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The map label for this gene is CpsG3 [H]

Identifier: 20809047

GI number: 20809047

Start: 2600455

End: 2602125

Strand: Reverse

Name: CpsG3 [H]

Synonym: TTE2704

Alternate gene names: 20809047

Gene position: 2602125-2600455 (Counterclockwise)

Preceding gene: 20809048

Following gene: 20809046

Centisome position: 96.75

GC content: 40.39

Gene sequence:

>1671_bases
GTGGAAAAAGAGACTTTGAAAAGGTATGAGGCGTGGCTAAATGACCCTGCCATATCCTATGAGGATAAAGAGAAATTGAA
GAAAATGTCTCCTGAGGAGATAAAAGAGGCCTTTTTTATGGACTTGGAATTTGGGACAGCGGGATTAAGGGGAATTATGG
GGCTTGGAGCCAATAGAATGAATTTTTATACGGTAGGCAGGGCAACCCAGGCTCTTGCTAATTACATAAACAAGACGGTA
GAGGAAGAAAAAAGTGTGGCAGTTTCTTACGATACCAGGAAATTTTCTAAAGAGTTTGCAGTGGAGTCAGCGCAGATACT
GGCCGCAAATGGAATAAAAGTTTATCTTTTTGACGATTTTAGACCCACGCCCCTTTTGTCTTTTGCTGTCAGGTTTTTAA
AGGCTACAGCTGGTATAATGATAACAGCGAGTCACAATCCTCCGGAATACAACGGATACAAGGTATATTGGTCAAATGGC
GCTCAGATTATTCCACCCCATGATAAAGGCATTATAGAGGAGTACGAGAAACTGTCTTTTGCGGATGTAAAAAGAATGTC
CTTTGATGAGGCTAAAGATAAGGGCTTTGTGGTCATGGTGGGGAAAGAGGTGGACTCTGCATATTTTGAAAAAGCCCTTT
CTTATTCTTTTGGGATTTCTTCAAAGGATTTAAAGATAGTGTATACTCCTCTCCATGGGACAGGTATTAAAATTGTCCCG
CCACTACTTGAGAAAGTTGGGTTTGATGTATATATTCAAAAAGAGCAGCAGATACCGGATGGAAGCTTTCCTACAGTGAG
CTATCCTAATCCAGAGTTTGATGAGGCCTTTGAGCTTGCTTTGAAAGATGCAAGAAGTATTGATGCGGATATAGTTGTGG
CTTCAGACCCGGACGCAGATAGGATGGGAGTTTTGGTAAAGCATAAAGGGGATTATGTGAGAATAGATGGAAATCAGATG
GGCATTTTGCTTTTGAATTTTCTTCTTACGATGTATTTTGAAAAGGGCATGCCAGAAAATCCGGCTGTTATAGAGTCTAT
TGTGTCTTCTAAGCTTTTTGCTAAAATTGCGAGGGCGCACGGGGTTGAGGTTTCTGAAGTGCTTACAGGTTTTAAGTGGA
TATGCAATGAAGCTGATAGGTTGAGAAAAGAAGGCAAAACGGTGTTTTTTGCCTATGAAGAAAGCTATGGATACAATGTG
GGAGATTTTGTTTACGACAAAGACTCAGGCACTCCTATAATGGTAACCTGTGAAATGGCTGCCTACTACAAAAAGAAGGG
CATGACTTTAGTTGATGCTTTAGAAGAGATTTATAAAAAATACGGTTACTACCTTGAAGACCAGCTTTCTCCTGTATATG
AAGGGGAAAAAGGGCTTAAGAAAATAAAGGGGATTATGGAAAGGCTAAGAGAAAAGCCAATTGAAAGTTTGGCAGGCCAC
AGGCTCACGCGTGTTGTAGATTATCTTAAAGGCTATGACAGGATATCGCCTTCAGATGTTTTAAAGATGGAATTTGGGGA
GAAGCTCATAGTATACGTTAGGCCCTCAGGCACAGAGCCTAAAATAAAATTCTATTTTATGGCAATGGAGATGGAGAATA
TAGAGGAGGCTAAAAAGCTTTTAAAAAGAGCTAAGGAAGAGCTTGTAAAAGTGCTGGATTTGGAAGAATAA

Upstream 100 bases:

>100_bases
TGGCTTATGCCGATGCCTTTTTTAATGGAAAATTGTATTAAAAAGAAAAGCCTTATGGTATAATAAAAGTAAAGATTTAG
CAAGGAAAGGCGGGATTTAA

Downstream 100 bases:

>100_bases
TAACCCGGTTTGCGAGGGGAAAGAATGGGTAAAAGGATATTTATAAAGGCTTTACTTTTCTTTTTTGCGGTAGTATTTGT
AATGGTATTTTTTGAAAATT

Product: phosphomannomutase

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MEKETLKRYEAWLNDPAISYEDKEKLKKMSPEEIKEAFFMDLEFGTAGLRGIMGLGANRMNFYTVGRATQALANYINKTV
EEEKSVAVSYDTRKFSKEFAVESAQILAANGIKVYLFDDFRPTPLLSFAVRFLKATAGIMITASHNPPEYNGYKVYWSNG
AQIIPPHDKGIIEEYEKLSFADVKRMSFDEAKDKGFVVMVGKEVDSAYFEKALSYSFGISSKDLKIVYTPLHGTGIKIVP
PLLEKVGFDVYIQKEQQIPDGSFPTVSYPNPEFDEAFELALKDARSIDADIVVASDPDADRMGVLVKHKGDYVRIDGNQM
GILLLNFLLTMYFEKGMPENPAVIESIVSSKLFAKIARAHGVEVSEVLTGFKWICNEADRLRKEGKTVFFAYEESYGYNV
GDFVYDKDSGTPIMVTCEMAAYYKKKGMTLVDALEEIYKKYGYYLEDQLSPVYEGEKGLKKIKGIMERLREKPIESLAGH
RLTRVVDYLKGYDRISPSDVLKMEFGEKLIVYVRPSGTEPKIKFYFMAMEMENIEEAKKLLKRAKEELVKVLDLEE

Sequences:

>Translated_556_residues
MEKETLKRYEAWLNDPAISYEDKEKLKKMSPEEIKEAFFMDLEFGTAGLRGIMGLGANRMNFYTVGRATQALANYINKTV
EEEKSVAVSYDTRKFSKEFAVESAQILAANGIKVYLFDDFRPTPLLSFAVRFLKATAGIMITASHNPPEYNGYKVYWSNG
AQIIPPHDKGIIEEYEKLSFADVKRMSFDEAKDKGFVVMVGKEVDSAYFEKALSYSFGISSKDLKIVYTPLHGTGIKIVP
PLLEKVGFDVYIQKEQQIPDGSFPTVSYPNPEFDEAFELALKDARSIDADIVVASDPDADRMGVLVKHKGDYVRIDGNQM
GILLLNFLLTMYFEKGMPENPAVIESIVSSKLFAKIARAHGVEVSEVLTGFKWICNEADRLRKEGKTVFFAYEESYGYNV
GDFVYDKDSGTPIMVTCEMAAYYKKKGMTLVDALEEIYKKYGYYLEDQLSPVYEGEKGLKKIKGIMERLREKPIESLAGH
RLTRVVDYLKGYDRISPSDVLKMEFGEKLIVYVRPSGTEPKIKFYFMAMEMENIEEAKKLLKRAKEELVKVLDLEE
>Mature_556_residues
MEKETLKRYEAWLNDPAISYEDKEKLKKMSPEEIKEAFFMDLEFGTAGLRGIMGLGANRMNFYTVGRATQALANYINKTV
EEEKSVAVSYDTRKFSKEFAVESAQILAANGIKVYLFDDFRPTPLLSFAVRFLKATAGIMITASHNPPEYNGYKVYWSNG
AQIIPPHDKGIIEEYEKLSFADVKRMSFDEAKDKGFVVMVGKEVDSAYFEKALSYSFGISSKDLKIVYTPLHGTGIKIVP
PLLEKVGFDVYIQKEQQIPDGSFPTVSYPNPEFDEAFELALKDARSIDADIVVASDPDADRMGVLVKHKGDYVRIDGNQM
GILLLNFLLTMYFEKGMPENPAVIESIVSSKLFAKIARAHGVEVSEVLTGFKWICNEADRLRKEGKTVFFAYEESYGYNV
GDFVYDKDSGTPIMVTCEMAAYYKKKGMTLVDALEEIYKKYGYYLEDQLSPVYEGEKGLKKIKGIMERLREKPIESLAGH
RLTRVVDYLKGYDRISPSDVLKMEFGEKLIVYVRPSGTEPKIKFYFMAMEMENIEEAKKLLKRAKEELVKVLDLEE

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=531, Percent_Identity=36.5348399246704, Blast_Score=305, Evalue=8e-83,
Organism=Homo sapiens, GI31377548, Length=589, Percent_Identity=33.276740237691, Blast_Score=265, Evalue=8e-71,
Organism=Homo sapiens, GI21361621, Length=446, Percent_Identity=25.7847533632287, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1786904, Length=559, Percent_Identity=26.8336314847943, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789566, Length=204, Percent_Identity=32.3529411764706, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71993870, Length=508, Percent_Identity=35.2362204724409, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI71993878, Length=324, Percent_Identity=34.8765432098765, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6323934, Length=558, Percent_Identity=34.2293906810036, Blast_Score=255, Evalue=1e-68,
Organism=Drosophila melanogaster, GI20129809, Length=564, Percent_Identity=33.5106382978723, Blast_Score=278, Evalue=6e-75,
Organism=Drosophila melanogaster, GI24651977, Length=577, Percent_Identity=32.5823223570191, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24653722, Length=490, Percent_Identity=32.0408163265306, Blast_Score=220, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 63179; Mature: 63179

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKETLKRYEAWLNDPAISYEDKEKLKKMSPEEIKEAFFMDLEFGTAGLRGIMGLGANRM
CCHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
NFYTVGRATQALANYINKTVEEEKSVAVSYDTRKFSKEFAVESAQILAANGIKVYLFDDF
EEEEECHHHHHHHHHHHHHHHHHHCEEEEECHHHHHHHHHHHHHHEEEECCEEEEEECCC
RPTPLLSFAVRFLKATAGIMITASHNPPEYNGYKVYWSNGAQIIPPHDKGIIEEYEKLSF
CCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEECCCCEECCCCCCCHHHHHHHCCH
ADVKRMSFDEAKDKGFVVMVGKEVDSAYFEKALSYSFGISSKDLKIVYTPLHGTGIKIVP
HHHHHHCCHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEECC
PLLEKVGFDVYIQKEQQIPDGSFPTVSYPNPEFDEAFELALKDARSIDADIVVASDPDAD
HHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCH
RMGVLVKHKGDYVRIDGNQMGILLLNFLLTMYFEKGMPENPAVIESIVSSKLFAKIARAH
HCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
GVEVSEVLTGFKWICNEADRLRKEGKTVFFAYEESYGYNVGDFVYDKDSGTPIMVTCEMA
CCCHHHHHHHHHHHHCHHHHHHHCCCEEEEEEECCCCCCCCCEEEECCCCCEEEEEEHHH
AYYKKKGMTLVDALEEIYKKYGYYLEDQLSPVYEGEKGLKKIKGIMERLREKPIESLAGH
HHHHHCCCHHHHHHHHHHHHCCCEEHHCCCHHHCCHHHHHHHHHHHHHHHHCHHHHHHHH
RLTRVVDYLKGYDRISPSDVLKMEFGEKLIVYVRPSGTEPKIKFYFMAMEMENIEEAKKL
HHHHHHHHHHCCCCCCHHHHHHEECCCEEEEEECCCCCCCCEEEEEEEEEHHHHHHHHHH
LKRAKEELVKVLDLEE
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEKETLKRYEAWLNDPAISYEDKEKLKKMSPEEIKEAFFMDLEFGTAGLRGIMGLGANRM
CCHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
NFYTVGRATQALANYINKTVEEEKSVAVSYDTRKFSKEFAVESAQILAANGIKVYLFDDF
EEEEECHHHHHHHHHHHHHHHHHHCEEEEECHHHHHHHHHHHHHHEEEECCEEEEEECCC
RPTPLLSFAVRFLKATAGIMITASHNPPEYNGYKVYWSNGAQIIPPHDKGIIEEYEKLSF
CCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEECCCCEECCCCCCCHHHHHHHCCH
ADVKRMSFDEAKDKGFVVMVGKEVDSAYFEKALSYSFGISSKDLKIVYTPLHGTGIKIVP
HHHHHHCCHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEECC
PLLEKVGFDVYIQKEQQIPDGSFPTVSYPNPEFDEAFELALKDARSIDADIVVASDPDAD
HHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCH
RMGVLVKHKGDYVRIDGNQMGILLLNFLLTMYFEKGMPENPAVIESIVSSKLFAKIARAH
HCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
GVEVSEVLTGFKWICNEADRLRKEGKTVFFAYEESYGYNVGDFVYDKDSGTPIMVTCEMA
CCCHHHHHHHHHHHHCHHHHHHHCCCEEEEEEECCCCCCCCCEEEECCCCCEEEEEEHHH
AYYKKKGMTLVDALEEIYKKYGYYLEDQLSPVYEGEKGLKKIKGIMERLREKPIESLAGH
HHHHHCCCHHHHHHHHHHHHCCCEEHHCCCHHHCCHHHHHHHHHHHHHHHHCHHHHHHHH
RLTRVVDYLKGYDRISPSDVLKMEFGEKLIVYVRPSGTEPKIKFYFMAMEMENIEEAKKL
HHHHHHHHHHCCCCCCHHHHHHEECCCEEEEEECCCCCCCCEEEEEEEEEHHHHHHHHHH
LKRAKEELVKVLDLEE
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]