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The map label for this gene is yrbE [H]

Identifier: 21227224

GI number: 21227224

Start: 1323227

End: 1324177

Strand: Direct

Name: yrbE [H]

Synonym: MM_1122

Alternate gene names: 21227224

Gene position: 1323227-1324177 (Clockwise)

Preceding gene: 21227222

Following gene: 21227225

Centisome position: 32.3

GC content: 43.01

Gene sequence:

>951_bases
GTGGGGGAAAAAGAATTGATACGTGTAGGAGTGGTTGGAACCGGCTATATGGGAGAAAACCATGTCAGAATATATAGCGA
AATGGAAGATGTAAGACTGATAGGTATATCCGATCCCAATTCTTCAAGGGTAAAAGAGCTTGCGGCAAGATATGAAACAT
TGCCTTTTTCTGATCACAAAAAGATGTTCGGGAAAACAAATCTTGACGCGATAAGTATTGCAGCTCCTACTACCCTTCAC
TGTCCTATAGTGCTTGACGCCCTCGAAGCGGGAGTTGATGTGCTTGTAGAAAAGCCTATTGCAGACAGCGTGGAAAATGC
AACTGCAATGATCGAATCCGCTGAAGAGATGGACAGGCATCTGATGGTAGGCCATATAGAAAGATTTAACCCTGCAGTCC
TGAAATTAAAAGAGGTAGTTGACTCAGGAGTCCTGGGGAAAATAGTCTCAGTTTCGACAAGAAGAGTCGGTCCCTATAAC
CCAAGGATAAGAGATGTTGGTGTAATTCTGGATATAGGAGTCCATGATATAGATATAATCTCTTTTATTTACGGGATGAA
GATAAACCAGGTTTATGCCATAGCTGGCTCGGATATCCACTCTTTTGAGGATCATGCAACTATTCATCTGCGCCTTAACC
ATTCGTACTCAGGACTTGTAGAAACTAACTGGCTTACTCCGCATAAAATTAGGAAGCTTACAGCCGTTGGCGTGAAAGGA
GTTGCATATCTTGATTATCTCGACCAGAGTGTTGAGTTTCATGACAATGGCTGGGTACAGACAGCCAGGATAGAAAAAGC
TGAGCCTCTGCAAAAAGAGCTTTCCCATTTTATCTGCTGTTCCAGAGACGGAACCTGTCCGAGTCCTTCAGGGGAAGAAG
GAAAACATGCTCTTGAAGTGGCTTTAGCTGCAATTCAATCATACAGGGAAGAAAAAATGATAGAGATCTGA

Upstream 100 bases:

>100_bases
ATTTAAAGGATGAATTTTAAATTTACTGATAACATATTATTTGTGTTAAAATAGTGTGCTTTTCAGAAAAGGAAGAAAAA
GCACATGATGGATATTTATT

Downstream 100 bases:

>100_bases
AACTGCAGCCAGATGAAGCAACCTCCATACATTTGCCCGTTAACCTGCCTTTATTTACGGATTGAAAAATATTACGCAAA
ATAAACACTACGGAAAGAAC

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MGEKELIRVGVVGTGYMGENHVRIYSEMEDVRLIGISDPNSSRVKELAARYETLPFSDHKKMFGKTNLDAISIAAPTTLH
CPIVLDALEAGVDVLVEKPIADSVENATAMIESAEEMDRHLMVGHIERFNPAVLKLKEVVDSGVLGKIVSVSTRRVGPYN
PRIRDVGVILDIGVHDIDIISFIYGMKINQVYAIAGSDIHSFEDHATIHLRLNHSYSGLVETNWLTPHKIRKLTAVGVKG
VAYLDYLDQSVEFHDNGWVQTARIEKAEPLQKELSHFICCSRDGTCPSPSGEEGKHALEVALAAIQSYREEKMIEI

Sequences:

>Translated_316_residues
MGEKELIRVGVVGTGYMGENHVRIYSEMEDVRLIGISDPNSSRVKELAARYETLPFSDHKKMFGKTNLDAISIAAPTTLH
CPIVLDALEAGVDVLVEKPIADSVENATAMIESAEEMDRHLMVGHIERFNPAVLKLKEVVDSGVLGKIVSVSTRRVGPYN
PRIRDVGVILDIGVHDIDIISFIYGMKINQVYAIAGSDIHSFEDHATIHLRLNHSYSGLVETNWLTPHKIRKLTAVGVKG
VAYLDYLDQSVEFHDNGWVQTARIEKAEPLQKELSHFICCSRDGTCPSPSGEEGKHALEVALAAIQSYREEKMIEI
>Mature_315_residues
GEKELIRVGVVGTGYMGENHVRIYSEMEDVRLIGISDPNSSRVKELAARYETLPFSDHKKMFGKTNLDAISIAAPTTLHC
PIVLDALEAGVDVLVEKPIADSVENATAMIESAEEMDRHLMVGHIERFNPAVLKLKEVVDSGVLGKIVSVSTRRVGPYNP
RIRDVGVILDIGVHDIDIISFIYGMKINQVYAIAGSDIHSFEDHATIHLRLNHSYSGLVETNWLTPHKIRKLTAVGVKGV
AYLDYLDQSVEFHDNGWVQTARIEKAEPLQKELSHFICCSRDGTCPSPSGEEGKHALEVALAAIQSYREEKMIEI

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=212, Percent_Identity=28.7735849056604, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082405, Length=204, Percent_Identity=27.4509803921569, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87081947, Length=200, Percent_Identity=28.5, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787307, Length=184, Percent_Identity=25.5434782608696, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35013; Mature: 34881

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEKELIRVGVVGTGYMGENHVRIYSEMEDVRLIGISDPNSSRVKELAARYETLPFSDHK
CCCCCEEEEEEEEECCCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCHH
KMFGKTNLDAISIAAPTTLHCPIVLDALEAGVDVLVEKPIADSVENATAMIESAEEMDRH
HHCCCCCCCEEEECCCCEEECHHHHHHHHCCHHEEECCCCHHHHHHHHHHHHHHHHHHHH
LMVGHIERFNPAVLKLKEVVDSGVLGKIVSVSTRRVGPYNPRIRDVGVILDIGVHDIDII
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCHHHHH
SFIYGMKINQVYAIAGSDIHSFEDHATIHLRLNHSYSGLVETNWLTPHKIRKLTAVGVKG
HHHHCCEECEEEEEECCCCCCCCCCEEEEEEEECCCCCEEEECCCCHHHHHHHHHHCCCH
VAYLDYLDQSVEFHDNGWVQTARIEKAEPLQKELSHFICCSRDGTCPSPSGEEGKHALEV
HHHHHHHCCCCEECCCCCEEEEECCCCCHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHH
ALAAIQSYREEKMIEI
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GEKELIRVGVVGTGYMGENHVRIYSEMEDVRLIGISDPNSSRVKELAARYETLPFSDHK
CCCCEEEEEEEEECCCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCHH
KMFGKTNLDAISIAAPTTLHCPIVLDALEAGVDVLVEKPIADSVENATAMIESAEEMDRH
HHCCCCCCCEEEECCCCEEECHHHHHHHHCCHHEEECCCCHHHHHHHHHHHHHHHHHHHH
LMVGHIERFNPAVLKLKEVVDSGVLGKIVSVSTRRVGPYNPRIRDVGVILDIGVHDIDII
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCHHHHH
SFIYGMKINQVYAIAGSDIHSFEDHATIHLRLNHSYSGLVETNWLTPHKIRKLTAVGVKG
HHHHCCEECEEEEEECCCCCCCCCCEEEEEEEECCCCCEEEECCCCHHHHHHHHHHCCCH
VAYLDYLDQSVEFHDNGWVQTARIEKAEPLQKELSHFICCSRDGTCPSPSGEEGKHALEV
HHHHHHHCCCCEECCCCCEEEEECCCCCHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHH
ALAAIQSYREEKMIEI
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]