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The map label for this gene is macB [H]

Identifier: 21227053

GI number: 21227053

Start: 1127890

End: 1129104

Strand: Reverse

Name: macB [H]

Synonym: MM_0951

Alternate gene names: 21227053

Gene position: 1129104-1127890 (Counterclockwise)

Preceding gene: 21227054

Following gene: 21227052

Centisome position: 27.56

GC content: 43.62

Gene sequence:

>1215_bases
ATGATACAATTTGTACAGGCGGCTCACATTGCTTCAGGAAGCATACGCAGCGCCAAGCTTCGGTCTGCACTCACGACACT
CGGAATAGTGATAGGCGTCGCAGCAGTAATTATAAACGCATCCCTAGGTGCCAGCTTTAATCAGTTCTTCACTGATGAAG
TTTCCTCAGTGGGCTCAAACTTTATAATTGCATATAGCGATCAGCCAAACCTCTTCTATGATAGTGAGCTTGAAATTATT
AAAAACACTCCCGGGATTTTAGGAGTTTCTCCCAGGAAGACGGTATCCGGAGAGATCAATTACCTTTCTGATGTTAAAAG
CGTGAGCATTGTGGGTGTAAACGGAGATTTTCAGGAAATCCAGGGAATCAAAATGGAAGAGGGCAGTTTCCTTACAGATA
AGGATATTTATTCTGCTGTGCTCGGGTATGATCTTGCGAAAGAGGAATTTGGCAGGAGTATTTCGCACAGGAGCAGTGTT
GATATTGCTTTCCGGCAGGAGGACGGCACGCTTGTAATAAAAAAATTCAAAGTAAAAGGGATTCTGGAGGATTCAAAAGA
AACTATTGTTGGAGGGGATGGCAGTACAGACATGATAGTCTATATCCCTATCTCGACCATGAATGAGATGACTGGGGAAA
AGGACTATGGAGCCTTTTTTGCGATGGCAGAAAGTTCTGAAAACATCGGCAGTATTTCGAAAGACGTGGATAAAAGACTT
GCCCGAAGCTTCGGAATTTCTGAAAGGGATCTCAACAATGAAGACGCGAAGCCTTATACTGTATTCGATCAGGCAGATGT
CCTAGAAGAGACCGGTGCACTGGGAAAAGCTTTGAGCACTTTTCTGCTTGTCCTTGCTTTAATTTCACTGTTTGTAGGCT
CAATAGGAATAATGAATATCATGCTTGTTACGGTCACTGAACGCACAAGGGAGATCGGTATTATGAAGTCCGTAGGTTAC
AGCAGTTCCAATATTTTGTCCCTTTTTTTACTGGAGTCAATAATGGTCAGCTCTCTCGGCGGGCTACTGGGTACTGCTAT
AGGAGGTTTTGGAGCCTATATCCTTGAAGAGGCACTTAAACTTCCGCCGGTTTTCCCTTTCAAGTTAATCGAAATCGGAA
TTCTTATTTCGGTTCTCGTGGGAGTGGGCGCGGGATTGTACCCTGCAAGAAAAGCTGCAAATATGAATCCTGTAGATGCC
TTACGATATGAATAA

Upstream 100 bases:

>100_bases
ATTGCAGTCATTTTTATCCCTGCAGCTGTTCTCCTGTATAGAAGAAAAAAATAATGAGTGAATGAAGGCCTTCTAAATGT
CATATTTGCGGGGGTAAAAT

Downstream 100 bases:

>100_bases
GGGTCTTTTAAGTTTGAAGGAATGACCCTTATTCTTTCAATATTTTTTACCATCTCTATCTTTTTCTTCGAGTTTTTTTC
TACTTTTAATCCCGTTATAT

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MIQFVQAAHIASGSIRSAKLRSALTTLGIVIGVAAVIINASLGASFNQFFTDEVSSVGSNFIIAYSDQPNLFYDSELEII
KNTPGILGVSPRKTVSGEINYLSDVKSVSIVGVNGDFQEIQGIKMEEGSFLTDKDIYSAVLGYDLAKEEFGRSISHRSSV
DIAFRQEDGTLVIKKFKVKGILEDSKETIVGGDGSTDMIVYIPISTMNEMTGEKDYGAFFAMAESSENIGSISKDVDKRL
ARSFGISERDLNNEDAKPYTVFDQADVLEETGALGKALSTFLLVLALISLFVGSIGIMNIMLVTVTERTREIGIMKSVGY
SSSNILSLFLLESIMVSSLGGLLGTAIGGFGAYILEEALKLPPVFPFKLIEIGILISVLVGVGAGLYPARKAANMNPVDA
LRYE

Sequences:

>Translated_404_residues
MIQFVQAAHIASGSIRSAKLRSALTTLGIVIGVAAVIINASLGASFNQFFTDEVSSVGSNFIIAYSDQPNLFYDSELEII
KNTPGILGVSPRKTVSGEINYLSDVKSVSIVGVNGDFQEIQGIKMEEGSFLTDKDIYSAVLGYDLAKEEFGRSISHRSSV
DIAFRQEDGTLVIKKFKVKGILEDSKETIVGGDGSTDMIVYIPISTMNEMTGEKDYGAFFAMAESSENIGSISKDVDKRL
ARSFGISERDLNNEDAKPYTVFDQADVLEETGALGKALSTFLLVLALISLFVGSIGIMNIMLVTVTERTREIGIMKSVGY
SSSNILSLFLLESIMVSSLGGLLGTAIGGFGAYILEEALKLPPVFPFKLIEIGILISVLVGVGAGLYPARKAANMNPVDA
LRYE
>Mature_404_residues
MIQFVQAAHIASGSIRSAKLRSALTTLGIVIGVAAVIINASLGASFNQFFTDEVSSVGSNFIIAYSDQPNLFYDSELEII
KNTPGILGVSPRKTVSGEINYLSDVKSVSIVGVNGDFQEIQGIKMEEGSFLTDKDIYSAVLGYDLAKEEFGRSISHRSSV
DIAFRQEDGTLVIKKFKVKGILEDSKETIVGGDGSTDMIVYIPISTMNEMTGEKDYGAFFAMAESSENIGSISKDVDKRL
ARSFGISERDLNNEDAKPYTVFDQADVLEETGALGKALSTFLLVLALISLFVGSIGIMNIMLVTVTERTREIGIMKSVGY
SSSNILSLFLLESIMVSSLGGLLGTAIGGFGAYILEEALKLPPVFPFKLIEIGILISVLVGVGAGLYPARKAANMNPVDA
LRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=423, Percent_Identity=29.5508274231678, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43377; Mature: 43377

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQFVQAAHIASGSIRSAKLRSALTTLGIVIGVAAVIINASLGASFNQFFTDEVSSVGSN
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
FIIAYSDQPNLFYDSELEIIKNTPGILGVSPRKTVSGEINYLSDVKSVSIVGVNGDFQEI
EEEEECCCCCEEECCCHHEEECCCCEEECCCCCCCCCCCHHHHCCCEEEEEECCCCHHHH
QGIKMEEGSFLTDKDIYSAVLGYDLAKEEFGRSISHRSSVDIAFRQEDGTLVIKKFKVKG
CCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEEEEEHH
ILEDSKETIVGGDGSTDMIVYIPISTMNEMTGEKDYGAFFAMAESSENIGSISKDVDKRL
HHCCCCCEEECCCCCCCEEEEEECCHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHH
ARSFGISERDLNNEDAKPYTVFDQADVLEETGALGKALSTFLLVLALISLFVGSIGIMNI
HHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
MLVTVTERTREIGIMKSVGYSSSNILSLFLLESIMVSSLGGLLGTAIGGFGAYILEEALK
EEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPPVFPFKLIEIGILISVLVGVGAGLYPARKAANMNPVDALRYE
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHCCCC
>Mature Secondary Structure
MIQFVQAAHIASGSIRSAKLRSALTTLGIVIGVAAVIINASLGASFNQFFTDEVSSVGSN
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
FIIAYSDQPNLFYDSELEIIKNTPGILGVSPRKTVSGEINYLSDVKSVSIVGVNGDFQEI
EEEEECCCCCEEECCCHHEEECCCCEEECCCCCCCCCCCHHHHCCCEEEEEECCCCHHHH
QGIKMEEGSFLTDKDIYSAVLGYDLAKEEFGRSISHRSSVDIAFRQEDGTLVIKKFKVKG
CCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEEEEEHH
ILEDSKETIVGGDGSTDMIVYIPISTMNEMTGEKDYGAFFAMAESSENIGSISKDVDKRL
HHCCCCCEEECCCCCCCEEEEEECCHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHH
ARSFGISERDLNNEDAKPYTVFDQADVLEETGALGKALSTFLLVLALISLFVGSIGIMNI
HHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
MLVTVTERTREIGIMKSVGYSSSNILSLFLLESIMVSSLGGLLGTAIGGFGAYILEEALK
EEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPPVFPFKLIEIGILISVLVGVGAGLYPARKAANMNPVDALRYE
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA