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The map label for this gene is nudG [C]

Identifier: 21227022

GI number: 21227022

Start: 1086581

End: 1087018

Strand: Reverse

Name: nudG [C]

Synonym: MM_0920

Alternate gene names: 21227022

Gene position: 1087018-1086581 (Counterclockwise)

Preceding gene: 21227026

Following gene: 21227010

Centisome position: 26.54

GC content: 46.35

Gene sequence:

>438_bases
ATGAACCTGGAGAAACCTTATATCATTTCCGTATATGCTCTCATCCGGAACGAAAAAGGGGAATTTCTGCTGCTCAGGCG
CTCGGAAAATTCCCGCACCAATGCAGGAAAGTGGGACCTTCCGGGAGGAAAGGTAAACCCGGACGAGTCTCTTAAAGAAG
GGGTTGCGCGTGAAGTCTGGGAGGAAACCGGAATTACAATGGTTCCCGGGGATATTGCAGGGCAGGTAAACTTTGAACTC
ACTGAAAAGAAGGTCATTGCTATCGTGTTTGATGGGGGGTATGTTGTCGCTGACGTTAAATTGAGCTATGAGCACATTGA
ATATTCCTGGGTCTCGCTGGAAAAGATTCTCGGTATGGAGACGCTCCCGGCTTATTTCCGGGATTTCTTTGAAAGGTTTG
ATCGTGAGAACAAAAAACCTTCAAAGCTCTTTATTTAA

Upstream 100 bases:

>100_bases
TTTGAAAATGCTTTTTGAGAATGAGCTTTAATTGTAATTTTTACCGTGAAAATCTTGAAAGAGCCATTCTTTAAGGCAGA
GAAATTGTAGATAATATTAC

Downstream 100 bases:

>100_bases
TCTGAGTATTGCATTTTTTATCCTTTGGATTTTTTATTCTTTAAAATACTCATCTTCGAGTTTTTTTCTTTTTCTTCGGC
TTTTCTGCCAGCTTATCCCC

Product: MutT-like protein

Products: CMP; diphosphate [C]

Alternate protein names: ORF154 [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MNLEKPYIISVYALIRNEKGEFLLLRRSENSRTNAGKWDLPGGKVNPDESLKEGVAREVWEETGITMVPGDIAGQVNFEL
TEKKVIAIVFDGGYVVADVKLSYEHIEYSWVSLEKILGMETLPAYFRDFFERFDRENKKPSKLFI

Sequences:

>Translated_145_residues
MNLEKPYIISVYALIRNEKGEFLLLRRSENSRTNAGKWDLPGGKVNPDESLKEGVAREVWEETGITMVPGDIAGQVNFEL
TEKKVIAIVFDGGYVVADVKLSYEHIEYSWVSLEKILGMETLPAYFRDFFERFDRENKKPSKLFI
>Mature_145_residues
MNLEKPYIISVYALIRNEKGEFLLLRRSENSRTNAGKWDLPGGKVNPDESLKEGVAREVWEETGITMVPGDIAGQVNFEL
TEKKVIAIVFDGGYVVADVKLSYEHIEYSWVSLEKILGMETLPAYFRDFFERFDRENKKPSKLFI

Specific function: Specific For Pyrimidine Substrates. Acts On 5-Methyl- Dctp, Ctp And Dctp In Decreasing Order. [C]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 16681; Mature: 16681

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLEKPYIISVYALIRNEKGEFLLLRRSENSRTNAGKWDLPGGKVNPDESLKEGVAREVW
CCCCCCHHEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
EETGITMVPGDIAGQVNFELTEKKVIAIVFDGGYVVADVKLSYEHIEYSWVSLEKILGME
HHCCCEEECCCCCCEEEEEEECCEEEEEEECCCEEEEEEEEEEEHEEEHHHHHHHHHCCC
TLPAYFRDFFERFDRENKKPSKLFI
HHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNLEKPYIISVYALIRNEKGEFLLLRRSENSRTNAGKWDLPGGKVNPDESLKEGVAREVW
CCCCCCHHEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
EETGITMVPGDIAGQVNFELTEKKVIAIVFDGGYVVADVKLSYEHIEYSWVSLEKILGME
HHCCCEEECCCCCCEEEEEEECCEEEEEEECCCEEEEEEEEEEEHEEEHHHHHHHHHCCC
TLPAYFRDFFERFDRENKKPSKLFI
HHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CTP; H2O [C]

Specific reaction: CTP + H2O = CMP + diphosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934842 [H]