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The map label for this gene is 21226844

Identifier: 21226844

GI number: 21226844

Start: 888778

End: 889860

Strand: Direct

Name: 21226844

Synonym: MM_0742

Alternate gene names: NA

Gene position: 888778-889860 (Clockwise)

Preceding gene: 21226843

Following gene: 21226848

Centisome position: 21.7

GC content: 44.78

Gene sequence:

>1083_bases
ATGGAGAAGAGTGGGACGAAGGAGAAGAGTATGCCTGAGGGAACTGAAGAAAGGGAGCTCGACTTTTTCAGTAAATACCT
ATCTATCTGGGTTGCGGTCTGCATCATACTCGGAACCGCACTGGGATATGCTTTTCCAGGATTTGCGCGCGCCCTTGGTG
GAATTGAAATTGCAGAAGTTTCGATCCCCGTAGCTGTAGTACTCCTGATCATGATGTATCCTATAATGCTTAAAATTAAT
TTTGAAGAGATTTTGAATGTCGAAGCGAACCTGAAACCCCTCGTCCTGACCCTTGTCGTAAACTGGTTGATAAAGCCCTT
TACAATGGCTTTTGTTGCGTGGTTTTTTATGAGCGTTCTTTTTGAAGCCCTGATCCCTGCTGACCTTCAGGCACAGTACA
TTGCAGGCATGATTCTTCTGGGGCTTGCCCCCTGTACGGCGATGGTACTTGTCTGGACCTACCTTGCAAGAGCAAATATT
AACTATGCTTTAATTCAGGTCTCAGTAAATGACCTTATAATCCTGGTCCTTTTCGCCCCGCTGGGAAAATTCCTGCTCGG
AGTCACAACTGACTTCCCTGTTCCTCTAATGACAATCTTTGTCTCGGTCCTGTTTTATGTGGCAATTCCTCTCGGTCTTG
CTGTGCTGACAAGGCAGGTAATGATAAAGAAAAAAGGCATTTCCTGGTTTGAAAATAAACTTATACGAAAAACACAATGG
ATCACTCCTGCCGGGCTTTTGATAACTCTTGTCCTGATTTTTATATTCCAGGGAAGCAACATCATTAATTACCCTCTGCA
TATCCTCCTGATTGCGATCCCCCTTGTTCTGCAAACTTACCTGATCTTCTGGATAGGTTATGCAGGAGCGAAATACCTTA
AAATCCCTTATATGGAAGCTGCACCCTCGACCTTTATCGGTGCCAGCAATTTCTTTGAACTGGCGGTAGCAGTAGCTTTA
ATTCTATTTGGAATGGAATCAGGGGCAGCTCTCGCGACAGTTGTGGGAGTGCTTGTGGAAGTGCCTGTTATGCTTTCCCT
TGTGAAAATTATGGAAAGGAGCAGGGAGAAGTTCAAGTTCTGA

Upstream 100 bases:

>100_bases
AAAGGGGATTTGATAGACCTGATACTCGGGAGCACGGCAGAAAGCGTTCTCCGAAAAACCATAAAACCCGTATTAATTAT
CCCTGCGAGCAAAGAATTTG

Downstream 100 bases:

>100_bases
TGAGATTAGACATGGGAAAAAAGCAAAAAATAGAACAGATTGAAAATCAATTGATAAAACGAACTCAAAGCCTTAGCCCG
TTATTTATTTACCGCAGCAG

Product: arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MEKSGTKEKSMPEGTEERELDFFSKYLSIWVAVCIILGTALGYAFPGFARALGGIEIAEVSIPVAVVLLIMMYPIMLKIN
FEEILNVEANLKPLVLTLVVNWLIKPFTMAFVAWFFMSVLFEALIPADLQAQYIAGMILLGLAPCTAMVLVWTYLARANI
NYALIQVSVNDLIILVLFAPLGKFLLGVTTDFPVPLMTIFVSVLFYVAIPLGLAVLTRQVMIKKKGISWFENKLIRKTQW
ITPAGLLITLVLIFIFQGSNIINYPLHILLIAIPLVLQTYLIFWIGYAGAKYLKIPYMEAAPSTFIGASNFFELAVAVAL
ILFGMESGAALATVVGVLVEVPVMLSLVKIMERSREKFKF

Sequences:

>Translated_360_residues
MEKSGTKEKSMPEGTEERELDFFSKYLSIWVAVCIILGTALGYAFPGFARALGGIEIAEVSIPVAVVLLIMMYPIMLKIN
FEEILNVEANLKPLVLTLVVNWLIKPFTMAFVAWFFMSVLFEALIPADLQAQYIAGMILLGLAPCTAMVLVWTYLARANI
NYALIQVSVNDLIILVLFAPLGKFLLGVTTDFPVPLMTIFVSVLFYVAIPLGLAVLTRQVMIKKKGISWFENKLIRKTQW
ITPAGLLITLVLIFIFQGSNIINYPLHILLIAIPLVLQTYLIFWIGYAGAKYLKIPYMEAAPSTFIGASNFFELAVAVAL
ILFGMESGAALATVVGVLVEVPVMLSLVKIMERSREKFKF
>Mature_360_residues
MEKSGTKEKSMPEGTEERELDFFSKYLSIWVAVCIILGTALGYAFPGFARALGGIEIAEVSIPVAVVLLIMMYPIMLKIN
FEEILNVEANLKPLVLTLVVNWLIKPFTMAFVAWFFMSVLFEALIPADLQAQYIAGMILLGLAPCTAMVLVWTYLARANI
NYALIQVSVNDLIILVLFAPLGKFLLGVTTDFPVPLMTIFVSVLFYVAIPLGLAVLTRQVMIKKKGISWFENKLIRKTQW
ITPAGLLITLVLIFIFQGSNIINYPLHILLIAIPLVLQTYLIFWIGYAGAKYLKIPYMEAAPSTFIGASNFFELAVAVAL
ILFGMESGAALATVVGVLVEVPVMLSLVKIMERSREKFKF

Specific function: Unknown

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=335, Percent_Identity=29.8507462686567, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 39963; Mature: 39963

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKSGTKEKSMPEGTEERELDFFSKYLSIWVAVCIILGTALGYAFPGFARALGGIEIAEV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEHH
SIPVAVVLLIMMYPIMLKINFEEILNVEANLKPLVLTLVVNWLIKPFTMAFVAWFFMSVL
HHHHHHHHHHHHHHHHHEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEALIPADLQAQYIAGMILLGLAPCTAMVLVWTYLARANINYALIQVSVNDLIILVLFAP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHH
LGKFLLGVTTDFPVPLMTIFVSVLFYVAIPLGLAVLTRQVMIKKKGISWFENKLIRKTQW
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
ITPAGLLITLVLIFIFQGSNIINYPLHILLIAIPLVLQTYLIFWIGYAGAKYLKIPYMEA
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHC
APSTFIGASNFFELAVAVALILFGMESGAALATVVGVLVEVPVMLSLVKIMERSREKFKF
CCCHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKSGTKEKSMPEGTEERELDFFSKYLSIWVAVCIILGTALGYAFPGFARALGGIEIAEV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEHH
SIPVAVVLLIMMYPIMLKINFEEILNVEANLKPLVLTLVVNWLIKPFTMAFVAWFFMSVL
HHHHHHHHHHHHHHHHHEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEALIPADLQAQYIAGMILLGLAPCTAMVLVWTYLARANINYALIQVSVNDLIILVLFAP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHH
LGKFLLGVTTDFPVPLMTIFVSVLFYVAIPLGLAVLTRQVMIKKKGISWFENKLIRKTQW
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
ITPAGLLITLVLIFIFQGSNIINYPLHILLIAIPLVLQTYLIFWIGYAGAKYLKIPYMEA
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHC
APSTFIGASNFFELAVAVALILFGMESGAALATVVGVLVEVPVMLSLVKIMERSREKFKF
CCCHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]