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The map label for this gene is cbiC [H]

Identifier: 21227096

GI number: 21227096

Start: 1170174

End: 1170905

Strand: Reverse

Name: cbiC [H]

Synonym: MM_0994

Alternate gene names: 21227096

Gene position: 1170905-1170174 (Counterclockwise)

Preceding gene: 21227097

Following gene: 21227095

Centisome position: 28.58

GC content: 47.81

Gene sequence:

>732_bases
ATGACTACTGAACAAAAAGCCAATGAAAATGCAGGAAACCTTGAAAACCTCGAAGAATTTACCGAGCTTACAGTGGAAGT
AGACCCCGAACTTGTAAAGATCTGCAATGACTCCGGGGCAAGGACTGATGAGGCAAAAGCCATCTACATGAAAAGCCGGA
CAATGATCCGTGAGATTGTCGGTAACTCCACTCCCGAAGACCGCTTCCGGCAGCGCTGTGTTATTGCAACAGGAGACCTT
TCTGTCGCCGATATCATGCGTTTCAATAACGACCCCATACCTACAGGTGTTGAGGCAATTAAAAAAGGTGCCCCCATTTT
TGTGGACATCAATATGGTAAAATCCGGGATCACAAAAGCCGGGCATAAATCCGAAATCATCTGCGTGCTTGACGAAGACC
CCGACGCTAAAATCGCCAACAAGTACGGGATAACCAGGACATCGGCAGGTTTCCTGGCGGCAAGGGAAAAACTCGATGGA
AGCATTATAGCTATTGGAAATGCTCCTTCTGCCCTTATTATGGTCTGCAAGCTTATTGAGAAAGGTGTAAGGCCTGCCCT
TATTATCGGTCTTCCTGTCGGTTTTGTCAATGCAGCCGAATCAAGGGAAATGGTTAGAAACCTGAAAATCCCGATTCCTT
CTATCAGCTGTGTCGGGACCAGGGGAGGGACTCCGATGGCTGTTGCCTGCGTAAACGAGCTCGTAGCAATCGCAAGAGAA
AGTGAGGAGTAA

Upstream 100 bases:

>100_bases
GACATGAGCACTGCTATTCTCATAGGCAACGGAGAGTCCAGGATCTGGAAGTCTCCGAAAAAGGATATAATAATAACTCC
CAGGGGGTATCATAAGAAAT

Downstream 100 bases:

>100_bases
TCTCCCTGCTTTCTTTTTTAATTTTATTTTTTTCTCTGTTTTTTGTTCTGTCATCGGCTTATTAGTAGCCATCTGCATGA
TATTATTTCTCTTTTTTTTC

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MTTEQKANENAGNLENLEEFTELTVEVDPELVKICNDSGARTDEAKAIYMKSRTMIREIVGNSTPEDRFRQRCVIATGDL
SVADIMRFNNDPIPTGVEAIKKGAPIFVDINMVKSGITKAGHKSEIICVLDEDPDAKIANKYGITRTSAGFLAAREKLDG
SIIAIGNAPSALIMVCKLIEKGVRPALIIGLPVGFVNAAESREMVRNLKIPIPSISCVGTRGGTPMAVACVNELVAIARE
SEE

Sequences:

>Translated_243_residues
MTTEQKANENAGNLENLEEFTELTVEVDPELVKICNDSGARTDEAKAIYMKSRTMIREIVGNSTPEDRFRQRCVIATGDL
SVADIMRFNNDPIPTGVEAIKKGAPIFVDINMVKSGITKAGHKSEIICVLDEDPDAKIANKYGITRTSAGFLAAREKLDG
SIIAIGNAPSALIMVCKLIEKGVRPALIIGLPVGFVNAAESREMVRNLKIPIPSISCVGTRGGTPMAVACVNELVAIARE
SEE
>Mature_242_residues
TTEQKANENAGNLENLEEFTELTVEVDPELVKICNDSGARTDEAKAIYMKSRTMIREIVGNSTPEDRFRQRCVIATGDLS
VADIMRFNNDPIPTGVEAIKKGAPIFVDINMVKSGITKAGHKSEIICVLDEDPDAKIANKYGITRTSAGFLAAREKLDGS
IIAIGNAPSALIMVCKLIEKGVRPALIIGLPVGFVNAAESREMVRNLKIPIPSISCVGTRGGTPMAVACVNELVAIARES
EE

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 26145; Mature: 26013

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEQKANENAGNLENLEEFTELTVEVDPELVKICNDSGARTDEAKAIYMKSRTMIREIV
CCCCCCCCCCCCCHHHHHHHHHEEEEECHHHHHHHCCCCCCCCCHHEEHHHHHHHHHHHH
GNSTPEDRFRQRCVIATGDLSVADIMRFNNDPIPTGVEAIKKGAPIFVDINMVKSGITKA
CCCCCHHHHHCEEEEEECCCCHHHHHHHCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHCC
GHKSEIICVLDEDPDAKIANKYGITRTSAGFLAAREKLDGSIIAIGNAPSALIMVCKLIE
CCCCCEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHH
KGVRPALIIGLPVGFVNAAESREMVRNLKIPIPSISCVGTRGGTPMAVACVNELVAIARE
HCCCCEEEEECCCHHHCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHC
SEE
CCC
>Mature Secondary Structure 
TTEQKANENAGNLENLEEFTELTVEVDPELVKICNDSGARTDEAKAIYMKSRTMIREIV
CCCCCCCCCCCCHHHHHHHHHEEEEECHHHHHHHCCCCCCCCCHHEEHHHHHHHHHHHH
GNSTPEDRFRQRCVIATGDLSVADIMRFNNDPIPTGVEAIKKGAPIFVDINMVKSGITKA
CCCCCHHHHHCEEEEEECCCCHHHHHHHCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHCC
GHKSEIICVLDEDPDAKIANKYGITRTSAGFLAAREKLDGSIIAIGNAPSALIMVCKLIE
CCCCCEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHH
KGVRPALIIGLPVGFVNAAESREMVRNLKIPIPSISCVGTRGGTPMAVACVNELVAIARE
HCCCCEEEEECCCHHHCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHC
SEE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]