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The map label for this gene is yegE [C]

Identifier: 21227195

GI number: 21227195

Start: 1285023

End: 1287518

Strand: Direct

Name: yegE [C]

Synonym: MM_1093

Alternate gene names: 21227195

Gene position: 1285023-1287518 (Clockwise)

Preceding gene: 21227194

Following gene: 21227196

Centisome position: 31.37

GC content: 41.87

Gene sequence:

>2496_bases
ATGCTAAAAATGCAATTTTTGGGGAAGGGCGTTGTAAATATGAGTTCAAAATTGGCGAAAGACCAGGGAAACGTGCCATA
TCAGAAGCTGTTAGATAAAAATCATGCCCTGGAAGCAGAGTTACAGGATCTAAAAATGCGGCTGGAAGAGGCTGAAGAAC
TCAGGCGTGCCATCAGTGAGGGGGATCTGGATGCTCTGATTATACCTGGACCTCAAGAAAAATTGATTTTCACCCTGGAT
AGTGCCGACCGTGCATATCGTGTTCTTGTGGAGGCAATGAATGAGGGTACTGCCACCCTTGCCTCCGACGGTACTATTCT
TTACTGCAATCGCCAATTTGCAGAACTCACAAAGATGTCATCCGGGGCTGTAGTAGGTACGTCTATTTATGGATTTATTG
CGCCAGAAGATGCTATTACCTTTAAGGCACTCCTGAAACAGAAAAACAGTGTAGGGGAGTTGAAATTTAGGGCTCAGGGT
GGTACGTCTGTACCAGTATACCTGTCTATCAGTTCATTGCAGTCCGAGGGATCACCAAGTGCATGGTGCCTTGTGGTTAC
AGACCTGACTGAGCAGAAGAAGAATGAAGAAATAGTTGCTGCTGAACGTCTGGCCCGGTCAATTATAGAACAGGCTGCCG
AAGCCATAGTAGTCTGCGACACGACTGGAAGGATCACATATTTCAGCAACACAGTGTCCAAGGTCTGTAAATGCGATCCG
GCGTTCAAGAGATTTGAAGATATCATAGATATCCGGTTCTCAGAAGGAAAAGATGCAGGAAAAAGTATTCTTCCGGTCTC
CTCTGCTCTGAAAGGAGATACCATCCTTGGATTGGAAGCAATCTTAGAATATAAAAGTTGCCAGAAGTTCAACCAGAAGC
TCCATTTACTATTAAATTCAGGACCTCTCAGAAACTCCAATGGCAGGATAATAGGCTGTGTAGTAACTCTCACGGATATC
ACTGAGCGCAAGAAAATGGAAAGGGAGCTTCAAGAGAGTGAGGAAAAATACCGAAATATCGTAGAGACAGCAAACGAAGG
TATATGGATACTTGACCCTGAAGCCAGAATTACTTATGTTAATCAGAGAATGGCAGAGATGCTGGGATACAATCATGAAG
AAATAATTGGAAGGTCTGCATGGGACTTTACCGGTGATGAAGGAAAAGAAGCTGCCAAGCAGAGTATGGAAAAAGGAAAG
CAGCGTATTGATAGAGATCATGAATTAAAATTAATAAGCAAAAATGGTACGCCTCTATGGACAATTGTAAGTGCTAAAGC
TCTTTTTGATAAAGATGGCAATTTTATGGGCTCTATGAAGATGCTTACAAACATTACCGAAAGAAAAGAAGCAGAAGTTA
AACTAAAACAAACCCTCAACAATTTGGAAAAATTAGTTCAGGAACGCACGATAGAGCTTGAGAAGGCTTACGGCTCATTA
AAAGAAAGCGAAAGAGGTCTTGCTGAGGCTCAAAAAATGGCACACATCGGAAACTGGGATCGGAGTCTTATAACTAATGA
AGTTCACTGGTCTGATGAAGTTTATCGTATTTTTGGATTTAAGCCTAAGGAATTTGGAGTAACTTATAGCACATATTTAA
ATTGTGTACATCCTGACGACCAAGACCGAGTAATTAAGGCAGCTAAACAGGCTTTAGAGGGAAAACTCTCCAGTATTGAT
TACAGGATTGTCCTGAACAATGGGGAGGAGCGTGTAGTCCATGAGGAATTCAAAGTTGTCTTTGATGAGAAAAGTAATCC
TGTCCAACTCAGAGGAACAGTTCAGGATATTACGGAGCGTAAAAAAGCTGAAGAAACCCTGGAAAAAATGGACAAAATCC
GCATAAAAGAAATCCACCACAGAATCAAAAATAACCTGCAGGTTATATGTTCTCTTCTCAGTCTTGAAGCTGAAAGATTC
AGTGACGAAAAGATGCTTGAAACTTTGAAAGAGAGCCAGAACCGTGTAGCTTCAATGGCTCTGATACACGAAGAGCTCTA
CAAAGGAGATAAAAACGACACCCTTGACTTTGCAGCTTATCTCCGCAAACTCACTGCTGATCTATTCAGCTCATATAATC
TAGGAAATGACAATATCAGCTTGAAAATGGATCTTGAGCAGGTATATCTGGATATGGATACAGCAATCCCTCTTGGTATC
ATTGTAAATGAACTGTTTTCAAACTCCCTGAAGCATGCTTTCCCTGCTGGAAGCGAAGGCGAAGTCCATATAAGCCTGAG
AAGAGCTGAGACTTTTGACAAAGGAAACAATGTATCAGACTCGGACCAGCACTGCAACGAAATAGATAATTTCCGATACA
TACTCAGAGTGGCTGACAATGGAAAGGGCATATCAAAAGAAATAGAGATCGAAAATGCTGATTCTCTAGGGCTCCAGCTT
GTAAATATCCTTGTTGACCAAATAGACGGCTGTGTAGAGCTCAGTAGAAATTGCGGGACAGAATTTACAATCTGGTTTGG
GGATAAAGAGCCGTAA

Upstream 100 bases:

>100_bases
TAAAAGAGCTCCCTCCACCATTAAGAAAGCTCATAGGCAGCATGTCAGATACCGAAAGGGTCCTTATGGGGATGGACCTG
AAATCAAAAAAAGATAAAGA

Downstream 100 bases:

>100_bases
GCTCTTCAATTTATGGCTGTCTATTCAAAACCCGTTTTCACTTAAATATCCACAAAAGTTCCATAACTACTTTTCCGATC
AGTAGCTCGATTTATTACTT

Product: sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 831; Mature: 831

Protein sequence:

>831_residues
MLKMQFLGKGVVNMSSKLAKDQGNVPYQKLLDKNHALEAELQDLKMRLEEAEELRRAISEGDLDALIIPGPQEKLIFTLD
SADRAYRVLVEAMNEGTATLASDGTILYCNRQFAELTKMSSGAVVGTSIYGFIAPEDAITFKALLKQKNSVGELKFRAQG
GTSVPVYLSISSLQSEGSPSAWCLVVTDLTEQKKNEEIVAAERLARSIIEQAAEAIVVCDTTGRITYFSNTVSKVCKCDP
AFKRFEDIIDIRFSEGKDAGKSILPVSSALKGDTILGLEAILEYKSCQKFNQKLHLLLNSGPLRNSNGRIIGCVVTLTDI
TERKKMERELQESEEKYRNIVETANEGIWILDPEARITYVNQRMAEMLGYNHEEIIGRSAWDFTGDEGKEAAKQSMEKGK
QRIDRDHELKLISKNGTPLWTIVSAKALFDKDGNFMGSMKMLTNITERKEAEVKLKQTLNNLEKLVQERTIELEKAYGSL
KESERGLAEAQKMAHIGNWDRSLITNEVHWSDEVYRIFGFKPKEFGVTYSTYLNCVHPDDQDRVIKAAKQALEGKLSSID
YRIVLNNGEERVVHEEFKVVFDEKSNPVQLRGTVQDITERKKAEETLEKMDKIRIKEIHHRIKNNLQVICSLLSLEAERF
SDEKMLETLKESQNRVASMALIHEELYKGDKNDTLDFAAYLRKLTADLFSSYNLGNDNISLKMDLEQVYLDMDTAIPLGI
IVNELFSNSLKHAFPAGSEGEVHISLRRAETFDKGNNVSDSDQHCNEIDNFRYILRVADNGKGISKEIEIENADSLGLQL
VNILVDQIDGCVELSRNCGTEFTIWFGDKEP

Sequences:

>Translated_831_residues
MLKMQFLGKGVVNMSSKLAKDQGNVPYQKLLDKNHALEAELQDLKMRLEEAEELRRAISEGDLDALIIPGPQEKLIFTLD
SADRAYRVLVEAMNEGTATLASDGTILYCNRQFAELTKMSSGAVVGTSIYGFIAPEDAITFKALLKQKNSVGELKFRAQG
GTSVPVYLSISSLQSEGSPSAWCLVVTDLTEQKKNEEIVAAERLARSIIEQAAEAIVVCDTTGRITYFSNTVSKVCKCDP
AFKRFEDIIDIRFSEGKDAGKSILPVSSALKGDTILGLEAILEYKSCQKFNQKLHLLLNSGPLRNSNGRIIGCVVTLTDI
TERKKMERELQESEEKYRNIVETANEGIWILDPEARITYVNQRMAEMLGYNHEEIIGRSAWDFTGDEGKEAAKQSMEKGK
QRIDRDHELKLISKNGTPLWTIVSAKALFDKDGNFMGSMKMLTNITERKEAEVKLKQTLNNLEKLVQERTIELEKAYGSL
KESERGLAEAQKMAHIGNWDRSLITNEVHWSDEVYRIFGFKPKEFGVTYSTYLNCVHPDDQDRVIKAAKQALEGKLSSID
YRIVLNNGEERVVHEEFKVVFDEKSNPVQLRGTVQDITERKKAEETLEKMDKIRIKEIHHRIKNNLQVICSLLSLEAERF
SDEKMLETLKESQNRVASMALIHEELYKGDKNDTLDFAAYLRKLTADLFSSYNLGNDNISLKMDLEQVYLDMDTAIPLGI
IVNELFSNSLKHAFPAGSEGEVHISLRRAETFDKGNNVSDSDQHCNEIDNFRYILRVADNGKGISKEIEIENADSLGLQL
VNILVDQIDGCVELSRNCGTEFTIWFGDKEP
>Mature_831_residues
MLKMQFLGKGVVNMSSKLAKDQGNVPYQKLLDKNHALEAELQDLKMRLEEAEELRRAISEGDLDALIIPGPQEKLIFTLD
SADRAYRVLVEAMNEGTATLASDGTILYCNRQFAELTKMSSGAVVGTSIYGFIAPEDAITFKALLKQKNSVGELKFRAQG
GTSVPVYLSISSLQSEGSPSAWCLVVTDLTEQKKNEEIVAAERLARSIIEQAAEAIVVCDTTGRITYFSNTVSKVCKCDP
AFKRFEDIIDIRFSEGKDAGKSILPVSSALKGDTILGLEAILEYKSCQKFNQKLHLLLNSGPLRNSNGRIIGCVVTLTDI
TERKKMERELQESEEKYRNIVETANEGIWILDPEARITYVNQRMAEMLGYNHEEIIGRSAWDFTGDEGKEAAKQSMEKGK
QRIDRDHELKLISKNGTPLWTIVSAKALFDKDGNFMGSMKMLTNITERKEAEVKLKQTLNNLEKLVQERTIELEKAYGSL
KESERGLAEAQKMAHIGNWDRSLITNEVHWSDEVYRIFGFKPKEFGVTYSTYLNCVHPDDQDRVIKAAKQALEGKLSSID
YRIVLNNGEERVVHEEFKVVFDEKSNPVQLRGTVQDITERKKAEETLEKMDKIRIKEIHHRIKNNLQVICSLLSLEAERF
SDEKMLETLKESQNRVASMALIHEELYKGDKNDTLDFAAYLRKLTADLFSSYNLGNDNISLKMDLEQVYLDMDTAIPLGI
IVNELFSNSLKHAFPAGSEGEVHISLRRAETFDKGNNVSDSDQHCNEIDNFRYILRVADNGKGISKEIEIENADSLGLQL
VNILVDQIDGCVELSRNCGTEFTIWFGDKEP

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light. Once ejected from an infected animal host, sunlight acts as an environmental signal that increases the virulence of the bacterium, preparing it for infection o

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=283, Percent_Identity=21.9081272084806, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR011102 [H]

Pfam domain/function: PF07536 HWE_HK; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 93643; Mature: 93643

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKMQFLGKGVVNMSSKLAKDQGNVPYQKLLDKNHALEAELQDLKMRLEEAEELRRAISE
CCCHHHHCCCHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
GDLDALIIPGPQEKLIFTLDSADRAYRVLVEAMNEGTATLASDGTILYCNRQFAELTKMS
CCCCEEEECCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCEEEEECCHHHHHHHCC
SGAVVGTSIYGFIAPEDAITFKALLKQKNSVGELKFRAQGGTSVPVYLSISSLQSEGSPS
CCCEEEEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEHHCCCCCCC
AWCLVVTDLTEQKKNEEIVAAERLARSIIEQAAEAIVVCDTTGRITYFSNTVSKVCKCDP
EEEEEEECCHHCCCCCHHHHHHHHHHHHHHHHHCEEEEECCCCCEEEEHHHHHHHHCCCH
AFKRFEDIIDIRFSEGKDAGKSILPVSSALKGDTILGLEAILEYKSCQKFNQKLHLLLNS
HHHHHHHHHHEEECCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEECC
GPLRNSNGRIIGCVVTLTDITERKKMERELQESEEKYRNIVETANEGIWILDPEARITYV
CCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEHH
NQRMAEMLGYNHEEIIGRSAWDFTGDEGKEAAKQSMEKGKQRIDRDHELKLISKNGTPLW
HHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEE
TIVSAKALFDKDGNFMGSMKMLTNITERKEAEVKLKQTLNNLEKLVQERTIELEKAYGSL
EEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KESERGLAEAQKMAHIGNWDRSLITNEVHWSDEVYRIFGFKPKEFGVTYSTYLNCVHPDD
HHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCEEEECCCCHHHCCCHHHHEEECCCCC
QDRVIKAAKQALEGKLSSIDYRIVLNNGEERVVHEEFKVVFDEKSNPVQLRGTVQDITER
HHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHEECCCCCCEEEEEHHHHHHHH
KKAEETLEKMDKIRIKEIHHRIKNNLQVICSLLSLEAERFSDEKMLETLKESQNRVASMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LIHEELYKGDKNDTLDFAAYLRKLTADLFSSYNLGNDNISLKMDLEQVYLDMDTAIPLGI
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHCCCCHHHH
IVNELFSNSLKHAFPAGSEGEVHISLRRAETFDKGNNVSDSDQHCNEIDNFRYILRVADN
HHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHCEEEEEEEECC
GKGISKEIEIENADSLGLQLVNILVDQIDGCVELSRNCGTEFTIWFGDKEP
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
>Mature Secondary Structure
MLKMQFLGKGVVNMSSKLAKDQGNVPYQKLLDKNHALEAELQDLKMRLEEAEELRRAISE
CCCHHHHCCCHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
GDLDALIIPGPQEKLIFTLDSADRAYRVLVEAMNEGTATLASDGTILYCNRQFAELTKMS
CCCCEEEECCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCEEEEECCHHHHHHHCC
SGAVVGTSIYGFIAPEDAITFKALLKQKNSVGELKFRAQGGTSVPVYLSISSLQSEGSPS
CCCEEEEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEHHCCCCCCC
AWCLVVTDLTEQKKNEEIVAAERLARSIIEQAAEAIVVCDTTGRITYFSNTVSKVCKCDP
EEEEEEECCHHCCCCCHHHHHHHHHHHHHHHHHCEEEEECCCCCEEEEHHHHHHHHCCCH
AFKRFEDIIDIRFSEGKDAGKSILPVSSALKGDTILGLEAILEYKSCQKFNQKLHLLLNS
HHHHHHHHHHEEECCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEECC
GPLRNSNGRIIGCVVTLTDITERKKMERELQESEEKYRNIVETANEGIWILDPEARITYV
CCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEHH
NQRMAEMLGYNHEEIIGRSAWDFTGDEGKEAAKQSMEKGKQRIDRDHELKLISKNGTPLW
HHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEE
TIVSAKALFDKDGNFMGSMKMLTNITERKEAEVKLKQTLNNLEKLVQERTIELEKAYGSL
EEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KESERGLAEAQKMAHIGNWDRSLITNEVHWSDEVYRIFGFKPKEFGVTYSTYLNCVHPDD
HHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCEEEECCCCHHHCCCHHHHEEECCCCC
QDRVIKAAKQALEGKLSSIDYRIVLNNGEERVVHEEFKVVFDEKSNPVQLRGTVQDITER
HHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHEECCCCCCEEEEEHHHHHHHH
KKAEETLEKMDKIRIKEIHHRIKNNLQVICSLLSLEAERFSDEKMLETLKESQNRVASMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LIHEELYKGDKNDTLDFAAYLRKLTADLFSSYNLGNDNISLKMDLEQVYLDMDTAIPLGI
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHCCCCHHHH
IVNELFSNSLKHAFPAGSEGEVHISLRRAETFDKGNNVSDSDQHCNEIDNFRYILRVADN
HHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHCEEEEEEEECC
GKGISKEIEIENADSLGLQLVNILVDQIDGCVELSRNCGTEFTIWFGDKEP
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA