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The map label for this gene is glyS [H]

Identifier: 21227490

GI number: 21227490

Start: 1669582

End: 1671540

Strand: Reverse

Name: glyS [H]

Synonym: MM_1388

Alternate gene names: 21227490

Gene position: 1671540-1669582 (Counterclockwise)

Preceding gene: 21227491

Following gene: 21227489

Centisome position: 40.81

GC content: 48.65

Gene sequence:

>1959_bases
ATGATTCCCTTTATCCATCTATTATTTCTAACAAATCAAAAATTCACGATTACCCTGTATCCCCCAATCAATATTAAGAG
GACTTATAAAATGGACAAATACGAAAAAGTATTCGAGCTGGCAAAACGCCGCGGCTTTTTATGGAATTCATTTGAGCTGT
ATGGCGGAAGCCGCGGGTTTTATGATTACGGGCCTTTAGGGAGCACGCTGAAAAGGCGCATAGAGCAGATCTGGAGAGAG
TTTTACGTAATTCAGGAAGGGCATATGGAAATCGAGTGCCCGACCATAGGTATCGAGGATGTTTTTGTCGCATCAGGGCA
CGTTGGAGGCTTTTCTGACCCCCTGTGCGAATGCAAGAAATGTGGAGAGGCTTTCCGGGCAGACCACCTGGTGGAAAACG
TCATGGATGCGGCAGGGACCCTGAGCGCAGAACAGCTCACAGAAGTCATAAAGGAAAAGGGGATCACCTGTCCCGAGTGT
GGCGGAGAGCTCAACGACGCTTATGAATTTAACCTGATGTTCAAGACCACAATCGGGCCCGGAACCGGAAGGCAGGGTTA
CCTCAGGCCGGAAACAGCGCAGGGGATGTTTGTTGACTTCCAGAGGCTTTCCCGATTCTATAGAGACAAGCTGCCTTTTG
GGGCTGTGCAGATAGGCAAATCTTACAGGAACGAAATTGCACCAAGGCAGGGTGTTATAAGGCTCAGGGAATTCACTCAG
GCTGAATGTGAACTCTTTGTTGACCCGAGGAACAAGAAGCACTCCAATTTCGAGCGCTTCGCGGAAAAAGAACTTGTTCT
TTACTCACAGGCAGCCCAGCAAACAGGTGAACCGATCAGGATGACAGTTCGCGAAGCTGTAGAAACCGGCGTTATCGCCC
ACGAAGTCCTAGGTTACAACATCGCTCTTACAAACGAGTTTCTGACAAAAGTAGGGATCGAACCTGCAAAGCTCAGGTTC
AGGCAGCACCTGAAAGACGAGATGGCACACTACGCAATCGACTGCTGGGATGCCGAAATCGAAACAGACCGCTTCGGCTG
GGTTGAAATTGTGGGCATTGCAGACAGGACTGATTATGACCTTAAAGCCCACGCAAGGGTCAGCAAGACAGATCTTTACG
TTTACGTAGAGTATGACGAGCCCAAAATGGTGACCCGTTTTGTTGTGAAACCGAATATGGGCAAACTCGGCCCCCTCTTC
AAGGGCAAAGCAAAAGCCGTTGCAGACGCCTTAAAACAGCTTTCGGAAGAAGAGCTCTCAAAGGACCAGATCACAGTTAC
AGTAGACGGAGAAGAACTGTCTGTAAGTTCGGATGTAGTGGATTTTGCCGAAGAGACCGTAAAGGTCAGCGGAGAAAACG
TCATTCCTCACGTCATTGAGCCTTCTTATGGTATAGACAGGATCTTCTACGGTACCATGGAACACGCCTTTGACGAAGAA
AATGTTGCTAAGAAAGCAGCAGAATCCGGTCTCAAAGGTGCAGAAGAAGCAGAAGGTGCAGAGAAAACAGAAGGTGCAGA
GAAAGCAGAAAAGGCAGAAAAAGGACCGGAAGCAACAAAGGATGAAACTGAGGGAGAAGGTGAAGAAGAAACCCGCCTTG
TGATGCACTTCTCAAGTTCAGTAGCCCCTGTTCAGGTAGCGGTCCTCCCGCTTCTTACCAGGAAAGAGCTTGCAGACCCT
GCAAAAGAGATCGTTGCAAAACTCAGGGAAAAGAACCTGCTCGTCAATTACGACGACTCCGGAACCATCGGGCGCCGCTA
CAGGAGAAATGATGAAATCGGGACTCCATACTCGGTTACTGTTGATTATGATACCCTTCAGGACGGGACCGTCACAATCA
GGGACAGAGACTCCATGCGCCAGATAAGGGCTCCAATCAGTGGAATCGAAAACGTGCTCTACGAACTGATCTACAGGGGC
AGAAATTTCGAATCTGCAGGTAAACCCTTTAATTTCTAA

Upstream 100 bases:

>100_bases
TCACTATGGAAAACTTGATCGATGAAGCTAAACCTTTACCATCAAATATCGTTTTCTATCTCCTCAACCCCTCGTCTCAG
AGCAGTGCAAATTTAATATA

Downstream 100 bases:

>100_bases
ATTAGAATTAATAAAAGAATGAATTAAGGGAATAAGTATAACCTGTAAATTCCTGAGCTGCGGGCTGAAAAGCCTACAGC
AAAATATTTAATTTTTTATT

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 652; Mature: 652

Protein sequence:

>652_residues
MIPFIHLLFLTNQKFTITLYPPINIKRTYKMDKYEKVFELAKRRGFLWNSFELYGGSRGFYDYGPLGSTLKRRIEQIWRE
FYVIQEGHMEIECPTIGIEDVFVASGHVGGFSDPLCECKKCGEAFRADHLVENVMDAAGTLSAEQLTEVIKEKGITCPEC
GGELNDAYEFNLMFKTTIGPGTGRQGYLRPETAQGMFVDFQRLSRFYRDKLPFGAVQIGKSYRNEIAPRQGVIRLREFTQ
AECELFVDPRNKKHSNFERFAEKELVLYSQAAQQTGEPIRMTVREAVETGVIAHEVLGYNIALTNEFLTKVGIEPAKLRF
RQHLKDEMAHYAIDCWDAEIETDRFGWVEIVGIADRTDYDLKAHARVSKTDLYVYVEYDEPKMVTRFVVKPNMGKLGPLF
KGKAKAVADALKQLSEEELSKDQITVTVDGEELSVSSDVVDFAEETVKVSGENVIPHVIEPSYGIDRIFYGTMEHAFDEE
NVAKKAAESGLKGAEEAEGAEKTEGAEKAEKAEKGPEATKDETEGEGEEETRLVMHFSSSVAPVQVAVLPLLTRKELADP
AKEIVAKLREKNLLVNYDDSGTIGRRYRRNDEIGTPYSVTVDYDTLQDGTVTIRDRDSMRQIRAPISGIENVLYELIYRG
RNFESAGKPFNF

Sequences:

>Translated_652_residues
MIPFIHLLFLTNQKFTITLYPPINIKRTYKMDKYEKVFELAKRRGFLWNSFELYGGSRGFYDYGPLGSTLKRRIEQIWRE
FYVIQEGHMEIECPTIGIEDVFVASGHVGGFSDPLCECKKCGEAFRADHLVENVMDAAGTLSAEQLTEVIKEKGITCPEC
GGELNDAYEFNLMFKTTIGPGTGRQGYLRPETAQGMFVDFQRLSRFYRDKLPFGAVQIGKSYRNEIAPRQGVIRLREFTQ
AECELFVDPRNKKHSNFERFAEKELVLYSQAAQQTGEPIRMTVREAVETGVIAHEVLGYNIALTNEFLTKVGIEPAKLRF
RQHLKDEMAHYAIDCWDAEIETDRFGWVEIVGIADRTDYDLKAHARVSKTDLYVYVEYDEPKMVTRFVVKPNMGKLGPLF
KGKAKAVADALKQLSEEELSKDQITVTVDGEELSVSSDVVDFAEETVKVSGENVIPHVIEPSYGIDRIFYGTMEHAFDEE
NVAKKAAESGLKGAEEAEGAEKTEGAEKAEKAEKGPEATKDETEGEGEEETRLVMHFSSSVAPVQVAVLPLLTRKELADP
AKEIVAKLREKNLLVNYDDSGTIGRRYRRNDEIGTPYSVTVDYDTLQDGTVTIRDRDSMRQIRAPISGIENVLYELIYRG
RNFESAGKPFNF
>Mature_652_residues
MIPFIHLLFLTNQKFTITLYPPINIKRTYKMDKYEKVFELAKRRGFLWNSFELYGGSRGFYDYGPLGSTLKRRIEQIWRE
FYVIQEGHMEIECPTIGIEDVFVASGHVGGFSDPLCECKKCGEAFRADHLVENVMDAAGTLSAEQLTEVIKEKGITCPEC
GGELNDAYEFNLMFKTTIGPGTGRQGYLRPETAQGMFVDFQRLSRFYRDKLPFGAVQIGKSYRNEIAPRQGVIRLREFTQ
AECELFVDPRNKKHSNFERFAEKELVLYSQAAQQTGEPIRMTVREAVETGVIAHEVLGYNIALTNEFLTKVGIEPAKLRF
RQHLKDEMAHYAIDCWDAEIETDRFGWVEIVGIADRTDYDLKAHARVSKTDLYVYVEYDEPKMVTRFVVKPNMGKLGPLF
KGKAKAVADALKQLSEEELSKDQITVTVDGEELSVSSDVVDFAEETVKVSGENVIPHVIEPSYGIDRIFYGTMEHAFDEE
NVAKKAAESGLKGAEEAEGAEKTEGAEKAEKAEKGPEATKDETEGEGEEETRLVMHFSSSVAPVQVAVLPLLTRKELADP
AKEIVAKLREKNLLVNYDDSGTIGRRYRRNDEIGTPYSVTVDYDTLQDGTVTIRDRDSMRQIRAPISGIENVLYELIYRG
RNFESAGKPFNF

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=634, Percent_Identity=40.2208201892744, Blast_Score=444, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI32564541, Length=637, Percent_Identity=39.0894819466248, Blast_Score=435, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17554996, Length=637, Percent_Identity=39.0894819466248, Blast_Score=434, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6325338, Length=640, Percent_Identity=35.625, Blast_Score=418, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6319597, Length=687, Percent_Identity=35.5167394468704, Blast_Score=411, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24664462, Length=621, Percent_Identity=39.1304347826087, Blast_Score=431, Evalue=1e-121,
Organism=Drosophila melanogaster, GI21357965, Length=621, Percent_Identity=39.1304347826087, Blast_Score=430, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022960
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 73784; Mature: 73784

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPFIHLLFLTNQKFTITLYPPINIKRTYKMDKYEKVFELAKRRGFLWNSFELYGGSRGF
CCCEEEEEEEECCEEEEEEECCCCCEECCCCHHHHHHHHHHHHCCCEECCEEEECCCCCC
YDYGPLGSTLKRRIEQIWREFYVIQEGHMEIECPTIGIEDVFVASGHVGGFSDPLCECKK
CCCCCCCHHHHHHHHHHHHHHHEEECCCEEEECCCCCCCCEEEECCCCCCCCCHHHHHHH
CGEAFRADHLVENVMDAAGTLSAEQLTEVIKEKGITCPECGGELNDAYEFNLMFKTTIGP
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECC
GTGRQGYLRPETAQGMFVDFQRLSRFYRDKLPFGAVQIGKSYRNEIAPRQGVIRLREFTQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCC
AECELFVDPRNKKHSNFERFAEKELVLYSQAAQQTGEPIRMTVREAVETGVIAHEVLGYN
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCE
IALTNEFLTKVGIEPAKLRFRQHLKDEMAHYAIDCWDAEIETDRFGWVEIVGIADRTDYD
EEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEEEECCCCCCC
LKAHARVSKTDLYVYVEYDEPKMVTRFVVKPNMGKLGPLFKGKAKAVADALKQLSEEELS
CEECCEEEEEEEEEEEEECCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
KDQITVTVDGEELSVSSDVVDFAEETVKVSGENVIPHVIEPSYGIDRIFYGTMEHAFDEE
CCEEEEEECCCEEECHHHHHHHHHHHHEECCCCCCCEECCCCCCCHHHHHHHHHHHCCHH
NVAKKAAESGLKGAEEAEGAEKTEGAEKAEKAEKGPEATKDETEGEGEEETRLVMHFSSS
HHHHHHHHHCCCCCHHHCCCHHHCCHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEECCC
VAPVQVAVLPLLTRKELADPAKEIVAKLREKNLLVNYDDSGTIGRRYRRNDEIGTPYSVT
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCCCCHHHHHCCCCCCCCCEEEE
VDYDTLQDGTVTIRDRDSMRQIRAPISGIENVLYELIYRGRNFESAGKPFNF
EECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MIPFIHLLFLTNQKFTITLYPPINIKRTYKMDKYEKVFELAKRRGFLWNSFELYGGSRGF
CCCEEEEEEEECCEEEEEEECCCCCEECCCCHHHHHHHHHHHHCCCEECCEEEECCCCCC
YDYGPLGSTLKRRIEQIWREFYVIQEGHMEIECPTIGIEDVFVASGHVGGFSDPLCECKK
CCCCCCCHHHHHHHHHHHHHHHEEECCCEEEECCCCCCCCEEEECCCCCCCCCHHHHHHH
CGEAFRADHLVENVMDAAGTLSAEQLTEVIKEKGITCPECGGELNDAYEFNLMFKTTIGP
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECC
GTGRQGYLRPETAQGMFVDFQRLSRFYRDKLPFGAVQIGKSYRNEIAPRQGVIRLREFTQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCC
AECELFVDPRNKKHSNFERFAEKELVLYSQAAQQTGEPIRMTVREAVETGVIAHEVLGYN
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCE
IALTNEFLTKVGIEPAKLRFRQHLKDEMAHYAIDCWDAEIETDRFGWVEIVGIADRTDYD
EEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEEEECCCCCCC
LKAHARVSKTDLYVYVEYDEPKMVTRFVVKPNMGKLGPLFKGKAKAVADALKQLSEEELS
CEECCEEEEEEEEEEEEECCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
KDQITVTVDGEELSVSSDVVDFAEETVKVSGENVIPHVIEPSYGIDRIFYGTMEHAFDEE
CCEEEEEECCCEEECHHHHHHHHHHHHEECCCCCCCEECCCCCCCHHHHHHHHHHHCCHH
NVAKKAAESGLKGAEEAEGAEKTEGAEKAEKAEKGPEATKDETEGEGEEETRLVMHFSSS
HHHHHHHHHCCCCCHHHCCCHHHCCHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEECCC
VAPVQVAVLPLLTRKELADPAKEIVAKLREKNLLVNYDDSGTIGRRYRRNDEIGTPYSVT
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCCCCHHHHHCCCCCCCCCEEEE
VDYDTLQDGTVTIRDRDSMRQIRAPISGIENVLYELIYRGRNFESAGKPFNF
EECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA