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The map label for this gene is znuB [C]

Identifier: 21227437

GI number: 21227437

Start: 1592607

End: 1593431

Strand: Direct

Name: znuB [C]

Synonym: MM_1335

Alternate gene names: 21227437

Gene position: 1592607-1593431 (Clockwise)

Preceding gene: 21227436

Following gene: 21227438

Centisome position: 38.88

GC content: 42.42

Gene sequence:

>825_bases
ATGTTTGATCTTCTTCAATATACTTTCATCCAGAACGCCCTTATAGCCGCAGTCCTTGCAAGTGTTGCCTGCGGAATAAT
AGGCTCATATGTTGTTGTTAAAAAGATTGTCTTTATCAGTGGGGGAATTGCCCATGCTTCATTCGGAGGAGTGGGGCTTG
GATATTACCTTGGTATCAATCCAATGTACGGAGTCCTCCCTTTCAGCCTTCTGTCAGCTCTCGTTATGGGTACCGTAAGC
AAGAAATCAAAAATCCCTGAGGACAGTGCAATAGGTATACTCTGGTCTCTTGGAATGGCTCTGGGAGTTATTTTTGTCTA
TCTCACTCCAGGATATGCTCCGGATCTGATGACCTACCTTTTCGGAAACATCCTTACAGTCCCCCGTCTGGACCTGTATC
TTATGCTGGCTCTTGATATCATCATAGTAGGTGCAGTCTATCTATTCTATAAGGAGTTCCTTGCTTTATGTTTTGACGAG
GAGTTTACAACTGTGCAGGGCGTTCCCACTGACAAACTTTACCTTTTCCTGCTCTGTATTATTGCCCTTACAATTGTGGT
TCTTATCAAAGTTGTGGGAATCATCCTTGTAATAGCTCTTCTAACAATTCCTGCCACTATTAGCCGCAAGTTTACTCATA
ACCTGAAGAAAATGATGCTTATATCTACCGCTTTTGGGGCTGTTATCAGTGTCGCAGGAATAGGTCTATCCTATATTCTG
GACGTTCCGTCAGGAGCCACTATTATTCTGGTGTTAAGTTTTGTTTATGGGTTTGTAGCTGTAGGGACGGAAATGTTCAA
AGACAAAAATGCTTTTAAAAGCTGA

Upstream 100 bases:

>100_bases
TGCTCACGGAGTGCCCCACAGAGTGCTTGAGAGGCATAAAGAGAGTCCCTGAAGATCAAGGATCAGGTTCGAAAAACAGT
CTCTAAAGGAGAAATGAAAA

Downstream 100 bases:

>100_bases
AAAATTCTAAAATTAATTTTTTTAGGGTTCTCAATCAGGACGGGTTGGAATATAAAAGCTCAAATATTTATGCCAGCATA
TATCAGTATTAATATATTTG

Product: Zinc ABC transporter permease

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MFDLLQYTFIQNALIAAVLASVACGIIGSYVVVKKIVFISGGIAHASFGGVGLGYYLGINPMYGVLPFSLLSALVMGTVS
KKSKIPEDSAIGILWSLGMALGVIFVYLTPGYAPDLMTYLFGNILTVPRLDLYLMLALDIIIVGAVYLFYKEFLALCFDE
EFTTVQGVPTDKLYLFLLCIIALTIVVLIKVVGIILVIALLTIPATISRKFTHNLKKMMLISTAFGAVISVAGIGLSYIL
DVPSGATIILVLSFVYGFVAVGTEMFKDKNAFKS

Sequences:

>Translated_274_residues
MFDLLQYTFIQNALIAAVLASVACGIIGSYVVVKKIVFISGGIAHASFGGVGLGYYLGINPMYGVLPFSLLSALVMGTVS
KKSKIPEDSAIGILWSLGMALGVIFVYLTPGYAPDLMTYLFGNILTVPRLDLYLMLALDIIIVGAVYLFYKEFLALCFDE
EFTTVQGVPTDKLYLFLLCIIALTIVVLIKVVGIILVIALLTIPATISRKFTHNLKKMMLISTAFGAVISVAGIGLSYIL
DVPSGATIILVLSFVYGFVAVGTEMFKDKNAFKS
>Mature_274_residues
MFDLLQYTFIQNALIAAVLASVACGIIGSYVVVKKIVFISGGIAHASFGGVGLGYYLGINPMYGVLPFSLLSALVMGTVS
KKSKIPEDSAIGILWSLGMALGVIFVYLTPGYAPDLMTYLFGNILTVPRLDLYLMLALDIIIVGAVYLFYKEFLALCFDE
EFTTVQGVPTDKLYLFLLCIIALTIVVLIKVVGIILVIALLTIPATISRKFTHNLKKMMLISTAFGAVISVAGIGLSYIL
DVPSGATIILVLSFVYGFVAVGTEMFKDKNAFKS

Specific function: Involved In The High-Affinity Zinc Uptake Transport System. [C]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=243, Percent_Identity=30.8641975308642, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 29487; Mature: 29487

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDLLQYTFIQNALIAAVLASVACGIIGSYVVVKKIVFISGGIAHASFGGVGLGYYLGIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHCCC
PMYGVLPFSLLSALVMGTVSKKSKIPEDSAIGILWSLGMALGVIFVYLTPGYAPDLMTYL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
FGNILTVPRLDLYLMLALDIIIVGAVYLFYKEFLALCFDEEFTTVQGVPTDKLYLFLLCI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHH
IALTIVVLIKVVGIILVIALLTIPATISRKFTHNLKKMMLISTAFGAVISVAGIGLSYIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
DVPSGATIILVLSFVYGFVAVGTEMFKDKNAFKS
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFDLLQYTFIQNALIAAVLASVACGIIGSYVVVKKIVFISGGIAHASFGGVGLGYYLGIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHCCC
PMYGVLPFSLLSALVMGTVSKKSKIPEDSAIGILWSLGMALGVIFVYLTPGYAPDLMTYL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
FGNILTVPRLDLYLMLALDIIIVGAVYLFYKEFLALCFDEEFTTVQGVPTDKLYLFLLCI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHH
IALTIVVLIKVVGIILVIALLTIPATISRKFTHNLKKMMLISTAFGAVISVAGIGLSYIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
DVPSGATIILVLSFVYGFVAVGTEMFKDKNAFKS
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]