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The map label for this gene is 21227045

Identifier: 21227045

GI number: 21227045

Start: 1117122

End: 1117865

Strand: Direct

Name: 21227045

Synonym: MM_0943

Alternate gene names: NA

Gene position: 1117122-1117865 (Clockwise)

Preceding gene: 298205308

Following gene: 21227046

Centisome position: 27.27

GC content: 48.25

Gene sequence:

>744_bases
TTGCAGGTGGAAGCACACCTCCAGAAGATTATTGAAAAGGACGGAAAAGTTCATCTTACCCTTATCGATCCGGCGTCCCA
GACGCCTGATAGAGCCGCCGAAATTGCTCTTGCAGCAGTTGAAGGGGGCACTGATGCCATCATGATAGGGGGCTCAACCG
GAGCGTCGGGAACCCTGTTAGATGAGACTGTAATAAAAATCAAAGAGAATATACACGTCCCCACAATCCTTTTCCCGGGA
AGCTCAGCCGGGCTCAGTAAGTACGCAGATGCGGTGTTTTTTATGAGCCTTTTGAACTCAAGGGATCTGGGATATGTAAT
TACAAACCAGGTTCTTGGAGCTCCGCTTGTATACAGAAGCCAGATCGAGCCAATCTCCATGGCATACCTTATAGTTGAAC
CAGGAGGCACTGTTGGCTGGGTGGGGGACGCCAAACTGATTCCAAGAAAGAAGCCTGAAATTGCCGCAGTCTATGCTCTT
GCAGGCAAATATCTTGGCATGCATTATACCTATCTGGAAGCAGGATCCGGGGCTGATTCTCCAGTCAACCCTGAAATGAT
AGGGGCTGTCAAGCAGGTACTTGGAGAAAACAAACTTATTGTTGGCGGCGGGATAAGAAACGCGGAAACAGCAAAGATCT
GTACCTCTGCAGGTGCGGATATGATCGTCACCGGCACAGTTGTTGAAGAAGTAAAAGACGTTACTGCAAAGGTGGCTGAG
ATTGTATCAGCCATAAAAAGATAA

Upstream 100 bases:

>100_bases
GTGTAATGCCAGAAACGCTACAAGGGCAACCCGCTGCAGAAAGTGCGGTTCCAGCGCTCTTCGCGTAAAATCCAAGGAAT
CCAAGGGAGCATGATCTTTT

Downstream 100 bases:

>100_bases
GTGCCTGTTAAGGGCTCAAGGTGTGCTACCTGCTTATTGCATCAAAAAGATTTGTTGCGCTTGACCGATTTTAAACATTA
ATATTTTTGTGGTTCTGAAA

Product: geranylgeranylglyceryl phosphate synthase-like protein

Products: NA

Alternate protein names: GGGP synthase; GGGPS; (S)-3-O-geranylgeranylglyceryl phosphate synthase; Phosphoglycerol geranylgeranyltransferase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MQVEAHLQKIIEKDGKVHLTLIDPASQTPDRAAEIALAAVEGGTDAIMIGGSTGASGTLLDETVIKIKENIHVPTILFPG
SSAGLSKYADAVFFMSLLNSRDLGYVITNQVLGAPLVYRSQIEPISMAYLIVEPGGTVGWVGDAKLIPRKKPEIAAVYAL
AGKYLGMHYTYLEAGSGADSPVNPEMIGAVKQVLGENKLIVGGGIRNAETAKICTSAGADMIVTGTVVEEVKDVTAKVAE
IVSAIKR

Sequences:

>Translated_247_residues
MQVEAHLQKIIEKDGKVHLTLIDPASQTPDRAAEIALAAVEGGTDAIMIGGSTGASGTLLDETVIKIKENIHVPTILFPG
SSAGLSKYADAVFFMSLLNSRDLGYVITNQVLGAPLVYRSQIEPISMAYLIVEPGGTVGWVGDAKLIPRKKPEIAAVYAL
AGKYLGMHYTYLEAGSGADSPVNPEMIGAVKQVLGENKLIVGGGIRNAETAKICTSAGADMIVTGTVVEEVKDVTAKVAE
IVSAIKR
>Mature_247_residues
MQVEAHLQKIIEKDGKVHLTLIDPASQTPDRAAEIALAAVEGGTDAIMIGGSTGASGTLLDETVIKIKENIHVPTILFPG
SSAGLSKYADAVFFMSLLNSRDLGYVITNQVLGAPLVYRSQIEPISMAYLIVEPGGTVGWVGDAKLIPRKKPEIAAVYAL
AGKYLGMHYTYLEAGSGADSPVNPEMIGAVKQVLGENKLIVGGGIRNAETAKICTSAGADMIVTGTVVEEVKDVTAKVAE
IVSAIKR

Specific function: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membr

COG id: COG1646

COG function: function code R; Predicted phosphate-binding enzymes, TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GGGP synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008205
- InterPro:   IPR010946 [H]

Pfam domain/function: PF01884 PcrB [H]

EC number: =2.5.1.41 [H]

Molecular weight: Translated: 25888; Mature: 25888

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVEAHLQKIIEKDGKVHLTLIDPASQTPDRAAEIALAAVEGGTDAIMIGGSTGASGTLL
CCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHEEEEEECCCCCEEEEECCCCCCCCHH
DETVIKIKENIHVPTILFPGSSAGLSKYADAVFFMSLLNSRDLGYVITNQVLGAPLVYRS
HHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCEEECC
QIEPISMAYLIVEPGGTVGWVGDAKLIPRKKPEIAAVYALAGKYLGMHYTYLEAGSGADS
CCCCEEEEEEEECCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCEEEEEEECCCCCCC
PVNPEMIGAVKQVLGENKLIVGGGIRNAETAKICTSAGADMIVTGTVVEEVKDVTAKVAE
CCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
IVSAIKR
HHHHHCC
>Mature Secondary Structure
MQVEAHLQKIIEKDGKVHLTLIDPASQTPDRAAEIALAAVEGGTDAIMIGGSTGASGTLL
CCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHEEEEEECCCCCEEEEECCCCCCCCHH
DETVIKIKENIHVPTILFPGSSAGLSKYADAVFFMSLLNSRDLGYVITNQVLGAPLVYRS
HHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCEEECC
QIEPISMAYLIVEPGGTVGWVGDAKLIPRKKPEIAAVYALAGKYLGMHYTYLEAGSGADS
CCCCEEEEEEEECCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCEEEEEEECCCCCCC
PVNPEMIGAVKQVLGENKLIVGGGIRNAETAKICTSAGADMIVTGTVVEEVKDVTAKVAE
CCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
IVSAIKR
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]