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The map label for this gene is cdc6 [H]

Identifier: 21227416

GI number: 21227416

Start: 1563412

End: 1564656

Strand: Reverse

Name: cdc6 [H]

Synonym: MM_1314

Alternate gene names: 21227416

Gene position: 1564656-1563412 (Counterclockwise)

Preceding gene: 21227422

Following gene: 161485677

Centisome position: 38.2

GC content: 43.69

Gene sequence:

>1245_bases
ATGATAAAGGCTCAATCATTAGACGGCTTGTTCGAAAAATTACTTGACGGAAAGTCAATTTTCAAAAATAAAGAAGTCCT
TCGTCCTTCTTATACTCCGGATCTGTTATTACACAGAAACGACCAGATAAACAGCCTTGCAACCATCCTGGTATCCGCGC
TCAGGGGAGAAACTCCTTCAAATGTCCTGATTTACGGAAAAACAGGGACAGGAAAAACCGCAGTGACCAGATATGTAGGA
AAAGAGCTCGAAAGAGTAAGTGAAGACAAATCAATTTTCTGTTCTGTTGTTTATATTAATTGTGAAGTGATCGACACCCA
GTATCGGCTTCTTGCAAACCTTGCCAGGCATTTTGAAGAAGAGGTCCCTATGACCGGGTGGCCCACGGATCAGGTCTTTA
TGAAATTTAAAGAAGCAATCGATTCAAGGGAACAGGTTATTATTATCATTCTTGATGAAATTGACAAGCTGATAAAAAAA
GGCGACGATGTTCTTTACAATCTTTCAAGGATTAATACCGATTTAAGGAAAGCCAAGGTTAGCATGATTGGAGTTTCCAA
TGACCTCAAATTCACGGAATTTCTCGACCCGAGAGTTAAAAGTTCTCTGGGCGAAGAAGAACTTATTTTTCCGCCTTATG
ATGCTGAACAGATCAGTGATATCCTGAAACAGAGGGCTAAAATGGCTTACAATGACGGAGTCCTGGGCGAAATGGTAATT
CCGCTCTGTGCAGCCTTTGCAGCTCAGGAACACGGTGATGCCCGCCGTGCGCTTGACCTTCTGCGAGTTTCAGGAGAAAT
TGCTGAGAGAGAAAACCAGCCCCAGGTTCTTGAAGAACATGTAAGGCGCGCGCAGGAGAAAATTGAAATCGACCGTGTCG
TGGAAGTTGTGCGGACCCTTCCCACCCAGTCCAAGCTTGTGCTCTACAGCATCATCCTGCTCAGAAACAGGGGAAGAGAA
GGCAAAAATGTCACAACCGGCGAAATGTATAATGTTTACCGCCAGCTCTGTCATCACATTGATGTGGATATTCTTACCCA
GCGCAGGGTTACTGACCTGATGTCAGAACTTGACATGCTCGGGATAGTCAATGCTGTGGTGGTAAGCAAAGGACGTTACG
GAAGGACAAAAGAAATCTCTTTGAGTGTTCCCGTAGAAAACACCCGCAAAGTACTTCTTGAAGACTACAGACTTAAACCC
CTTGTAGATTTCAAGGCTTCAGTGTTCAATAAAATGTTCTCATAA

Upstream 100 bases:

>100_bases
TCTGCATATTATGTCAGCTATATGTTAGGCTATCCTAACCCGTTAAATCCAGATATTATAACAAATCCATGATATTATAA
CTTTTATTAAGAGGGTCATT

Downstream 100 bases:

>100_bases
CATTATGTTCTAGCAACATAATATTCTTGTAAACACTTTTAAAATAAACATTTTTTAAATAATTTTTAATACCGAGTAAA
TCCTGGAAAGTGCGGATTAG

Product: cell division control protein 6

Products: NA

Alternate protein names: CDC6 homolog 1 [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MIKAQSLDGLFEKLLDGKSIFKNKEVLRPSYTPDLLLHRNDQINSLATILVSALRGETPSNVLIYGKTGTGKTAVTRYVG
KELERVSEDKSIFCSVVYINCEVIDTQYRLLANLARHFEEEVPMTGWPTDQVFMKFKEAIDSREQVIIIILDEIDKLIKK
GDDVLYNLSRINTDLRKAKVSMIGVSNDLKFTEFLDPRVKSSLGEEELIFPPYDAEQISDILKQRAKMAYNDGVLGEMVI
PLCAAFAAQEHGDARRALDLLRVSGEIAERENQPQVLEEHVRRAQEKIEIDRVVEVVRTLPTQSKLVLYSIILLRNRGRE
GKNVTTGEMYNVYRQLCHHIDVDILTQRRVTDLMSELDMLGIVNAVVVSKGRYGRTKEISLSVPVENTRKVLLEDYRLKP
LVDFKASVFNKMFS

Sequences:

>Translated_414_residues
MIKAQSLDGLFEKLLDGKSIFKNKEVLRPSYTPDLLLHRNDQINSLATILVSALRGETPSNVLIYGKTGTGKTAVTRYVG
KELERVSEDKSIFCSVVYINCEVIDTQYRLLANLARHFEEEVPMTGWPTDQVFMKFKEAIDSREQVIIIILDEIDKLIKK
GDDVLYNLSRINTDLRKAKVSMIGVSNDLKFTEFLDPRVKSSLGEEELIFPPYDAEQISDILKQRAKMAYNDGVLGEMVI
PLCAAFAAQEHGDARRALDLLRVSGEIAERENQPQVLEEHVRRAQEKIEIDRVVEVVRTLPTQSKLVLYSIILLRNRGRE
GKNVTTGEMYNVYRQLCHHIDVDILTQRRVTDLMSELDMLGIVNAVVVSKGRYGRTKEISLSVPVENTRKVLLEDYRLKP
LVDFKASVFNKMFS
>Mature_414_residues
MIKAQSLDGLFEKLLDGKSIFKNKEVLRPSYTPDLLLHRNDQINSLATILVSALRGETPSNVLIYGKTGTGKTAVTRYVG
KELERVSEDKSIFCSVVYINCEVIDTQYRLLANLARHFEEEVPMTGWPTDQVFMKFKEAIDSREQVIIIILDEIDKLIKK
GDDVLYNLSRINTDLRKAKVSMIGVSNDLKFTEFLDPRVKSSLGEEELIFPPYDAEQISDILKQRAKMAYNDGVLGEMVI
PLCAAFAAQEHGDARRALDLLRVSGEIAERENQPQVLEEHVRRAQEKIEIDRVVEVVRTLPTQSKLVLYSIILLRNRGRE
GKNVTTGEMYNVYRQLCHHIDVDILTQRRVTDLMSELDMLGIVNAVVVSKGRYGRTKEISLSVPVENTRKVLLEDYRLKP
LVDFKASVFNKMFS

Specific function: Might be involved in the initiation of DNA replication [H]

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family [H]

Homologues:

Organism=Homo sapiens, GI4502703, Length=374, Percent_Identity=26.2032085561497, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17555708, Length=387, Percent_Identity=26.3565891472868, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17506005, Length=227, Percent_Identity=27.3127753303965, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323575, Length=307, Percent_Identity=24.1042345276873, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21355681, Length=358, Percent_Identity=24.5810055865922, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI17137456, Length=291, Percent_Identity=25.4295532646048, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00004 AAA; PF09079 Cdc6_C [H]

EC number: NA

Molecular weight: Translated: 47152; Mature: 47152

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKAQSLDGLFEKLLDGKSIFKNKEVLRPSYTPDLLLHRNDQINSLATILVSALRGETPS
CCCCCHHHHHHHHHHCCHHHHCCCHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCC
NVLIYGKTGTGKTAVTRYVGKELERVSEDKSIFCSVVYINCEVIDTQYRLLANLARHFEE
CEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHH
EVPMTGWPTDQVFMKFKEAIDSREQVIIIILDEIDKLIKKGDDVLYNLSRINTDLRKAKV
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCHHEEHHHHHHHHHHHHHH
SMIGVSNDLKFTEFLDPRVKSSLGEEELIFPPYDAEQISDILKQRAKMAYNDGVLGEMVI
HEEECCCCCCHHHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
PLCAAFAAQEHGDARRALDLLRVSGEIAERENQPQVLEEHVRRAQEKIEIDRVVEVVRTL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PTQSKLVLYSIILLRNRGREGKNVTTGEMYNVYRQLCHHIDVDILTQRRVTDLMSELDML
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GIVNAVVVSKGRYGRTKEISLSVPVENTRKVLLEDYRLKPLVDFKASVFNKMFS
HHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKAQSLDGLFEKLLDGKSIFKNKEVLRPSYTPDLLLHRNDQINSLATILVSALRGETPS
CCCCCHHHHHHHHHHCCHHHHCCCHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCC
NVLIYGKTGTGKTAVTRYVGKELERVSEDKSIFCSVVYINCEVIDTQYRLLANLARHFEE
CEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHH
EVPMTGWPTDQVFMKFKEAIDSREQVIIIILDEIDKLIKKGDDVLYNLSRINTDLRKAKV
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCHHEEHHHHHHHHHHHHHH
SMIGVSNDLKFTEFLDPRVKSSLGEEELIFPPYDAEQISDILKQRAKMAYNDGVLGEMVI
HEEECCCCCCHHHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
PLCAAFAAQEHGDARRALDLLRVSGEIAERENQPQVLEEHVRRAQEKIEIDRVVEVVRTL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PTQSKLVLYSIILLRNRGREGKNVTTGEMYNVYRQLCHHIDVDILTQRRVTDLMSELDML
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GIVNAVVVSKGRYGRTKEISLSVPVENTRKVLLEDYRLKPLVDFKASVFNKMFS
HHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]