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The map label for this gene is gtaB [H]

Identifier: 21227235

GI number: 21227235

Start: 1336385

End: 1337356

Strand: Reverse

Name: gtaB [H]

Synonym: MM_1133

Alternate gene names: 21227235

Gene position: 1337356-1336385 (Counterclockwise)

Preceding gene: 21227237

Following gene: 21227233

Centisome position: 32.65

GC content: 43.21

Gene sequence:

>972_bases
ATGGGTGAAAAGTACTTTAACTCAGAAGAATACAACCTTACAGAATTTCTTTTCATTGGAGAATTAACCTTGACTATCAA
AAAAGCACTTATCCCGGCAGCCGGTCTTGGGACTCGCTTTCTGCCGGCAACAAAGTCAATGCCAAAAGAAATGCTTCCTA
TAATTGACACACCTGTAATTCAGTATGTAGTGGAGGAAGCTATTGCCTCAGGCATAGAAGATATTATTATTATTACAGGC
AGGGGCAAGAGAGCAATTGAGGACTACTTCGATGATTCTCCGGAACTTGAGATGCATCTTGCTAAAAAACACCAGACAGA
TATGCTGAAACTGGTCCGGGACATCTCTTCTCTTGTAGATATCCACTACATCCGCCAGAAAGAGCCCAATGGGCTTGGAG
ATGCGGTATTAAGGGCAGAAAACCATATCGGAGACGAGCCTTTTGCGGTGCTTCTCGGAGACGATATTATCGTTAACGAC
AAACCCTGCACTGCCCAGCTTATTGAGAACTTTGAGAAATACGGGAGGTCAACAATCGCAGTTGAAGAGGTCCCTTACGA
AAAACTGAGCAGTTATGGAATTATAAAAGGCAAGCCCCTCGATGATTCCCTTTATGTTCTTGAAGACATTGTAGAAAAAC
CAGCACCTGAAGATGCTCCTTCCAATATAGGAGCAATAGGGCGCTATGTATTCACGCCTGAGATTTTTGACTGCATAAAG
CATGCCGGTACTGGCGTTGGAAGTGAAATACAGCTCACAGACGGTATCAGGCTCCTTAACAAATCCCAGATGATCTATGC
CTGCAGATTTAAGGGAAAAAGGTTCGATACAGGAGACCGGCTCGGGTACGTAAAATCCATAGTCGATTTTGCTCTCCAGA
ACGAAAACCTCAGGGACGATGTGCTTGAATACCTTCGGGAAATTCTCGCAGTTAATAAGATTTCTCCAGAAATAGATAAG
TTAAAACAATAA

Upstream 100 bases:

>100_bases
CTTCTTTTTATTAATACTTTGCACTATTTTTTGCAAAAGCTGTAATTCTTTTTTCATACAATATGGGACTTTGCATAGAA
ATAGGGGAAAAATTAAAGTT

Downstream 100 bases:

>100_bases
TGCCGGAGAGACCTGAAAAATCAGGATATAATAAGCATCAGACAAAGGATACTTAAAAATAAATAAAAACAATAAATCTA
TGATATTGGTATATGGAAAG

Product: UTP--glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MGEKYFNSEEYNLTEFLFIGELTLTIKKALIPAAGLGTRFLPATKSMPKEMLPIIDTPVIQYVVEEAIASGIEDIIIITG
RGKRAIEDYFDDSPELEMHLAKKHQTDMLKLVRDISSLVDIHYIRQKEPNGLGDAVLRAENHIGDEPFAVLLGDDIIVND
KPCTAQLIENFEKYGRSTIAVEEVPYEKLSSYGIIKGKPLDDSLYVLEDIVEKPAPEDAPSNIGAIGRYVFTPEIFDCIK
HAGTGVGSEIQLTDGIRLLNKSQMIYACRFKGKRFDTGDRLGYVKSIVDFALQNENLRDDVLEYLREILAVNKISPEIDK
LKQ

Sequences:

>Translated_323_residues
MGEKYFNSEEYNLTEFLFIGELTLTIKKALIPAAGLGTRFLPATKSMPKEMLPIIDTPVIQYVVEEAIASGIEDIIIITG
RGKRAIEDYFDDSPELEMHLAKKHQTDMLKLVRDISSLVDIHYIRQKEPNGLGDAVLRAENHIGDEPFAVLLGDDIIVND
KPCTAQLIENFEKYGRSTIAVEEVPYEKLSSYGIIKGKPLDDSLYVLEDIVEKPAPEDAPSNIGAIGRYVFTPEIFDCIK
HAGTGVGSEIQLTDGIRLLNKSQMIYACRFKGKRFDTGDRLGYVKSIVDFALQNENLRDDVLEYLREILAVNKISPEIDK
LKQ
>Mature_322_residues
GEKYFNSEEYNLTEFLFIGELTLTIKKALIPAAGLGTRFLPATKSMPKEMLPIIDTPVIQYVVEEAIASGIEDIIIITGR
GKRAIEDYFDDSPELEMHLAKKHQTDMLKLVRDISSLVDIHYIRQKEPNGLGDAVLRAENHIGDEPFAVLLGDDIIVNDK
PCTAQLIENFEKYGRSTIAVEEVPYEKLSSYGIIKGKPLDDSLYVLEDIVEKPAPEDAPSNIGAIGRYVFTPEIFDCIKH
AGTGVGSEIQLTDGIRLLNKSQMIYACRFKGKRFDTGDRLGYVKSIVDFALQNENLRDDVLEYLREILAVNKISPEIDKL
KQ

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=304, Percent_Identity=40.1315789473684, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1788355, Length=282, Percent_Identity=40.0709219858156, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1788351, Length=258, Percent_Identity=25.968992248062, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790224, Length=230, Percent_Identity=25.2173913043478, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 36228; Mature: 36097

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEKYFNSEEYNLTEFLFIGELTLTIKKALIPAAGLGTRFLPATKSMPKEMLPIIDTPVI
CCCCCCCCCCCCHHHEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCHHHH
QYVVEEAIASGIEDIIIITGRGKRAIEDYFDDSPELEMHLAKKHQTDMLKLVRDISSLVD
HHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IHYIRQKEPNGLGDAVLRAENHIGDEPFAVLLGDDIIVNDKPCTAQLIENFEKYGRSTIA
HHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECCEEEECCCCCHHHHHHHHHHHCCCEEE
VEEVPYEKLSSYGIIKGKPLDDSLYVLEDIVEKPAPEDAPSNIGAIGRYVFTPEIFDCIK
EHHCCHHHHHCCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHEECHHHHHHHH
HAGTGVGSEIQLTDGIRLLNKSQMIYACRFKGKRFDTGDRLGYVKSIVDFALQNENLRDD
HHCCCCCCEEEECCCHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHH
VLEYLREILAVNKISPEIDKLKQ
HHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure 
GEKYFNSEEYNLTEFLFIGELTLTIKKALIPAAGLGTRFLPATKSMPKEMLPIIDTPVI
CCCCCCCCCCCHHHEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCHHHH
QYVVEEAIASGIEDIIIITGRGKRAIEDYFDDSPELEMHLAKKHQTDMLKLVRDISSLVD
HHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IHYIRQKEPNGLGDAVLRAENHIGDEPFAVLLGDDIIVNDKPCTAQLIENFEKYGRSTIA
HHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECCEEEECCCCCHHHHHHHHHHHCCCEEE
VEEVPYEKLSSYGIIKGKPLDDSLYVLEDIVEKPAPEDAPSNIGAIGRYVFTPEIFDCIK
EHHCCHHHHHCCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHEECHHHHHHHH
HAGTGVGSEIQLTDGIRLLNKSQMIYACRFKGKRFDTGDRLGYVKSIVDFALQNENLRDD
HHCCCCCCEEEECCCHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHH
VLEYLREILAVNKISPEIDKLKQ
HHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]