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The map label for this gene is fno [H]

Identifier: 21227079

GI number: 21227079

Start: 1158274

End: 1158981

Strand: Direct

Name: fno [H]

Synonym: MM_0977

Alternate gene names: 21227079

Gene position: 1158274-1158981 (Clockwise)

Preceding gene: 21227077

Following gene: 21227080

Centisome position: 28.28

GC content: 44.77

Gene sequence:

>708_bases
TTGAATTCTGAAAAGCTAAAAATAGCTGTTCTAGGAGGAACCGGCAATATAGGAGAAGGAATGGTACTGAGACTTGCCCT
TCAAAACCTTATGCCTGAAGGTGTGAAGAATGAGATAATTATTGGATCCAGATCTCTGGAAACTGCAGAAGAAGCTGCAA
AAAAAGCGTTATCAGAACTTGAGAACTGCGGGTTCGATACGTCCGGCATAAAGATTACCGGAATGAATAACTTTGAAGCT
GCAAAAGCAGCCGAAATGGCAATACTCACGATCCGTTTTGACCATGTTCTTCCTCTTCTGGAAGAAATAAAAGAGACACT
TGAGAATAAAATAGTTATTTCTCCGGTAGTCCCAATGGTGAAAGAAGGTAGCTTTATGGCGTACAGGCCTCCTGCAGAGG
GTTCGGCAGCTCTTGCAATCCAGAAAAATGTCCCGGAGACCACGAAAGTTGTTGCAGCCTTCCATAATATTCCTGCAGGA
AAACTCAAGGATGTTGTTAAATGCAAAGCAGTGCACGACGCACTTGTTTGCAGCGATGACGAAGAGGCAAAGAAACTGGT
CATGGAGCTTACACGGCATATGGGATGCCTCAAACCCCTTGATGGAGGCCCCCTTAAGCAGGCAGCTACCATGGAATCCC
TGACCCCGCTACTTATAAATCTGGCGAAATTGAACGGGCTTAAAGACCTCGGAATAAATTTCTCCTGA

Upstream 100 bases:

>100_bases
ATAACATTAAGTATTATAATCATATGATTTAAGACAGAAGATATATTAACTTCCTGACATATGTTATGGGAAGACATAGC
AAACTGGAGGTCCTGTTCAA

Downstream 100 bases:

>100_bases
ACAATCCAGGCAAAAATGTCAGGGAAAACGTATATAAGGAATGAAGTTTGCCGAAAAAGGAATTAAAGGGTGAAGGGCTT
ACTCAAAAAATTTCTCTTAT

Product: F420-dependent NADP reductase

Products: NA

Alternate protein names: F420H2:NADP oxidoreductase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MNSEKLKIAVLGGTGNIGEGMVLRLALQNLMPEGVKNEIIIGSRSLETAEEAAKKALSELENCGFDTSGIKITGMNNFEA
AKAAEMAILTIRFDHVLPLLEEIKETLENKIVISPVVPMVKEGSFMAYRPPAEGSAALAIQKNVPETTKVVAAFHNIPAG
KLKDVVKCKAVHDALVCSDDEEAKKLVMELTRHMGCLKPLDGGPLKQAATMESLTPLLINLAKLNGLKDLGINFS

Sequences:

>Translated_235_residues
MNSEKLKIAVLGGTGNIGEGMVLRLALQNLMPEGVKNEIIIGSRSLETAEEAAKKALSELENCGFDTSGIKITGMNNFEA
AKAAEMAILTIRFDHVLPLLEEIKETLENKIVISPVVPMVKEGSFMAYRPPAEGSAALAIQKNVPETTKVVAAFHNIPAG
KLKDVVKCKAVHDALVCSDDEEAKKLVMELTRHMGCLKPLDGGPLKQAATMESLTPLLINLAKLNGLKDLGINFS
>Mature_235_residues
MNSEKLKIAVLGGTGNIGEGMVLRLALQNLMPEGVKNEIIIGSRSLETAEEAAKKALSELENCGFDTSGIKITGMNNFEA
AKAAEMAILTIRFDHVLPLLEEIKETLENKIVISPVVPMVKEGSFMAYRPPAEGSAALAIQKNVPETTKVVAAFHNIPAG
KLKDVVKCKAVHDALVCSDDEEAKKLVMELTRHMGCLKPLDGGPLKQAATMESLTPLLINLAKLNGLKDLGINFS

Specific function: Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions [H]

COG id: COG2085

COG function: function code R; Predicted dinucleotide-binding enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the F420-dependent NADP reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR004455
- InterPro:   IPR010185 [H]

Pfam domain/function: PF03807 F420_oxidored [H]

EC number: NA

Molecular weight: Translated: 25188; Mature: 25188

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSEKLKIAVLGGTGNIGEGMVLRLALQNLMPEGVKNEIIIGSRSLETAEEAAKKALSEL
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHH
ENCGFDTSGIKITGMNNFEAAKAAEMAILTIRFDHVLPLLEEIKETLENKIVISPVVPMV
HHCCCCCCCEEEEECCCCCHHHHHHEEEEEEEHHHHHHHHHHHHHHHHCCEEEECCCHHH
KEGSFMAYRPPAEGSAALAIQKNVPETTKVVAAFHNIPAGKLKDVVKCKAVHDALVCSDD
HCCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
EEAKKLVMELTRHMGCLKPLDGGPLKQAATMESLTPLLINLAKLNGLKDLGINFS
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCC
>Mature Secondary Structure
MNSEKLKIAVLGGTGNIGEGMVLRLALQNLMPEGVKNEIIIGSRSLETAEEAAKKALSEL
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHH
ENCGFDTSGIKITGMNNFEAAKAAEMAILTIRFDHVLPLLEEIKETLENKIVISPVVPMV
HHCCCCCCCEEEEECCCCCHHHHHHEEEEEEEHHHHHHHHHHHHHHHHCCEEEECCCHHH
KEGSFMAYRPPAEGSAALAIQKNVPETTKVVAAFHNIPAGKLKDVVKCKAVHDALVCSDD
HCCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
EEAKKLVMELTRHMGCLKPLDGGPLKQAATMESLTPLLINLAKLNGLKDLGINFS
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]