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The map label for this gene is GppA [H]

Identifier: 20808800

GI number: 20808800

Start: 2333726

End: 2334631

Strand: Reverse

Name: GppA [H]

Synonym: TTE2442

Alternate gene names: 20808800

Gene position: 2334631-2333726 (Counterclockwise)

Preceding gene: 20808801

Following gene: 20808799

Centisome position: 86.81

GC content: 34.99

Gene sequence:

>906_bases
ATGAGAGTCTCTGCGATAGATATTGGAACAAATTCTGTCAGACAATTGATATGCGACGTAGAAGATGGCAGTTTAATTAG
ATTGCGTAAAGATGTAAAAATAACCCGTTTAGGGGAAGGATTAATAAAAACGGGTAGACTAAACCCTGGTGCTGTTCAGA
GAACTGTGGAGACGATAGAGGAATTTATATCAATGGCAGAGAAGGAAGGTGTAGATGAGATTTATGCTTTTGCTACTTCT
GCTATGAGAGAAGCTAAAAATAAGGAGCTATTTTTGGATAATTTTTCAAAATTTAATATAGCATTAGATATACTAGACGG
TGATACTGAAAGCCTATTTGGCTATATAGGTGCTGTCAAAGGGATAAAATTGGATAAAGCGTTGGTTATTGATATAGGAG
GAGGGAGTACAGAGTTAGCCTATAAAGGTTTTGAATTTATAAAAGAAAGTTTTGGTATAGGAGCAGTGAAACTTACAGAA
GAATTCGTAAAAAGTGACCCTCCCTCTTTAGAAGAATACAACGATATGAGGCTTTACATAATAGATACAGTGGTAAATTC
AATAGGCAAGTATAATGAAATTGAAAGGCTTGTTGGAATTGGAGGGACTATCACAAGTTTAGCAGCAGTATCACAGCAAT
TGGAAATTTATTCGGAGGAAAAAGTACACGGATATGTTCTAGAGAGGGAGGAAATAAAGAGAATTTTAGATAGATTTATG
TCCGTTTCTCTTGAGGAAAGGAAAAAAATAGCTGGTCTTCAGCCAGAAAGAGCCGATATAATAATTGCTGGAACAGCTAT
TTTACTTACTCTTTTAGAAATATTTAATAAAAAAGAAATTACTGTAAGCGAATGGGACAACCTAGAAGGAGCAGTGTTGT
ATAAGTTTGGCGGTATGAATATATAA

Upstream 100 bases:

>100_bases
AAAGCATTTAGATTCAAAAAGAAGAAATACAAGTTACAGAAGAAGCAATGGATATTAACTTCGGGGCCTCCCGAAGATTT
TTCATAAGTTGGGGGTTGTT

Downstream 100 bases:

>100_bases
TTTGTTTTGTATAGATGAGATATTTTGCTGTCTTTATGACAGCTTTTTTAATAATTGGATGAAATTGTACAAAAGAAAAA
TAAAAAATAATCGTCATCTC

Product: exopolyphosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MRVSAIDIGTNSVRQLICDVEDGSLIRLRKDVKITRLGEGLIKTGRLNPGAVQRTVETIEEFISMAEKEGVDEIYAFATS
AMREAKNKELFLDNFSKFNIALDILDGDTESLFGYIGAVKGIKLDKALVIDIGGGSTELAYKGFEFIKESFGIGAVKLTE
EFVKSDPPSLEEYNDMRLYIIDTVVNSIGKYNEIERLVGIGGTITSLAAVSQQLEIYSEEKVHGYVLEREEIKRILDRFM
SVSLEERKKIAGLQPERADIIIAGTAILLTLLEIFNKKEITVSEWDNLEGAVLYKFGGMNI

Sequences:

>Translated_301_residues
MRVSAIDIGTNSVRQLICDVEDGSLIRLRKDVKITRLGEGLIKTGRLNPGAVQRTVETIEEFISMAEKEGVDEIYAFATS
AMREAKNKELFLDNFSKFNIALDILDGDTESLFGYIGAVKGIKLDKALVIDIGGGSTELAYKGFEFIKESFGIGAVKLTE
EFVKSDPPSLEEYNDMRLYIIDTVVNSIGKYNEIERLVGIGGTITSLAAVSQQLEIYSEEKVHGYVLEREEIKRILDRFM
SVSLEERKKIAGLQPERADIIIAGTAILLTLLEIFNKKEITVSEWDNLEGAVLYKFGGMNI
>Mature_301_residues
MRVSAIDIGTNSVRQLICDVEDGSLIRLRKDVKITRLGEGLIKTGRLNPGAVQRTVETIEEFISMAEKEGVDEIYAFATS
AMREAKNKELFLDNFSKFNIALDILDGDTESLFGYIGAVKGIKLDKALVIDIGGGSTELAYKGFEFIKESFGIGAVKLTE
EFVKSDPPSLEEYNDMRLYIIDTVVNSIGKYNEIERLVGIGGTITSLAAVSQQLEIYSEEKVHGYVLEREEIKRILDRFM
SVSLEERKKIAGLQPERADIIIAGTAILLTLLEIFNKKEITVSEWDNLEGAVLYKFGGMNI

Specific function: Degradation Of Inorganic Polyphosphates. Orthophosphate Is Released Progressively From The Ends Of Polyphosphate Of Circa 500 Residues Long, While Chains Of Circa 15 Residues Compete Poorly With Polyphosphate As Substrate. [C]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=307, Percent_Identity=27.3615635179153, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 33478; Mature: 33478

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSAIDIGTNSVRQLICDVEDGSLIRLRKDVKITRLGEGLIKTGRLNPGAVQRTVETIE
CEEEEEECCHHHHHHHHHCCCCCCEEEEECCCEEEHHCCHHHHCCCCCHHHHHHHHHHHH
EFISMAEKEGVDEIYAFATSAMREAKNKELFLDNFSKFNIALDILDGDTESLFGYIGAVK
HHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEECCCHHHHHHHHHHHC
GIKLDKALVIDIGGGSTELAYKGFEFIKESFGIGAVKLTEEFVKSDPPSLEEYNDMRLYI
CCEECCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEE
IDTVVNSIGKYNEIERLVGIGGTITSLAAVSQQLEIYSEEKVHGYVLEREEIKRILDRFM
HHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHEEEECHHHHHHHHHHHH
SVSLEERKKIAGLQPERADIIIAGTAILLTLLEIFNKKEITVSEWDNLEGAVLYKFGGMN
CCCHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCC
I
C
>Mature Secondary Structure
MRVSAIDIGTNSVRQLICDVEDGSLIRLRKDVKITRLGEGLIKTGRLNPGAVQRTVETIE
CEEEEEECCHHHHHHHHHCCCCCCEEEEECCCEEEHHCCHHHHCCCCCHHHHHHHHHHHH
EFISMAEKEGVDEIYAFATSAMREAKNKELFLDNFSKFNIALDILDGDTESLFGYIGAVK
HHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEECCCHHHHHHHHHHHC
GIKLDKALVIDIGGGSTELAYKGFEFIKESFGIGAVKLTEEFVKSDPPSLEEYNDMRLYI
CCEECCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEE
IDTVVNSIGKYNEIERLVGIGGTITSLAAVSQQLEIYSEEKVHGYVLEREEIKRILDRFM
HHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHEEEECHHHHHHHHHHHH
SVSLEERKKIAGLQPERADIIIAGTAILLTLLEIFNKKEITVSEWDNLEGAVLYKFGGMN
CCCHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]