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The map label for this gene is wcaL [C]

Identifier: 21227244

GI number: 21227244

Start: 1351948

End: 1353087

Strand: Direct

Name: wcaL [C]

Synonym: MM_1142

Alternate gene names: 21227244

Gene position: 1351948-1353087 (Clockwise)

Preceding gene: 21227243

Following gene: 21227245

Centisome position: 33.0

GC content: 33.51

Gene sequence:

>1140_bases
ATGAAAATCTGCATGTATACTTCTGAGTTCCCGCCTGATATAGGTGGTATAAGCACTTATGTCTATAATTTATCAAAAAA
ACTTGTAGAAAGAGGACATGAAGTCACAGTCATTACAAGAGGAACCTGGAGAAAAACATATTATGAAAAGATAGAGGGGA
TTTCTGTTTATAGAGTAAGATTTATCCCGTTTTTTCCATCTCCGTTTAAAATTCACGAAATATATGTTACTAAACTGTTA
AAATCATTAAAATTTGACTTTGATTTGATCCATTTGCATGGATATTTTCTGCCAGTTAAGCCAGTATTTAACAGTTCGCT
GCCTGTTATATTCACTTCACACGGTAATTCTACAAAAAAGCTTGATTCTATGGAAGTAAAAACTCTACATTTCTTTATTG
TAAAACTATTACGCAAATATTTATTTAAAGTGGAACAGGAAATTGTTCAGAAAAGTGATATATTAACAGCTGTATCAAAT
TCATCTGCTAATAATTTTAGAATGTACCATTCAATTAAAAGGGAGATAAGTATAGTTCATAACGGAGTAGATACTGATTT
CTTTACCCCCCCCGAAAATAGATCAAATTTAAAATCCGTTTTATATACCGGCAGATTTGAAGTGTTTAAAGGTTTATTCG
ACTTAATCGAATGTTCAAGCATTGTGTGCAAAAAATATCCAGATGTCAAGTTTATTTTAGTGGGTACAGGGACCATACTG
GAGAATTTAAAAAAACAGGTAAAAAAACTTGGACTGGAAGATAATGTCATATTCACCGGTTCTTTAAGTAGATCACAGAT
TATCGAATATTACAAAAATGCAACTATTTTCGTATTGCCTTCCTATAGAGAAGGATTCCCAACAAGTCTAATGGAGGCTA
TGTCCTGCGGGGTACCTTCGGTTGCGACAGATGTTGAAGGGTGTGACGAGTTAATAGAGGATGGTGAAAATGGTATACTG
GTTCCTCCGAAAAATCCTGAAAAACTAGCTGAATCAATAATATATCTGTTAGAAAATGAAGAATTCAGAAATAGAATAGG
GATCAATGCCAGAGACCATATTGTGAGAAACTATGACTGGGAAACAATTACAGATGGTTTTGAAAAATTATATTATCGAC
TGTCCTCCAGGGATGCATGA

Upstream 100 bases:

>100_bases
CAGTAATCACATTTTGAGAAAAACACTTTCCGAGACAAAAATATGTTATTTTATGGAATTAAAACGATCTTTTTTCACTT
AATAATATAGGACAAAAATT

Downstream 100 bases:

>100_bases
TTTTATCCTTTTTTCGCCAGTAAATCTTCAAAAGCTATTTTCTAACTGACTGTATTTTGAGAATATGCAATAAATGGGAA
GTAGTAACAGAAAATAACAA

Product: glycosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKICMYTSEFPPDIGGISTYVYNLSKKLVERGHEVTVITRGTWRKTYYEKIEGISVYRVRFIPFFPSPFKIHEIYVTKLL
KSLKFDFDLIHLHGYFLPVKPVFNSSLPVIFTSHGNSTKKLDSMEVKTLHFFIVKLLRKYLFKVEQEIVQKSDILTAVSN
SSANNFRMYHSIKREISIVHNGVDTDFFTPPENRSNLKSVLYTGRFEVFKGLFDLIECSSIVCKKYPDVKFILVGTGTIL
ENLKKQVKKLGLEDNVIFTGSLSRSQIIEYYKNATIFVLPSYREGFPTSLMEAMSCGVPSVATDVEGCDELIEDGENGIL
VPPKNPEKLAESIIYLLENEEFRNRIGINARDHIVRNYDWETITDGFEKLYYRLSSRDA

Sequences:

>Translated_379_residues
MKICMYTSEFPPDIGGISTYVYNLSKKLVERGHEVTVITRGTWRKTYYEKIEGISVYRVRFIPFFPSPFKIHEIYVTKLL
KSLKFDFDLIHLHGYFLPVKPVFNSSLPVIFTSHGNSTKKLDSMEVKTLHFFIVKLLRKYLFKVEQEIVQKSDILTAVSN
SSANNFRMYHSIKREISIVHNGVDTDFFTPPENRSNLKSVLYTGRFEVFKGLFDLIECSSIVCKKYPDVKFILVGTGTIL
ENLKKQVKKLGLEDNVIFTGSLSRSQIIEYYKNATIFVLPSYREGFPTSLMEAMSCGVPSVATDVEGCDELIEDGENGIL
VPPKNPEKLAESIIYLLENEEFRNRIGINARDHIVRNYDWETITDGFEKLYYRLSSRDA
>Mature_379_residues
MKICMYTSEFPPDIGGISTYVYNLSKKLVERGHEVTVITRGTWRKTYYEKIEGISVYRVRFIPFFPSPFKIHEIYVTKLL
KSLKFDFDLIHLHGYFLPVKPVFNSSLPVIFTSHGNSTKKLDSMEVKTLHFFIVKLLRKYLFKVEQEIVQKSDILTAVSN
SSANNFRMYHSIKREISIVHNGVDTDFFTPPENRSNLKSVLYTGRFEVFKGLFDLIECSSIVCKKYPDVKFILVGTGTIL
ENLKKQVKKLGLEDNVIFTGSLSRSQIIEYYKNATIFVLPSYREGFPTSLMEAMSCGVPSVATDVEGCDELIEDGENGIL
VPPKNPEKLAESIIYLLENEEFRNRIGINARDHIVRNYDWETITDGFEKLYYRLSSRDA

Specific function: Slime polysaccharide colanic acid biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=398, Percent_Identity=27.3869346733668, Blast_Score=108, Evalue=6e-24,
Organism=Escherichia coli, GI1788357, Length=185, Percent_Identity=26.4864864864865, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17532709, Length=386, Percent_Identity=26.4248704663212, Blast_Score=105, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI9755344, Length=395, Percent_Identity=23.7974683544304, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24654571, Length=360, Percent_Identity=25.2777777777778, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR013534 [H]

Pfam domain/function: PF08323 Glyco_transf_5; PF00534 Glycos_transf_1 [H]

EC number: 2.-.-.- [C]

Molecular weight: Translated: 43657; Mature: 43657

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKICMYTSEFPPDIGGISTYVYNLSKKLVERGHEVTVITRGTWRKTYYEKIEGISVYRVR
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCEEEEEE
FIPFFPSPFKIHEIYVTKLLKSLKFDFDLIHLHGYFLPVKPVFNSSLPVIFTSHGNSTKK
EEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEECEEEEECHHHCCCCCEEEECCCCCCCC
LDSMEVKTLHFFIVKLLRKYLFKVEQEIVQKSDILTAVSNSSANNFRMYHSIKREISIVH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
NGVDTDFFTPPENRSNLKSVLYTGRFEVFKGLFDLIECSSIVCKKYPDVKFILVGTGTIL
CCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHH
ENLKKQVKKLGLEDNVIFTGSLSRSQIIEYYKNATIFVLPSYREGFPTSLMEAMSCGVPS
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCC
VATDVEGCDELIEDGENGILVPPKNPEKLAESIIYLLENEEFRNRIGINARDHIVRNYDW
HHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHCCCCC
ETITDGFEKLYYRLSSRDA
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKICMYTSEFPPDIGGISTYVYNLSKKLVERGHEVTVITRGTWRKTYYEKIEGISVYRVR
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCEEEEEE
FIPFFPSPFKIHEIYVTKLLKSLKFDFDLIHLHGYFLPVKPVFNSSLPVIFTSHGNSTKK
EEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEECEEEEECHHHCCCCCEEEECCCCCCCC
LDSMEVKTLHFFIVKLLRKYLFKVEQEIVQKSDILTAVSNSSANNFRMYHSIKREISIVH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
NGVDTDFFTPPENRSNLKSVLYTGRFEVFKGLFDLIECSSIVCKKYPDVKFILVGTGTIL
CCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHH
ENLKKQVKKLGLEDNVIFTGSLSRSQIIEYYKNATIFVLPSYREGFPTSLMEAMSCGVPS
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCC
VATDVEGCDELIEDGENGILVPPKNPEKLAESIIYLLENEEFRNRIGINARDHIVRNYDW
HHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHCCCCC
ETITDGFEKLYYRLSSRDA
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]