIIDMIDKESWVMMGVDTKGEIYEGLLQKNAEDTKSGAGQYFTPRPLIKVMV
QCLQPEPMKTIGDPCCGTGGFFLAAYDFLTSHHRLDRDQSRFLKNKTFGGNEIVAGTRRLALMNMFLHNIGEIDGEPMIS
NSDALIADPGYRYDYILTNPPFGKKSSMTFTNEEGEQEKEELTYNRQDFWTTTSNKQLNFLQHIHTILKTGGQAAVVLPD
NVLFEGGAGETIRKKLLETTDLHTILRLPTGIFYANGVKANVLFFEAKPASKEPWTKEVWIYDYRTNVHHTLKKNPLKYS
DLEDFIRCYNPENRFNRKETWSEESPEGRFRKFSYDEIIARDKTNLDIFWLKDKSLADLDNLPDPDILANEIIENMEASL
ASFKEIMATINGESEEN

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=533, Percent_Identity=40.1500938086304, Blast_Score=352, Evalue=3e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 57230; Mature: 57099

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENTSSIVSKVWSFCNVLRDGGVSYGDYLEQLTYLIFLKMAEEYRKPPYNRNIGIPEEY
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
TWDRLKQQRGAELDTHYRELLEELGQKPGMLGQIFLKSQNKVSDPAMLYKIIDMIDKESW
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEHHEECCCCCCCCHHHHHHHHHHHCCCCE
VMMGVDTKGEIYEGLLQKNAEDTKSGAGQYFTPRPLIKVMVQCLQPEPMKTIGDPCCGTG
EEEECCCCHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCCCCC
GFFLAAYDFLTSHHRLDRDQSRFLKNKTFGGNEIVAGTRRLALMNMFLHNIGEIDGEPMI
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
SNSDALIADPGYRYDYILTNPPFGKKSSMTFTNEEGEQEKEELTYNRQDFWTTTSNKQLN
CCCCEEEECCCCCEEEEECCCCCCCCCCCEECCCCCHHHHHHHCCCCHHCEECCCCCHHH
FLQHIHTILKTGGQAAVVLPDNVLFEGGAGETIRKKLLETTDLHTILRLPTGIFYANGVK
HHHHHHHHHHCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCE
ANVLFFEAKPASKEPWTKEVWIYDYRTNVHHTLKKNPLKYSDLEDFIRCYNPENRFNRKE
EEEEEEECCCCCCCCCCCEEEEEEECCCHHHHHHCCCCCCCCHHHHHHHCCCHHHCCCHH
TWSEESPEGRFRKFSYDEIIARDKTNLDIFWLKDKSLADLDNLPDPDILANEIIENMEAS
CCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHH
LASFKEIMATINGESEEN
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SENTSSIVSKVWSFCNVLRDGGVSYGDYLEQLTYLIFLKMAEEYRKPPYNRNIGIPEEY
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
TWDRLKQQRGAELDTHYRELLEELGQKPGMLGQIFLKSQNKVSDPAMLYKIIDMIDKESW
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEHHEECCCCCCCCHHHHHHHHHHHCCCCE
VMMGVDTKGEIYEGLLQKNAEDTKSGAGQYFTPRPLIKVMVQCLQPEPMKTIGDPCCGTG
EEEECCCCHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCCCCC
GFFLAAYDFLTSHHRLDRDQSRFLKNKTFGGNEIVAGTRRLALMNMFLHNIGEIDGEPMI
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
SNSDALIADPGYRYDYILTNPPFGKKSSMTFTNEEGEQEKEELTYNRQDFWTTTSNKQLN
CCCCEEEECCCCCEEEEECCCCCCCCCCCEECCCCCHHHHHHHCCCCHHCEECCCCCHHH
FLQHIHTILKTGGQAAVVLPDNVLFEGGAGETIRKKLLETTDLHTILRLPTGIFYANGVK
HHHHHHHHHHCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCE
ANVLFFEAKPASKEPWTKEVWIYDYRTNVHHTLKKNPLKYSDLEDFIRCYNPENRFNRKE
EEEEEEECCCCCCCCCCCEEEEEEECCCHHHHHHCCCCCCCCHHHHHHHCCCHHHCCCHH
TWSEESPEGRFRKFSYDEIIARDKTNLDIFWLKDKSLADLDNLPDPDILANEIIENMEAS
CCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHH
LASFKEIMATINGESEEN
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]