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The map label for this gene is fmdB [H]

Identifier: 21227671

GI number: 21227671

Start: 1868568

End: 1869875

Strand: Direct

Name: fmdB [H]

Synonym: MM_1569

Alternate gene names: 21227671

Gene position: 1868568-1869875 (Clockwise)

Preceding gene: 21227670

Following gene: 21227673

Centisome position: 45.62

GC content: 52.68

Gene sequence:

>1308_bases
GTGAGCATGATTTATAAAAACATAGTCTGTCCGGTCTGCGGGGCAGCCTGCGATGATATCCAGGTCGAGTTCGGGGACGG
AAAGATTGAGGCAAGAAATGCGTGTAAAATGGGGAACGCCAAGTTCCAGGAAGTTGTAAGTTCTCACAGGCTCAGGCAGC
CCCTTATAAAAGTTAACGGAAGGCTGACCGCGGCAGCCTGGGACGAAGCCCTTGAAAGGGCCGCAGATATCCTTGTTTCT
GCAAAGCGCCCTCTCCTTTTTATGGGAAGCGAAACTTCCTGCGAAGCGCATGAAGTCGGGCTCAAGATCGGAGAATATCT
TGGTGCCCTTGTTGACTCAAACGCCACCATTTGCCACGGGCCAACTGCGATGGGAATCCAGGAATCCGGAAAAGTTGGTG
CAACCGAAGGGCAGAAGAAAAACAGAGGCGATCTCATTGTCTACTGGGGAACCAACCCTCTTGAGTCCATGCCGCGTCAG
ATGTCGAGGTACGGAGTTTTCCCAAGAGGTTACTGGACCAAACGAGGGCGTTTTGACAGGACAGTTATCACCGTGGACCC
GAGAAAAACCCCGACCACTGAAGCTTCCGACCTGCACGTGCAGCTCAAGCCCGGCTCGGACTATGAACTGATAAGTGCTC
TCCTCACTTTGCTGCATGGAAAAACTCCTCATCCGTCTGTGGAAGAGATCACAGGAGTACCTATCCCGGTCATGGAAGAG
ATGCTTGACATGATGAAGAACTGCAACTTCGGTGCCATTTCAGTTGGGCTCGGGCTCTCCTCATCCATTGGAAAGCACAG
GAACGCCGAAATTGCCATGAACCTTGTGAAGGAGCTGAACAATTATGCCAAGTTCACTCTCGGAGCTCTTCGAGGTCACT
GCAATGTAGCAGGTTTTAACCAGGTCGCTTCCTACATGTACGGCTACCCCTTCGGGCTGGACTTCATGCGCGGGCACCCG
CGTTACAACCCCGGAGAATATACAACCGTGGACGTGCTGAGGGAAAAAGATGTGGATGCAGCCTTTGTAATGTGCGCCGA
CCTTGTCTGTCACATCCCTGCGGACTGTGCTTCCTATCTTGCTGAAATCCCAATGGTCTGCCTGGACATTGCTCCCTGCC
CGAGCACGGCTGCTTCGGATGTTGTGCTCCCTGGAGTCATTGACGCCATGGAATGTGACGGGACCTTTTACAGGCTCGAC
GATGTGGCAGTGCACTTCGAGCCCTTCACAAGCTCGCCCTTCGAGTTTACGAAGAGCAATGAGGATACCCTGAAGCAGCT
CTTTGAGAAGATAAAGGCAAGGAAGTAA

Upstream 100 bases:

>100_bases
GCTCACCTCTCTATAAGGGAGCTCCCGTATACATTGAGCCGTCAGAAGAAGAGGTCCTCAGCGCCGAAGATGTAGTAATG
AAAATTTATGTTGGAGGGCA

Downstream 100 bases:

>100_bases
ATCTTCACAATTTTCTTCTTGTATAAAAGTATAAATAAGGTTAGAGGAAGAAGGGCATTTTGCCCTTCCAATTCTCTGAT
AATTGTGAGAAATGGTCACT

Product: molybdenum formylmethanofuran dehydrogenase subunit

Products: NA

Alternate protein names: Tungsten-containing formylmethanofuran dehydrogenase II subunit B [H]

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MSMIYKNIVCPVCGAACDDIQVEFGDGKIEARNACKMGNAKFQEVVSSHRLRQPLIKVNGRLTAAAWDEALERAADILVS
AKRPLLFMGSETSCEAHEVGLKIGEYLGALVDSNATICHGPTAMGIQESGKVGATEGQKKNRGDLIVYWGTNPLESMPRQ
MSRYGVFPRGYWTKRGRFDRTVITVDPRKTPTTEASDLHVQLKPGSDYELISALLTLLHGKTPHPSVEEITGVPIPVMEE
MLDMMKNCNFGAISVGLGLSSSIGKHRNAEIAMNLVKELNNYAKFTLGALRGHCNVAGFNQVASYMYGYPFGLDFMRGHP
RYNPGEYTTVDVLREKDVDAAFVMCADLVCHIPADCASYLAEIPMVCLDIAPCPSTAASDVVLPGVIDAMECDGTFYRLD
DVAVHFEPFTSSPFEFTKSNEDTLKQLFEKIKARK

Sequences:

>Translated_435_residues
MSMIYKNIVCPVCGAACDDIQVEFGDGKIEARNACKMGNAKFQEVVSSHRLRQPLIKVNGRLTAAAWDEALERAADILVS
AKRPLLFMGSETSCEAHEVGLKIGEYLGALVDSNATICHGPTAMGIQESGKVGATEGQKKNRGDLIVYWGTNPLESMPRQ
MSRYGVFPRGYWTKRGRFDRTVITVDPRKTPTTEASDLHVQLKPGSDYELISALLTLLHGKTPHPSVEEITGVPIPVMEE
MLDMMKNCNFGAISVGLGLSSSIGKHRNAEIAMNLVKELNNYAKFTLGALRGHCNVAGFNQVASYMYGYPFGLDFMRGHP
RYNPGEYTTVDVLREKDVDAAFVMCADLVCHIPADCASYLAEIPMVCLDIAPCPSTAASDVVLPGVIDAMECDGTFYRLD
DVAVHFEPFTSSPFEFTKSNEDTLKQLFEKIKARK
>Mature_434_residues
SMIYKNIVCPVCGAACDDIQVEFGDGKIEARNACKMGNAKFQEVVSSHRLRQPLIKVNGRLTAAAWDEALERAADILVSA
KRPLLFMGSETSCEAHEVGLKIGEYLGALVDSNATICHGPTAMGIQESGKVGATEGQKKNRGDLIVYWGTNPLESMPRQM
SRYGVFPRGYWTKRGRFDRTVITVDPRKTPTTEASDLHVQLKPGSDYELISALLTLLHGKTPHPSVEEITGVPIPVMEEM
LDMMKNCNFGAISVGLGLSSSIGKHRNAEIAMNLVKELNNYAKFTLGALRGHCNVAGFNQVASYMYGYPFGLDFMRGHPR
YNPGEYTTVDVLREKDVDAAFVMCADLVCHIPADCASYLAEIPMVCLDIAPCPSTAASDVVLPGVIDAMECDGTFYRLDD
VAVHFEPFTSSPFEFTKSNEDTLKQLFEKIKARK

Specific function: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile [H]

COG id: COG1029

COG function: function code C; Formylmethanofuran dehydrogenase subunit B

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fwdB family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=470, Percent_Identity=22.9787234042553, Blast_Score=82, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016457
- InterPro:   IPR006656 [H]

Pfam domain/function: PF00384 Molybdopterin [H]

EC number: =1.2.99.5 [H]

Molecular weight: Translated: 47740; Mature: 47609

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMIYKNIVCPVCGAACDDIQVEFGDGKIEARNACKMGNAKFQEVVSSHRLRQPLIKVNG
CCCHHHHHHHHHHCCCCCCCEEEECCCEEECCHHHCCCCHHHHHHHHHHHHHCCHHHHCC
RLTAAAWDEALERAADILVSAKRPLLFMGSETSCEAHEVGLKIGEYLGALVDSNATICHG
EEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEC
PTAMGIQESGKVGATEGQKKNRGDLIVYWGTNPLESMPRQMSRYGVFPRGYWTKRGRFDR
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
TVITVDPRKTPTTEASDLHVQLKPGSDYELISALLTLLHGKTPHPSVEEITGVPIPVMEE
EEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHH
MLDMMKNCNFGAISVGLGLSSSIGKHRNAEIAMNLVKELNNYAKFTLGALRGHCNVAGFN
HHHHHHCCCCCEEEECCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
QVASYMYGYPFGLDFMRGHPRYNPGEYTTVDVLREKDVDAAFVMCADLVCHIPADCASYL
HHHHHHHCCCCCCHHHCCCCCCCCCCEEHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHH
AEIPMVCLDIAPCPSTAASDVVLPGVIDAMECDGTFYRLDDVAVHFEPFTSSPFEFTKSN
HHCCHHEEECCCCCCCCCCCEECCCHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCCCC
EDTLKQLFEKIKARK
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
SMIYKNIVCPVCGAACDDIQVEFGDGKIEARNACKMGNAKFQEVVSSHRLRQPLIKVNG
CCHHHHHHHHHHCCCCCCCEEEECCCEEECCHHHCCCCHHHHHHHHHHHHHCCHHHHCC
RLTAAAWDEALERAADILVSAKRPLLFMGSETSCEAHEVGLKIGEYLGALVDSNATICHG
EEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEC
PTAMGIQESGKVGATEGQKKNRGDLIVYWGTNPLESMPRQMSRYGVFPRGYWTKRGRFDR
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
TVITVDPRKTPTTEASDLHVQLKPGSDYELISALLTLLHGKTPHPSVEEITGVPIPVMEE
EEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHH
MLDMMKNCNFGAISVGLGLSSSIGKHRNAEIAMNLVKELNNYAKFTLGALRGHCNVAGFN
HHHHHHCCCCCEEEECCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
QVASYMYGYPFGLDFMRGHPRYNPGEYTTVDVLREKDVDAAFVMCADLVCHIPADCASYL
HHHHHHHCCCCCCHHHCCCCCCCCCCEEHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHH
AEIPMVCLDIAPCPSTAASDVVLPGVIDAMECDGTFYRLDDVAVHFEPFTSSPFEFTKSN
HHCCHHEEECCCCCCCCCCCEECCCHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCCCC
EDTLKQLFEKIKARK
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA