| Definition | Methanosarcina mazei Go1 chromosome, complete genome. |
|---|---|
| Accession | NC_003901 |
| Length | 4,096,345 |
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The map label for this gene is hflB [C]
Identifier: 21227358
GI number: 21227358
Start: 1490611
End: 1492866
Strand: Reverse
Name: hflB [C]
Synonym: MM_1256
Alternate gene names: 21227358
Gene position: 1492866-1490611 (Counterclockwise)
Preceding gene: 21227359
Following gene: 21227357
Centisome position: 36.44
GC content: 47.78
Gene sequence:
>2256_bases ATGACTGAAGAAATTAATTTGAGAGTAGCTGAGGCTTATCATAAAGACGTGGGAAGGGGAATTGCAAGAATCGACACCCG TTTAATGCAGGAAATGGGACTTGTAAGCGGGGATATTATTGAGATTTCGGGCAGATCCAAAACCTACGCAATTGTCTGGC CAAACGTCGAACGTGGGCAGGAAAACAGGATCAGAATAGATGGAAACCTGCGGAGCAATGCAAAGGTAGGAATAGACGAC AGAGTCACTATTCAGAAGGTCCAGGCAAAGCATGCTCAGAGGGTTACACTTGCTCCATCCCAGCCTGTCAGGCTTGTGGG TGGTGCTCATTACATCCTGAGAATAATTGAGGGCAGACCTCTAAATAAAGGTCAGCAAATAAGGGTTGAAACCGTAAACA ACCCACTGACTTTCGTGGTCGCATCTACAAGACCTGCAGGTCCTGTTGTTGTTACCAAAGATACTGAAATCATCATTAAA GAAAAATCAATTGAAGAGATCAAGGCCCCTGAAGGTATATCCTACGAAGATATCGGAGGGCTCAGACGGGAAATCCAGCT TGTAAGGGAAATGATTGAGCTGCCAATGAGGCATCCTGAACTCTTCCAGAAGCTGGGTGTCGAGCCTCCAAAAGGAGTTC TTCTTCATGGACCTCCCGGAACGGGTAAGACCATGATTGCAAAGGCTGTCGCAAGTGAAACCGATGCCAATTTTATTACA ATCAGCGGTCCTGAAATCGTCTCCAAGTATTACGGAGAAAGCGAACAGAAACTCAGGGAAATCTTCGAAGAAGCCGAGAA GGATGCTCCTTCCATCATCTTCATAGACGAAATAGACTCAATCGCCCCTAAACGAGGCGAAGTCACCGGGGAAATGGAAA GAAGGGTTGTAGCCCAGCTGCTTTCCCTGATGGACGGGCTCAAGTCCAGGGGCGAAGTGGTGGTCATAGCTGCTACAAAC CGCCCGAACTCCATTGATGAAGCTCTCCGCCGCGGTGGAAGGTTTGACAGAGAGATCGAGATCGGAATACCTGACAGAAA CGGCAGGAAGCAGATTCTCCTGATCCATACTAGAGGCATGCCACTCGAAGATGAAGTGAGCCTCAGTGAGATCGCAGATG TGACCCATGGTTTTGTGGGAGCTGACCTCTCATCCCTCTGTAAGGAAGCTGCAATGCATGCACTCAGAAGGATCACTCCA GAAATTGATATCGAAGAGGAGATTCCACAGGAGATCATCGACAATCTTGTGGTCACAAAAGAAAATTTCAGAGAAGCCCT GAAAAATATTGAGCCTTCAGCCATGAGAGAAGTCTATATTGAAGTTCCGCATGTTGGCTGGGACGATATAGGCGGGCTTG AGAAAGCAAAACAGGAACTTATCGAGTCTGTGGAATGGCCTCTCAAATATCCTGAAATGTTCAAGGCTGTCAGTATAAAG CCTCCGAGAGGCGTCCTTCTCTTCGGGCCGCCGGGTACTGGTAAAACTTTGCTTGCAAAAGCTGTTGCAAATGAAAGTGA GGCTAATTTCATCAGCATTAAAGGCCCAGAACTCCTCAGCAAGTATGTGGGTGAATCCGAGCGTGCGATAAGGGAAACGT TCAGGAAAGCAAAACAGGCTGCTCCGACTGTAATCTTCTTTGATGAGATCGATTCCATTGCTCCTCAAAGAAGCTCTGTT TCCGACACGCATGTTTCCGAAAGAGTGGTCAGCCAGATCCTTACGGAACTTGACGGGATAGAAGAGCTGAAAGACGTAAT CATAGTCGCCGCTACAAACAGGCCGGATATGGTAGACCCTGCCCTTCTGAGGCCCGGCCGCTTTGACAGGCTCATCTACA TCAAGCCTCCTGGAAAAGAAGGAAGAGAGAAGATCTTTGAGATTCATGCGAAAGAAAAACCGCTTGCAGAAGATGTAAAA CTCTCTGAGCTCGCTGAGATGACCGAAGGGTATGTGGGTGCGGATATTGAAGGCATCTGCAGGGAAGCTGCAATGCTAGC CCTCAGGGAAATCGTCACTCCGGGTGCTGATAGGAAGAACATCCAGGAAAAGGCAGCAGAAGTCCGTCTTTCAAAAAGGC ACTTCGAAAAAGCGATCCGCCGTGTAAAGCCCACGACATCCAGAGAAACTCTGAGTGCCTATGAAAAGAGTGCTGAACTC TTTGCCAGGTACGCAACTGAGTTTGAGGAAGAGTCTTCAGAAGAAAAAGATCAGGAAATCAAGGTCGAAGAAAAAGATCA GGAAACCAGGGTCTAA
Upstream 100 bases:
>100_bases ACTCTAACCTTATGGATCTTGCAGAAAGAGGCTTTGTTGAGTATACGATCAAAAATAGCCAGCAGTACTGGAAAATATGT GAGACCGGAGTTGAAAATAA
Downstream 100 bases:
>100_bases GAAAAGATTCCTAAGAAAAAGATATCCGGATTTTCTGCAGGCAGATAAAACTTTATTTGACCAGCCGGTAAATTCCGGCA CTTTAATTTTTGCCAGGAAA
Product: CdcH protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 751; Mature: 750
Protein sequence:
>751_residues MTEEINLRVAEAYHKDVGRGIARIDTRLMQEMGLVSGDIIEISGRSKTYAIVWPNVERGQENRIRIDGNLRSNAKVGIDD RVTIQKVQAKHAQRVTLAPSQPVRLVGGAHYILRIIEGRPLNKGQQIRVETVNNPLTFVVASTRPAGPVVVTKDTEIIIK EKSIEEIKAPEGISYEDIGGLRREIQLVREMIELPMRHPELFQKLGVEPPKGVLLHGPPGTGKTMIAKAVASETDANFIT ISGPEIVSKYYGESEQKLREIFEEAEKDAPSIIFIDEIDSIAPKRGEVTGEMERRVVAQLLSLMDGLKSRGEVVVIAATN RPNSIDEALRRGGRFDREIEIGIPDRNGRKQILLIHTRGMPLEDEVSLSEIADVTHGFVGADLSSLCKEAAMHALRRITP EIDIEEEIPQEIIDNLVVTKENFREALKNIEPSAMREVYIEVPHVGWDDIGGLEKAKQELIESVEWPLKYPEMFKAVSIK PPRGVLLFGPPGTGKTLLAKAVANESEANFISIKGPELLSKYVGESERAIRETFRKAKQAAPTVIFFDEIDSIAPQRSSV SDTHVSERVVSQILTELDGIEELKDVIIVAATNRPDMVDPALLRPGRFDRLIYIKPPGKEGREKIFEIHAKEKPLAEDVK LSELAEMTEGYVGADIEGICREAAMLALREIVTPGADRKNIQEKAAEVRLSKRHFEKAIRRVKPTTSRETLSAYEKSAEL FARYATEFEEESSEEKDQEIKVEEKDQETRV
Sequences:
>Translated_751_residues MTEEINLRVAEAYHKDVGRGIARIDTRLMQEMGLVSGDIIEISGRSKTYAIVWPNVERGQENRIRIDGNLRSNAKVGIDD RVTIQKVQAKHAQRVTLAPSQPVRLVGGAHYILRIIEGRPLNKGQQIRVETVNNPLTFVVASTRPAGPVVVTKDTEIIIK EKSIEEIKAPEGISYEDIGGLRREIQLVREMIELPMRHPELFQKLGVEPPKGVLLHGPPGTGKTMIAKAVASETDANFIT ISGPEIVSKYYGESEQKLREIFEEAEKDAPSIIFIDEIDSIAPKRGEVTGEMERRVVAQLLSLMDGLKSRGEVVVIAATN RPNSIDEALRRGGRFDREIEIGIPDRNGRKQILLIHTRGMPLEDEVSLSEIADVTHGFVGADLSSLCKEAAMHALRRITP EIDIEEEIPQEIIDNLVVTKENFREALKNIEPSAMREVYIEVPHVGWDDIGGLEKAKQELIESVEWPLKYPEMFKAVSIK PPRGVLLFGPPGTGKTLLAKAVANESEANFISIKGPELLSKYVGESERAIRETFRKAKQAAPTVIFFDEIDSIAPQRSSV SDTHVSERVVSQILTELDGIEELKDVIIVAATNRPDMVDPALLRPGRFDRLIYIKPPGKEGREKIFEIHAKEKPLAEDVK LSELAEMTEGYVGADIEGICREAAMLALREIVTPGADRKNIQEKAAEVRLSKRHFEKAIRRVKPTTSRETLSAYEKSAEL FARYATEFEEESSEEKDQEIKVEEKDQETRV >Mature_750_residues TEEINLRVAEAYHKDVGRGIARIDTRLMQEMGLVSGDIIEISGRSKTYAIVWPNVERGQENRIRIDGNLRSNAKVGIDDR VTIQKVQAKHAQRVTLAPSQPVRLVGGAHYILRIIEGRPLNKGQQIRVETVNNPLTFVVASTRPAGPVVVTKDTEIIIKE KSIEEIKAPEGISYEDIGGLRREIQLVREMIELPMRHPELFQKLGVEPPKGVLLHGPPGTGKTMIAKAVASETDANFITI SGPEIVSKYYGESEQKLREIFEEAEKDAPSIIFIDEIDSIAPKRGEVTGEMERRVVAQLLSLMDGLKSRGEVVVIAATNR PNSIDEALRRGGRFDREIEIGIPDRNGRKQILLIHTRGMPLEDEVSLSEIADVTHGFVGADLSSLCKEAAMHALRRITPE IDIEEEIPQEIIDNLVVTKENFREALKNIEPSAMREVYIEVPHVGWDDIGGLEKAKQELIESVEWPLKYPEMFKAVSIKP PRGVLLFGPPGTGKTLLAKAVANESEANFISIKGPELLSKYVGESERAIRETFRKAKQAAPTVIFFDEIDSIAPQRSSVS DTHVSERVVSQILTELDGIEELKDVIIVAATNRPDMVDPALLRPGRFDRLIYIKPPGKEGREKIFEIHAKEKPLAEDVKL SELAEMTEGYVGADIEGICREAAMLALREIVTPGADRKNIQEKAAEVRLSKRHFEKAIRRVKPTTSRETLSAYEKSAELF ARYATEFEEESSEEKDQEIKVEEKDQETRV
Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving
COG id: COG0464
COG function: function code O; ATPases of the AAA+ class
Gene ontology:
Cell location: Integral Membrane Protein. Inner Membrane [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the AAA ATPase family. CDC48 subfamily [H]
Homologues:
Organism=Homo sapiens, GI6005942, Length=739, Percent_Identity=46.4140730717185, Blast_Score=637, Evalue=0.0, Organism=Homo sapiens, GI157671927, Length=553, Percent_Identity=52.0795660036166, Blast_Score=570, Evalue=1e-162, Organism=Homo sapiens, GI45643125, Length=602, Percent_Identity=45.6810631229236, Blast_Score=511, Evalue=1e-144, Organism=Homo sapiens, GI45643123, Length=602, Percent_Identity=45.6810631229236, Blast_Score=511, Evalue=1e-144, Organism=Homo sapiens, GI229577436, Length=544, Percent_Identity=43.0147058823529, Blast_Score=437, Evalue=1e-122, Organism=Homo sapiens, GI4505725, Length=481, Percent_Identity=36.3825363825364, Blast_Score=298, Evalue=1e-80, Organism=Homo sapiens, GI194018488, Length=523, Percent_Identity=34.7992351816444, Blast_Score=283, Evalue=3e-76, Organism=Homo sapiens, GI153792536, Length=281, Percent_Identity=43.0604982206406, Blast_Score=248, Evalue=1e-65, Organism=Homo sapiens, GI24497618, Length=281, Percent_Identity=42.3487544483986, Blast_Score=244, Evalue=3e-64, Organism=Homo sapiens, GI24430151, Length=330, Percent_Identity=39.6969696969697, Blast_Score=232, Evalue=1e-60, Organism=Homo sapiens, GI24497435, Length=306, Percent_Identity=39.8692810457516, Blast_Score=228, Evalue=2e-59, Organism=Homo sapiens, GI21361144, Length=274, Percent_Identity=43.0656934306569, Blast_Score=216, Evalue=5e-56, Organism=Homo sapiens, GI195539395, Length=267, Percent_Identity=42.3220973782771, Blast_Score=216, Evalue=5e-56, Organism=Homo sapiens, GI4506209, Length=242, Percent_Identity=44.6280991735537, Blast_Score=215, Evalue=1e-55, Organism=Homo sapiens, GI24430155, Length=231, Percent_Identity=45.4545454545455, Blast_Score=210, Evalue=4e-54, Organism=Homo sapiens, GI5729991, Length=231, Percent_Identity=45.4545454545455, Blast_Score=210, Evalue=5e-54, Organism=Homo sapiens, GI89064750, Length=231, Percent_Identity=45.4545454545455, Blast_Score=209, Evalue=8e-54, Organism=Homo sapiens, GI5901990, Length=291, Percent_Identity=40.893470790378, Blast_Score=209, Evalue=9e-54, Organism=Homo sapiens, GI300192933, Length=264, Percent_Identity=40.9090909090909, Blast_Score=205, Evalue=2e-52, Organism=Homo sapiens, GI14149767, Length=291, Percent_Identity=39.8625429553265, Blast_Score=202, Evalue=7e-52, Organism=Homo sapiens, GI62177112, Length=291, Percent_Identity=39.8625429553265, Blast_Score=202, Evalue=7e-52, Organism=Homo sapiens, GI31742536, Length=306, Percent_Identity=37.2549019607843, Blast_Score=188, Evalue=1e-47, Organism=Homo sapiens, GI112789543, Length=306, Percent_Identity=37.2549019607843, Blast_Score=188, Evalue=1e-47, Organism=Homo sapiens, GI156564401, Length=403, Percent_Identity=34.4913151364764, Blast_Score=188, Evalue=1e-47, Organism=Homo sapiens, GI4507173, Length=272, Percent_Identity=38.6029411764706, Blast_Score=186, Evalue=5e-47, Organism=Homo sapiens, GI11875211, Length=298, Percent_Identity=37.9194630872483, Blast_Score=185, Evalue=1e-46, Organism=Homo sapiens, GI40806170, Length=298, Percent_Identity=37.9194630872483, Blast_Score=185, Evalue=1e-46, Organism=Homo sapiens, GI226371754, Length=247, Percent_Identity=38.8663967611336, Blast_Score=184, Evalue=4e-46, Organism=Homo sapiens, GI7019569, Length=247, Percent_Identity=38.8663967611336, Blast_Score=182, Evalue=1e-45, Organism=Homo sapiens, GI17865802, Length=238, Percent_Identity=40.3361344537815, Blast_Score=173, Evalue=4e-43, Organism=Homo sapiens, GI7657689, Length=291, Percent_Identity=36.426116838488, Blast_Score=171, Evalue=3e-42, Organism=Homo sapiens, GI21327685, Length=291, Percent_Identity=36.426116838488, Blast_Score=171, Evalue=3e-42, Organism=Homo sapiens, GI31377644, Length=268, Percent_Identity=35.8208955223881, Blast_Score=169, Evalue=9e-42, Organism=Homo sapiens, GI310125280, Length=273, Percent_Identity=35.5311355311355, Blast_Score=162, Evalue=9e-40, Organism=Homo sapiens, GI310125282, Length=272, Percent_Identity=38.2352941176471, Blast_Score=160, Evalue=4e-39, Organism=Homo sapiens, GI64084766, Length=313, Percent_Identity=29.3929712460064, Blast_Score=141, Evalue=2e-33, Organism=Homo sapiens, GI40806173, Length=148, Percent_Identity=39.8648648648649, Blast_Score=112, Evalue=1e-24, Organism=Homo sapiens, GI116292174, Length=295, Percent_Identity=27.1186440677966, Blast_Score=111, Evalue=3e-24, Organism=Homo sapiens, GI11321607, Length=228, Percent_Identity=29.3859649122807, Blast_Score=76, Evalue=9e-14, Organism=Homo sapiens, GI40255052, Length=187, Percent_Identity=28.3422459893048, Blast_Score=71, Evalue=4e-12, Organism=Escherichia coli, GI1789568, Length=223, Percent_Identity=44.8430493273543, Blast_Score=202, Evalue=6e-53, Organism=Caenorhabditis elegans, GI17532375, Length=723, Percent_Identity=46.4730290456432, Blast_Score=634, Evalue=0.0, Organism=Caenorhabditis elegans, GI17531535, Length=721, Percent_Identity=45.4923717059639, Blast_Score=624, Evalue=1e-179, Organism=Caenorhabditis elegans, GI17537217, Length=614, Percent_Identity=38.599348534202, Blast_Score=420, Evalue=1e-117, Organism=Caenorhabditis elegans, GI17508053, Length=542, Percent_Identity=36.5313653136531, Blast_Score=314, Evalue=1e-85, Organism=Caenorhabditis elegans, GI17562804, Length=498, Percent_Identity=33.3333333333333, Blast_Score=240, Evalue=3e-63, Organism=Caenorhabditis elegans, GI193206116, Length=284, Percent_Identity=42.9577464788732, Blast_Score=236, Evalue=5e-62, Organism=Caenorhabditis elegans, GI193206114, Length=284, Percent_Identity=42.9577464788732, Blast_Score=235, Evalue=6e-62, Organism=Caenorhabditis elegans, GI133931034, Length=284, Percent_Identity=42.9577464788732, Blast_Score=235, Evalue=6e-62, Organism=Caenorhabditis elegans, GI17563250, Length=296, Percent_Identity=41.2162162162162, Blast_Score=225, Evalue=6e-59, Organism=Caenorhabditis elegans, GI17554786, Length=275, Percent_Identity=41.4545454545455, Blast_Score=225, Evalue=8e-59, Organism=Caenorhabditis elegans, GI71987364, Length=300, Percent_Identity=40, Blast_Score=225, Evalue=9e-59, Organism=Caenorhabditis elegans, GI71987372, Length=300, Percent_Identity=40, Blast_Score=224, Evalue=1e-58, Organism=Caenorhabditis elegans, GI25153574, Length=475, Percent_Identity=33.2631578947368, Blast_Score=218, Evalue=8e-57, Organism=Caenorhabditis elegans, GI25144278, Length=275, Percent_Identity=40, Blast_Score=217, Evalue=2e-56, Organism=Caenorhabditis elegans, GI25144281, Length=275, Percent_Identity=40, Blast_Score=216, Evalue=3e-56, Organism=Caenorhabditis elegans, GI17563248, Length=242, Percent_Identity=42.9752066115703, Blast_Score=213, Evalue=4e-55, Organism=Caenorhabditis elegans, GI17508701, Length=270, Percent_Identity=42.2222222222222, Blast_Score=212, Evalue=5e-55, Organism=Caenorhabditis elegans, GI17505546, Length=226, Percent_Identity=45.575221238938, Blast_Score=211, Evalue=1e-54, Organism=Caenorhabditis elegans, GI17554784, Length=241, Percent_Identity=46.0580912863071, Blast_Score=202, Evalue=8e-52, Organism=Caenorhabditis elegans, GI193209502, Length=226, Percent_Identity=46.0176991150442, Blast_Score=201, Evalue=1e-51, Organism=Caenorhabditis elegans, GI71994521, Length=272, Percent_Identity=39.7058823529412, Blast_Score=188, Evalue=9e-48, Organism=Caenorhabditis elegans, GI25146157, Length=286, Percent_Identity=38.4615384615385, Blast_Score=183, Evalue=2e-46, Organism=Caenorhabditis elegans, GI17508421, Length=292, Percent_Identity=40.0684931506849, Blast_Score=179, Evalue=6e-45, Organism=Caenorhabditis elegans, GI32563584, Length=298, Percent_Identity=39.5973154362416, Blast_Score=177, Evalue=2e-44, Organism=Caenorhabditis elegans, GI133901662, Length=412, Percent_Identity=32.7669902912621, Blast_Score=174, Evalue=1e-43, Organism=Caenorhabditis elegans, GI133901658, Length=412, Percent_Identity=32.7669902912621, Blast_Score=174, Evalue=2e-43, Organism=Caenorhabditis elegans, GI86561515, Length=237, Percent_Identity=39.2405063291139, Blast_Score=169, Evalue=5e-42, Organism=Caenorhabditis elegans, GI17560432, Length=282, Percent_Identity=38.2978723404255, Blast_Score=167, Evalue=1e-41, Organism=Caenorhabditis elegans, GI17554264, Length=215, Percent_Identity=41.3953488372093, Blast_Score=167, Evalue=3e-41, Organism=Caenorhabditis elegans, GI115534323, Length=256, Percent_Identity=38.671875, Blast_Score=160, Evalue=3e-39, Organism=Caenorhabditis elegans, GI17541226, Length=317, Percent_Identity=31.2302839116719, Blast_Score=155, Evalue=6e-38, Organism=Caenorhabditis elegans, GI17541224, Length=222, Percent_Identity=36.4864864864865, Blast_Score=154, Evalue=1e-37, Organism=Caenorhabditis elegans, GI71990294, Length=195, Percent_Identity=28.2051282051282, Blast_Score=75, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17570397, Length=103, Percent_Identity=38.8349514563107, Blast_Score=70, Evalue=3e-12, Organism=Caenorhabditis elegans, GI32566590, Length=103, Percent_Identity=38.8349514563107, Blast_Score=70, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6320077, Length=752, Percent_Identity=45.4787234042553, Blast_Score=621, Evalue=1e-178, Organism=Saccharomyces cerevisiae, GI6323429, Length=556, Percent_Identity=50.8992805755396, Blast_Score=535, Evalue=1e-152, Organism=Saccharomyces cerevisiae, GI6322994, Length=639, Percent_Identity=40.8450704225352, Blast_Score=471, Evalue=1e-133, Organism=Saccharomyces cerevisiae, GI6324000, Length=566, Percent_Identity=31.8021201413428, Blast_Score=254, Evalue=4e-68, Organism=Saccharomyces cerevisiae, GI6322651, Length=503, Percent_Identity=31.8091451292247, Blast_Score=245, Evalue=2e-65, Organism=Saccharomyces cerevisiae, GI6321709, Length=274, Percent_Identity=44.5255474452555, Blast_Score=237, Evalue=6e-63, Organism=Saccharomyces cerevisiae, GI6321390, Length=233, Percent_Identity=47.2103004291845, Blast_Score=229, Evalue=2e-60, Organism=Saccharomyces cerevisiae, GI6320197, Length=226, Percent_Identity=47.3451327433628, Blast_Score=216, Evalue=8e-57, Organism=Saccharomyces cerevisiae, GI6322704, Length=227, Percent_Identity=44.9339207048458, Blast_Score=212, Evalue=2e-55, Organism=Saccharomyces cerevisiae, GI6324833, Length=291, Percent_Identity=40.893470790378, Blast_Score=209, Evalue=1e-54, Organism=Saccharomyces cerevisiae, GI6324691, Length=265, Percent_Identity=41.1320754716981, Blast_Score=204, Evalue=4e-53, Organism=Saccharomyces cerevisiae, GI6320602, Length=235, Percent_Identity=45.1063829787234, Blast_Score=201, Evalue=4e-52, Organism=Saccharomyces cerevisiae, GI6320854, Length=339, Percent_Identity=36.5781710914454, Blast_Score=200, Evalue=8e-52, Organism=Saccharomyces cerevisiae, GI6323736, Length=264, Percent_Identity=41.2878787878788, Blast_Score=191, Evalue=5e-49, Organism=Saccharomyces cerevisiae, GI6320887, Length=365, Percent_Identity=33.972602739726, Blast_Score=187, Evalue=7e-48, Organism=Saccharomyces cerevisiae, GI6319554, Length=407, Percent_Identity=33.1695331695332, Blast_Score=186, Evalue=9e-48, Organism=Saccharomyces cerevisiae, GI6325183, Length=322, Percent_Identity=35.0931677018634, Blast_Score=182, Evalue=1e-46, Organism=Saccharomyces cerevisiae, GI6325431, Length=335, Percent_Identity=33.4328358208955, Blast_Score=182, Evalue=2e-46, Organism=Saccharomyces cerevisiae, GI6321465, Length=235, Percent_Identity=42.1276595744681, Blast_Score=179, Evalue=1e-45, Organism=Saccharomyces cerevisiae, GI6325281, Length=297, Percent_Identity=36.3636363636364, Blast_Score=179, Evalue=2e-45, Organism=Saccharomyces cerevisiae, GI9755327, Length=176, Percent_Identity=30.6818181818182, Blast_Score=72, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6320583, Length=150, Percent_Identity=29.3333333333333, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI161076486, Length=739, Percent_Identity=45.7374830852503, Blast_Score=635, Evalue=0.0, Organism=Drosophila melanogaster, GI17137560, Length=739, Percent_Identity=45.7374830852503, Blast_Score=635, Evalue=0.0, Organism=Drosophila melanogaster, GI161076488, Length=717, Percent_Identity=46.4435146443515, Blast_Score=634, Evalue=0.0, Organism=Drosophila melanogaster, GI19921202, Length=718, Percent_Identity=36.4902506963788, Blast_Score=425, Evalue=1e-119, Organism=Drosophila melanogaster, GI45552965, Length=322, Percent_Identity=47.2049689440994, Blast_Score=301, Evalue=2e-81, Organism=Drosophila melanogaster, GI281365776, Length=322, Percent_Identity=47.2049689440994, Blast_Score=300, Evalue=2e-81, Organism=Drosophila melanogaster, GI24660075, Length=322, Percent_Identity=47.2049689440994, Blast_Score=300, Evalue=2e-81, Organism=Drosophila melanogaster, GI24656825, Length=532, Percent_Identity=32.5187969924812, Blast_Score=262, Evalue=8e-70, Organism=Drosophila melanogaster, GI21355121, Length=536, Percent_Identity=31.7164179104478, Blast_Score=259, Evalue=4e-69, Organism=Drosophila melanogaster, GI24656820, Length=551, Percent_Identity=31.3974591651543, Blast_Score=254, Evalue=1e-67, Organism=Drosophila melanogaster, GI281363136, Length=587, Percent_Identity=31.6865417376491, Blast_Score=237, Evalue=2e-62, Organism=Drosophila melanogaster, GI78707192, Length=587, Percent_Identity=31.6865417376491, Blast_Score=237, Evalue=2e-62, Organism=Drosophila melanogaster, GI24652279, Length=254, Percent_Identity=46.0629921259843, Blast_Score=232, Evalue=6e-61, Organism=Drosophila melanogaster, GI24649446, Length=296, Percent_Identity=42.5675675675676, Blast_Score=231, Evalue=1e-60, Organism=Drosophila melanogaster, GI19920408, Length=306, Percent_Identity=40.1960784313725, Blast_Score=231, Evalue=1e-60, Organism=Drosophila melanogaster, GI24651451, Length=274, Percent_Identity=42.3357664233577, Blast_Score=227, Evalue=2e-59, Organism=Drosophila melanogaster, GI17137738, Length=246, Percent_Identity=43.9024390243902, Blast_Score=219, Evalue=4e-57, Organism=Drosophila melanogaster, GI18860063, Length=233, Percent_Identity=45.9227467811159, Blast_Score=217, Evalue=2e-56, Organism=Drosophila melanogaster, GI281361487, Length=233, Percent_Identity=45.0643776824034, Blast_Score=216, Evalue=7e-56, Organism=Drosophila melanogaster, GI24640100, Length=230, Percent_Identity=46.5217391304348, Blast_Score=216, Evalue=7e-56, Organism=Drosophila melanogaster, GI17738151, Length=231, Percent_Identity=43.2900432900433, Blast_Score=214, Evalue=1e-55, Organism=Drosophila melanogaster, GI24663015, Length=264, Percent_Identity=40.9090909090909, Blast_Score=210, Evalue=3e-54, Organism=Drosophila melanogaster, GI24644145, Length=294, Percent_Identity=40.4761904761905, Blast_Score=207, Evalue=3e-53, Organism=Drosophila melanogaster, GI24581396, Length=283, Percent_Identity=40.2826855123675, Blast_Score=197, Evalue=3e-50, Organism=Drosophila melanogaster, GI24665814, Length=270, Percent_Identity=40, Blast_Score=196, Evalue=7e-50, Organism=Drosophila melanogaster, GI28574878, Length=262, Percent_Identity=40.8396946564886, Blast_Score=195, Evalue=9e-50, Organism=Drosophila melanogaster, GI17864540, Length=411, Percent_Identity=34.0632603406326, Blast_Score=189, Evalue=8e-48, Organism=Drosophila melanogaster, GI24658770, Length=224, Percent_Identity=44.1964285714286, Blast_Score=188, Evalue=1e-47, Organism=Drosophila melanogaster, GI281360146, Length=287, Percent_Identity=36.5853658536585, Blast_Score=186, Evalue=4e-47, Organism=Drosophila melanogaster, GI281360138, Length=287, Percent_Identity=36.5853658536585, Blast_Score=186, Evalue=4e-47, Organism=Drosophila melanogaster, GI281360142, Length=287, Percent_Identity=36.5853658536585, Blast_Score=186, Evalue=5e-47, Organism=Drosophila melanogaster, GI21357333, Length=287, Percent_Identity=36.5853658536585, Blast_Score=186, Evalue=5e-47, Organism=Drosophila melanogaster, GI281360136, Length=287, Percent_Identity=36.5853658536585, Blast_Score=186, Evalue=6e-47, Organism=Drosophila melanogaster, GI24644411, Length=287, Percent_Identity=36.5853658536585, Blast_Score=186, Evalue=6e-47, Organism=Drosophila melanogaster, GI281360144, Length=287, Percent_Identity=36.5853658536585, Blast_Score=186, Evalue=6e-47, Organism=Drosophila melanogaster, GI281360140, Length=287, Percent_Identity=36.5853658536585, Blast_Score=186, Evalue=6e-47, Organism=Drosophila melanogaster, GI24639391, Length=232, Percent_Identity=43.9655172413793, Blast_Score=185, Evalue=1e-46, Organism=Drosophila melanogaster, GI28573010, Length=412, Percent_Identity=33.495145631068, Blast_Score=183, Evalue=5e-46, Organism=Drosophila melanogaster, GI28571849, Length=315, Percent_Identity=37.4603174603175, Blast_Score=177, Evalue=3e-44, Organism=Drosophila melanogaster, GI28571847, Length=315, Percent_Identity=37.4603174603175, Blast_Score=177, Evalue=3e-44, Organism=Drosophila melanogaster, GI18859657, Length=239, Percent_Identity=41.0041841004184, Blast_Score=176, Evalue=4e-44, Organism=Drosophila melanogaster, GI20129529, Length=246, Percent_Identity=40.650406504065, Blast_Score=174, Evalue=2e-43, Organism=Drosophila melanogaster, GI20129423, Length=253, Percent_Identity=37.1541501976285, Blast_Score=171, Evalue=2e-42, Organism=Drosophila melanogaster, GI24639486, Length=236, Percent_Identity=38.135593220339, Blast_Score=155, Evalue=9e-38, Organism=Drosophila melanogaster, GI45554047, Length=164, Percent_Identity=41.4634146341463, Blast_Score=132, Evalue=7e-31, Organism=Drosophila melanogaster, GI28573181, Length=165, Percent_Identity=30.3030303030303, Blast_Score=78, Evalue=3e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR009010 - InterPro: IPR003593 - InterPro: IPR005938 - InterPro: IPR003959 - InterPro: IPR003960 - InterPro: IPR003338 - InterPro: IPR004201 - InterPro: IPR015415 [H]
Pfam domain/function: PF00004 AAA; PF02933 CDC48_2; PF02359 CDC48_N; PF09336 Vps4_C [H]
EC number: 3.4.24.- [C]
Molecular weight: Translated: 83907; Mature: 83776
Theoretical pI: Translated: 5.15; Mature: 5.15
Prosite motif: PS00674 AAA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTEEINLRVAEAYHKDVGRGIARIDTRLMQEMGLVSGDIIEISGRSKTYAIVWPNVERGQ CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCCCCC ENRIRIDGNLRSNAKVGIDDRVTIQKVQAKHAQRVTLAPSQPVRLVGGAHYILRIIEGRP CCEEEECCCCCCCCEECCCCCHHHHHHHHHHCCEEEECCCCCEEECCCHHHHHHHHCCCC LNKGQQIRVETVNNPLTFVVASTRPAGPVVVTKDTEIIIKEKSIEEIKAPEGISYEDIGG CCCCCEEEEEECCCCEEEEEECCCCCCCEEEECCCEEEEECCCHHHHCCCCCCCHHHHHH LRREIQLVREMIELPMRHPELFQKLGVEPPKGVLLHGPPGTGKTMIAKAVASETDANFIT HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEE ISGPEIVSKYYGESEQKLREIFEEAEKDAPSIIFIDEIDSIAPKRGEVTGEMERRVVAQL ECCHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH LSLMDGLKSRGEVVVIAATNRPNSIDEALRRGGRFDREIEIGIPDRNGRKQILLIHTRGM HHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEEEECCC PLEDEVSLSEIADVTHGFVGADLSSLCKEAAMHALRRITPEIDIEEEIPQEIIDNLVVTK CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCH ENFREALKNIEPSAMREVYIEVPHVGWDDIGGLEKAKQELIESVEWPLKYPEMFKAVSIK HHHHHHHHCCCHHHHHHEEEECCCCCCHHCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCC PPRGVLLFGPPGTGKTLLAKAVANESEANFISIKGPELLSKYVGESERAIRETFRKAKQA CCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCHHHHHHHHHHHHHHC APTVIFFDEIDSIAPQRSSVSDTHVSERVVSQILTELDGIEELKDVIIVAATNRPDMVDP CCEEEEECCHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCEEEEEECCCCCCCCH ALLRPGRFDRLIYIKPPGKEGREKIFEIHAKEKPLAEDVKLSELAEMTEGYVGADIEGIC HHCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCHHHCCHHHHHHHHCCCCCCCHHHHH REAAMLALREIVTPGADRKNIQEKAAEVRLSKRHFEKAIRRVKPTTSRETLSAYEKSAEL HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH FARYATEFEEESSEEKDQEIKVEEKDQETRV HHHHHHHHHHHCCHHHHHCCCCCCCHHCCCC >Mature Secondary Structure TEEINLRVAEAYHKDVGRGIARIDTRLMQEMGLVSGDIIEISGRSKTYAIVWPNVERGQ CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCCCCC ENRIRIDGNLRSNAKVGIDDRVTIQKVQAKHAQRVTLAPSQPVRLVGGAHYILRIIEGRP CCEEEECCCCCCCCEECCCCCHHHHHHHHHHCCEEEECCCCCEEECCCHHHHHHHHCCCC LNKGQQIRVETVNNPLTFVVASTRPAGPVVVTKDTEIIIKEKSIEEIKAPEGISYEDIGG CCCCCEEEEEECCCCEEEEEECCCCCCCEEEECCCEEEEECCCHHHHCCCCCCCHHHHHH LRREIQLVREMIELPMRHPELFQKLGVEPPKGVLLHGPPGTGKTMIAKAVASETDANFIT HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEE ISGPEIVSKYYGESEQKLREIFEEAEKDAPSIIFIDEIDSIAPKRGEVTGEMERRVVAQL ECCHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH LSLMDGLKSRGEVVVIAATNRPNSIDEALRRGGRFDREIEIGIPDRNGRKQILLIHTRGM HHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEEEECCC PLEDEVSLSEIADVTHGFVGADLSSLCKEAAMHALRRITPEIDIEEEIPQEIIDNLVVTK CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCH ENFREALKNIEPSAMREVYIEVPHVGWDDIGGLEKAKQELIESVEWPLKYPEMFKAVSIK HHHHHHHHCCCHHHHHHEEEECCCCCCHHCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCC PPRGVLLFGPPGTGKTLLAKAVANESEANFISIKGPELLSKYVGESERAIRETFRKAKQA CCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCHHHHHHHHHHHHHHC APTVIFFDEIDSIAPQRSSVSDTHVSERVVSQILTELDGIEELKDVIIVAATNRPDMVDP CCEEEEECCHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCEEEEEECCCCCCCCH ALLRPGRFDRLIYIKPPGKEGREKIFEIHAKEKPLAEDVKLSELAEMTEGYVGADIEGIC HHCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCHHHCCHHHHHHHHCCCCCCCHHHHH REAAMLALREIVTPGADRKNIQEKAAEVRLSKRHFEKAIRRVKPTTSRETLSAYEKSAEL HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH FARYATEFEEESSEEKDQEIKVEEKDQETRV HHHHHHHHHHHCCHHHHHCCCCCCCHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9389475 [H]