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The map label for this gene is mtrA [H]

Identifier: 21227645

GI number: 21227645

Start: 1841467

End: 1842189

Strand: Reverse

Name: mtrA [H]

Synonym: MM_1543

Alternate gene names: 21227645

Gene position: 1842189-1841467 (Counterclockwise)

Preceding gene: 21227646

Following gene: 21227644

Centisome position: 44.97

GC content: 49.65

Gene sequence:

>723_bases
ATGGCAGATAAAAGAGAACCAGCCCCAGGATGGCCTATCCTGAAAGGAGAATACGAAGTAGGCGATGTAAAGAACTCTGT
ACTGGTAATTACCTGCGGCTCACACCTTCCGGGGAAGCCGATTCTTGATGCAGGTGCAGCCTGTACCGGGTCATGTAAGA
CAGAAAACCTTGGTATTGAAAAGGTCGTCGCCCATATCATCTCAAACCCGAACATCAGATACCTGCTTGTAACCGGCTCT
GAAGTTAAGGGGCACATTACCGGACAGTCCATGATGAGCCTCCACGCAAACGGTGTAAAAGAAAACAGGATTGCAGGAGC
ATTGGGTGCAATTCCGTATGTGGAAAACCTTAATGCAGCCGCAGTTGCCCGTTTCCAGGAACAGGTTCAGGTCGTCAATC
TGCTCGATACTGAAGATATGGGGGCTATCACCTCCAAGGTGAGAGAACTGGCCTCAAAAGACCCTGGTGCCTTTGATGCG
GACCCACTGGTTGTAGAAATCAGCGAAGAGGGTGAAGAAGAAGAGGAAGGTGGCGTTGTAAGGCCGGTTTCCGGAGAGAT
CGCTGTTCTCCGTAGCAGGTTGAAAGCAATTGAAGCCCGCATGATGGATATAGGAAACTTGAACAAGTTCCACTCAGGAG
TTCACGCAGGAAAAGTCGAAGGCGCCATGATTGGGTTGACAATAACCATATCCCTGCTTGGGTTATTACTGCTAGGGAGG
TAA

Upstream 100 bases:

>100_bases
TACTCAAACTCCTTCTACGGGATTATTGTAGGTCTTGCTTTCAGCGGACTGCTGGCCCTAATCATATACATAACAAGACT
GATGGGAGGGGTGGTGTAAA

Downstream 100 bases:

>100_bases
TGAAGATGGCAGAAGAACACGAAAAAGGCGTCCCAATGGTGCTTGCCCCTCAGATGGGTGCAATTGATGCGACTGTTGAG
AGCATACGATATAGAGCACA

Product: tetrahydromethanopterin S-methyltransferase subunit A

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MADKREPAPGWPILKGEYEVGDVKNSVLVITCGSHLPGKPILDAGAACTGSCKTENLGIEKVVAHIISNPNIRYLLVTGS
EVKGHITGQSMMSLHANGVKENRIAGALGAIPYVENLNAAAVARFQEQVQVVNLLDTEDMGAITSKVRELASKDPGAFDA
DPLVVEISEEGEEEEEGGVVRPVSGEIAVLRSRLKAIEARMMDIGNLNKFHSGVHAGKVEGAMIGLTITISLLGLLLLGR

Sequences:

>Translated_240_residues
MADKREPAPGWPILKGEYEVGDVKNSVLVITCGSHLPGKPILDAGAACTGSCKTENLGIEKVVAHIISNPNIRYLLVTGS
EVKGHITGQSMMSLHANGVKENRIAGALGAIPYVENLNAAAVARFQEQVQVVNLLDTEDMGAITSKVRELASKDPGAFDA
DPLVVEISEEGEEEEEGGVVRPVSGEIAVLRSRLKAIEARMMDIGNLNKFHSGVHAGKVEGAMIGLTITISLLGLLLLGR
>Mature_239_residues
ADKREPAPGWPILKGEYEVGDVKNSVLVITCGSHLPGKPILDAGAACTGSCKTENLGIEKVVAHIISNPNIRYLLVTGSE
VKGHITGQSMMSLHANGVKENRIAGALGAIPYVENLNAAAVARFQEQVQVVNLLDTEDMGAITSKVRELASKDPGAFDAD
PLVVEISEEGEEEEEGGVVRPVSGEIAVLRSRLKAIEARMMDIGNLNKFHSGVHAGKVEGAMIGLTITISLLGLLLLGR

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step [H]

COG id: COG4063

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit A

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MtrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005778
- InterPro:   IPR013340 [H]

Pfam domain/function: PF04208 MtrA [H]

EC number: =2.1.1.86 [H]

Molecular weight: Translated: 25367; Mature: 25235

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKREPAPGWPILKGEYEVGDVKNSVLVITCGSHLPGKPILDAGAACTGSCKTENLGIE
CCCCCCCCCCCCEEECCEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHH
KVVAHIISNPNIRYLLVTGSEVKGHITGQSMMSLHANGVKENRIAGALGAIPYVENLNAA
HHHHHHHCCCCEEEEEEECCCCEEEECHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCHH
AVARFQEQVQVVNLLDTEDMGAITSKVRELASKDPGAFDADPLVVEISEEGEEEEEGGVV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHCCEE
RPVSGEIAVLRSRLKAIEARMMDIGNLNKFHSGVHAGKVEGAMIGLTITISLLGLLLLGR
ECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADKREPAPGWPILKGEYEVGDVKNSVLVITCGSHLPGKPILDAGAACTGSCKTENLGIE
CCCCCCCCCCCEEECCEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHH
KVVAHIISNPNIRYLLVTGSEVKGHITGQSMMSLHANGVKENRIAGALGAIPYVENLNAA
HHHHHHHCCCCEEEEEEECCCCEEEECHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCHH
AVARFQEQVQVVNLLDTEDMGAITSKVRELASKDPGAFDADPLVVEISEEGEEEEEGGVV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHCCEE
RPVSGEIAVLRSRLKAIEARMMDIGNLNKFHSGVHAGKVEGAMIGLTITISLLGLLLLGR
ECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10338124 [H]