Click here to switch to the map view.

The map label for this gene is ocd2 [H]

Identifier: 21226199

GI number: 21226199

Start: 125736

End: 126740

Strand: Reverse

Name: ocd2 [H]

Synonym: MM_0097

Alternate gene names: 21226199

Gene position: 126740-125736 (Counterclockwise)

Preceding gene: 21226201

Following gene: 21226196

Centisome position: 3.09

GC content: 49.15

Gene sequence:

>1005_bases
ATGGCTCCGATTGAGGGTTGTAATATGGAAGTTTTGTGGCTGGCTCAGGAAGAAGTAAAAAGTGTTATGGACATGCATTC
CGATATGCAGGTAGTTGAAAGGGCTTTCAGGCAGCACGGGCTTGGCAAGGTGCAGATGCCGCCTAAGTCCTATCTTTACT
ATACTGCTTACAACGGCGACCTGCGTACAATGCCTGCATACCTTGAAGAAGAGGACATTACCGGCGTAAAGATTGTAAAT
GTCCACCCCGGAAACCCCACGCGCAACCTGCCCACAGTAATGGCGCTGATCATTCTTATTTCCCCTGAGACCGGAGCCCC
TGTAGCGATCATGGACGGGACCTACCTGACAGATATCAGGACAGGTGCAGCCGGTGGAATTGCCGCAAAATACCTTGCAA
GGAAAGACTCGAAAGTAATCGGGCTTGTAGGCGCAGGAAACCAGGCAAGGACCCAGCTTGAATCTCTTTGTGAGGTTTTT
GAGCCTGAATCTGTCAGGATTACCTCCAGGACAAAGGAAAGCTGTGAACAGTTTATCCGGGATATGGCAGATATCGTGCC
CTGCGAAATTCATTATGAAGAAAGCATTGAAAAGGTCTGTGACTGTGATATCCTTGTCACAACAACCCCTTCCAGAAAAC
CAATTGTAAAAGCCAGCTGGATCAAAGAAGGCACTCATATAAATGCAATAGGCGCAGATGCAGTAGGAAAAGAAGAACTT
GACCCCGAAATTCTCCTCCGTGCCAAGGTTATTGTCGACGACATGATCCAGGCTCTCCATTCCGGAGAAGTGAACGTCCC
CCTATCCAAACACTATATCTCGGAAAATGATATCCATGCCCAGCTCGGAGAAGTGATGGTCGGTCTCAAGCCCGGAAGGA
CCAGTGAGGAAGAGATTACGATATTTGATTCCACAGGGCTTGCAATCCAGGATGTAGCAACCGCACACCTGGTCTATGAA
AGGGCTGTCCGTGAAGGGCTTGGCAGACAGGTCCGCATGTTCTGA

Upstream 100 bases:

>100_bases
TAATTTGCCTGTTTATCTGTCGGTTTCTATTCCGGTTTATTCAATTTAAGTCTGGTTTTCAACCGGAAGCCAGCTTATAT
TCAGAATGTGAGGTATCTTT

Downstream 100 bases:

>100_bases
TGGTTGTTTAGACCTCTTTACAATTGTTTAGCCCTCTTTACTTGGCATGAAAGTCCATGATGAGAAAACTCATCACGTAC
TCTCTCCTTCCTTTTTTCCC

Product: alanine dehydrogenase

Products: NA

Alternate protein names: OCD 2 [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAPIEGCNMEVLWLAQEEVKSVMDMHSDMQVVERAFRQHGLGKVQMPPKSYLYYTAYNGDLRTMPAYLEEEDITGVKIVN
VHPGNPTRNLPTVMALIILISPETGAPVAIMDGTYLTDIRTGAAGGIAAKYLARKDSKVIGLVGAGNQARTQLESLCEVF
EPESVRITSRTKESCEQFIRDMADIVPCEIHYEESIEKVCDCDILVTTTPSRKPIVKASWIKEGTHINAIGADAVGKEEL
DPEILLRAKVIVDDMIQALHSGEVNVPLSKHYISENDIHAQLGEVMVGLKPGRTSEEEITIFDSTGLAIQDVATAHLVYE
RAVREGLGRQVRMF

Sequences:

>Translated_334_residues
MAPIEGCNMEVLWLAQEEVKSVMDMHSDMQVVERAFRQHGLGKVQMPPKSYLYYTAYNGDLRTMPAYLEEEDITGVKIVN
VHPGNPTRNLPTVMALIILISPETGAPVAIMDGTYLTDIRTGAAGGIAAKYLARKDSKVIGLVGAGNQARTQLESLCEVF
EPESVRITSRTKESCEQFIRDMADIVPCEIHYEESIEKVCDCDILVTTTPSRKPIVKASWIKEGTHINAIGADAVGKEEL
DPEILLRAKVIVDDMIQALHSGEVNVPLSKHYISENDIHAQLGEVMVGLKPGRTSEEEITIFDSTGLAIQDVATAHLVYE
RAVREGLGRQVRMF
>Mature_333_residues
APIEGCNMEVLWLAQEEVKSVMDMHSDMQVVERAFRQHGLGKVQMPPKSYLYYTAYNGDLRTMPAYLEEEDITGVKIVNV
HPGNPTRNLPTVMALIILISPETGAPVAIMDGTYLTDIRTGAAGGIAAKYLARKDSKVIGLVGAGNQARTQLESLCEVFE
PESVRITSRTKESCEQFIRDMADIVPCEIHYEESIEKVCDCDILVTTTPSRKPIVKASWIKEGTHINAIGADAVGKEELD
PEILLRAKVIVDDMIQALHSGEVNVPLSKHYISENDIHAQLGEVMVGLKPGRTSEEEITIFDSTGLAIQDVATAHLVYER
AVREGLGRQVRMF

Specific function: Unknown

COG id: COG2423

COG function: function code E; Predicted ornithine cyclodeaminase, mu-crystallin homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ornithine cyclodeaminase family [H]

Homologues:

Organism=Homo sapiens, GI4503065, Length=282, Percent_Identity=36.8794326241135, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI62241008, Length=277, Percent_Identity=36.8231046931408, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24642678, Length=295, Percent_Identity=30.1694915254237, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003462 [H]

Pfam domain/function: PF02423 OCD_Mu_crystall [H]

EC number: =4.3.1.12 [H]

Molecular weight: Translated: 36850; Mature: 36719

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPIEGCNMEVLWLAQEEVKSVMDMHSDMQVVERAFRQHGLGKVQMPPKSYLYYTAYNGD
CCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEECCC
LRTMPAYLEEEDITGVKIVNVHPGNPTRNLPTVMALIILISPETGAPVAIMDGTYLTDIR
CCCCCCHHCCCCCCCEEEEEECCCCCCCCHHHHEEEEEEECCCCCCCEEEECCCEEEEEC
TGAAGGIAAKYLARKDSKVIGLVGAGNQARTQLESLCEVFEPESVRITSRTKESCEQFIR
CCCCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
DMADIVPCEIHYEESIEKVCDCDILVTTTPSRKPIVKASWIKEGTHINAIGADAVGKEEL
HHHHHCCCEEEHHHHHHHHHCCCEEEEECCCCCCCEEEHHHCCCCEEEEECCCCCCCCCC
DPEILLRAKVIVDDMIQALHSGEVNVPLSKHYISENDIHAQLGEVMVGLKPGRTSEEEIT
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHEECCCCCCCCCEEE
IFDSTGLAIQDVATAHLVYERAVREGLGRQVRMF
EEECCCCCHHHHHHHHHHHHHHHHHCCCCEECCC
>Mature Secondary Structure 
APIEGCNMEVLWLAQEEVKSVMDMHSDMQVVERAFRQHGLGKVQMPPKSYLYYTAYNGD
CCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEECCC
LRTMPAYLEEEDITGVKIVNVHPGNPTRNLPTVMALIILISPETGAPVAIMDGTYLTDIR
CCCCCCHHCCCCCCCEEEEEECCCCCCCCHHHHEEEEEEECCCCCCCEEEECCCEEEEEC
TGAAGGIAAKYLARKDSKVIGLVGAGNQARTQLESLCEVFEPESVRITSRTKESCEQFIR
CCCCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
DMADIVPCEIHYEESIEKVCDCDILVTTTPSRKPIVKASWIKEGTHINAIGADAVGKEEL
HHHHHCCCEEEHHHHHHHHHCCCEEEEECCCCCCCEEEHHHCCCCEEEEECCCCCCCCCC
DPEILLRAKVIVDDMIQALHSGEVNVPLSKHYISENDIHAQLGEVMVGLKPGRTSEEEIT
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHEECCCCCCCCCEEE
IFDSTGLAIQDVATAHLVYERAVREGLGRQVRMF
EEECCCCCHHHHHHHHHHHHHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]