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The map label for this gene is 21227598

Identifier: 21227598

GI number: 21227598

Start: 1783791

End: 1784837

Strand: Reverse

Name: 21227598

Synonym: MM_1496

Alternate gene names: NA

Gene position: 1784837-1783791 (Counterclockwise)

Preceding gene: 21227599

Following gene: 21227595

Centisome position: 43.57

GC content: 47.76

Gene sequence:

>1047_bases
ATGTTATACGCTTTTGAATTATCTGGAGAGCATGAAGAACTGCCAGCCGCCGAAGTCCTTGCCTGCCTCAAAATAGAGGA
GCTTGATTTCAAGCCCTTCATCAGGGTTGACCAGTGCCTTGTAGTGGACATAGCAGGCAGAGAAGAGGAAATTGAAAGAA
CTCTGACATGCACTATAACCGAAAGGCTGGCAATGACCCATCATATACTGAAAGTTGTAGGAATTGCCGAAAACAGCCCT
GAAGCCATTCTTGAGCTTGCGGAAGCTTTTGAGCCCGAAGGATACATAAAAGAAGGAGAAAGCTTTGTTGTCAGGGCAAA
GAGAATTAAACACCACGTTGATTTTCCGTGCGAGTACCTGGAACAGAAGATTGGAGGCTGCATCTACAGGAAAGGTTTCA
GGGCAAACCTGAAAAACGCTGATGTGGAATTCCGGCTGATCCTGAGCGAAAAAGCAGTACTTGGAACCCTGATTTCCTCT
GTAGACAGGAGCGCATATGAAGCCAGGACTCCCCAGAACAAGCCTTTTTTCCACCCCGGTGTGCTTATGCCAAGGGTTGC
ACGTGCACTTACGAATTTATCCGGGATAAAGCCCGGAGAGCTCTTTCTTGACCCCTTCTGCGGCACTGCTGGAATACTTG
TAGAAGCCGGGCTTGTGGGCGCAAAGGTTGTGGGAATTGATGCCCAGGAAAAGCTTGTCCTCGGGGCTTATATGAACCTG
GAAGCCTATGAACTGGACTATTTTTTGATGGAAGGGGATGCCTGTAGAATTCCCCTGAAGGATTACACAATAGATGCAGT
TGTTACTGATCCTCCTTACGGCAGGTCGGCAGCAATTCTTGCCAGTTCCCTGGAAGAGTTATATTCGGGTGCTCTTTCGG
AAATCCAGCGTGTCCTGAAACCCGGAGGAATTGCAGTTGTCGTCTCTGATAAGGCATCAGTTGAATACGGGGAAAAAGCC
GGGCTTAAGGTCCTTGAAATATATGTCCAGAGGGTGCACAGGAGCCTTACACGGATAATAACAATTTTTCAGAAGGATGA
GGATTGA

Upstream 100 bases:

>100_bases
TGAATTACCATTACTGTGAACTGACATCGTCTGTTTAGAACTGACTGAAGATTATTTCAAACTATATTAATCAACATTAA
TCAACACGTTTCGGATTATC

Downstream 100 bases:

>100_bases
AGTTGTCTGGAGGAATGAAAGAATGGAAAGAAAAAAAGATAATTAAAAAGTGAGAAACTGAGCCAGAGACTGAGCCAGAA
CCTGAATAAAGATAAAAAAT

Product: putative methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MLYAFELSGEHEELPAAEVLACLKIEELDFKPFIRVDQCLVVDIAGREEEIERTLTCTITERLAMTHHILKVVGIAENSP
EAILELAEAFEPEGYIKEGESFVVRAKRIKHHVDFPCEYLEQKIGGCIYRKGFRANLKNADVEFRLILSEKAVLGTLISS
VDRSAYEARTPQNKPFFHPGVLMPRVARALTNLSGIKPGELFLDPFCGTAGILVEAGLVGAKVVGIDAQEKLVLGAYMNL
EAYELDYFLMEGDACRIPLKDYTIDAVVTDPPYGRSAAILASSLEELYSGALSEIQRVLKPGGIAVVVSDKASVEYGEKA
GLKVLEIYVQRVHRSLTRIITIFQKDED

Sequences:

>Translated_348_residues
MLYAFELSGEHEELPAAEVLACLKIEELDFKPFIRVDQCLVVDIAGREEEIERTLTCTITERLAMTHHILKVVGIAENSP
EAILELAEAFEPEGYIKEGESFVVRAKRIKHHVDFPCEYLEQKIGGCIYRKGFRANLKNADVEFRLILSEKAVLGTLISS
VDRSAYEARTPQNKPFFHPGVLMPRVARALTNLSGIKPGELFLDPFCGTAGILVEAGLVGAKVVGIDAQEKLVLGAYMNL
EAYELDYFLMEGDACRIPLKDYTIDAVVTDPPYGRSAAILASSLEELYSGALSEIQRVLKPGGIAVVVSDKASVEYGEKA
GLKVLEIYVQRVHRSLTRIITIFQKDED
>Mature_348_residues
MLYAFELSGEHEELPAAEVLACLKIEELDFKPFIRVDQCLVVDIAGREEEIERTLTCTITERLAMTHHILKVVGIAENSP
EAILELAEAFEPEGYIKEGESFVVRAKRIKHHVDFPCEYLEQKIGGCIYRKGFRANLKNADVEFRLILSEKAVLGTLISS
VDRSAYEARTPQNKPFFHPGVLMPRVARALTNLSGIKPGELFLDPFCGTAGILVEAGLVGAKVVGIDAQEKLVLGAYMNL
EAYELDYFLMEGDACRIPLKDYTIDAVVTDPPYGRSAAILASSLEELYSGALSEIQRVLKPGGIAVVVSDKASVEYGEKA
GLKVLEIYVQRVHRSLTRIITIFQKDED

Specific function: Unknown

COG id: COG1041

COG function: function code L; Predicted DNA modification methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 THUMP domain [H]

Homologues:

Organism=Homo sapiens, GI254553431, Length=200, Percent_Identity=27.5, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32566195, Length=193, Percent_Identity=26.4248704663212, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005885
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR000241
- InterPro:   IPR004114 [H]

Pfam domain/function: PF02926 THUMP; PF01170 UPF0020 [H]

EC number: NA

Molecular weight: Translated: 38565; Mature: 38565

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS51165 THUMP ; PS00092 N6_MTASE ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYAFELSGEHEELPAAEVLACLKIEELDFKPFIRVDQCLVVDIAGREEEIERTLTCTIT
CEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEECCEEEEEECCCHHHHHHHEEEHHH
ERLAMTHHILKVVGIAENSPEAILELAEAFEPEGYIKEGESFVVRAKRIKHHVDFPCEYL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHH
EQKIGGCIYRKGFRANLKNADVEFRLILSEKAVLGTLISSVDRSAYEARTPQNKPFFHPG
HHHHCCEEECCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
VLMPRVARALTNLSGIKPGELFLDPFCGTAGILVEAGLVGAKVVGIDAQEKLVLGAYMNL
CHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHCCCCCEEEEECCCHHCEEEEEEECC
EAYELDYFLMEGDACRIPLKDYTIDAVVTDPPYGRSAAILASSLEELYSGALSEIQRVLK
EEEEEEEEEEECCEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
PGGIAVVVSDKASVEYGEKAGLKVLEIYVQRVHRSLTRIITIFQKDED
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLYAFELSGEHEELPAAEVLACLKIEELDFKPFIRVDQCLVVDIAGREEEIERTLTCTIT
CEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEECCEEEEEECCCHHHHHHHEEEHHH
ERLAMTHHILKVVGIAENSPEAILELAEAFEPEGYIKEGESFVVRAKRIKHHVDFPCEYL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHH
EQKIGGCIYRKGFRANLKNADVEFRLILSEKAVLGTLISSVDRSAYEARTPQNKPFFHPG
HHHHCCEEECCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
VLMPRVARALTNLSGIKPGELFLDPFCGTAGILVEAGLVGAKVVGIDAQEKLVLGAYMNL
CHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHCCCCCEEEEECCCHHCEEEEEEECC
EAYELDYFLMEGDACRIPLKDYTIDAVVTDPPYGRSAAILASSLEELYSGALSEIQRVLK
EEEEEEEEEEECCEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
PGGIAVVVSDKASVEYGEKAGLKVLEIYVQRVHRSLTRIITIFQKDED
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]